iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000005006.5	ENSGALT00000065789.1	ENSGALP00000055468.1
ENSGALG00000005006.5	ENSGALT00000008017.5	ENSGALP00000008003.5
ENSGALG00000005006.5	ENSGALT00000029547.3	ENSGALP00000028895.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	8.40e-138	460.4	9	421

Active Site

Position(s)	Description	Evidence
175	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 8    wGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahees 96
           +G+e  e++ +a+ l+vGagg+GcEllK Lvl+G+++i v+D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p  n+ a+++s
   Q: 9    LGSELAEAVAQARLLVVGAGGIGCELLKDLVLTGFSNIDVIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPEANIIAYHDS 97
           79*************************************************************************************** PP
   S: 97   iteleeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaeh 185
           i++++++++Ff++f++V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv+vi kg+tecy+c+++p+qkt+P+ct+++tp+++ h
   Q: 98   IMNPDYNVEFFRQFTLVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTVIKKGVTECYECHPKPTQKTFPGCTIRNTPSEPIH 186
           ***************************************************************************************** PP
   S: 186  tiewa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspf 272
           +i+wa +lfn+l++ee++++ev++  d++++e+++++ ++e+++++++++ e++++++k++ak+t ++ +k ++k f++di++  ++++
   Q: 187  CIVWAkYLFNQLFGEEDADQEVSP--DRADPEAAWEPAEAEARARASNEDGEIKRVSTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDK 273
           ************************..799************************************************************ PP
   S: 273  wv................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaa 340
           ++                + +++ +++++ ++v+kd++v++++++     +++++++l+++ek +g    el ++kdd+sa+d+vt+aa
   Q: 274  LWrkrkppvpldwaevqnQEKNVPDQQNESSSVLKDQQVLDVKSYahlfsKSVETLRLHLAEKGDGA---ELIWDKDDPSAMDFVTSAA 359
           *****************9999999************************99999*************9...68***************** PP
   S: 341  nlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           nlr++ +++++  ++++ik++agniipaiattna+++Gl+++E +K++sgk ++++++fl+++
   Q: 360  NLRMHVFSMNM-KSRFDIKSMAGNIIPAIATTNAIIAGLIVLEGLKILSGKIDQCRTIFLNKQ 421
           ***********.***********************************************9965 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MSVPVSGPLG SELAEAVAQA RLLVVGAGGI GCELLKDLVL TGFSNIDVID LDTIDVSNLN 60
RQFLFQKKHV GRSKAQVAKE SVLQFYPEAN IIAYHDSIMN PDYNVEFFRQ FTLVMNALDN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGCGGCGC TGCCATGGCG GCGGCTGCGC CGCCGGTGCT GCTGGGCCTC CGCGACGCCG 60
CCATGGTGGG GCCGTGCCGG GGCGGCGGGG AGCCCCCGGG CTGGGCCACC AACAAGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	40.07	8.00e-106	377.00
IUUC-Aml-001662	Ailuropoda melanoleuca	89.03	0.00e+00	1092.00
IUUC-Atr-002636	Amborella trichopoda	40.36	2.00e-115	409.00
IUUC-Apl-003369	Anas platyrhynchos	97.46	0.00e+00	1119.00
IUUC-Aca-004490	Anolis carolinensis	83.66	0.00e+00	927.00
IUUC-Aly-006359	Arabidopsis lyrata	41.03	9.00e-102	364.00
IUUC-Ath-007667	Arabidopsis thaliana	41.62	1.00e-104	373.00
IUUC-Ago-007844	Ashbya gossypii	37.48	7.00e-82	297.00
IUUC-Acl-008270	Aspergillus clavatus	42.07	5.00e-106	378.00
IUUC-Afl-008674	Aspergillus flavus	41.04	4.00e-111	395.00
IUUC-Afu-008883	Aspergillus fumigatus	41.74	7.00e-107	380.00
IUUC-Ani-009500	Aspergillus nidulans	43.39	1.00e-114	406.00
IUUC-Ang-009535	Aspergillus niger	42.00	9.00e-111	394.00
IUUC-Aor-010223	Aspergillus oryzae	40.89	4.00e-111	395.00
IUUC-Ate-010282	Aspergillus terreus	44.13	2.00e-88	319.00
IUUC-Ame-011736	Astyanax mexicanus	76.53	0.00e+00	956.00
IUUC-Bgr-012166	Blumeria graminis	43.11	4.00e-100	358.00
IUUC-Bta-012589	Bos taurus	89.20	0.00e+00	1100.00
IUUC-Bci-013802	Botrytis cinerea	43.51	5.00e-103	368.00
IUUC-Bdi-014697	Brachypodium distachyon	37.70	6.00e-108	384.00
IUUC-Bol-016315	Brassica oleracea	41.55	3.00e-107	382.00
IUUC-Bra-017009	Brassica rapa	38.76	4.00e-107	382.00
IUUC-Cel-018708	Caenorhabditis elegans	44.29	9.00e-131	460.00
IUUC-Cja-019120	Callithrix jacchus	89.20	0.00e+00	1090.00
IUUC-Cfa-021061	Canis familiaris	88.87	0.00e+00	1097.00
IUUC-Cpo-021842	Cavia porcellus	88.87	0.00e+00	1089.00
IUUC-Csa-024104	Chlorocebus sabaeus	87.91	0.00e+00	1066.00
IUUC-Cho-024332	Choloepus hoffmanni	82.38	0.00e+00	814.00
IUUC-Cin-025363	Ciona intestinalis	60.84	0.00e+00	674.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.72	5.00e-100	358.00
IUUC-Cne-026888	Cryptococcus neoformans	40.50	1.00e-76	280.00
IUUC-Cme-027315	Cyanidioschyzon merolae	33.33	6.00e-58	218.00
IUUC-Dre-028420	Danio rerio	76.42	0.00e+00	925.00
IUUC-Dno-030041	Dasypus novemcinctus	88.89	0.00e+00	1090.00
IUUC-Dor-031039	Dipodomys ordii	74.94	2.00e-168	585.00
IUUC-Dse-031504	Dothistroma septosporum	44.72	1.00e-94	340.00
IUUC-Dme-031771	Drosophila melanogaster	48.63	9.00e-146	510.00
IUUC-Ete-033037	Echinops telfairi	82.82	0.00e+00	977.00
IUUC-Eca-033774	Equus caballus	89.39	0.00e+00	1070.00
IUUC-Eeu-035074	Erinaceus europaeus	87.45	0.00e+00	853.00
IUUC-Fca-036508	Felis catus	89.39	0.00e+00	1072.00
IUUC-Fal-036813	Ficedula albicollis	91.36	0.00e+00	1076.00
IUUC-Fox-038056	Fusarium oxysporum	43.71	1.00e-105	377.00
IUUC-Fso-038223	Fusarium solani	42.96	2.00e-105	375.00
IUUC-Gmo-038526	Gadus morhua	74.29	0.00e+00	860.00
IUUC-Ggr-039767	Gaeumannomyces graminis	43.65	3.00e-101	362.00
IUUC-Gac-041437	Gasterosteus aculeatus	72.63	0.00e+00	894.00
IUUC-Gma-044072	Glycine max	37.23	7.00e-112	397.00
IUUC-Ggo-045358	Gorilla gorilla	84.90	0.00e+00	1018.00
IUUC-Hsa-046068	Homo sapiens	88.05	0.00e+00	1071.00
IUUC-Hvu-047646	Hordeum vulgare	37.24	1.00e-105	377.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	88.73	0.00e+00	1086.00
IUUC-Lch-049565	Latimeria chalumnae	81.22	0.00e+00	1011.00
IUUC-Lpe-050884	Leersia perrieri	40.56	9.00e-107	380.00
IUUC-Loc-052493	Lepisosteus oculatus	79.49	0.00e+00	976.00
IUUC-Lma-053117	Leptosphaeria maculans	43.94	2.00e-101	362.00
IUUC-Laf-054518	Loxodonta africana	86.27	0.00e+00	1070.00
IUUC-Mcc-055334	Macaca mulatta	88.05	0.00e+00	1071.00
IUUC-Mor-057137	Magnaporthe oryzae	45.16	6.00e-93	335.00
IUUC-Mpo-057449	Magnaporthe poae	40.70	2.00e-103	369.00
IUUC-Mtr-058045	Medicago truncatula	38.87	2.00e-113	403.00
IUUC-Mla-058864	Melampsora laricipopulina	47.10	5.00e-97	348.00
IUUC-Mga-059422	Meleagris gallopavo	92.46	0.00e+00	1034.00
IUUC-Mvi-060536	Microbotryum violaceum	40.34	8.00e-89	321.00
IUUC-Mmr-061161	Microcebus murinus	87.96	0.00e+00	1092.00
IUUC-Mdo-061802	Monodelphis domestica	89.84	0.00e+00	1092.00
IUUC-Mmu-064357	Mus musculus	86.79	0.00e+00	1105.00
IUUC-Mac-065475	Musa acuminata	40.28	7.00e-110	390.00
IUUC-Mpu-066895	Mustela putorius furo	89.03	0.00e+00	1096.00
IUUC-Mlu-067862	Myotis lucifugus	89.23	0.00e+00	1106.00
IUUC-Nfi-068385	Neosartorya fischeri	42.88	1.00e-107	383.00
IUUC-Ncr-068885	Neurospora crassa	44.66	2.00e-106	379.00
IUUC-Nle-069524	Nomascus leucogenys	87.40	0.00e+00	1056.00
IUUC-Opr-071038	Ochotona princeps	88.12	0.00e+00	1125.00
IUUC-Ont-071719	Oreochromis niloticus	76.30	0.00e+00	947.00
IUUC-Oan-072877	Ornithorhynchus anatinus	88.01	0.00e+00	981.00
IUUC-Ocu-074080	Oryctolagus cuniculus	88.38	0.00e+00	1082.00
IUUC-Oba-075936	Oryza barthii	37.90	1.00e-106	380.00
IUUC-Obr-076841	Oryza brachyantha	39.15	4.00e-109	388.00
IUUC-Ogl-077686	Oryza glaberrima	37.96	2.00e-108	385.00
IUUC-Ogu-078597	Oryza glumaepatula	36.96	1.00e-103	370.00
IUUC-Oin-079791	Oryza indica	37.90	1.00e-106	380.00
IUUC-Olo-081009	Oryza longistaminata	37.90	9.00e-107	380.00
IUUC-Ome-081327	Oryza meridionalis	35.69	1.00e-101	363.00
IUUC-Oni-082334	Oryza nivara	37.15	2.00e-104	372.00
IUUC-Opu-083447	Oryza punctata	37.88	1.00e-108	387.00
IUUC-Oru-084977	Oryza rufipogon	37.90	8.00e-107	380.00
IUUC-Osa-086160	Oryza sativa	44.12	2.00e-94	338.00
IUUC-Ola-087415	Oryzias latipes	76.55	0.00e+00	939.00
IUUC-Olu-087850	Ostreococcus lucimarinus	40.52	1.00e-101	363.00
IUUC-Oga-088434	Otolemur garnettii	89.20	0.00e+00	1097.00
IUUC-Oar-089872	Ovis aries	89.41	0.00e+00	1066.00
IUUC-Ptr-091212	Pan troglodytes	88.05	0.00e+00	1071.00
IUUC-Pan-092708	Papio anubis	94.78	5.00e-123	434.00
IUUC-Psi-093703	Pelodiscus sinensis	93.57	0.00e+00	1089.00
IUUC-Pno-094953	Phaeosphaeria nodorum	45.48	9.00e-104	370.00
IUUC-Ppa-095963	Physcomitrella patens	42.81	1.00e-108	386.00
IUUC-Pfo-097515	Poecilia formosa	74.88	0.00e+00	901.00
IUUC-Pab-097951	Pongo abelii	87.32	0.00e+00	939.00
IUUC-Pop-099703	Populus trichocarpa	36.52	3.00e-95	342.00
IUUC-Pca-100426	Procavia capensis	86.74	0.00e+00	1069.00
IUUC-Ppe-101152	Prunus persica	39.32	1.00e-108	386.00
IUUC-Pva-102792	Pteropus vampyrus	85.34	0.00e+00	1036.00
IUUC-Pgr-103592	Puccinia graminis	41.62	3.00e-99	355.00
IUUC-Ptt-103805	Puccinia triticina	40.34	1.00e-84	307.00
IUUC-Pte-104215	Pyrenophora teres	44.54	2.00e-111	395.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	39.02	1.00e-110	393.00
IUUC-Rno-106117	Rattus norvegicus	86.66	0.00e+00	1104.00
IUUC-Sce-106177	Saccharomyces cerevisiae	34.61	2.00e-76	280.00
IUUC-Sha-107006	Sarcophilus harrisii	89.54	0.00e+00	1088.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.25	2.00e-93	336.00
IUUC-Spo-108020	Schizosaccharomyces pombe	45.63	7.00e-96	344.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	44.00	1.00e-104	374.00
IUUC-Smo-108809	Selaginella moellendorffii	42.75	3.00e-104	372.00
IUUC-Sit-110581	Setaria italica	39.19	8.00e-107	381.00
IUUC-Sly-111870	Solanum lycopersicum	39.97	9.00e-111	394.00
IUUC-Stu-112283	Solanum tuberosum	39.93	9.00e-108	384.00
IUUC-Sar-113432	Sorex araneus	65.62	3.00e-139	488.00
IUUC-Sbi-114075	Sorghum bicolor	38.05	1.00e-107	383.00
IUUC-Sre-114926	Sporisorium reilianum	41.86	6.00e-104	371.00
IUUC-Ssc-116281	Sus scrofa	96.17	3.00e-107	380.00
IUUC-Tgu-117247	Taeniopygia guttata	90.03	0.00e+00	1077.00
IUUC-Tru-118075	Takifugu rubripes	71.82	0.00e+00	858.00
IUUC-Tsy-119398	Tarsius syrichta	73.77	0.00e+00	836.00
IUUC-Tni-120771	Tetraodon nigroviridis	69.83	0.00e+00	771.00
IUUC-Tca-121651	Theobroma cacao	40.69	2.00e-107	382.00
IUUC-Tre-122224	Trichoderma reesei	40.26	2.00e-98	352.00
IUUC-Tvi-122634	Trichoderma virens	43.50	3.00e-96	346.00
IUUC-Tae-125665	Triticum aestivum	40.19	2.00e-103	369.00
IUUC-Tur-126417	Triticum urartu	39.49	6.00e-104	371.00
IUUC-Tme-127016	Tuber melanosporum	45.73	1.00e-95	343.00
IUUC-Tbe-127678	Tupaia belangeri	73.37	5.00e-159	554.00
IUUC-Ttr-128598	Tursiops truncatus	84.62	0.00e+00	1032.00
IUUC-Uma-129612	Ustilago maydis	43.50	2.00e-97	350.00
IUUC-Vda-129811	Verticillium dahliae	44.71	2.00e-101	363.00
IUUC-Vpa-130732	Vicugna pacos	74.63	0.00e+00	877.00
IUUC-Vvi-130832	Vitis vinifera	41.83	5.00e-107	381.00
IUUC-Xtr-132823	Xenopus tropicalis	76.13	0.00e+00	887.00
IUUC-Xma-133552	Xiphophorus maculatus	74.72	0.00e+00	900.00
IUUC-Yli-134666	Yarrowia lipolytica	36.77	3.00e-77	282.00
IUUC-Zma-135547	Zea mays	39.29	2.00e-106	379.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence