Tag | Content | ||||||
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UUCD2 ID | IUUC-Ots-000019 | ||||||
Ensembl Protein ID | |||||||
UniProt Accession | P0C6X7; P59641; Q6WGN0; Q7T697; Q808C0; Q80BV7; Q80BV8; Q80E51; R1AB_CVHSA | ||||||
Genbank Protein ID | AAP13442.1; AAP13440.1; AAP41036.1; AAP13566.1; AAP30711.1; AAP49011.4; AAP30028.1; AAP51225.1; AAP37015.1; AAP50483.1; AAP33696.1; AAP72973.2; AAQ01594.1; AAQ01596.1; AAQ01606.1; AAQ01608.1; AAP97879.1; AAP97881.1; BAC81346.1; BAC81360.1; BAC81374.1; BAC81388.1; BAC81402.1; AAQ94058.1; AAP82966.1; AAP82975.1; AAP82967.1; AAP82978.2; AAP04003.1; AAP04587.1 | ||||||
Protein Name | Replicase polyprotein 1ab; ORF1ab polyprotein; Host translation inhibitor nsp1; Leader protein; Non-structural protein 2; p65 homolog; Papain-like proteinase; Non-structural protein 3; PL2-PRO; SARS coronavirus main proteinase; Non-structural protein 4; 3C-like proteinase; nsp5; Non-structural protein 6; Non-structural protein 7; Non-structural protein 8; Non-structural protein 9; Non-structural protein 10; Growth factor-like peptide; RNA-directed RNA polymerase; nsp12; Helicase; nsp13; Guanine-N7 methyltransferase; nsp14; Uridylate-specific endoribonuclease; NendoU; nsp15; 2'-O-methyltransferase; nsp16 | ||||||
Genbank Nucleotide ID | AY278741; AY278741; AY274119; AY278554; AY282752; AY304495; AY278488; AY278489; AY278490; AY310120; AY291315; AY323977; AY321118; AY338174; AY338175; AY338175; AY348314; AY348314; AP006557; AP006558; AP006559; AP006560; AP006561; AY427439; AY322205; AY322206; AY322207; AY463059; AY269391; AY268049 | ||||||
Gene Name | rep; 1a-1b | ||||||
Ensembl Information |
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Status | Reviewed | ||||||
Details |
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Organism | Human SARS coronavirus | ||||||
Functional Description (View) |
2'-O-methyltransferase: Methyltransferase that mediates mRNA cap 2'-O-ribose methylation to the 5'-cap structure of viral mRNAs. N7-methyl guanosine cap is a prerequisite for binding of nsp16. Therefore plays an essential role in viral mRNAs cap methylation which is essential to evade immune system. | ||||||
Protein Sequence (Fasta) |
MESLVLGVNE KTHVQLSLPV LQVRDVLVRG FGDSVEEALS EAREHLKNGT CGLVELEKGV 60
LPQLEQPYVF IKRSDALSTN HGHKVVELVA EMDGIQYGRS GITLGVLVPH VGETPIAYRN 120 It may take some time, please wait.
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Sequence Source | UniProt | ||||||
Keyword | KW-0002--3D-structure |
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Interpro | IPR027351--(+)RNA_virus_helicase_core_dom |
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PROSITE | PS51653--CV_ZBD |
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Pfam | PF16348--Corona_NSP4_C |
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SMART | SM00506--A1pp |
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Gene Ontology | GO:0039714--C:cytoplasmic viral factory |
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KEGG | vg:1489680 | ||||||
Created Date | 25-Jun-2017 |