| Tag | Content | ||||||
|---|---|---|---|---|---|---|---|
| UUCD2 ID | IUUC-Ots-000032 | ||||||
| Ensembl Protein ID | |||||||
| UniProt Accession | Q56R14; TRI33_XENLA | ||||||
| Genbank Protein ID | AAX10105.1 | ||||||
| Protein Name | E3 ubiquitin-protein ligase TRIM33; Ectodermin; RING-type E3 ubiquitin transferase TRIM33; Transcription intermediary factor 1-gamma; Tripartite motif-containing protein 33 | ||||||
| Genbank Nucleotide ID | AY781409 | ||||||
| Gene Name | trim33; ecto | ||||||
| Ensembl Information |
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| Status | Reviewed | ||||||
| Details |
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| Organism | Xenopus laevis | ||||||
| Functional Description (View) |
Acts as an E3 ubiquitin-protein ligase for smad4. Promotes ectoderm embryonic development at the expense of other germ layers. Inhibits mesodermal differentiation. Promotes neural development of the ectoderm. Promotes smad4 alpha degradation via the ubiquitin proteasome pathway. May act as a transcriptional repressor (By similarity). | ||||||
| Protein Sequence (Fasta) |
MADNKGGGGG GGETEGDASS NNNNNSNGAG ETGSPGETES QAVEEPESAE KAPVAAVPTD 60
TPAEENPAPS SSSVASSSAT PASSSSSPLV VNLLDTCAVC KLSLQSRDTE PKLLPCLHSF 120 It may take some time, please wait.
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| Sequence Source | UniProt | ||||||
| Keyword | KW-0103--Bromodomain |
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| Interpro | IPR003649--Bbox_C |
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| PROSITE | PS50014--BROMODOMAIN_2 |
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| Pfam | PF00439--Bromodomain |
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| SMART | SM00502--BBC |
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| Gene Ontology | GO:0005634--C:nucleus |
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| KEGG | xla:733198 | ||||||
| Created Date | 25-Jun-2017 |
