PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8H1U5 two hybrid 14508008 direct interaction X 2 Q8H1U5 Q06AN9 two hybrid 14508008 direct interaction X 2 Q8H1U5 two hybrid 14508008 direct interaction X 2 Q8H1U5 affinity chromatography technology 14508008 physical association X 2 Q8H1U5 B3DNN5 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 O65418 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 O48533 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q9C5U3 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q06AN9 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q8VZS9 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q9SZA4 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q8LPL5 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q9STS3 two hybrid 14508008 direct interaction X 2 Q8H1U5 Q9ZPW2 two hybrid 14508008 direct interaction X 2 Q8H1U5 Q9STS3 two hybrid 14508008 direct interaction X 2 Q8H1U5 Q9STS3 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q8LGU6 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q9M2R1 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q9FFF9 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q8VY89-3 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q8H1U4 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q9CAG4 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q9ZPW2 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 Q8L3Z8 affinity chromatography technology 20706207 physical association X 2 Q8H1U5 tandem affinity purification 20706207 association C 7 Q8H1U5 tandem affinity purification 20706207 physical association C 15 Q8H1U5 tandem affinity purification 20706207 association C 14 Q8H1U5 Q06AN9 anti bait coimmunoprecipitation 17944809 physical association X 2 Q8H1U5 tandem affinity purification 20706207 association C 12 Q8H1U5 tandem affinity purification 20706207 association C 6 Q8H1U5 tandem affinity purification 20706207 physical association C 8 Q8H1U5 tandem affinity purification 20706207 physical association C 14 Q8H1U5 tandem affinity purification 20706207 physical association C 11 Q8H1U5 Q9STS3 two hybrid 14508008 physical association X 2 Q8H1U5 Q9M9L0 two hybrid 14508008 physical association X 2 Q8H1U5 Q9M9L0 two hybrid 14508008 physical association X 2 Q8H1U5 Q9STS3 two hybrid 14508008 physical association X 2 Q8H1U5 Q9M9L0 anti tag coimmunoprecipitation 14508008 physical association X 2 Q8H1U5 Q8LGU6 anti tag coimmunoprecipitation 17944809 physical association X 2 Q8H1U5 Q8LGU6 anti bait coimmunoprecipitation 17944809 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CDC27A APC2 MI:0018(two hybrid)|MI:0090(protein complementation assay)|MI:0018(two hybrid)|MI:0676(tandem affinity purification) 14508008,17944809,20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association) (intact)|(biogrid)|(biogrid)|(intact) UniProt_13980|BIOGRID_5169|BIOGRID_2408|UniProt_9175 prey|prey|prey|prey bait|bait|bait|bait APC4 APC2 MI:0676(tandem affinity purification)|MI:0090(protein complementation assay) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_9098|BIOGRID_5164 prey|prey bait|bait APC2 RPT6A MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_5167|UniProt_9175 bait|bait prey|prey APC2 APC1 MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_5163|UniProt_9098 bait|bait prey|prey APC2 At2g18290 MI:0676(tandem affinity purification)|MI:0090(protein complementation assay)|MI:0018(two hybrid) 14508008,20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid)|(biogrid) UniProt_9097|BIOGRID_5171|BIOGRID_2407 prey|prey|bait bait|bait|prey APC2 F17M5.30 MI:0676(tandem affinity purification)|MI:0090(protein complementation assay) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_9108|BIOGRID_5546 prey|prey bait|bait APC2 FZR3 MI:0676(tandem affinity purification)|MI:0090(protein complementation assay) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_9106|BIOGRID_5642 prey|prey bait|bait APC2 APC11 MI:0676(tandem affinity purification)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0090(protein complementation assay)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14508008,20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid)|(intact)|(biogrid)|(intact)|(biogrid)|(intact)|(biogrid) UniProt_9176|BIOGRID_2411|UniProt_16669|BIOGRID_5329|UniProt_16668|BIOGRID_2409|UniProt_16671|BIOGRID_2405 prey|prey|bait|prey|prey|prey|prey|bait bait|bait|prey|bait|bait|bait|bait|prey APC2 At1g67540 MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_5170|UniProt_9175 bait|bait prey|prey APC2 APC8 MI:0676(tandem affinity purification)|MI:0018(two hybrid)|MI:0090(protein complementation assay)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14508008,20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact) UniProt_9098|BIOGRID_2410|BIOGRID_5159|UniProt_16667|BIOGRID_2406|UniProt_16670 bait|prey|bait|prey|bait|bait prey|bait|prey|bait|prey|prey APC2 FZR2 MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_5526|UniProt_9184 prey|prey bait|bait UVI4 APC2 MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_5166|UniProt_9175 prey|prey bait|bait APC2 T10K17.70 MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_5162|UniProt_9098 bait|bait prey|prey APC2 APC6 MI:0676(tandem affinity purification)|MI:0090(protein complementation assay) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_9098|BIOGRID_5161 bait|bait prey|prey APC2 FZR1 MI:0676(tandem affinity purification)|MI:0090(protein complementation assay) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_9183|BIOGRID_5497 prey|prey bait|bait APC2 CDC27B MI:0676(tandem affinity purification)|MI:0018(two hybrid)|MI:0090(protein complementation assay)|MI:0018(two hybrid) 17944809,20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(intact) UniProt_9098|UniProt_13979|BIOGRID_5160|UniProt_13978 bait|bait|bait|prey prey|prey|prey|bait APC5 APC2 MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_5168|UniProt_9175 prey|prey bait|bait APC2 APC7 MI:0676(tandem affinity purification)|MI:0090(protein complementation assay) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_9098|BIOGRID_5165 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality CDC27A APC2 14508008 0018 LC APC2 APC11 14508008,14508008,14508008 0018,0007,0004 LC APC2 APC8 14508008 0018 LC APC2 APC10 14508008 0018 LC APC6 APC2 20706207,20706207 0004,0676 HT B3H4Y3 APC2 20706207,20706207 0004,0676 HT PYM APC2 20706207,20706207 0004,0676 HT APC4 APC2 20706207,20706207 0004,0676 HT NAD7 APC2 20706207 0676 HT CDC27A APC2 20706207,20706207,17944809 0004,0676,0006 HT,LC APC5 APC2 20706207,20706207 0004,0676 HT APC2 FZR2 20706207,20706207 0004,0676 HT APC2 CDC27B 20706207,20706207,17944809,17944809 0004,0676,0007,0006 HT,LC APC2 FZR3 20706207,20706207 0004,0676 HT APC2 APC7 20706207,20706207 0004,0676 HT APC2 FZR1 20706207,20706207 0004,0676 HT APC2 RPT6A 20706207,20706207 0004,0676 HT APC2 APC1 20706207,20706207 0004,0676 HT APC2 GIG1 20706207,20706207 0004,0676 HT APC2 APC11 20706207,20706207,14508008,14508008,14508008 0004,0676,0018,0007,0004 HT,LC APC2 APC8 20706207,20706207 0004,0676 HT APC2 CDC20-1 20706207,20706207 0004,0676 HT APC2 APC10 20706207,20706207 0004,0676 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8H1U5 B3H4Y3 APC2 B3H4Y3 0.126 20706207 Q8H1U5 P93306 APC2 NAD7 0.126 20706207 Q9FFF9 Q8H1U5 APC1 APC2 0.126 20706207 Q9ZPW2 Q8H1U5 APC10 APC2 0.472 20706207,14508008 Q8VZS9 Q8H1U5 FZR1 APC2 0.236 20706207 Q8L3Z8 Q8H1U5 FZR2 APC2 0.236 20706207 Q8LPL5 Q8H1U5 FZR3 APC2 0.236 20706207 Q9SZA4 Q8H1U5 CDC20-1 APC2 0.236 20706207 Q8H1U5 B3DNN5 APC2 APC6 0.236 20706207 Q8H1U5 O48533 APC2 PYM 0.236 20706207 Q8H1U5 O65418 APC2 APC4 0.236 20706207 Q8H1U5 Q8H1U4 APC2 APC5 0.236 20706207 Q8VY89 Q8H1U5 APC7 APC2 0.236 20706207 Q9C5U3 Q8H1U5 RPT6A APC2 0.236 20706207 Q9M2R1 Q8H1U5 GIG1 APC2 0.236 20706207 Q9M9L0 Q8H1U5 APC11 APC2 0.843 20706207,14508008 Q8LGU6 Q8H1U5 CDC27B APC2 0.523 20706207,17944809 Q9STS3 Q8H1U5 APC8 APC2 0.748 20706207,14508008 Q8H1U5 Q06AN9 APC2 CDC27A 0.583 20706207,17944809,14508008