iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035492

Ensembl Protein ID

ENSFCAP00000022716.1

UniProt Accession

M3X7W4; M3X7W4_FELCA

Genbank Protein ID

ENSFCAP00000022716

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02126099

Gene Name

TRIM62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000029468.1	ENSFCAT00000028578.1	ENSFCAP00000022716.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.30e-07	30.3	6	75
E3 activity/RING/RING	5.50e-08	33.2	11	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwl....asggktcPvtrqplteedlvPnltlrrliqaw 68
            +e+lC+I l + +dPv l + + + r++I ++     a+g + cP +r++++e  l P+l l ++++++
   Q: 6    KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWvrqeAQGARDCPECRRTFAEPALAPSLKLANIVERY 75
           689***************************9888455444444*******************99999887 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p++l+C H f++ C+ ++w+ +   ++++  CP Cr
   Q: 11   CSICLSIYQD-PVSLGCEHYFCRRCItEHWVRQE--AQGARDCPECR 54
           **********.*******************5555..**********8 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MACSLKDELL CSICLSIYQD PVSLGCEHYF CRRCITEHWV RQEAQGARDC PECRRTFAEP 60
ALAPSLKLAN IVERYSAFPL DAILESKGSG KECQQYGRLP LSCASLSHKT CLEERPPLIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGCA GCCTCAAGGA CGAGCTGCTC TGCTCCATCT GTCTGAGCAT CTACCAGGAC 60
CCGGTGAGCC TGGGCTGCGA GCACTACTTC TGCCGCCGCT GCATCACCGA GCACTGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0032897--P:negative regulation of viral transcription
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002199	Ailuropoda melanoleuca	91.00	0.00e+00	863.00
IUUC-Apl-003767	Anas platyrhynchos	82.39	0.00e+00	723.00
IUUC-Aca-004412	Anolis carolinensis	81.42	0.00e+00	789.00
IUUC-Ame-010927	Astyanax mexicanus	77.36	0.00e+00	769.00
IUUC-Bta-012927	Bos taurus	90.79	0.00e+00	862.00
IUUC-Cja-019317	Callithrix jacchus	84.52	0.00e+00	773.00
IUUC-Cfa-020292	Canis familiaris	99.13	0.00e+00	702.00
IUUC-Cpo-022274	Cavia porcellus	100.00	0.00e+00	704.00
IUUC-Csa-023042	Chlorocebus sabaeus	91.00	0.00e+00	863.00
IUUC-Dre-028493	Danio rerio	76.52	0.00e+00	763.00
IUUC-Dno-030029	Dasypus novemcinctus	86.40	0.00e+00	803.00
IUUC-Dor-031051	Dipodomys ordii	90.57	0.00e+00	830.00
IUUC-Ete-032752	Echinops telfairi	98.35	8.00e-109	387.00
IUUC-Eca-033898	Equus caballus	79.26	0.00e+00	811.00
IUUC-Eeu-034659	Erinaceus europaeus	100.00	1.00e-84	306.00
IUUC-Fal-036867	Ficedula albicollis	82.02	0.00e+00	778.00
IUUC-Gmo-038916	Gadus morhua	76.52	0.00e+00	739.00
IUUC-Gga-040360	Gallus gallus	84.52	0.00e+00	804.00
IUUC-Gac-041871	Gasterosteus aculeatus	77.15	0.00e+00	770.00
IUUC-Ggo-044411	Gorilla gorilla	84.73	0.00e+00	783.00
IUUC-Hsa-047025	Homo sapiens	90.97	0.00e+00	886.00
IUUC-Itr-047905	Ictidomys tridecemlineatus	91.00	0.00e+00	863.00
IUUC-Loc-052114	Lepisosteus oculatus	78.83	0.00e+00	784.00
IUUC-Laf-054359	Loxodonta africana	96.65	0.00e+00	644.00
IUUC-Mcc-055563	Macaca mulatta	91.00	0.00e+00	863.00
IUUC-Meu-056027	Macropus eugenii	68.28	0.00e+00	633.00
IUUC-Mga-060146	Meleagris gallopavo	68.00	7.00e-53	199.00
IUUC-Mmr-060822	Microcebus murinus	91.00	0.00e+00	863.00
IUUC-Mdo-062117	Monodelphis domestica	69.60	2.00e-159	555.00
IUUC-Mmu-064086	Mus musculus	90.79	0.00e+00	862.00
IUUC-Mpu-066378	Mustela putorius furo	91.00	0.00e+00	863.00
IUUC-Mlu-067155	Myotis lucifugus	90.25	0.00e+00	870.00
IUUC-Nle-069464	Nomascus leucogenys	90.59	0.00e+00	860.00
IUUC-Opr-071058	Ochotona princeps	98.64	2.00e-133	469.00
IUUC-Ont-071253	Oreochromis niloticus	69.67	0.00e+00	666.00
IUUC-Oan-073614	Ornithorhynchus anatinus	93.67	3.00e-91	326.00
IUUC-Ola-086794	Oryzias latipes	77.36	0.00e+00	767.00
IUUC-Oga-088889	Otolemur garnettii	90.38	0.00e+00	860.00
IUUC-Oar-089203	Ovis aries	88.81	0.00e+00	768.00
IUUC-Ptr-090795	Pan troglodytes	91.18	0.00e+00	888.00
IUUC-Pfo-096942	Poecilia formosa	76.73	0.00e+00	759.00
IUUC-Pab-097936	Pongo abelii	83.77	1.00e-176	611.00
IUUC-Pca-100397	Procavia capensis	89.54	0.00e+00	852.00
IUUC-Ppe-101916	Prunus persica	35.71	7.00e-10	59.70
IUUC-Pva-102293	Pteropus vampyrus	99.41	0.00e+00	689.00
IUUC-Rno-105551	Rattus norvegicus	90.59	0.00e+00	858.00
IUUC-Sre-115193	Sporisorium reilianum	45.83	2.00e-07	50.80
IUUC-Ssc-115983	Sus scrofa	91.00	0.00e+00	863.00
IUUC-Tgu-117279	Taeniopygia guttata	68.67	9.00e-166	576.00
IUUC-Tru-118238	Takifugu rubripes	76.94	0.00e+00	763.00
IUUC-Tni-119788	Tetraodon nigroviridis	55.44	1.00e-134	473.00
IUUC-Xtr-132768	Xenopus tropicalis	69.48	0.00e+00	653.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence