PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9SHE7 B9DGE3 affinity chromatography technology 22893627 physical association X 2 Q9SHE7 B9DGE3 affinity chromatography technology 15319484 physical association X 2 Q9SHE7 Q9ZVH4 pull down 15618422 direct interaction X 2 Q9SHE7 Q9C9L0 pull down 15618422 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CUL3B RUB1 MI:0018(two hybrid) 15618422 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_16594 prey bait RUB1 CUL3A MI:0018(two hybrid) 15618422 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_16593 bait prey

PPI - HINT Gene A Gene B PMID Method Quality AXR1 RUB1 25783028 0004 LC CUL1 RUB1 15319484,22893627 0004,0004 LC CUL3B RUB1 15618422 0096 LC RUB1 CUL3A 15618422 0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9SHE7 Q94AH6 RUB1 CUL1 0.376 15319484,22893627 Q9SHE7 Q9C9L0 RUB1 CUL3B 0.309 15618422 Q9ZVH4 Q9SHE7 CUL3A RUB1 0.309 15618422 Q9SHE7 P42744 RUB1 AXR1 0.21 25783028