PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P33077 P49677 - 9342315 - X 2 O24407 P49677 - 9342315 - X 2 P49677 - 9342315 - X 2 P49677 P49677 - 9342315 - X 2 P49677 - 9342315 - X 2 P49677 - 9342315 - X 2 Q8RYC8 P49677 - 9342315 - X 2 P49677 - 9342315 - X 2 P49678 P49677 - 9342315 - X 2 P49677 - 9342315 - X 2 P49677 O24408 - 9342315 - X 2 P93830 P49677 - 9342315 - X 2 Q38822 P49677 - 9342315 - X 2 P93024 P49677 protein complementation assay 22096563 direct interaction X 2 P49677 F4K2T3 two hybrid 22065421 direct interaction X 2 P49677 Q9XFM0 two hybrid 21798944 direct interaction X 2 O24409 P49677 two hybrid 21798944 direct interaction X 2 Q9LRZ0 P49677 two hybrid 22065421 direct interaction X 2 P49677 Q570C0 pull down 15546359 direct interaction X 2 P49677 Q94AI7 two hybrid 22065421 direct interaction X 2 P49677 Q0WV90-1 two hybrid 22065421 direct interaction X 2 P49677 Q38824 two hybrid 21798944 direct interaction X 2 P49677 Q94AI7 two hybrid 21798944 direct interaction X 2 P49677 O24408 two hybrid 21798944 direct interaction X 2 Q38822 P49677 two hybrid 21798944 direct interaction X 2 F4J7K1 P49677 two hybrid 21798944 direct interaction X 2 P93022 P49677 pull down 24362628 physical association X 2 Q9ZSY8 P49677 two hybrid 21734647 physical association X 2 Q9ZSY8 P49677 two hybrid array 21798944 physical association X 2 P33077 P49677 two hybrid 21734647 physical association X 2 P33077 P49677 two hybrid 9342315 physical association X 2 P93024 P49677 two hybrid 14729917 physical association X 2 P93024 P49677 two hybrid 21734647 physical association X 2 P93024 P49677 split firefly luciferase complementation 22096563 physical association X 2 P93024 P49677 two hybrid 9342315 physical association X 2 O24407 P49677 two hybrid 21734647 physical association X 2 O24407 P49677 two hybrid array 21798944 physical association X 2 O24407 P49677 two hybrid 9342315 physical association X 2 Q38826 P49677 two hybrid 21734647 physical association X 2 Q38826 P49677 two hybrid 9342315 physical association X 2 P49677 P49677 two hybrid 14729917 physical association X 2 P49677 Q9XED8 two hybrid 21734647 physical association X 2 P49677 P49677 two hybrid 21734647 physical association X 2 P49677 Q38832 two hybrid 21734647 physical association X 2 P49677 Q9C966 two hybrid 21734647 physical association X 2 P49677 Q9XFM0 two hybrid 21734647 physical association X 2 P49677 Q9C5X0 two hybrid 21734647 physical association X 2 P49677 P49677 pull down 21798944 direct interaction X 2 P49677 P49677 two hybrid array 21798944 physical association X 2 P49677 Q9XFM0 two hybrid array 21798944 physical association X 2 P49677 P49677 two hybrid 9342315 physical association X 2 Q8RYC8 P49677 two hybrid 21734647 physical association X 2 Q8RYC8 P49677 two hybrid 9342315 physical association X 2 O24409 P49677 two hybrid 21734647 physical association X 2 O24409 P49677 two hybrid array 21798944 physical association X 2 O24409 P49677 two hybrid 9342315 physical association X 2 P93022 P49677 two hybrid 14729917 physical association X 2 P93022 P49677 two hybrid 21734647 physical association X 2 P93022 P49677 two hybrid 9342315 physical association X 2 O24410 P49677 two hybrid 9342315 physical association X 2 Q38827 P49677 two hybrid 21734647 physical association X 2 Q38827 P49677 two hybrid 9342315 physical association X 2 Q9LV27 P49677 two hybrid array 21798944 physical association X 2 Q9ZTX8 P49677 two hybrid 21734647 physical association X 2 P33078 P49677 two hybrid 21734647 physical association X 2 P49678 P49677 two hybrid 21734647 physical association X 2 P49678 P49677 two hybrid 9342315 physical association X 2 P49678 P49677 two hybrid 9342315 physical association X 2 Q38825 P49677 two hybrid 21734647 physical association X 2 P49679 P49677 two hybrid 9342315 physical association X 2 P49679 P49677 two hybrid 9342315 physical association X 2 P49679 P49677 cross-linking study 9342315 direct interaction X 2 P49677 Q9FGV1 two hybrid 14729917 physical association X 2 P49677 Q570C0 pull down 15546359 physical association X 2 P49677 Q9FGV1 two hybrid 21734647 physical association X 2 P49677 Q84WU6 two hybrid 21734647 physical association X 2 P49677 O24408 two hybrid 21734647 physical association X 2 P49677 Q9M1R4 two hybrid 21734647 physical association X 2 P49677 O24408 two hybrid array 21798944 physical association X 2 P49677 Q38824 two hybrid array 21798944 physical association X 2 P49677 Q94AI7 two hybrid array 21798944 physical association X 2 P49677 O24408 two hybrid array 21798944 physical association X 2 P93830 P49677 two hybrid 21734647 physical association X 2 P93830 P49677 two hybrid 9342315 physical association X 2 Q38822 P49677 two hybrid 21734647 physical association X 2 Q38822 P49677 two hybrid array 21798944 physical association X 2 Q38822 P49677 two hybrid 9342315 physical association X 2 D3K0M2 P49677 two hybrid 21734647 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B IAA20 IAA1 MI:0018(two hybrid) 9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8098 prey bait IAA1 IAA28 MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0096(pull down) 21734647,21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_11832|UniProt_9779|UniProt_8401 bait|prey|bait prey|bait|prey IAA1 ARF17 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8348 prey bait IAA1 ARF9 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8311 prey bait IAA1 IAA15 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8395 bait prey IAA1 IAA31 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8397 bait prey IAA1 At3g15540 MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_2467 bait prey IAA1 ARF19 MI:0018(two hybrid)|MI:0096(pull down) 21734647,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_8100|UniProt_8351 bait|prey prey|bait IAA1 IAA7 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8391 bait prey IAA1 IAA8 MI:0018(two hybrid)|MI:0096(pull down) 21734647,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_8093|UniProt_8392 bait|bait null|prey IAA1 IAA6 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_2469|BIOGRID_8700 bait|prey prey|bait IAA1 IAA3 MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0096(pull down) 21734647,21798944,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_2468|UniProt_8091|UniProt_8388 bait|bait|bait prey|prey|prey IAA1 IAA14 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8394 bait prey IAA1 IAA9 MI:0018(two hybrid)|MI:0096(pull down) 21734647,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_8094|UniProt_8393 bait|bait prey|prey IAA1 IAA30 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8402 bait prey IAA1 ARF8 MI:0096(pull down)|MI:0018(two hybrid) 14729917,21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_8289|UniProt_16422 prey|prey bait|bait IAA5 IAA1 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8383 prey bait IAA1 ARF6 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8244 prey bait IAA1 IAA3 MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_12730 prey bait IAA1 IAA27 MI:0397(two hybrid array)|MI:0096(pull down) 21734647,21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_9877|UniProt_8400 prey|bait bait|prey IAA1 TPL MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid) 21798944,22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(biogrid)|(biogrid) UniProt_2470|BIOGRID_8299|BIOGRID_9030 bait|prey|prey prey|bait|bait IAA1 TPR2 MI:0018(two hybrid) 22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_8301 prey bait IAA16 IAA1 MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0096(pull down) 21734647,21798944,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_1916|UniProt_8095|UniProt_8396 bait|prey|prey prey|bait|bait IAA1 IAA2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 21734647,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_8105|UniProt_8106|UniProt_8387 bait|prey|bait prey|bait|prey IAA1 At3g18140 MI:0018(two hybrid)|MI:0397(two hybrid array) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_11649|UniProt_4650 prey|prey bait|bait IAA1 IAA17 MI:0018(two hybrid)|MI:0096(pull down) 21734647,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_8096|UniProt_8403 bait|bait prey|prey IAA1 TPR1 MI:0018(two hybrid) 22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_8300 prey bait IAA19 IAA1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 21734647,21798944,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_8701|UniProt_8097|UniProt_8399 bait|prey|prey prey|bait|bait IAA4 IAA1 MI:0018(two hybrid)|MI:0096(pull down) 21734647,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_8092|UniProt_8389 prey|prey bait|bait IAA1 IAA34 MI:0096(pull down) 21734647 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_8404 bait prey IAA1 ARF7 MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 14729917,21734647,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_8268|UniProt_16418|UniProt_8099 prey|prey|bait bait|bait|prey IAA1 TIR1 MI:0096(pull down)|MI:0096(pull down) 15546359 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_15946|BIOGRID_2582 bait|bait prey|prey IAA1 ARF5 MI:0018(two hybrid)|MI:0018(two hybrid)|-|MI:0096(pull down)|MI:0090(protein complementation assay) 14729917,21734647,22096563,9342315 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_16427|UniProt_8101|UniProt_8973|UniProt_8211|BIOGRID_14979 prey|bait|neutral component|prey|bait bait|prey|neutral component|bait|prey IAA1 TPR3 MI:0018(two hybrid) 22065421 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_8302 prey bait IAA18 IAA1 MI:0397(two hybrid array)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0096(pull down) 21734647,21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(intact) UniProt_1923|UniProt_2465|BIOGRID_11622|UniProt_8398 bait|prey|bait|prey prey|bait|prey|bait

PPI - HINT Gene A Gene B PMID Method Quality B9DFE0 IAA1 21798944 0018 HT IAA16 IAA1 21734647,21798944,9342315 0018,0397,0018 LC,HT IAA18 IAA1 21734647,21798944,21798944,9342315 0018,0018,0397,0018 LC,HT IAA19 IAA1 21734647,21798944,21798944,9342315 0018,0018,0397,0018 LC,HT IAA20 IAA1 9342315 0018 LC IAA4 IAA1 21734647,9342315 0018,0018 LC IAA5 IAA1 21734647 0018 LC IAA1 IAA1 9342315,14729917,21798944,9342315,25611322,21734647,9342315,21798944 0071,0018,0096,0018,0090,0018,0030,0397 LC,HT IAA1 IAA2 21734647,9342315 0018,0018 LC IAA1 ARF7 9342315,21734647,14729917,25566309 0018,0018,0018,0018 LC IAA1 ARF5 14729917,9342315,22096563,21734647,22096563,25566309 0018,0018,1204,0018,0090,0018 LC IAA1 IAA17 21734647,9342315 0018,0018 LC IAA1 TPR1 22065421 0018 LC IAA1 IAA3 21734647,21798944,21798944,9342315 0018,0018,0397,0018 LC,HT IAA1 IAA6 21798944,21798944 0018,0397 HT IAA1 IAA7 21734647,25888615 0018,0018 LC IAA1 IAA8 9342315,21734647 0018,0018 LC IAA1 IAA9 9342315,21734647 0018,0018 LC IAA1 IAA14 21734647 0018 LC IAA1 TIR1 25888615 0018 LC IAA1 TPR3 22065421 0018 LC IAA1 ARF17 21734647 0018 LC IAA1 IAA31 21734647 0018 LC IAA1 ARF19 21734647,9342315 0018,0018 LC IAA1 TPL 22065421,21798944,21798944 0018,0018,0397 LC,HT IAA1 IAA34 21734647 0018 LC IAA1 IAA15 21734647 0018 LC IAA1 ARF8 21734647,14729917,25566309 0018,0018,0018 LC IAA1 TPR2 22065421 0018 LC IAA1 Q9LV27 21798944,21798944 0018,0397 HT IAA1 IAA30 21734647 0018 LC IAA1 ARF10 25566309 0018 LC IAA1 ARF9 21734647 0018 LC IAA1 IAA28 21734647,21798944,21798944 0018,0018,0397 LC,HT IAA1 IAA27 21734647,21798944 0018,0397 LC,HT IAA1 ARF6 21734647,25566309 0018,0018 LC IAA1 ARF4 25566309 0018 LC IAA1 IAA1 21798944,21798944 0096,0397 LC IAA1 ARF7 24362628 0096 LC IAA1 TIR1 15546359 0096 LC IAA1 UBQ10 25888615 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q0WV90 P49677 TPR1 IAA1 0.183 22065421 Q9LRZ0 P49677 TPR2 IAA1 0.183 22065421 Q9ZTX9 P49677 ARF4 IAA1 0.183 25566309 Q84JM4 P49677 TPR3 IAA1 0.183 22065421 Q9M1R4 P49677 IAA30 IAA1 0.332 21734647 Q9XFM0 P49677 IAA28 IAA1 0.523 21734647,21798944 Q9C5X0 P49677 IAA34 IAA1 0.332 21734647 Q38824 P49677 IAA6 IAA1 0.286 21798944 Q38832 P49677 IAA14 IAA1 0.332 21734647 P49677 O24409 IAA1 IAA19 0.623 9342315,21734647,21798944 Q9XED8 P49677 ARF9 IAA1 0.332 21734647 P93022 P49677 ARF7 IAA1 0.82 25566309,14729917,21734647,9342315 P49677 P33078 IAA1 IAA5 0.332 21734647 Q8H174 P49677 IAA31 IAA1 0.332 21734647 Q84WU6 P49677 ARF17 IAA1 0.332 21734647 Q9ZSY8 P49677 IAA27 IAA1 0.416 21734647,21798944 Q9ZTX8 P49677 ARF6 IAA1 0.454 21734647,25566309 Q8RYC8 P49677 ARF19 IAA1 0.539 9342315,21734647 P49677 P33077 IAA1 IAA4 0.539 9342315,21734647 P93024 P49677 ARF5 IAA1 0.872 22096563,25566309,14729917,21734647,9342315 P93830 P49677 IAA17 IAA1 0.539 9342315,21734647 Q38826 P49677 IAA8 IAA1 0.539 9342315,21734647 P49677 O24407 IAA1 IAA16 0.597 9342315,21734647,21798944 P49677 P49677 IAA1 IAA1 0.917 25611322,14729917,21734647,21798944,9342315 Q9C966 P49677 IAA15 IAA1 0.183 21734647 Q9SKN5 P49677 ARF10 IAA1 0.183 25566309 P49677 O24408 IAA1 IAA18 0.583 21734647,21798944 P49677 O24410 IAA1 IAA20 0.309 9342315 P49678 P49677 IAA2 IAA1 0.539 9342315,21734647 Q38827 P49677 IAA9 IAA1 0.539 9342315,21734647 Q3E7T8 P49677 UBQ14 IAA1 0.21 25888615 Q570C0 P49677 TIR1 IAA1 0.623 25888615,15546359 Q8H159 P49677 UBQ10 IAA1 0.21 25888615 Q94AI7 P49677 TPL IAA1 0.416 21798944,22065421 Q9FGV1 P49677 ARF8 IAA1 0.74 25566309,14729917,21734647 Q9LV27 P49677 Q9LV27 IAA1 0.126 21798944 P49679 P49677 IAA4/5 IAA1 0.671 9342315 Q2VWA2 P49677 Q2VWA2 IAA1 0.126 21798944 Q38822 P49677 IAA3 IAA1 0.671 9342315,21734647,21798944 Q38825 P49677 IAA7 IAA1 0.539 21734647,25888615