PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8LEA8 Q9FHW7 - 12795696 - X 2 Q8LEA8 Q39255 - 12795696 - X 2 Q8LEA8 Q9FHW7 two hybrid 23166809 direct interaction X 2 Q8LEA8 Q9SL93 two hybrid 23166809 direct interaction X 2 Q8LEA8 Q9LSX9 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 Q1PEL7 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 Q9FHW7 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 Q9FHW7 two hybrid 11316788 direct interaction X 2 Q8LEA8 Q9FHW7 pull down 11316788 direct interaction X 2 Q8LEA8 Q9FHW7 two hybrid 12795696 direct interaction X 2 Q8LEA8 Q9FHW7 two hybrid 21798944 direct interaction X 2 Q8LEA8 Q39255 two hybrid 23166809 direct interaction X 2 Q8LEA8 Q9LNT9 two hybrid 23166809 direct interaction X 2 Q8LEA8 O49484 two hybrid 23166809 direct interaction X 2 Q8LEA8 O65674 two hybrid 23166809 direct interaction X 2 Q8LEA8 O81057 two hybrid 23166809 direct interaction X 2 Q8LEA8 Q9LNT9 two hybrid 16412087 direct interaction X 2 Q8LEA8 O49484 two hybrid 16412087 direct interaction X 2 Q8LEA8 O81057 two hybrid 16412087 direct interaction X 2 Q8LEA8 Q9LNT9 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 O49484 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 O81057 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 B9DGE3 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 Q39255 two hybrid 12795696 direct interaction X 2 Q8LEA8 Q39255 two hybrid 16333572 direct interaction X 2 Q8LEA8 Q39255 protein complementation assay 16333572 direct interaction X 2 Q8LEA8 Q39255 two hybrid 21798944 direct interaction X 2 Q8LEA8 Q39255 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 Q39255 two hybrid 16412087 direct interaction X 2 Q8LEA8 Q39255 pull down 11316788 direct interaction X 2 Q8LEA8 Q39255 two hybrid 11316788 direct interaction X 2 Q9M1X5 Q8LEA8 two hybrid 23166809 direct interaction X 2 Q9M1X5 Q8LEA8 two hybrid 16412087 direct interaction X 2 Q9M1X5 Q8LEA8 fluorescent resonance energy transfer 16412087 direct interaction X 2 Q8LEA8 protein three hybrid 16412087 physical association C 3 Q8LEA8 protein three hybrid 16412087 physical association C 3 Q8LEA8 protein three hybrid 16412087 physical association C 3 Q8LEA8 Q9FHW7 two hybrid 12795696 physical association X 2 Q8LEA8 Q9FHW7 two hybrid 16412087 physical association X 2 Q8LEA8 Q9FHW7 bimolecular fluorescence complementation 16412087 physical association X 2 Q8LEA8 Q9LSX9 bimolecular fluorescence complementation 16412087 physical association X 2 Q8LEA8 Q1PEL7 bimolecular fluorescence complementation 16412087 physical association X 2 Q8LEA8 Q9FHW7 two hybrid array 21798944 physical association X 2 Q8LEA8 protein three hybrid 16412087 physical association C 3 Q8LEA8 Q39255 two hybrid 12795696 physical association X 2 Q8LEA8 Q39255 two hybrid 16412087 physical association X 2 Q8LEA8 O81057 two hybrid 16412087 physical association X 2 Q8LEA8 Q9LNT9 bimolecular fluorescence complementation 16412087 physical association X 2 Q8LEA8 Q9LNT9 two hybrid 16412087 physical association X 2 Q8LEA8 O49484 bimolecular fluorescence complementation 16412087 physical association X 2 Q8LEA8 O81057 bimolecular fluorescence complementation 16412087 physical association X 2 Q8LEA8 Q39255 bimolecular fluorescence complementation 16412087 physical association X 2 Q8LEA8 O49484 two hybrid 16412087 physical association X 2 Q8LEA8 Q39255 two hybrid array 21798944 physical association X 2 Q8LEA8 Q9LNT9 two hybrid array 21798944 physical association X 2 Q9M1X5 Q8LEA8 bimolecular fluorescence complementation 16412087 physical association X 2 Q9M1X5 Q8LEA8 two hybrid 16412087 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B EID1 ASK3 MI:0018(two hybrid) 23166809 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_19449 bait prey EID1 ASK9 MI:0018(two hybrid)|MI:0018(two hybrid) 16412087 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_417|UniProt_12354 bait|neutral component prey|neutral component EID1 ASK13 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16412087,23166809 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(biogrid)|(biogrid)|(biogrid) UniProt_12356|UniProt_12338|BIOGRID_19453|BIOGRID_419|BIOGRID_403 neutral component|bait|bait|bait|bait neutral component|prey|prey|prey|prey ASK11 EID1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16412087,23166809 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(biogrid)|(intact)|(biogrid)|(biogrid) UniProt_12363|UniProt_12355|BIOGRID_418|UniProt_12337|BIOGRID_402|BIOGRID_19451 neutral component|neutral component|prey|prey|prey|prey neutral component|neutral component|bait|bait|bait|bait ASK14 EID1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16412087,23166809 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|(intact) BIOGRID_19454|UniProt_12357|BIOGRID_404|BIOGRID_420|UniProt_12339|UniProt_12364 prey|neutral component|prey|prey|prey|neutral component bait|neutral component|bait|bait|bait|neutral component EID1 ASK4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid) 16412087,21798944,23166809 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact) UniProt_12336|UniProt_12353|BIOGRID_416|BIOGRID_401|BIOGRID_19450|UniProt_6091|UniProt_12362 bait|neutral component|bait|bait|bait|bait|neutral component prey|neutral component|prey|prey|prey|prey|neutral component EID1 SKP1B MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid) 11316788,12795696,16412087,21798944,23166809 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(biogrid) BIOGRID_2258|UniProt_12335|BIOGRID_19448|BIOGRID_422|BIOGRID_9949|BIOGRID_502|UniProt_12352|UniProt_16933|UniProt_3768|BIOGRID_501 prey|bait|bait|bait|bait|bait|neutral component|prey|prey|bait bait|prey|prey|prey|prey|prey|neutral component|bait|bait|prey ASK15 EID1 MI:0018(two hybrid)|MI:0018(two hybrid) 16412087 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_12358|BIOGRID_421 neutral component|prey neutral component|bait ASK12 EID1 MI:0018(two hybrid) 23166809 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_19452 prey bait SKP1A EID1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid) 11316788,12795696,16333572,16412087,21798944,23166809 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_2233|BIOGRID_19447|BIOGRID_15022|BIOGRID_15021|BIOGRID_15020|BIOGRID_3118|BIOGRID_3117|BIOGRID_15018|BIOGRID_12498|UniProt_12360|UniProt_12334|UniProt_2834|UniProt_16907|UniProt_12361 bait|prey|prey|prey|prey|prey|prey|prey|bait|neutral component|prey|bait|bait|neutral component prey|bait|bait|bait|bait|bait|bait|bait|prey|neutral component|bait|prey|prey|neutral component

PPI - HINT Gene A Gene B PMID Method Quality ASK11 EID1 16412087,16412087,16412087,23166809,16412087 0018,0437,0809,0018,0055 LC ASK12 EID1 23166809 0018 LC ASK14 EID1 16412087,16412087,16412087,23166809,16412087 0018,0437,0809,0018,0055 LC ASK3 EID1 23166809 0018 LC ASK15 EID1 16412087,16412087 0809,0055 LC ASK9 EID1 16412087,16412087 0809,0055 LC SKP1A EID1 16333572,23166809,16412087,11316788,16412087,11316788,12795696,16412087,16333572,21798944,21798944 0018,0018,0055,0096,0018,0018,0018,0809,0090,0018,0397 LC,HT EID1 CUL1 16412087,16412087 0437,0055 LC EID1 SKP1B 23166809,16412087,11316788,16412087,11316788,12795696,16412087,21798944,21798944 0018,0055,0096,0018,0018,0018,0809,0018,0397 LC,HT EID1 ASK4 16412087,23166809,16412087,16412087,16412087,21798944 0437,0018,0055,0018,0809,0397 LC,HT EID1 ASK13 16412087,16412087,23166809,16412087 0018,0809,0018,0055 LC SKP1A EID1 11316788,11316788 0096,0018 LC EID1 SKP1B 11316788,11316788 0096,0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8LEA8 Q1PEL7 EID1 ASK15 0.286 16412087 Q8LEA8 O65674 EID1 ASK12 0.183 23166809 Q9SL93 Q8LEA8 ASK3 EID1 0.183 23166809 Q9M1X5 Q8LEA8 ASK13 EID1 0.61 16412087,23166809 Q9LSX9 Q8LEA8 ASK9 EID1 0.286 16412087 Q9FHW7 Q8LEA8 SKP1B EID1 0.891 12795696,21798944,16412087,23166809,11316788 Q8LEA8 O49484 EID1 ASK11 0.659 16412087,23166809 Q8LEA8 O81057 EID1 ASK14 0.659 16412087,23166809 Q9LNT9 Q8LEA8 ASK4 EID1 0.702 21798944,16412087,23166809 Q8LEA8 Q39255 EID1 SKP1A 0.958 12795696,16333572,21798944,23166809,11316788,16412087 Q94AH6 Q8LEA8 CUL1 EID1 0.286 16412087