PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O22607 Q9SJG4 two hybrid 23394836 direct interaction X 2 O22607 Q9SJG4 protein complementation assay 23394836 direct interaction X 2 O22607 Q9SJG4 affinity chromatography technology 23394836 physical association X 2 O22607 Q8RX28 two hybrid 24220632 direct interaction X 2 Q84JU6 O22607 two hybrid 22960247 direct interaction X 2 Q84JU6 O22607 affinity chromatography technology 22960247 physical association X 2 Q84JU6 O22607 affinity chromatography technology 22960247 physical association X 2 Q84JU6 O22607 two hybrid 24220632 direct interaction X 2 Q84JU6 O22607 pull down 24220632 direct interaction X 2 Q84JU6 O22607 affinity chromatography technology 24220632 physical association X 2 Q84JU6 O22607 protein complementation assay 24220632 direct interaction X 2 Q9FML2 O22607 pull down 24220632 direct interaction X 2 Q9FML2 O22607 affinity chromatography technology 24220632 physical association X 2 Q9FML2 O22607 protein complementation assay 24220632 direct interaction X 2 Q9FML2 O22607 two hybrid 24220632 direct interaction X 2 Q9FML2 O22607 protein complementation assay 22102827 direct interaction X 2 Q9FML2 O22607 pull down 22102827 direct interaction X 2 Q9FML2 O22607 affinity chromatography technology 22102827 physical association X 2 B3H6I9 O22607 two hybrid 21282611 direct interaction X 2 B3H6I9 O22607 protein complementation assay 21282611 direct interaction X 2 B3H6I9 O22607 affinity chromatography technology 21282611 physical association X 2 Q8H0W2 O22607 two hybrid 24220632 direct interaction X 2 O22607 Q8GXJ1 pull down 24220632 direct interaction X 2 O22607 Q8GXJ1 protein complementation assay 24220632 direct interaction X 2 O22607 Q8GXJ1 two hybrid 24220632 direct interaction X 2 O22607 Q94AI7 two hybrid 22065421 direct interaction X 2 O49552 O22607 two hybrid 21282611 direct interaction X 2 O49552 O22607 affinity chromatography technology 21282611 physical association X 2 Q9SU78 O22607 protein complementation assay 23394836 direct interaction X 2 O22607 anti tag coimmunoprecipitation 21282611 - C 3 P93831 O22607 anti tag coimmunoprecipitation 21282611 direct interaction X 2 P93831 O22607 two hybrid 21282611 direct interaction X 2 P93831 O22607 MI:0809,(-) 21282611 direct interaction X 2 O49552 O22607 two hybrid 21282611 direct interaction X 2 Q9M0V3 O22607 two hybrid 21282611 direct interaction X 2 Q9M0V3 O22607 MI:0809,(-) 21282611 direct interaction X 2 O22607 anti tag coimmunoprecipitation 24855943 association C 8

PPI - HINT Gene A Gene B PMID Method Quality MSI4 DDB1B 21282611,21282611 0004,0018 LC MSI4 DET1 25962685 0055 LC MSI4 CLF 21282611,21282611,21282611 0007,0018,0809 LC MSI4 HOS1 24220632,22960247,22960247,24220632,24220632,24220632 0004,0018,0004,0096,0090,0018 LC MSI4 HDA15 24220632,24220632,24220632 0096,0090,0018 LC MSI4 HDA9 24220632 0018 LC MSI4 HDA5 24220632 0018 LC MSI4 TPL 22065421 0018 LC MSI4 HDA6 22102827,24220632,22102827,24220632,24220632,22102827,24220632 0096,0004,0090,0096,0090,0004,0018 LC MSI4 DDB1A 21282611,21282611,21282611,21282611 0004,0018,0090,0809 LC MSI4 AHL16 23394836,23394836,23394836 0004,0090,0018 LC MSI4 MSI5 23394836 0090 LC F4K4D6 MSI4 25600937 0004 LC MSI4 DDB1B 21282611,21282611 0004,0018 LC MSI4 CLF 21282611,21282611,21282611 0007,0018,0809 LC MSI4 HOS1 24220632,22960247,22960247,24220632,24220632,24220632 0004,0018,0004,0096,0090,0018 LC MSI4 HDA15 24220632,24220632,24220632 0096,0090,0018 LC MSI4 HDA6 22102827,24220632,22102827,24220632,24220632,22102827,24220632 0096,0004,0090,0096,0090,0004,0018 LC MSI4 Q9FNE4 25600937 0004 LC MSI4 Q9LK91 25600937 0004 LC MSI4 Q9LP68 25600937,25600937 0096,0004 LC MSI4 F9G14_260 25600937 0004 LC MSI4 DDB1A 21282611,21282611,21282611,21282611 0004,0018,0090,0809 LC MSI4 T5N23_120 25600937,25600937 0096,0004 LC MSI4 ATM 25600937,25600937 0096,0004 LC MSI4 DRM2 24855943 0007 LC MSI4 F22F7.12 25600937 0004 LC MSI4 F11F8_26 25600937 0096 LC MSI4 AHL16 23394836,23394836,23394836 0004,0090,0018 LC