PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9M548 Q1EC66 pull down 16007098 direct interaction X 2 Q9M548 Q1EC66 pull down 19620964 direct interaction X 2 Q9M548 Q9LUJ3 affinity chromatography technology 20410883 physical association X 2 Q9M548 Q9LUJ3 affinity chromatography technology 20410883 physical association X 2 Q9M548 P62987 pull down 16007098 direct interaction X 2 Q9M548 Q9LUJ3 anti tag coimmunoprecipitation 20410883 physical association X 2 Q9M548 Q9LUJ3 anti bait coimmunoprecipitation 20410883 physical association X 2 Q9M548 anti tag coimmunoprecipitation 24855943 association C 8 Q9M548 Q7XA66 fluorescence technology 23524848 colocalization X 2 Q9M548 Q9ZVD5 anti tag coimmunoprecipitation 24855943 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBQ3 DRM2 MI:0096(pull down) 19620964 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_7837 prey bait DRM2 RDM1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20410883 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_4626|BIOGRID_4623 prey|bait bait|prey At1g49590 DRM2 MI:0007(anti tag coimmunoprecipitation) 23524848 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0403(colocalization) (intact) UniProt_9574 unspecified role unspecified role

PPI - HINT Gene A Gene B PMID Method Quality Q7XA66 DRM2 23524848 0051 LC MSI4 DRM2 24855943 0007 LC H2B DRM2 24855943 0007 LC UBQ3 DRM2 16007098,19620964 0096,0096 LC SKP1A DRM2 24855943 0007 LC AGO9 DRM2 24855943 0007 LC TPR2 DRM2 24855943 0007 LC RDM1 DRM2 20410883,20410883,20410883 0006,0007,0004 LC HDT3 DRM2 24855943 0007 LC DRM2 AGO4 24855943 0007 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9M548 Q9LUJ3 DRM2 RDM1 0.376 20410883 Q9M548 O22607 DRM2 MSI4 0.21 24855943 Q9M548 O23629 DRM2 H2B 0.21 24855943 Q9M548 Q39255 DRM2 SKP1A 0.21 24855943 Q9M548 Q7XA66 DRM2 Q7XA66 0.126 23524848 Q9M548 Q84VQ0 DRM2 AGO9 0.21 24855943 Q9M548 Q9LRZ0 DRM2 TPR2 0.21 24855943 Q9M548 Q9LZR5 DRM2 HDT3 0.21 24855943 Q9ZVD5 Q9M548 AGO4 DRM2 0.376 24855943 Q9M548 Q1EC66 DRM2 UBQ3 0.523 19620964,16007098