PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q940X7 molecular sieving 16844902 physical association C 5 Q940X7 anti tag coimmunoprecipitation 15447654 association C 4 B9DGE3 Q940X7 pull down 12215511 physical association X 2 B9DGE3 Q940X7 two hybrid 12381738 physical association X 2 B9DGE3 Q940X7 pull down 12381738 physical association X 2 B9DGE3 Q940X7 anti bait coimmunoprecipitation 12839993 physical association X 2 B9DGE3 Q940X7 two hybrid 15659098 physical association X 2 B9DGE3 Q940X7 two hybrid 15749712 physical association X 2 Q940X7 Q570C0 pull down 12215511 physical association X 2 Q940X7 Q9ZNU6 pull down 16792691 physical association X 2 Q9C9L0 Q940X7 two hybrid 15618422 physical association X 2 Q9C9L0 Q940X7 pull down 15618422 physical association X 2 Q9C9L0 Q940X7 two hybrid 15659098 physical association X 2 Q940X7 anti tag coimmunoprecipitation 12381738 association C 3 Q940X7 Q8LGH4 two hybrid 12381738 physical association X 2 Q940X7 Q9SDY5 pull down 12682009 physical association X 2 Q940X7 Q9SDY5 pull down 12682009 physical association X 2 Q940X7 Q9ZVH4 two hybrid 15618422 physical association X 2 Q940X7 Q9ZVH4 pull down 15618422 physical association X 2 Q940X7 Q9ZVH4 two hybrid 15659098 physical association X 2 Q940X7 Q8LGH4 two hybrid 16792691 physical association X 2 Q940X7 Q9ZVH4 two hybrid 16792691 physical association X 2 Q940X7 Q8LGH4 two hybrid 16844902 physical association X 2 Q940X7 Q8LGH4 anti tag coimmunoprecipitation 16844902 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RBX1A RCE1 MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 12682009 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(biogrid)|(biogrid) UniProt_17493|UniProt_17492|BIOGRID_2227|BIOGRID_2228 prey|prey|prey|bait bait|bait|bait|prey RBX1A CUL3B MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15618422,15659098,15749712 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|(intact)|(biogrid)|(intact)|(biogrid) BIOGRID_16591|UniProt_11957|UniProt_12196|BIOGRID_5832|UniProt_11961|BIOGRID_2598 prey|prey|prey|prey|bait|prey bait|bait|bait|bait|prey|bait TIR1 RBX1A MI:0096(pull down) 12215511 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (intact) UniProt_17798 prey bait RBX1A SKP1B MI:0018(two hybrid)|MI:0018(two hybrid) 12381738 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_2141|UniProt_16666 prey|prey bait|bait RBX1A TIR MI:0096(pull down) 12215511 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_2123 bait prey CUL4 RBX1A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 12381738,16792691,16844902 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(biogrid)|(intact) BIOGRID_784|BIOGRID_880|UniProt_12770|BIOGRID_787|UniProt_12761|UniProt_12484|UniProt_16664|BIOGRID_2139|UniProt_12778 prey|bait|prey|prey|prey|null|prey|prey|neutral component bait|prey|bait|bait|bait|prey|bait|bait|neutral component RBX1A CUL3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15618422,15659098,15749712,15772280,16792691 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid) BIOGRID_4780|BIOGRID_16590|BIOGRID_2641|UniProt_11956|BIOGRID_2642|UniProt_12485|UniProt_12195|UniProt_11962|BIOGRID_5831|BIOGRID_2597|BIOGRID_16592 prey|prey|prey|prey|prey|prey|prey|bait|prey|prey|bait bait|bait|bait|bait|bait|bait|bait|prey|bait|bait|prey RBX1A CUL1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0006(anti bait coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid) 12215511,12381738,12839993,15659098,15749712 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_12205|UniProt_16665|UniProt_17797|UniProt_16625|UniProt_16663|UniProt_12835 prey|bait|bait|prey|bait|prey bait|prey|prey|bait|prey|bait RBX1A ADO1 MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 15447654 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_16414|BIOGRID_236 prey|prey bait|bait COI1 RBX1A MI:0018(two hybrid) 12172031 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (biogrid) BIOGRID_2105 bait prey

PPI - HINT Gene A Gene B PMID Method Quality CUL4 RBX1A 16844902,16792691,16844902,16844902,12381738 0004,0018,0018,0007,0018 LC RBX1A CUL1 15659098,12381738,12381738,15749712 0018,0096,0018,0018 LC RBX1A CUL3B 15659098,15618422,15618422,15749712 0018,0018,0096,0018 LC RBX1A COP10 16844902 0071 LC RBX1A CUL3A 15618422,15659098,15772280,15772280,15618422,15749712,16792691 0018,0018,0004,0401,0096,0018,0018 LC COI1 RBX1A 12172031 0004 LC DET1 RBX1A 16792691 0096 LC TIR1 RBX1A 12215511 0096 LC CUL4 RBX1A 16844902,16844902,16844902 0004,0018,0007 LC RBX1A CUL1 12839993,12381738,12381738,12215511,15860010,17158585 0006,0096,0018,0096,0004,0004 LC RBX1A ADO1 15447654,15447654 0004,0007 LC RBX1A CUL3B 15618422,15618422 0018,0096 LC RBX1A SKP1B 12381738,12381738 0004,0007 LC RBX1A RCE1 12682009 0096 LC RBX1A TIR 12215511 0096 LC RBX1A CUL3A 15618422,15772280,15772280,15618422 0018,0004,0401,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q940X7 Q570C0 RBX1A TIR1 0.21 12215511 Q9LJD7 Q940X7 COP10 RBX1A 0.21 16844902 Q9ZNU6 Q940X7 DET1 RBX1A 0.21 16792691 Q94BT6 Q940X7 ADO1 RBX1A 0.376 15447654 Q9FHW7 Q940X7 SKP1B RBX1A 0.376 12381738 Q940X7 Q8LGH4 RBX1A CUL4 0.932 16792691,16844902,12381738 Q9ZVH4 Q940X7 CUL3A RBX1A 0.972 15659098,16792691,15618422,15772280,15749712 Q94AH6 Q940X7 CUL1 RBX1A 0.984 15659098,12839993,15860010,12381738,15749712,12215511,17158585 Q940X7 P48732 RBX1A DET1 0.309 16792691 Q9C9L0 Q940X7 CUL3B RBX1A 0.876 15659098,15749712,15618422 Q9SSN3 Q940X7 TIR RBX1A 0.309 12215511 Q9SDY5 Q940X7 RCE1 RBX1A 0.623 12682009 Q940X7 O04197 RBX1A COI1 0.21 12172031