PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P49678 P49678 - 9342315 - X 2 P49678 P49677 - 9342315 - X 2 P49678 Q0WV90-1 two hybrid 22065421 direct interaction X 2 P49678 Q94AI7 two hybrid 22065421 direct interaction X 2 P49678 Q38828 two hybrid 21798944 direct interaction X 2 P49678 O24408 two hybrid 21798944 direct interaction X 2 P49678 Q94AI7 two hybrid 21798944 direct interaction X 2 O24407 P49678 two hybrid 21798944 direct interaction X 2 P49678 P49678 two hybrid 9342315 direct interaction X 2 P49678 F4K2T3 two hybrid 22065421 direct interaction X 2 P49678 Q27GK7 two hybrid 22065421 direct interaction X 2 P49678 Q6IDA3 two hybrid 21798944 direct interaction X 2 P49678 F4JLC8 two hybrid 21798944 direct interaction X 2 P49678 Q9XFM0 two hybrid 21798944 direct interaction X 2 Q38825 P49678 two hybrid 21798944 direct interaction X 2 Q5XEN5 P49678 two hybrid 21798944 direct interaction X 2 O24409 P49678 two hybrid 21798944 direct interaction X 2 Q9LRZ0 P49678 two hybrid 22065421 direct interaction X 2 P49678 Q9XED8 two hybrid 21734647 physical association X 2 P49678 Q38828 two hybrid 21734647 physical association X 2 P49678 Q9C966 two hybrid 21734647 physical association X 2 P49678 Q9C5X0 two hybrid 21734647 physical association X 2 P49678 O24408 two hybrid array 21798944 physical association X 2 P49678 Q38828 two hybrid array 21798944 physical association X 2 P49678 Q94AI7 two hybrid array 21798944 physical association X 2 Q96321 P49678 two hybrid array 21798944 physical association X 2 Q9ZSY8 P49678 two hybrid 21734647 physical association X 2 P93024 P49678 two hybrid 21734647 physical association X 2 O24407 P49678 two hybrid 21734647 physical association X 2 O24407 P49678 two hybrid array 21798944 physical association X 2 Q38826 P49678 two hybrid 21734647 physical association X 2 Q38829 P49678 two hybrid array 21798944 physical association X 2 Q9FKM7 P49678 two hybrid 21734647 physical association X 2 Q38827 P49678 two hybrid 21734647 physical association X 2 Q9ZTX8 P49678 two hybrid 21734647 physical association X 2 P49678 Q9FGV1 two hybrid 21734647 physical association X 2 P49678 P49677 two hybrid 21734647 physical association X 2 P49678 P49678 two hybrid 21734647 physical association X 2 P49678 Q38832 two hybrid 21734647 physical association X 2 P49678 Q9XFM0 two hybrid 21734647 physical association X 2 P49678 Q9M1R4 two hybrid 21734647 physical association X 2 P49678 Q6IDA3 two hybrid array 21798944 physical association X 2 P49678 Q9XFM0 two hybrid array 21798944 physical association X 2 P49678 P49678 two hybrid 9342315 physical association X 2 P49678 P49677 two hybrid 9342315 physical association X 2 P49678 P49677 two hybrid 9342315 physical association X 2 P33077 P49678 two hybrid 21734647 physical association X 2 Q38825 P49678 two hybrid array 21798944 physical association X 2 Q5XEN5 P49678 two hybrid array 21798944 physical association X 2 Q8RYC8 P49678 two hybrid 21734647 physical association X 2 O24409 P49678 two hybrid array 21798944 physical association X 2 P93022 P49678 two hybrid 21734647 physical association X 2 O24410 P49678 two hybrid 21734647 physical association X 2 P93830 P49678 two hybrid 21734647 physical association X 2 Q38822 P49678 two hybrid 21734647 physical association X 2 Q38822 P49678 two hybrid array 21798944 physical association X 2 P33078 P49678 two hybrid 21734647 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B IAA20 IAA2 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8410 prey bait IAA2 KAP1 MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_7236 prey bait IAA2 MBD1 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_2475|BIOGRID_8861 bait|bait prey|prey IAA2 ARF7 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8269 prey bait IAA2 ARF5 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8212 prey bait IAA2 At5g52547 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_9394|UniProt_3021 bait|prey prey|bait IAA2 TPL MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944,22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid) BIOGRID_8230|UniProt_6997|BIOGRID_12766 prey|prey|prey bait|bait|bait IAA2 IAA10 MI:0018(two hybrid)|MI:0096(pull down)|MI:0397(two hybrid array) 21734647,21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_8626|UniProt_8411|UniProt_2474 prey|bait|bait bait|prey|prey IAA2 IAA11 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_11821|UniProt_2745 bait|prey prey|bait IAA2 IAA14 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8412 bait prey IAA2 IAA9 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8416 bait prey IAA2 IAA8 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8409 bait prey IAA2 IAA7 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_12025|UniProt_2724 bait|prey prey|bait IAA2 IAA3 MI:0096(pull down)|MI:0397(two hybrid array) 21734647,21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_8406|UniProt_2473 bait|bait prey|prey IAA2 At3g15540 MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_2472 bait prey IAA2 IAA30 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8419 bait prey IAA5 IAA2 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8408 prey bait IAA2 TPR2 MI:0018(two hybrid) 22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_8288 prey bait IAA2 ARF6 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8239 prey bait IAA2 IAA27 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8417 bait prey IAA2 ARF19 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8352 prey bait IAA16 IAA2 MI:0397(two hybrid array)|MI:0096(pull down)|MI:0018(two hybrid) 21734647,21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_1917|UniProt_8414|BIOGRID_8844 bait|prey|bait prey|bait|prey IAA1 IAA2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 21734647,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_8105|UniProt_8106|UniProt_8387 bait|prey|bait prey|bait|prey IAA2 TPR4 MI:0018(two hybrid) 22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_8289 prey bait IAA2 TPR1 MI:0018(two hybrid) 22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_8228 prey bait IAA2 ARF8 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8290 prey bait IAA2 IAA28 MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0096(pull down) 21734647,21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_11833|UniProt_9780|UniProt_8418 bait|prey|bait prey|bait|prey IAA2 TPR3 MI:0018(two hybrid) 22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_8229 prey bait IAA2 IAA34 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8421 bait prey IAA19 IAA2 MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_11882 bait prey IAA2 ARF9 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8312 prey bait IAA4 IAA2 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8407 prey bait IAA2 IAA15 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8413 bait prey IAA2 IAA33 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8420 bait prey IAA18 IAA2 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_2471|BIOGRID_11102 prey|bait bait|prey IAA2 IAA17 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8415 bait prey

PPI - HINT Gene A Gene B PMID Method Quality IAA16 IAA2 21734647,21798944,21798944 0018,0018,0397 LC,HT IAA18 IAA2 21798944,21798944 0018,0397 HT IAA19 IAA2 21798944,21798944 0018,0397 HT IAA20 IAA2 21734647 0018 LC IAA4 IAA2 21734647 0018 LC IAA5 IAA2 21734647 0018 LC IAA1 IAA2 21734647,9342315 0018,0018 LC IAA2 IAA2 21734647,9342315 0018,0018 LC IAA2 ARF7 21734647,25566309 0018,0018 LC IAA2 ARF5 21734647,25566309 0018,0018 LC IAA2 IAA17 21734647 0018 LC IAA2 TPR1 22065421 0018 LC IAA2 TPR4 22065421 0018 LC IAA2 IAA3 21734647,21798944 0018,0397 LC,HT IAA2 IAA7 21798944,21798944 0018,0397 HT IAA2 IAA8 21734647 0018 LC IAA2 IAA9 21734647 0018 LC IAA2 IAA10 21734647,21798944,21798944 0018,0018,0397 LC,HT IAA2 IAA11 21798944,21798944 0018,0397 HT IAA2 IAA14 21734647 0018 LC IAA2 MBD1 21798944,21798944 0018,0397 HT IAA2 Q6IDA3 21798944,21798944 0018,0397 HT IAA2 TPR3 22065421 0018 LC IAA2 ARF19 21734647 0018 LC IAA2 TPL 22065421,21798944,21798944 0018,0018,0397 LC,HT IAA2 IMPA1 21798944 0397 HT IAA2 IAA34 21734647 0018 LC IAA2 IAA15 21734647 0018 LC IAA2 ARF8 21734647,25566309 0018,0018 LC IAA2 IAA33 21734647 0018 LC IAA2 TPR2 22065421 0018 LC IAA2 IAA30 21734647 0018 LC IAA2 ARF9 21734647 0018 LC IAA2 IAA28 21734647,21798944,21798944 0018,0018,0397 LC,HT IAA2 IAA27 21734647 0018 LC IAA2 ARF6 21734647,25566309 0018,0018 LC IAA2 ARF4 25566309 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q0WV90 P49678 TPR1 IAA2 0.183 22065421 Q9LRZ0 P49678 TPR2 IAA2 0.183 22065421 Q9ZTX8 P49678 ARF6 IAA2 0.454 21734647,25566309 Q9ZTX9 P49678 ARF4 IAA2 0.183 25566309 P49678 O24409 IAA2 IAA19 0.183 21798944 Q6IDA3 P49678 Q6IDA3 IAA2 0.126 21798944 Q84JM4 P49678 TPR3 IAA2 0.183 22065421 Q9M1R4 P49678 IAA30 IAA2 0.332 21734647 Q9XED8 P49678 ARF9 IAA2 0.332 21734647 Q9C5X0 P49678 IAA34 IAA2 0.332 21734647 Q38832 P49678 IAA14 IAA2 0.332 21734647 P49678 O24407 IAA2 IAA16 0.523 21734647,21798944 P49678 O24410 IAA2 IAA20 0.332 21734647 Q9ZSY8 P49678 IAA27 IAA2 0.332 21734647 P49678 P33077 IAA2 IAA4 0.332 21734647 P49678 P33078 IAA2 IAA5 0.332 21734647 Q9FKM7 P49678 IAA33 IAA2 0.332 21734647 Q38827 P49678 IAA9 IAA2 0.332 21734647 P93830 P49678 IAA17 IAA2 0.332 21734647 Q38826 P49678 IAA8 IAA2 0.332 21734647 Q8RYC8 P49678 ARF19 IAA2 0.332 21734647 Q38829 P49678 IAA11 IAA2 0.286 21798944 Q5XEN5 P49678 MBD1 IAA2 0.286 21798944 P93022 P49678 ARF7 IAA2 0.454 21734647,25566309 P93024 P49678 ARF5 IAA2 0.454 21734647,25566309 Q94AI7 P49678 TPL IAA2 0.416 21798944,22065421 Q9FGV1 P49678 ARF8 IAA2 0.454 21734647,25566309 P49678 P49678 IAA2 IAA2 0.722 9342315,21734647 Q9XFM0 P49678 IAA28 IAA2 0.523 21734647,21798944 P49678 P49677 IAA2 IAA1 0.539 9342315,21734647 P49678 O24408 IAA2 IAA18 0.286 21798944 Q38822 P49678 IAA3 IAA2 0.416 21734647,21798944 Q38825 P49678 IAA7 IAA2 0.286 21798944 Q38828 P49678 IAA10 IAA2 0.523 21734647,21798944 Q96321 P49678 KAP1 IAA2 0.126 21798944 Q9C966 P49678 IAA15 IAA2 0.183 21734647 Q27GK7 P49678 TPR4 IAA2 0.183 22065421 Q2VWA2 P49678 Q2VWA2 IAA2 0.126 21798944