PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9ZVH4 - 15659098 - X 2 O22286 Q9ZVH4 - 15772280 - X 2 Q9ZVH4 Q9XHZ8 - 15659098 - X 2 Q9ZVH4 Q8W207 - 12615944 - X 2 Q9ZVH4 Q9XHZ8 - 15772280 - X 2 Q9LQ95 Q9ZVH4 - 15772280 - X 2 O65020 Q9ZVH4 - 15118728 - X 2 Q6EJ98 Q9ZVH4 - 15772280 - X 2 Q9FMK7 Q9ZVH4 - 15772280 - X 2 Q9ZVH4 Q8L765-2 - 15772280 - X 2 Q9ZVH4 A1L4W5 - 15772280 - X 2 Q9ZVH4 Q94BN0 - 15772280 - X 2 Q9ZVH4 Q9SYL0 - 15772280 - X 2 Q9LV63 Q9ZVH4 - 15772280 - X 2 Q9M8J9 Q9ZVH4 - 15772280 - X 2 Q9ZVH4 Q8W207 two hybrid 12615944 direct interaction X 2 Q9ZVH4 B7U179 two hybrid 15659098 direct interaction X 2 Q9ZVH4 Q9XHZ8 two hybrid 15659098 direct interaction X 2 Q9ZVH4 Q6DBN1 two hybrid 15749712 direct interaction X 2 Q9ZVH4 Q9XHZ8 two hybrid 15749712 direct interaction X 2 Q9ZVH4 Q9XHZ8 pull down 15772280 direct interaction X 2 Q9ZVH4 F4JAT1 pull down 15772280 direct interaction X 2 Q9ZVH4 Q9XHZ8 two hybrid 15772280 direct interaction X 2 Q9ZVH4 Q9XHZ8 biochemical 15772280 colocalization X 2 Q9LQ95 Q9ZVH4 pull down 15772280 direct interaction X 2 Q6EJ98 Q9ZVH4 pull down 15772280 direct interaction X 2 B9DGE3 Q9ZVH4 biochemical 15772280 colocalization X 2 Q9FMK7 Q9ZVH4 pull down 15772280 direct interaction X 2 Q9SHE7 Q9ZVH4 pull down 15618422 direct interaction X 2 Q9ZVH4 Q8L765-2 two hybrid 15618422 direct interaction X 2 Q9ZVH4 Q8L765-2 pull down 15618422 direct interaction X 2 Q9ZVH4 F4K5K1 two hybrid 15618422 direct interaction X 2 Q9ZVH4 F4K5K1 pull down 15618422 direct interaction X 2 Q9ZVH4 Q8L765-2 two hybrid 15618422 direct interaction X 2 Q9ZVH4 Q6X5Y6-3 affinity chromatography technology 23792371 physical association X 2 Q9ZVH4 Q6X5Y6-3 biochemical 23792371 colocalization X 2 Q9ZVH4 Q66GP0 affinity chromatography technology 24528504 physical association X 2 Q9ZVH4 F4J4I9 pull down 15118728 direct interaction X 2 Q9ZVH4 F4J4I9 pull down 15118728 direct interaction X 2 Q9ZVH4 F4K5K1 two hybrid 15659098 direct interaction X 2 Q9ZVH4 Q8L765-2 two hybrid 15749712 direct interaction X 2 Q9ZVH4 Q8L765-2 pull down 15772280 direct interaction X 2 Q9ZVH4 Q9SYL0 pull down 15772280 direct interaction X 2 Q9ZVH4 Q94BN0 pull down 15772280 direct interaction X 2 Q9ZVH4 F4K5K1 affinity chromatography technology 15772280 physical association X 2 Q9ZVH4 F4K5K1 biochemical 15772280 colocalization X 2 Q9ZVH4 F4K5K1 two hybrid 16792691 direct interaction X 2 Q9ZVH4 F4K5K1 two hybrid 15749712 direct interaction X 2 Q9ZVH4 Q9FMF5 affinity chromatography technology 21990941 physical association X 2 O22286-2 Q9ZVH4 two hybrid 15618422 direct interaction X 2 O22286-2 Q9ZVH4 two hybrid 15659098 direct interaction X 2 O22286-2 Q9ZVH4 pull down 15772280 direct interaction X 2 Q9LV63 Q9ZVH4 pull down 15772280 direct interaction X 2 Q8L746 Q9ZVH4 pull down 22699612 physical association X 2 Q9ZVH4 P93002 anti tag coimmunoprecipitation 22699612 physical association X 2 Q9ZVH4 Q5ICL9 pull down 22699612 physical association X 2 Q9ZVH4 pull down 22699612 - C 3 Q9XH28 Q9ZVH4 two hybrid 15749712 physical association X 2 Q9XH28 Q9ZVH4 two hybrid 15749712 physical association X 2 Q9ZVH4 Q8W207 two hybrid 12615944 physical association X 2 O22286 Q9ZVH4 two hybrid 15618422 physical association X 2 Q9ZVH4 Q9XHZ8 two hybrid 15659098 physical association X 2 Q9ZVH4 B7U179 two hybrid 15659098 physical association X 2 O22286 Q9ZVH4 two hybrid 15659098 physical association X 2 Q9ZVH4 Q6DBN1 two hybrid 15749712 physical association X 2 Q9ZVH4 Q6DBN1 two hybrid 15749712 physical association X 2 Q9ZVH4 Q9XHZ8 pull down 15772280 physical association X 2 Q9ZVH4 Q9XHZ8 pull down 15772280 physical association X 2 Q9ZVH4 Q9XHZ8 two hybrid 15772280 physical association X 2 O22286 Q9ZVH4 pull down 15772280 physical association X 2 Q9ZVH4 P93002 anti bait coimmunoprecipitation 19490895 physical association X 2 Q9ZVH4 P93002 anti bait coimmunoprecipitation 19490895 physical association X 2 Q9LQ95 Q9ZVH4 pull down 15772280 physical association X 2 Q6EJ98 Q9ZVH4 pull down 15772280 physical association X 2 Q9FMK7 Q9ZVH4 pull down 15772280 physical association X 2 Q8L765 Q9ZVH4 two hybrid 15618422 physical association X 2 Q8L765 Q9ZVH4 pull down 15618422 physical association X 2 Q8L765 Q9ZVH4 two hybrid 15749712 physical association X 2 Q8L765 Q9ZVH4 two hybrid 15749712 physical association X 2 Q8L765 Q9ZVH4 pull down 15772280 physical association X 2 Q9ZVH4 Q94BN0 pull down 15772280 physical association X 2 Q9ZVH4 A1L4W5 pull down 15772280 physical association X 2 Q9ZVH4 Q9SYL0 pull down 15772280 physical association X 2 Q9LV63 Q9ZVH4 pull down 15772280 physical association X 2 Q940X7 Q9ZVH4 two hybrid 15618422 physical association X 2 Q940X7 Q9ZVH4 pull down 15618422 physical association X 2 Q940X7 Q9ZVH4 two hybrid 15659098 physical association X 2 Q940X7 Q9ZVH4 two hybrid 16792691 physical association X 2 Q9M8J9 Q9ZVH4 pull down 15772280 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B F10A2.10 CUL3A MI:0018(two hybrid)|MI:0018(two hybrid) 15749712 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_12829|UniProt_12823 prey|prey bait|bait BPM3 CUL3A MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 15618422,15659098,15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact) BIOGRID_16579|BIOGRID_2631|BIOGRID_2600|UniProt_13491|UniProt_11945|UniProt_12199 prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait At1g01640 CUL3A MI:0096(pull down)|MI:0096(pull down) 15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_2633|UniProt_13493 prey|prey bait|bait NPR1 CUL3A MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 19490895 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_10397|UniProt_10394 prey|prey bait|bait WRI1 CUL3A MI:0018(two hybrid)|MI:0018(two hybrid) 23792371 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_17976|BIOGRID_17975 bait|bait prey|prey At4g08455 CUL3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15749712 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_12821|BIOGRID_2619|UniProt_12827 prey|prey|prey bait|bait|bait CUL3A BPM6 MI:0096(pull down) 15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_13497 bait prey BPM1 CUL3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15618422,15749712,15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(biogrid)|(intact)|(intact)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid) UniProt_12822|UniProt_11958|BIOGRID_2629|UniProt_11946|UniProt_12828|BIOGRID_16581|UniProt_13489|BIOGRID_16595|BIOGRID_16577|BIOGRID_2621 prey|bait|prey|prey|prey|bait|prey|bait|prey|prey bait|prey|bait|bait|bait|prey|bait|prey|bait|bait ETO1 CUL3A MI:0018(two hybrid)|MI:0018(two hybrid) 15118728 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_2483|BIOGRID_2482 bait|prey prey|bait BT5 CUL3A MI:0096(pull down)|MI:0096(pull down) 15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_2632|UniProt_13492 prey|prey bait|bait At1g21780 CUL3A MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down) 15659098,15749712,15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0403(colocalization)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid) UniProt_13499|UniProt_13501|BIOGRID_2628|BIOGRID_2644|UniProt_12201|BIOGRID_2620|BIOGRID_2602|UniProt_13488|BIOGRID_2639 prey|prey|prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait|bait|bait BT2 CUL3A MI:0096(pull down)|MI:0096(pull down) 15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_13495|BIOGRID_2637 prey|prey bait|bait CUL3A ABAP1 MI:0018(two hybrid)|MI:0018(two hybrid) 15659098 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_12204|BIOGRID_2601 bait|bait prey|prey RBX1A CUL3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15618422,15659098,15749712,15772280,16792691 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid) BIOGRID_4780|BIOGRID_16590|BIOGRID_2641|UniProt_11956|BIOGRID_2642|UniProt_12485|UniProt_12195|UniProt_11962|BIOGRID_5831|BIOGRID_2597|BIOGRID_16592 prey|prey|prey|prey|prey|prey|prey|bait|prey|prey|bait bait|bait|bait|bait|bait|bait|bait|prey|bait|bait|prey RPT3 CUL3A MI:0004(affinity chromatography technology) 21990941 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (biogrid) BIOGRID_8049 prey bait BT3 CUL3A MI:0096(pull down)|MI:0096(pull down) 15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_13498|BIOGRID_2636 prey|prey bait|bait RUB1 CUL3A MI:0018(two hybrid) 15618422 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_16593 bait prey BPM2 CUL3A MI:0096(pull down)|MI:0096(pull down) 15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_2630|UniProt_13490 prey|prey bait|bait At5g67385 CUL3A MI:0018(two hybrid) 24528504 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (biogrid) BIOGRID_21173 bait prey At5g48510 CUL3A MI:0096(pull down)|MI:0096(pull down) 15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_2634|UniProt_13494 prey|prey bait|bait CSN2 CUL3A MI:0018(two hybrid)|MI:0401(biochemical) 12615944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_16522|BIOGRID_2182 bait|prey prey|bait BT1 CUL3A MI:0096(pull down)|MI:0096(pull down) 15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_13496|BIOGRID_2638 prey|prey bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9ZVH4 Q9FMK7 CUL3A BT1 0.454 15772280 Q9ZVH4 Q9LQ95 CUL3A Q9LQ95 0.454 15772280 Q9ZVH4 Q9M8J9 CUL3A BPM2 0.454 15772280 Q9ZVH4 O65020 CUL3A ETO1 0.523 15118728 Q9ZVH4 P43255 CUL3A CSN8 0.21 19490895 Q9ZVH4 Q8L5U0 CUL3A CSN4 0.21 19490895 Q9ZVH4 Q8LAZ7 CUL3A CSN5B 0.21 19490895 Q9ZVH4 Q94AH6 CUL3A CUL1 0.126 15772280 Q9ZVH4 Q9FMF5 CUL3A RPT3 0.21 21990941 Q9ZVH4 Q9XH28 CUL3A F10A2.10 0.309 15749712 Q9ZVH4 Q6R053 CUL3A MYB56 {ECO:0000303|PUBMED:9839469} 0.21 25618823 Q9ZVH4 Q66GP0 CUL3A Q66GP0 0.21 24528504 Q9ZVH4 Q6DBN1 CUL3A Q6DBN1 0.671 15749712 Q9ZVH4 Q9LV63 CUL3A Q9LV63 0.454 15772280 Q9ZVH4 Q6EJ98 CUL3A BT5 0.454 15772280 Q9ZVH4 Q94BN0 CUL3A BT2 0.454 15772280 Q9ZVH4 Q9XHZ8 CUL3A Q9XHZ8 0.941 15659098,15772280,15749712 Q9ZVH4 Q6X5Y6 CUL3A WRI1 0.309 23792371 Q9ZVH4 O22286 CUL3A BPM3 0.876 15659098,15772280,15618422 Q9ZVH4 Q8L765 CUL3A BPM1 0.968 15772280,15749712,15618422 Q9ZVH4 Q940X7 CUL3A RBX1A 0.972 15659098,16792691,15618422,15772280,15749712 Q9ZVH4 Q8W207 CUL3A CSN2 0.332 12615944 Q9ZVH4 Q9SYL0 CUL3A BT3 0.454 15772280 Q9ZVH4 Q9SHE7 CUL3A RUB1 0.309 15618422 Q9ZVH4 B7U179 CUL3A ABAP1 0.523 15659098 Q9ZVH4 A1L4W5 CUL3A BPM6 0.21 15772280 Q9ZVH4 P93002 CUL3A NPR1 0.507 19490895