iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-110311

Ensembl Protein ID

Si029885m

UniProt Accession

K3ZTF5; K3ZTF5_SETIT

Genbank Protein ID

KQL26557.1

Protein Name

Ribosome biogenesis protein WDR12 homolog

Genbank Nucleotide ID

CM003529

Gene Name

LOC101765488; SETIT_029885mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si029885m.g	Si029885m	Si029885m

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-34	117.2	359	393
UBD/Beta-Prp	3.80e-40	138.9	264	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           H++++t++++  s+  +lvs+s Dg++++WDlrt 
   Q: 359  HSSWITACKWhpSSwFHLVSSSFDGKVMLWDLRTA 393
           ***********755677***************996 PP

UBD/Beta-Prp

   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtl..tggh 179
           g+ ++tl gh++ v+++++ + ++++ s+s+d  +r wd++  ++    +   +++ nc+   ++g +l+++G+ D ++r+Wd  k g+l   +  ++ h
   Q: 264  GSAISTLLGHTQCVTAVTWPE-QQTIYSASWDHSVRQWDVQAVKET--WNMFSEKALNCLDCGGEGsSLIAAGGSDPILRVWDPrKPGSLAPVFqfSS-H 359
           67899**************88.9******************99999..58888999***************************965566666665477.* PP
   S: 180  tdsvyslsfdsng.kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgs 245
            + ++  ++++++ ++lvs s dg+v lwdl+t   + ++  h+d v++ + + +++ ++sg++D  
   Q: 360  SSWITACKWHPSSwFHLVSSSFDGKVMLWDLRTAWPLASVDSHKDKVLCADWW-KGDSVISGGADSK 425
           ************9****************************************.8999999999976 PP

Organism

Setaria italica

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MDADPSRQVR VRFVTKMPPP LRAPPAAIAV PADLSRMGLS EIVNSLLAAA EPDHKAQPFD 60
FLVDGELVRL PLQQFLLAKG ITAERVLELE YVKAVAPRKQ DKPCPHDDWV SAVDGSNPSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGCCG ACCCCTCGCG CCAGGTGCGC GTGCGCTTCG TCACCAAGAT GCCGCCCCCA 60
CTGCGTGCGC CGCCCGCCGC CATCGCCGTC CCCGCCGACC TCTCCCGCAT GGGCCTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

KEGG

sita:101765488

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001997	Ailuropoda melanoleuca	36.06	5.00e-55	207.00
IUUC-Apl-003981	Anas platyrhynchos	35.45	2.00e-57	215.00
IUUC-Aca-004370	Anolis carolinensis	34.87	8.00e-62	230.00
IUUC-Ame-011432	Astyanax mexicanus	35.90	3.00e-64	238.00
IUUC-Bta-012829	Bos taurus	35.55	2.00e-55	209.00
IUUC-Cja-019468	Callithrix jacchus	36.06	1.00e-53	202.00
IUUC-Cfa-020471	Canis familiaris	35.38	9.00e-54	203.00
IUUC-Cpo-022260	Cavia porcellus	37.34	3.00e-56	211.00
IUUC-Csa-023989	Chlorocebus sabaeus	35.81	1.00e-53	202.00
IUUC-Cho-024426	Choloepus hoffmanni	33.01	3.00e-39	155.00
IUUC-Cin-025789	Ciona intestinalis	32.75	3.00e-52	198.00
IUUC-Dre-027907	Danio rerio	35.64	3.00e-64	238.00
IUUC-Dno-029225	Dasypus novemcinctus	35.81	2.00e-55	209.00
IUUC-Ete-032247	Echinops telfairi	33.50	1.00e-47	183.00
IUUC-Eca-034285	Equus caballus	35.55	2.00e-54	205.00
IUUC-Eeu-035322	Erinaceus europaeus	31.20	6.00e-45	174.00
IUUC-Fca-036114	Felis catus	35.81	6.00e-55	207.00
IUUC-Fal-036891	Ficedula albicollis	36.09	8.00e-51	193.00
IUUC-Gmo-039040	Gadus morhua	35.20	2.00e-64	238.00
IUUC-Ggr-040093	Gaeumannomyces graminis	24.63	8.00e-23	100.00
IUUC-Gga-040610	Gallus gallus	36.64	5.00e-61	227.00
IUUC-Gac-042117	Gasterosteus aculeatus	34.43	1.00e-62	232.00
IUUC-Ggo-045179	Gorilla gorilla	35.55	5.00e-53	201.00
IUUC-Hsa-046114	Homo sapiens	35.81	2.00e-53	202.00
IUUC-Itr-048275	Ictidomys tridecemlineatus	36.06	2.00e-55	209.00
IUUC-Kpa-049304	Komagataella pastoris	28.11	7.00e-42	164.00
IUUC-Lch-050655	Latimeria chalumnae	32.28	3.00e-40	158.00
IUUC-Loc-052868	Lepisosteus oculatus	36.02	3.00e-63	234.00
IUUC-Laf-053993	Loxodonta africana	35.55	3.00e-55	208.00
IUUC-Mcc-055128	Macaca mulatta	29.65	1.00e-30	126.00
IUUC-Meu-056501	Macropus eugenii	35.59	1.00e-48	186.00
IUUC-Mor-057114	Magnaporthe oryzae	28.23	3.00e-36	145.00
IUUC-Mpo-057463	Magnaporthe poae	32.64	1.00e-15	75.90
IUUC-Mla-059107	Melampsora laricipopulina	27.82	1.00e-34	140.00
IUUC-Mga-059745	Meleagris gallopavo	36.20	2.00e-60	225.00
IUUC-Mvi-060362	Microbotryum violaceum	24.60	1.00e-25	110.00
IUUC-Mdo-062257	Monodelphis domestica	36.90	5.00e-62	231.00
IUUC-Mmu-063546	Mus musculus	34.62	9.00e-55	206.00
IUUC-Mpu-066284	Mustela putorius furo	35.81	3.00e-55	209.00
IUUC-Mlu-067241	Myotis lucifugus	36.32	8.00e-56	210.00
IUUC-Ncr-068719	Neurospora crassa	28.74	1.00e-29	124.00
IUUC-Nle-068981	Nomascus leucogenys	36.06	1.00e-52	199.00
IUUC-Opr-071218	Ochotona princeps	33.60	2.00e-50	192.00
IUUC-Ont-071646	Oreochromis niloticus	35.55	5.00e-57	214.00
IUUC-Oan-073453	Ornithorhynchus anatinus	36.20	5.00e-64	237.00
IUUC-Ocu-074008	Oryctolagus cuniculus	36.32	4.00e-56	211.00
IUUC-Ola-087420	Oryzias latipes	34.19	1.00e-64	239.00
IUUC-Oga-088264	Otolemur garnettii	35.29	2.00e-52	199.00
IUUC-Oar-089335	Ovis aries	35.81	5.00e-56	211.00
IUUC-Ptr-091320	Pan troglodytes	35.81	2.00e-53	202.00
IUUC-Pan-092833	Papio anubis	35.55	2.00e-53	202.00
IUUC-Psi-093504	Pelodiscus sinensis	34.86	1.00e-55	209.00
IUUC-Pma-094189	Petromyzon marinus	34.12	7.00e-59	220.00
IUUC-Pfo-096337	Poecilia formosa	35.48	1.00e-63	236.00
IUUC-Pab-097571	Pongo abelii	35.55	3.00e-53	201.00
IUUC-Pca-100394	Procavia capensis	33.50	6.00e-45	174.00
IUUC-Ppe-101848	Prunus persica	59.58	1.00e-157	548.00
IUUC-Rno-105114	Rattus norvegicus	34.62	8.00e-54	203.00
IUUC-Sha-107122	Sarcophilus harrisii	37.34	7.00e-61	227.00
IUUC-Sar-113596	Sorex araneus	32.00	3.00e-42	165.00
IUUC-Sre-115002	Sporisorium reilianum	29.58	6.00e-18	84.70
IUUC-Ssc-116066	Sus scrofa	35.81	2.00e-55	208.00
IUUC-Tgu-117048	Taeniopygia guttata	36.15	4.00e-57	214.00
IUUC-Tni-119820	Tetraodon nigroviridis	36.06	3.00e-59	221.00
IUUC-Tre-121947	Trichoderma reesei	27.25	5.00e-32	131.00
IUUC-Tvi-122481	Trichoderma virens	27.25	5.00e-32	131.00
IUUC-Tbe-127736	Tupaia belangeri	38.46	1.00e-21	96.70
IUUC-Ttr-129041	Tursiops truncatus	30.77	3.00e-38	151.00
IUUC-Vpa-130260	Vicugna pacos	35.81	2.00e-55	209.00
IUUC-Xtr-132083	Xenopus tropicalis	37.44	2.00e-59	222.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence