iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.90e-23	82.3	1141	1211

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
            p+ef++p++ +lM+dPvvlpsG ++dr+ I ++l ++ + +P++rqplte++lv n++l++ i+aw++e++
   Q: 1141 APDEFKDPLMDTLMSDPVVLPSGTVMDRAIITRHLLNSCT-DPFNRQPLTEDMLVANIELKQRIDAWRKEQR 1211
           79********************************999998.**************************99875 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPEEEPPQKP MEEEEDDDQE QDQDQDHEQD QHEQDQQPQL AQGEIPGQQL PEQPNPDVQP 60
QQPAESVVVT ELSAEEMRAR RLRTLAARSG IQCALAPLTT TPRKPTNVSG ESRLVREATP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCAGATA TTTTCAAACT AGTTCTCTTA GAGCAAAAAG GATATATAAA TTGGGTATAG 60
ATGCTTAGAG AACATTATTG CAATTAAAGG CAAAAACAAA AGTGCAAATT TAAAATTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

dme:Dmel_CG9934

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002396	Ailuropoda melanoleuca	42.29	0.00e+00	637.00
IUUC-Atr-002479	Amborella trichopoda	28.59	8.00e-86	311.00
IUUC-Apl-003747	Anas platyrhynchos	42.12	0.00e+00	650.00
IUUC-Aca-004866	Anolis carolinensis	41.87	0.00e+00	657.00
IUUC-Aly-006300	Arabidopsis lyrata	28.59	3.00e-79	289.00
IUUC-Ath-006962	Arabidopsis thaliana	27.28	2.00e-76	280.00
IUUC-Ago-007880	Ashbya gossypii	28.86	8.00e-80	291.00
IUUC-Acl-008289	Aspergillus clavatus	29.99	1.00e-85	310.00
IUUC-Afl-008711	Aspergillus flavus	31.56	2.00e-90	326.00
IUUC-Afu-008766	Aspergillus fumigatus	30.31	5.00e-90	325.00
IUUC-Ani-009126	Aspergillus nidulans	29.65	2.00e-84	306.00
IUUC-Ang-009837	Aspergillus niger	31.01	6.00e-89	321.00
IUUC-Aor-009919	Aspergillus oryzae	31.56	5.00e-90	325.00
IUUC-Ate-010300	Aspergillus terreus	31.81	5.00e-92	332.00
IUUC-Ame-011355	Astyanax mexicanus	42.23	0.00e+00	696.00
IUUC-Bgr-011995	Blumeria graminis	32.61	8.00e-99	354.00
IUUC-Bta-013056	Bos taurus	42.00	0.00e+00	637.00
IUUC-Bci-013605	Botrytis cinerea	29.21	2.00e-82	300.00
IUUC-Bdi-015032	Brachypodium distachyon	28.75	2.00e-83	303.00
IUUC-Cel-018606	Caenorhabditis elegans	30.28	7.00e-99	354.00
IUUC-Cja-018872	Callithrix jacchus	42.00	0.00e+00	642.00
IUUC-Cfa-020045	Canis familiaris	42.29	0.00e+00	637.00
IUUC-Cpo-022309	Cavia porcellus	39.12	0.00e+00	647.00
IUUC-Cre-022726	Chlamydomonas reinhardtii	35.44	7.00e-46	177.00
IUUC-Csa-024003	Chlorocebus sabaeus	33.03	5.00e-72	265.00
IUUC-Cho-025092	Choloepus hoffmanni	42.34	2.00e-69	256.00
IUUC-Cin-025533	Ciona intestinalis	41.98	0.00e+00	651.00
IUUC-Csv-026081	Ciona savignyi	55.91	1.00e-51	194.00
IUUC-Cgl-026710	Colletotrichum gloeosporioides	30.60	1.00e-95	343.00
IUUC-Cne-027098	Cryptococcus neoformans	30.17	6.00e-99	355.00
IUUC-Cme-027352	Cyanidioschyzon merolae	29.47	5.00e-83	301.00
IUUC-Dre-027979	Danio rerio	42.35	0.00e+00	659.00
IUUC-Dno-029282	Dasypus novemcinctus	42.29	0.00e+00	637.00
IUUC-Dor-030904	Dipodomys ordii	53.70	3.00e-76	280.00
IUUC-Dse-031393	Dothistroma septosporum	29.35	2.00e-90	326.00
IUUC-Ete-032519	Echinops telfairi	56.35	3.00e-102	366.00
IUUC-Eca-033778	Equus caballus	41.74	7.00e-180	624.00
IUUC-Eeu-035315	Erinaceus europaeus	55.61	4.00e-59	223.00
IUUC-Fca-035658	Felis catus	42.06	0.00e+00	633.00
IUUC-Fal-037638	Ficedula albicollis	42.36	0.00e+00	653.00
IUUC-Fox-037909	Fusarium oxysporum	29.77	5.00e-84	305.00
IUUC-Fso-038406	Fusarium solani	30.30	6.00e-83	302.00
IUUC-Gmo-039379	Gadus morhua	39.36	0.00e+00	676.00
IUUC-Ggr-039851	Gaeumannomyces graminis	29.71	5.00e-88	318.00
IUUC-Gga-041136	Gallus gallus	42.15	0.00e+00	653.00
IUUC-Gac-041910	Gasterosteus aculeatus	39.08	0.00e+00	687.00
IUUC-Ggo-045354	Gorilla gorilla	39.82	5.00e-167	581.00
IUUC-Hsa-046880	Homo sapiens	41.77	0.00e+00	642.00
IUUC-Hvu-047157	Hordeum vulgare	29.16	5.00e-80	291.00
IUUC-Itr-048213	Ictidomys tridecemlineatus	56.80	3.00e-107	380.00
IUUC-Kpa-049211	Komagataella pastoris	27.70	2.00e-73	270.00
IUUC-Lch-050534	Latimeria chalumnae	42.18	0.00e+00	651.00
IUUC-Loc-052622	Lepisosteus oculatus	41.86	0.00e+00	661.00
IUUC-Lma-053241	Leptosphaeria maculans	29.65	3.00e-85	309.00
IUUC-Laf-053646	Loxodonta africana	42.18	0.00e+00	638.00
IUUC-Mcc-055588	Macaca mulatta	41.88	0.00e+00	637.00
IUUC-Meu-055999	Macropus eugenii	38.05	2.00e-142	499.00
IUUC-Mor-057064	Magnaporthe oryzae	29.02	4.00e-85	309.00
IUUC-Mpo-057452	Magnaporthe poae	30.26	7.00e-91	328.00
IUUC-Mtr-058016	Medicago truncatula	29.08	2.00e-90	327.00
IUUC-Mla-058887	Melampsora laricipopulina	32.02	6.00e-101	361.00
IUUC-Mga-059497	Meleagris gallopavo	42.36	0.00e+00	653.00
IUUC-Mvi-060343	Microbotryum violaceum	29.71	2.00e-92	333.00
IUUC-Mmr-061173	Microcebus murinus	39.64	5.00e-153	534.00
IUUC-Mdo-062102	Monodelphis domestica	37.92	0.00e+00	654.00
IUUC-Mmu-063223	Mus musculus	38.92	0.00e+00	651.00
IUUC-Mac-065531	Musa acuminata	28.54	1.00e-87	317.00
IUUC-Mpu-066624	Mustela putorius furo	47.63	1.00e-119	423.00
IUUC-Mlu-068018	Myotis lucifugus	42.52	0.00e+00	639.00
IUUC-Nfi-068590	Neosartorya fischeri	30.23	7.00e-90	324.00
IUUC-Ncr-068901	Neurospora crassa	31.36	1.00e-96	347.00
IUUC-Nle-069605	Nomascus leucogenys	42.03	0.00e+00	631.00
IUUC-Opr-071011	Ochotona princeps	54.83	7.00e-97	348.00
IUUC-Ont-072304	Oreochromis niloticus	42.08	0.00e+00	659.00
IUUC-Oan-073410	Ornithorhynchus anatinus	48.92	1.00e-148	519.00
IUUC-Ocu-074910	Oryctolagus cuniculus	42.11	0.00e+00	645.00
IUUC-Ogu-078116	Oryza glumaepatula	28.59	3.00e-86	312.00
IUUC-Olo-080253	Oryza longistaminata	27.49	5.00e-75	275.00
IUUC-Oni-082019	Oryza nivara	28.59	3.00e-86	313.00
IUUC-Opu-083558	Oryza punctata	29.01	1.00e-86	313.00
IUUC-Ola-086323	Oryzias latipes	46.41	0.00e+00	669.00
IUUC-Olu-087901	Ostreococcus lucimarinus	30.60	2.00e-86	313.00
IUUC-Oga-087969	Otolemur garnettii	44.46	4.00e-171	595.00
IUUC-Oar-090020	Ovis aries	41.15	0.00e+00	634.00
IUUC-Ptr-091589	Pan troglodytes	41.77	0.00e+00	642.00
IUUC-Pan-091718	Papio anubis	52.30	5.00e-128	451.00
IUUC-Psi-093013	Pelodiscus sinensis	42.26	0.00e+00	655.00
IUUC-Pma-094627	Petromyzon marinus	56.52	1.00e-134	471.00
IUUC-Pno-094840	Phaeosphaeria nodorum	32.03	8.00e-98	351.00
IUUC-Ppa-095989	Physcomitrella patens	28.89	2.00e-83	303.00
IUUC-Pfo-096436	Poecilia formosa	42.38	0.00e+00	672.00
IUUC-Pab-098275	Pongo abelii	48.92	5.00e-148	518.00
IUUC-Pop-100005	Populus trichocarpa	28.47	5.00e-93	335.00
IUUC-Pca-100478	Procavia capensis	37.68	1.00e-84	307.00
IUUC-Pva-102459	Pteropus vampyrus	43.38	9.00e-176	610.00
IUUC-Pgr-103485	Puccinia graminis	31.54	1.00e-101	363.00
IUUC-Ptt-104001	Puccinia triticina	36.78	2.00e-38	153.00
IUUC-Pte-104084	Pyrenophora teres	28.89	2.00e-99	356.00
IUUC-Pyt-104484	Pyrenophora triticirepentis	29.91	5.00e-101	362.00
IUUC-Rno-105719	Rattus norvegicus	38.96	0.00e+00	653.00
IUUC-Sce-106135	Saccharomyces cerevisiae	28.42	3.00e-69	256.00
IUUC-Sha-106760	Sarcophilus harrisii	38.01	0.00e+00	656.00
IUUC-Sja-107698	Schizosaccharomyces japonicus	30.30	1.00e-94	340.00
IUUC-Spo-108076	Schizosaccharomyces pombe	32.06	2.00e-95	343.00
IUUC-Ssl-108624	Sclerotinia sclerotiorum	29.66	3.00e-88	319.00
IUUC-Smo-109042	Selaginella moellendorffii	27.64	9.00e-80	291.00
IUUC-Stu-112372	Solanum tuberosum	28.88	5.00e-88	318.00
IUUC-Sar-113469	Sorex araneus	31.18	4.00e-63	236.00
IUUC-Sre-114967	Sporisorium reilianum	31.37	6.00e-103	368.00
IUUC-Ssc-115721	Sus scrofa	57.14	7.00e-90	322.00
IUUC-Tgu-117290	Taeniopygia guttata	42.10	0.00e+00	631.00
IUUC-Tru-118193	Takifugu rubripes	41.95	0.00e+00	665.00
IUUC-Tsy-118926	Tarsius syrichta	41.95	0.00e+00	635.00
IUUC-Tni-120862	Tetraodon nigroviridis	40.00	0.00e+00	668.00
IUUC-Tca-121096	Theobroma cacao	29.40	1.00e-91	330.00
IUUC-Tre-122104	Trichoderma reesei	31.25	2.00e-93	337.00
IUUC-Tvi-122345	Trichoderma virens	30.80	1.00e-92	334.00
IUUC-Tae-124607	Triticum aestivum	29.22	6.00e-83	301.00
IUUC-Tme-127074	Tuber melanosporum	29.30	2.00e-88	320.00
IUUC-Tbe-127533	Tupaia belangeri	43.38	2.00e-176	612.00
IUUC-Ttr-128757	Tursiops truncatus	41.13	2.00e-178	619.00
IUUC-Uma-129550	Ustilago maydis	30.70	1.00e-104	373.00
IUUC-Vda-129901	Verticillium dahliae	30.95	1.00e-96	347.00
IUUC-Vpa-130636	Vicugna pacos	48.43	2.00e-140	493.00
IUUC-Vvi-130891	Vitis vinifera	28.43	3.00e-88	319.00
IUUC-Xtr-132364	Xenopus tropicalis	42.28	0.00e+00	630.00
IUUC-Xma-133772	Xiphophorus maculatus	42.49	0.00e+00	674.00
IUUC-Yli-134506	Yarrowia lipolytica	29.27	1.00e-79	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence