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Tag Content
UUCD2 ID IUUC-Ots-000040
Ensembl Protein ID
UniProt Accession Q6T486; Q54L21; RBRA_DICDI
Genbank Protein ID AAR10851.1; EAL63978.1
Protein Name Probable E3 ubiquitin-protein ligase rbrA; Ariadne-like ubiquitin ligase
Genbank Nucleotide ID AY437441; AAFI02000092
Gene Name rbrA; DDB_G0286961
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 17031003
Organism Dictyostelium discoideum
Functional Description
(View)

Functional Description



     Might act as an E3 ubiquitin-protein ligase. Appears to be required for normal cell-type proportioning and cell sorting during multicellular development. In addition to being necessary for a normal percentage of prestalk cells and the organization of the slug, rbrA is also necessary for spore cell viability.
Might act as an E3 ubiquitin-protein ligase. Appears to be required for normal cell-type proportioning and cell sorting during multicellular development. In addition to being necessary for a normal percentage of prestalk cells and the organization of the slug, rbrA is also necessary for spore cell viability.
Protein Sequence
(Fasta)
MTDDEMYEDY DVDDDSAEES GNESLDDTEY DDAATQEFDF DENQPQRSLG KLTRQKSFEV 60
LNKDDLFSES HKIIKEVKDV LSIPSEAAVS TLLRHMKWNK EKLIERYMEN PEKLCIDAGV 120
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Protein Fasta Sequence



>IUUC-Ots-000040|E3,RING|Dictyostelium discoideum
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Sequence Source UniProt
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030435--P:sporulation resulting in formation of a cellular spore

KEGG ddi:DDB_G0286961
Created Date 25-Jun-2017

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