PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q710E8 B7U179 pull down 18818695 direct interaction X 2 Q710E8 B7U179 pull down 18818695 direct interaction X 2 Q710E8 B7U179 affinity chromatography technology 18818695 physical association X 2 Q710E8 Q9ZRZ8 affinity chromatography technology 20706207 physical association X 2 Q710E8 F4K6W6 affinity chromatography technology 20706207 physical association X 2 Q710E8 Q9C5Z1 affinity chromatography technology 20706207 physical association X 2 Q710E8 B7U179 pull down 18818695 direct interaction X 2 Q710E8 B7U179 two hybrid 18818695 physical association X 2 Q710E8 B7U179 two hybrid 18818695 physical association X 2 Q710E8 B7U179 two hybrid 18818695 physical association X 2 Q710E8 B7U179 pull down 18818695 direct interaction X 2 Q710E8 pull down 18818695 association C 5 Q710E8 tandem affinity purification 20706207 association C 5 Q710E8 pull down 18818695 physical association C 3 Q710E8 pull down 18818695 physical association C 3 Q710E8 anti bait coimmunoprecipitation 18818695 association C 4 Q710E8 pull down 18818695 physical association C 3

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B ORC1A RH28 MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_5515|UniProt_9246 bait|bait prey|prey ORC1A ABAP1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18818695 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|(intact)|(intact) UniProt_11686|UniProt_11687|UniProt_11696|BIOGRID_4027|UniProt_11688|UniProt_11697|BIOGRID_4033|BIOGRID_4032|UniProt_11704|UniProt_11693|UniProt_11699 bait|bait|prey|prey|prey|bait|prey|bait|bait|prey|bait prey|prey|bait|bait|bait|prey|bait|prey|prey|bait|prey EMB1401 ORC1A MI:0090(protein complementation assay)|MI:0676(tandem affinity purification) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_5516|UniProt_9246 prey|prey bait|bait ORC1A TIF3B1 MI:0676(tandem affinity purification)|MI:0090(protein complementation assay) 20706207 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_9246|BIOGRID_5517 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality ABAP1 ORC1A 18818695,18818695,18818695,18818695 0096,0006,0004,0018 LC ABAP1 ORC1A 18818695,18818695,18818695,18818695 0096,0006,0004,0018 LC PDH-E1|ALPHA ORC1A 20706207 0004 HT EMB1401 ORC1A 20706207,20706207 0004,0676 HT ORC3 ORC1A 18818695 0096 LC ORC1A TIF3B1 20706207,20706207 0004,0676 HT ORC1A TCP24 18818695 0096 LC ORC1A CDT1B 18818695 0096 LC ORC1A F7O18.10 20706207 0676 HT ORC1A RH28 20706207,20706207 0004,0676 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q710E8 Q6E7H0 ORC1A ORC3 0.21 18818695 Q9SR12 Q710E8 F7O18.10 ORC1A 0.126 20706207 Q9C5Z1 Q710E8 TIF3B1 ORC1A 0.236 20706207 Q710E8 Q41969 ORC1A EMB1401 0.236 20706207 Q9ZRZ8 Q710E8 RH28 ORC1A 0.236 20706207 Q9M1S9 Q710E8 CDT1B ORC1A 0.376 18818695 Q710E8 B7U179 ORC1A ABAP1 0.872 18818695 Q9C758 Q710E8 TCP24 ORC1A 0.507 18818695