PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q5ICL9 A1A6J5 two hybrid 15634206 direct interaction X 2 Q5ICL9 Q39163 two hybrid 15634206 direct interaction X 2 Q5ICL9 Q39163 two hybrid 17076807 direct interaction X 2 Q5ICL9 A1A6J5 two hybrid 17076807 direct interaction X 2 Q147Q9 Q5ICL9 two hybrid 15634206 direct interaction X 2 Q147Q9 Q5ICL9 two hybrid 17076807 direct interaction X 2 Q5ICL9 A8MQK5 two hybrid 17076807 direct interaction X 2 B2BDR5 Q5ICL9 two hybrid 15634206 direct interaction X 2 B2BDR5 Q5ICL9 two hybrid 17076807 direct interaction X 2 Q9ZVH4 Q5ICL9 pull down 22699612 physical association X 2 Q5ICL9 pull down 22699612 - C 3 Q8L746 Q5ICL9 two hybrid 22699612 direct interaction X 2 Q8L746 Q5ICL9 two hybrid 22699612 direct interaction X 2 P93002 Q5ICL9 two hybrid 22699612 direct interaction X 2 P93002 Q5ICL9 two hybrid 22699612 direct interaction X 2 P93002 Q5ICL9 pull down 22699612 direct interaction X 2 Q5ICL9 Q5ICL9 molecular sieving 22699612 direct interaction Y 1 Q5ICL9 Q5ICL9 two hybrid 22699612 direct interaction Y 1 Q5ICL9 Q39163 two hybrid 15634206 physical association X 2 Q5ICL9 A1A6J5 two hybrid 15634206 physical association X 2 Q93ZE2 Q5ICL9 two hybrid 15634206 physical association X 2 Q147Q9 Q5ICL9 two hybrid 15634206 physical association X 2 B2BDR5 Q5ICL9 two hybrid 15634206 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TGA6 NPR4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15634206,17076807 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid) BIOGRID_2588|UniProt_13480|BIOGRID_3092 prey|prey|prey bait|bait|bait TGA1 NPR4 MI:0018(two hybrid) 17076807 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_3097 prey bait NPR4 TGA7 MI:0018(two hybrid) 15634206 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_13481 bait prey TGA5 NPR4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15634206,17076807 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid) BIOGRID_2589|UniProt_13479|BIOGRID_3091 prey|prey|prey bait|bait|bait TGA3 NPR4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15634206,17076807 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(intact) BIOGRID_2587|BIOGRID_3090|UniProt_13478 prey|prey|prey bait|bait|bait TGA2 NPR4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15634206,17076807 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(intact) BIOGRID_2586|BIOGRID_3089|UniProt_13477 prey|prey|prey bait|bait|bait

PPI - HINT Gene A Gene B PMID Method Quality TGA2 NPR4 15634206,17076807 0018,0018 LC NPR1 NPR4 22699612,22699612 0096,0018 LC TGA6 NPR4 15634206,17076807 0018,0018 LC TGA5 NPR4 15634206,17076807 0018,0018 LC TGA3 NPR4 15634206,17076807 0018,0018 LC TGA1 NPR4 17076807 0018 LC NPR4 NPR4 22699612,22699612 0071,0018 LC NPR4 NPR3 22699612 0018 LC NPR4 TGA7 15634206 0018 LC NPR1 NPR4 22699612,22699612 0096,0018 LC NPR4 CUL3A 22699612 0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5ICL9 Q39237 NPR4 TGA1 0.309 17076807 Q93ZE2 Q5ICL9 TGA7 NPR4 0.309 15634206 Q5ICL9 P43273 NPR4 TGA2 0.671 17076807,15634206 Q5ICL9 Q39140 NPR4 TGA6 0.671 17076807,15634206 Q5ICL9 Q39163 NPR4 TGA5 0.671 17076807,15634206 Q5ICL9 Q39234 NPR4 TGA3 0.671 17076807,15634206