iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000012067.2	ENSPPYT00000033999.1	ENSPPYP00000024735.1
ENSPPYG00000012067.2	ENSPPYT00000014003.1	ENSPPYP00000013454.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.50e-44	145.6	192	222
UBD/Beta-Prp	1.80e-59	201.4	13	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH++ v++laf ++  +l+s+sdD t+++W+
   Q: 192  GHESTVWSLAFdPSgQRLASCSDDRTVRIWR 222
           8***********6669**************8 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrsl.sgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtl 90
           +h++s++  +++ p ++lla+ + d++i++w ++  +    + l +gh+ +v+ v +sp g++l+++s D+t ++w  + ++++cv tl
   Q: 13   AHPDSRCWFLAWNPTGTLLASCGGDRRIRIWGTEGDSWicKSVLsEGHQRTVRKVAWSPCGNYLASASFDATTCIWkkNQDDFECVTTL 101
           688999999999*********************9877654566689******************************99999******** PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk..llrtl 175
           +ghe++v s+++ psg+ l++ s+d+ + vw+++++ ++e   +l+ h++ v +vv+hp++ ll+s+s+D tv+l++ + ++  +  tl
   Q: 102  EGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECvsVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDwvCCATL 190
           *********************************9987776566*********************************99777544999** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklw 207
           +g h++ v sl+fd++g++l+s+s+d+tv++w
   Q: 191  EG-HESTVWSLAFDPSGQRLASCSDDRTVRIW 221
           *9.***************************** PP

Organism

Pongo abelii

Functional Description
(View)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

Protein Sequence
(Fasta)

MKDSLVLLGR VPAHPDSRCW FLAWNPTGTL LASCGGDRRI RIWGTEGDSW ICKSVLSEGH 60
QRTVRKVAWS PCGNYLASAS FDATTCIWKK NQDDFECVTT LEGHENEVKS VAWAPSGNLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAAACAGA GCCACCTGCT GGGCATGAAC ACCAGGCAGT TATGGGGCCG TTTCCTTCAA 60
CCAAGTGTCT GGTCCCTGGC TATCTCTGCT TCAGCCAGAA CACATTCTGT CCCTCACCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0071817--C:MMXD complex
GO:0007059--P:chromosome segregation
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	42.49	1.00e-66	248.00
IUUC-Aml-001317	Ailuropoda melanoleuca	96.17	0.00e+00	626.00
IUUC-Atr-003029	Amborella trichopoda	52.06	4.00e-94	337.00
IUUC-Apl-004042	Anas platyrhynchos	75.76	3.00e-54	203.00
IUUC-Aly-006458	Arabidopsis lyrata	48.26	1.00e-85	309.00
IUUC-Ath-006671	Arabidopsis thaliana	48.26	1.00e-85	309.00
IUUC-Ago-007820	Ashbya gossypii	40.41	5.00e-60	224.00
IUUC-Acl-008042	Aspergillus clavatus	31.57	2.00e-48	186.00
IUUC-Afl-008639	Aspergillus flavus	32.14	1.00e-50	194.00
IUUC-Afu-008899	Aspergillus fumigatus	35.51	3.00e-47	182.00
IUUC-Ani-009453	Aspergillus nidulans	32.38	2.00e-49	189.00
IUUC-Ang-009758	Aspergillus niger	34.41	2.00e-49	189.00
IUUC-Aor-010212	Aspergillus oryzae	32.14	1.00e-50	194.00
IUUC-Ate-010314	Aspergillus terreus	32.37	8.00e-51	194.00
IUUC-Ame-010676	Astyanax mexicanus	76.95	3.00e-155	540.00
IUUC-Bgr-012095	Blumeria graminis	30.22	6.00e-36	144.00
IUUC-Bta-012884	Bos taurus	92.92	2.00e-174	604.00
IUUC-Bci-013622	Botrytis cinerea	32.28	1.00e-35	143.00
IUUC-Bdi-014614	Brachypodium distachyon	48.37	1.00e-85	309.00
IUUC-Bol-016439	Brassica oleracea	49.12	8.00e-83	300.00
IUUC-Bra-016830	Brassica rapa	48.08	1.00e-81	296.00
IUUC-Cel-018709	Caenorhabditis elegans	39.76	6.00e-61	227.00
IUUC-Cja-019822	Callithrix jacchus	97.94	0.00e+00	638.00
IUUC-Cfa-020823	Canis familiaris	97.35	0.00e+00	632.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	47.26	6.00e-81	294.00
IUUC-Csa-023754	Chlorocebus sabaeus	99.41	0.00e+00	645.00
IUUC-Cin-025395	Ciona intestinalis	57.01	4.00e-114	404.00
IUUC-Csv-025943	Ciona savignyi	54.95	6.00e-110	390.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	33.33	2.00e-34	139.00
IUUC-Cne-026939	Cryptococcus neoformans	32.59	8.00e-49	187.00
IUUC-Cme-027239	Cyanidioschyzon merolae	40.93	8.00e-45	174.00
IUUC-Dre-028172	Danio rerio	76.35	4.00e-153	533.00
IUUC-Dno-029472	Dasypus novemcinctus	95.22	2.00e-151	528.00
IUUC-Dor-031134	Dipodomys ordii	85.25	2.00e-152	531.00
IUUC-Dse-031535	Dothistroma septosporum	30.09	8.00e-45	174.00
IUUC-Dme-032020	Drosophila melanogaster	58.79	1.00e-115	409.00
IUUC-Eca-033700	Equus caballus	97.35	0.00e+00	634.00
IUUC-Eeu-035010	Erinaceus europaeus	93.81	4.00e-175	607.00
IUUC-Fca-036309	Felis catus	88.24	8.00e-170	589.00
IUUC-Fal-037243	Ficedula albicollis	73.83	2.00e-85	308.00
IUUC-Fox-038058	Fusarium oxysporum	32.82	8.00e-42	165.00
IUUC-Fso-038459	Fusarium solani	35.10	4.00e-37	149.00
IUUC-Gmo-039375	Gadus morhua	75.52	7.00e-139	486.00
IUUC-Ggr-040002	Gaeumannomyces graminis	35.77	4.00e-41	162.00
IUUC-Gga-040294	Gallus gallus	82.77	2.00e-127	448.00
IUUC-Gac-042499	Gasterosteus aculeatus	74.48	7.00e-137	479.00
IUUC-Gma-043543	Glycine max	48.52	2.00e-87	315.00
IUUC-Ggo-045181	Gorilla gorilla	99.41	0.00e+00	645.00
IUUC-Hsa-046528	Homo sapiens	99.41	0.00e+00	645.00
IUUC-Hvu-047341	Hordeum vulgare	56.91	2.00e-55	208.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	97.35	0.00e+00	633.00
IUUC-Kpa-049353	Komagataella pastoris	37.22	1.00e-56	213.00
IUUC-Lch-049763	Latimeria chalumnae	80.24	7.00e-159	552.00
IUUC-Lpe-051500	Leersia perrieri	44.32	2.00e-82	299.00
IUUC-Loc-052021	Lepisosteus oculatus	80.24	2.00e-151	528.00
IUUC-Lma-053331	Leptosphaeria maculans	34.75	3.00e-53	203.00
IUUC-Laf-054558	Loxodonta africana	94.69	8.00e-178	615.00
IUUC-Mcc-055374	Macaca mulatta	99.12	0.00e+00	643.00
IUUC-Meu-056042	Macropus eugenii	77.85	2.00e-113	401.00
IUUC-Mor-057187	Magnaporthe oryzae	33.89	6.00e-39	154.00
IUUC-Mtr-058072	Medicago truncatula	48.66	3.00e-86	311.00
IUUC-Mla-059108	Melampsora laricipopulina	31.36	1.00e-50	194.00
IUUC-Mga-059370	Meleagris gallopavo	63.93	4.00e-99	353.00
IUUC-Mvi-060495	Microbotryum violaceum	36.65	4.00e-57	215.00
IUUC-Mmr-060902	Microcebus murinus	97.05	0.00e+00	629.00
IUUC-Mdo-062510	Monodelphis domestica	92.92	1.00e-169	588.00
IUUC-Mmu-063575	Mus musculus	94.69	1.00e-178	618.00
IUUC-Mac-065322	Musa acuminata	50.30	9.00e-91	326.00
IUUC-Mpu-065925	Mustela putorius furo	96.17	1.00e-180	625.00
IUUC-Mlu-067755	Myotis lucifugus	96.76	0.00e+00	627.00
IUUC-Nfi-068327	Neosartorya fischeri	31.22	5.00e-47	181.00
IUUC-Ncr-068845	Neurospora crassa	32.30	8.00e-31	127.00
IUUC-Nle-069406	Nomascus leucogenys	97.64	0.00e+00	632.00
IUUC-Opr-070416	Ochotona princeps	98.16	3.00e-79	288.00
IUUC-Ont-071936	Oreochromis niloticus	75.37	1.00e-140	492.00
IUUC-Oan-073452	Ornithorhynchus anatinus	92.68	2.00e-75	274.00
IUUC-Ocu-074791	Oryctolagus cuniculus	95.28	2.00e-179	620.00
IUUC-Oba-075636	Oryza barthii	49.11	1.00e-88	319.00
IUUC-Obr-076742	Oryza brachyantha	48.42	3.00e-77	281.00
IUUC-Ogl-077766	Oryza glaberrima	49.11	1.00e-88	319.00
IUUC-Ogu-079039	Oryza glumaepatula	49.11	6.00e-89	320.00
IUUC-Oin-079315	Oryza indica	49.14	6.00e-78	284.00
IUUC-Olo-080669	Oryza longistaminata	43.60	1.00e-80	293.00
IUUC-Ome-081490	Oryza meridionalis	49.11	9.00e-89	320.00
IUUC-Oni-082572	Oryza nivara	49.11	1.00e-88	319.00
IUUC-Opu-083732	Oryza punctata	49.25	9.00e-89	320.00
IUUC-Oru-084763	Oryza rufipogon	49.11	1.00e-88	319.00
IUUC-Osa-085372	Oryza sativa	49.11	1.00e-88	319.00
IUUC-Ola-087379	Oryzias latipes	73.24	2.00e-136	478.00
IUUC-Olu-087801	Ostreococcus lucimarinus	35.22	3.00e-44	172.00
IUUC-Oga-089076	Otolemur garnettii	96.46	0.00e+00	626.00
IUUC-Oar-090022	Ovis aries	92.63	2.00e-173	601.00
IUUC-Ptr-090809	Pan troglodytes	99.41	0.00e+00	645.00
IUUC-Pan-091685	Papio anubis	99.41	0.00e+00	652.00
IUUC-Psi-093046	Pelodiscus sinensis	87.83	1.00e-166	578.00
IUUC-Pma-094181	Petromyzon marinus	63.50	1.00e-129	456.00
IUUC-Pno-094882	Phaeosphaeria nodorum	35.19	4.00e-54	205.00
IUUC-Ppa-095172	Physcomitrella patens	47.38	1.00e-83	302.00
IUUC-Pfo-096396	Poecilia formosa	71.81	5.00e-137	480.00
IUUC-Pop-100016	Populus trichocarpa	51.49	2.00e-90	325.00
IUUC-Pca-101048	Procavia capensis	94.99	4.00e-178	617.00
IUUC-Ppe-102050	Prunus persica	46.70	2.00e-86	312.00
IUUC-Pva-103117	Pteropus vampyrus	95.58	1.00e-179	622.00
IUUC-Pgr-103307	Puccinia graminis	34.25	3.00e-56	212.00
IUUC-Ptt-103938	Puccinia triticina	37.72	4.00e-48	184.00
IUUC-Pte-104315	Pyrenophora teres	33.81	1.00e-54	206.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	33.09	2.00e-53	203.00
IUUC-Rno-105523	Rattus norvegicus	94.40	2.00e-178	617.00
IUUC-Sce-106297	Saccharomyces cerevisiae	42.09	2.00e-65	242.00
IUUC-Sha-106981	Sarcophilus harrisii	91.81	1.00e-140	492.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	39.24	2.00e-56	213.00
IUUC-Spo-108214	Schizosaccharomyces pombe	40.00	3.00e-57	216.00
IUUC-Smo-109034	Selaginella moellendorffii	45.05	9.00e-80	290.00
IUUC-Sit-110663	Setaria italica	50.00	7.00e-90	323.00
IUUC-Sly-110898	Solanum lycopersicum	48.10	6.00e-82	297.00
IUUC-Stu-112647	Solanum tuberosum	51.14	5.00e-69	253.00
IUUC-Sbi-114288	Sorghum bicolor	47.65	2.00e-85	308.00
IUUC-Sre-115065	Sporisorium reilianum	42.93	2.00e-74	273.00
IUUC-Ssc-115960	Sus scrofa	89.02	8.00e-177	612.00
IUUC-Tru-118382	Takifugu rubripes	70.62	1.00e-144	505.00
IUUC-Tsy-119585	Tarsius syrichta	88.50	1.00e-161	561.00
IUUC-Tni-120133	Tetraodon nigroviridis	74.24	1.00e-140	492.00
IUUC-Tca-121167	Theobroma cacao	49.11	4.00e-81	294.00
IUUC-Tre-122119	Trichoderma reesei	28.87	4.00e-38	152.00
IUUC-Tae-125748	Triticum aestivum	47.94	3.00e-82	298.00
IUUC-Tur-126682	Triticum urartu	48.33	2.00e-67	248.00
IUUC-Tme-127095	Tuber melanosporum	36.22	7.00e-60	224.00
IUUC-Tbe-128004	Tupaia belangeri	96.46	0.00e+00	628.00
IUUC-Ttr-129284	Tursiops truncatus	90.94	6.00e-168	583.00
IUUC-Uma-129527	Ustilago maydis	42.51	1.00e-73	270.00
IUUC-Vda-129854	Verticillium dahliae	31.52	6.00e-36	144.00
IUUC-Vpa-130681	Vicugna pacos	97.41	7.00e-50	190.00
IUUC-Vvi-131004	Vitis vinifera	53.61	5.00e-88	317.00
IUUC-Xtr-131928	Xenopus tropicalis	81.01	3.00e-153	533.00
IUUC-Xma-134290	Xiphophorus maculatus	70.62	2.00e-133	468.00
IUUC-Yli-134364	Yarrowia lipolytica	43.57	1.00e-67	249.00
IUUC-Zma-135658	Zea mays	49.11	2.00e-86	312.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence