PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O22286 Q9ZVH4 - 15772280 - X 2 Q8L402 O22286 two hybrid array 21798944 physical association X 2 P46601 O22286 two hybrid array 21798944 physical association X 2 O22286 Q9ZVH4 two hybrid 15618422 physical association X 2 O22286 A1L4W5 two hybrid 15618422 physical association X 2 O22286 Q9ZVH4 two hybrid 15659098 physical association X 2 O22286 Q9ZVH4 pull down 15772280 physical association X 2 O22286 Q38828 two hybrid array 21798944 physical association X 2 O22286 Q42551 two hybrid array 21798944 physical association X 2 O22286 Q9FNI1 two hybrid array 21798944 physical association X 2 O22286 Q9SGR1 two hybrid array 21798944 physical association X 2 O22286 O23212 two hybrid array 21798944 physical association X 2 O22286 Q93VG8 two hybrid array 21798944 physical association X 2 O22286 Q9LK47 two hybrid array 21798944 physical association X 2 Q8LPT3 O22286 two hybrid array 21798944 physical association X 2 Q9C9L0 O22286 two hybrid 15618422 physical association X 2 Q9C9L0 O22286 two hybrid 15659098 physical association X 2 Q940H8 O22286 two hybrid array 21798944 physical association X 2 O22286 O22286 two hybrid 15618422 physical association X 2 O22286 Q1EBV6 two hybrid 15618422 physical association X 2 O22286 Q8H1E4 pull down 19843165 direct interaction X 2 O22286 Q8H1E4 two hybrid 19843165 physical association X 2 O22286 Q9LM15 two hybrid 19843165 physical association X 2 O22286 O22286 two hybrid array 21798944 physical association X 2 O22286 Q8VY20 two hybrid array 21798944 physical association X 2 O22286 Q6NPE4 two hybrid array 21798944 physical association X 2 O22286 O49653 two hybrid array 21798944 physical association X 2 O22286 Q940T3 two hybrid array 21798944 physical association X 2 O22286 Q96321 two hybrid array 21798944 physical association X 2 O22286 Q8LB89 two hybrid array 21798944 physical association X 2 O22286 Q9SJU0 two hybrid array 21798944 physical association X 2 O22286 Q9ZSZ8 two hybrid array 21798944 physical association X 2 Q6NQ80 O22286 two hybrid array 21798944 physical association X 2 P46602 O22286 two hybrid array 21798944 physical association X 2 Q8L765 O22286 two hybrid 15618422 physical association X 2 Q8L765 O22286 two hybrid 15618422 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B BPM3 At4g14740 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_11621|UniProt_1801 bait|bait prey|prey BPM3 At4g17486 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_11942|UniProt_6626 bait|prey prey|bait BPM3 CUL3A MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 15618422,15659098,15772280 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact) BIOGRID_16579|BIOGRID_2631|BIOGRID_2600|UniProt_13491|UniProt_11945|UniProt_12199 prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait BPM3 KAP1 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_12644|UniProt_7228 bait|prey prey|bait BPM3 IAA10 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_9392|UniProt_2734 prey|prey bait|bait BPM3 At1g79910 MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_11157 prey bait BPM3 uniprotkb:(gene name) MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_6827 prey bait BPM3 Z97337.18 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_8611|UniProt_6806 bait|prey prey|bait BPM3 ATHB-16 MI:0018(two hybrid) 22172674 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_14950 bait prey BPM3 FIP37 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_9880|BIOGRID_9777 prey|bait bait|prey BPM3 At4g27870 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_11530|UniProt_6148 bait|prey prey|bait BPM3 At5g06270 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_9162|UniProt_1802 bait|bait prey|prey BPM3 SCE1 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_11246|UniProt_2917 bait|prey prey|bait BPM3 BPM6 MI:0018(two hybrid) 15618422 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_11955 bait prey BPM3 CUL3B MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15618422,15659098 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|(intact) BIOGRID_16580|BIOGRID_2603|UniProt_12200|UniProt_11947 prey|prey|prey|prey bait|bait|bait|bait BPM3 WRI1 MI:0018(two hybrid) 23792371 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_17970 prey bait BPM3 At2g21380 MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_5431 prey bait BPM3 BPM1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15618422 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid)|(intact)|(biogrid) UniProt_11953|BIOGRID_16587|UniProt_11949|BIOGRID_16584 bait|bait|prey|prey prey|prey|bait|bait BPM3 RAP2-4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19843165 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_11674|UniProt_11665|BIOGRID_3896 prey|bait|bait bait|prey|prey BPM3 At1g76230 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_1803|BIOGRID_11698 bait|prey prey|bait BPM3 At1g79910 MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_5797 prey bait BPM3 U2AF65A MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_9778|UniProt_1865 bait|prey prey|bait BPM3 At1g52540 MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_9573 prey bait BPM3 T12H17.110 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_1993|BIOGRID_11732 prey|bait bait|prey BPM3 BPM5 MI:0018(two hybrid)|MI:0018(two hybrid) 15618422 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_11954|BIOGRID_16589 bait|bait prey|prey BPM3 RAP2-13 MI:0018(two hybrid)|MI:0018(two hybrid) 19843165 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_3895|UniProt_11666 bait|bait prey|prey BPM3 HAT2 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_11019|UniProt_1798 bait|bait prey|prey BPM3 HAT3 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_1799|BIOGRID_12899 bait|bait prey|prey BPM3 ATHB-6 MI:0018(two hybrid) 22172674 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_14949 bait prey BPM3 ATHB-5 MI:0018(two hybrid) 22172674 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_14948 bait prey BPM3 At1g56090 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_6053|BIOGRID_9064 prey|prey bait|bait BPM3 At3g23700 MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_4365 prey bait BPM3 At5g14440 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_3094|BIOGRID_8950 prey|bait bait|prey BPM3 At1g30860 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_1800|BIOGRID_11200 bait|prey prey|bait

PPI - HINT Gene A Gene B PMID Method Quality BPM6 BPM3 15618422 0018 LC BPM3 BPM3 15618422,21798944,21798944 0018,0018,0397 LC,HT BPM3 U2AF65A 21798944,21798944 0018,0397 HT BPM3 T12H17.110 21798944,21798944 0018,0397 HT BPM3 HAT2 21798944,21798944 0018,0397 HT BPM3 HAT3 21798944,21798944 0018,0397 HT BPM3 ATHB-5 22172674 0018 LC BPM3 ATHB-6 22172674 0018 LC BPM3 MS3 15618422 0018 LC BPM3 IAA10 21798944,21798944 0018,0397 HT BPM3 SCE1 21798944,21798944 0018,0397 HT BPM3 Q6NPE4 21798944,21798944 0018,0397 HT BPM3 Q6NQ80 21798944,21798944 0018,0397 HT BPM3 MYB56 25618823 0018 LC BPM3 WRI1 23792371 0018 LC BPM3 RAP2-4 19843165,19843165 0018,0096 LC BPM3 Q8L402 21798944,21798944 0018,0397 HT BPM3 BPM1 15618422 0018 LC BPM3 Q8LB89 21798944,21798944 0018,0397 HT BPM3 Q8LDB7 21798944 0018 HT BPM3 MEBL 21798944,21798944 0018,0397 HT BPM3 Q8VY20 21798944,21798944 0018,0397 HT BPM3 ERF6 21798944,21798944 0018,0397 HT BPM3 FRL4B 21798944,21798944 0018,0397 HT BPM3 ATHB-16 22172674 0018 LC BPM3 Q940T3 21798944 0397 HT BPM3 IMPA1 21798944,21798944 0018,0397 HT BPM3 CUL3B 15618422,15659098 0018,0018 LC BPM3 Q9FNI1 21798944,21798944 0018,0397 HT BPM3 Q9LK47 21798944,21798944 0018,0397 HT BPM3 RAP2-13 19843165 0018 LC BPM3 Q9SGR1 21798944,21798944 0018,0397 HT BPM3 Q9SJU0 21798944,21798944 0018,0397 HT BPM3 F17M5.210 25618823 0018 LC BPM3 FIP37 21798944,21798944 0018,0397 HT BPM3 CUL3A 15659098,15618422 0018,0018 LC BPM3 RAP2-4 19843165,19843165 0018,0096 LC BPM3 CUL3A 15772280,15772280 0004,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q1EBV6 O22286 BPM5 BPM3 0.523 15618422 Q8L402 O22286 Q8L402 BPM3 0.126 21798944 Q8LB89 O22286 Q8LB89 BPM3 0.126 21798944 Q9LM15 O22286 RAP2-13 BPM3 0.523 19843165 O23212 O22286 U2AF65A BPM3 0.286 21798944 O49653 O22286 T12H17.110 BPM3 0.126 21798944 Q940T3 O22286 Q940T3 BPM3 0.126 21798944 P46668 O22286 ATHB-6 BPM3 0.309 22172674 P46667 O22286 ATHB-5 BPM3 0.309 22172674 Q8H1E4 O22286 RAP2-4 BPM3 0.671 19843165 Q6NPE4 O22286 Q6NPE4 BPM3 0.126 21798944 Q6R053 O22286 MYB56 {ECO:0000303|PUBMED:9839469} BPM3 0.523 25618823 Q940J1 O22286 ATHB-16 BPM3 0.309 22172674 Q8VY20 O22286 Q8VY20 BPM3 0.126 21798944 Q9FNI1 O22286 Q9FNI1 BPM3 0.126 21798944 Q9C9L0 O22286 CUL3B BPM3 0.772 15659098,15618422 Q9LK47 O22286 Q9LK47 BPM3 0.126 21798944 Q6X5Y6 O22286 WRI1 BPM3 0.309 23792371 Q6NQ80 O22286 Q6NQ80 BPM3 0.126 21798944 Q8L765 O22286 BPM1 BPM3 0.772 15618422 Q9SJU0 O22286 Q9SJU0 BPM3 0.286 21798944 P46602 O22286 HAT3 BPM3 0.286 21798944 Q8LPT3 O22286 Q8LPT3 BPM3 0.286 21798944 Q940H8 O22286 FRL4B BPM3 0.286 21798944 Q96321 O22286 KAP1 BPM3 0.286 21798944 Q9ZSZ8 O22286 FIP37 BPM3 0.286 21798944 Q9ZVH4 O22286 CUL3A BPM3 0.876 15659098,15772280,15618422 O22286 O22286 BPM3 BPM3 0.702 15618422,21798944 Q93VG8 O22286 Q93VG8 BPM3 0.286 21798944 Q9SGR1 O22286 Q9SGR1 BPM3 0.126 21798944 P46601 O22286 HAT2 BPM3 0.286 21798944 O22286 A1L4W5 BPM3 BPM6 0.309 15618422 Q38828 O22286 IAA10 BPM3 0.286 21798944 Q42551 O22286 SCE1 BPM3 0.286 21798944