PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9LJN8 F4JBB7 two hybrid 19710914 direct interaction X 2 Q9LJN8 F4JBB7 protein complementation assay 19710914 direct interaction X 2 Q9LJN8 Q9ZVW2 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 F4K6W6 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 P59259 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 Q9SZA4 two hybrid 21687678 direct interaction X 2 Q9FHM4 Q9LJN8 affinity chromatography technology 20706207 physical association X 2 Q8LPF1 Q9LJN8 affinity chromatography technology 20706207 physical association X 2 O22806 Q9LJN8 two hybrid 19710914 direct interaction X 2 O22806 Q9LJN8 protein complementation assay 19710914 direct interaction X 2 Q9LJN8 Q9SF16-2 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 Q84WV1 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 F4HRT3 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 Q8GW25 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 Q9M0I4 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 Q9S7I8 two hybrid 21687678 direct interaction X 2 P28769 Q9LJN8 affinity chromatography technology 20706207 physical association X 2 Q9LZR5 Q9LJN8 affinity chromatography technology 20706207 physical association X 2 Q9C5G0-2 Q9LJN8 affinity chromatography technology 20706207 physical association X 2 Q9LJN8 tandem affinity purification 20706207 physical association C 9 Q9LJN8 tandem affinity purification 20706207 association C 6

PPI - HINT Gene A Gene B PMID Method Quality BUBR1 BUB3.1 19710914,25262777,19710914 0090,0018,0018 LC BRK1 BUB3.1 25262777 0018 LC SUF4 BUB3.1 25429892 0018 LC Q9FFG4 BUB3.1 25262777 0018 LC MAP65-3 BUB3.1 25262777 0055 LC BUB3.1 MAD2 19710914,19710914 0090,0018 LC BUB3.1 CDC20-2 21687678 0018 LC BUB3.1 CDC20-1 21687678 0018 LC PDH-E1|ALPHA BUB3.1 20706207 0004 HT CCT1 BUB3.1 20706207,20706207 0004,0676 HT EMB1401 BUB3.1 20706207,20706207 0004,0676 HT CCT3 BUB3.1 20706207,20706207 0004,0676 HT Q8GW25 BUB3.1 20706207,20706207 0004,0676 HT Q8LD15 BUB3.1 20706207,20706207 0004,0676 HT Q8LPF1 BUB3.1 20706207,20706207 0004,0676 HT SUF4 BUB3.1 20706207,20706207 0004,0676 HT MAP65-3 BUB3.1 20706207,20706207 0004,0676 HT Q9FJE8 BUB3.1 20706207,20706207 0004,0676 HT BUB3.1 HDT3 20706207,20706207 0004,0676 HT BUB3.1 Q9M0I4 20706207,20706207 0004,0676 HT BUB3.1 CCT7 20706207,20706207 0004,0676 HT BUB3.1 HEN2 20706207,20706207 0004,0676 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9LJN8 Q9FHM4 BUB3.1 MAP65-3 0.472 20706207,25262777 Q9LJN8 O22806 BUB3.1 BUBR1 0.671 19710914,25262777 Q9LJN8 Q8GW25 BUB3.1 Q8GW25 0.126 20706207 Q9LJN8 Q8LD15 BUB3.1 Q8LD15 0.126 20706207 Q9M0I4 Q9LJN8 Q9M0I4 BUB3.1 0.126 20706207 Q9LJN8 Q84WV1 BUB3.1 Q84WV1 0.236 20706207 Q9LJN8 Q41969 BUB3.1 EMB1401 0.236 20706207 Q9LJN8 P28769 BUB3.1 CCT1 0.236 20706207 Q9LJN8 P59259 BUB3.1 P59259 0.236 20706207 Q9LJN8 Q8LPF1 BUB3.1 Q8LPF1 0.236 20706207 Q9ZVW2 Q9LJN8 HEN2 BUB3.1 0.236 20706207 Q9LZR5 Q9LJN8 HDT3 BUB3.1 0.236 20706207 Q9SF16 Q9LJN8 F26K24.12 BUB3.1 0.236 20706207 Q9LU93 Q9LJN8 MAD2 BUB3.1 0.523 19710914 Q9LJN8 Q9C5G0 BUB3.1 SUF4 0.472 20706207,25429892 Q9LJN8 Q94JY4 BUB3.1 BRK1 0.523 25262777 Q9SZA4 Q9LJN8 CDC20-1 BUB3.1 0.309 21687678 Q9S7I8 Q9LJN8 CDC20-2 BUB3.1 0.309 21687678