PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P35131 Q9SI09 two hybrid 16792696 direct interaction X 2 Q9MAB9 P35131 two hybrid 21345795 direct interaction X 2 Q9SH14 P35131 two hybrid 21345795 direct interaction X 2 Q9LSD8 P35131 two hybrid 21345795 direct interaction X 2 Q8GWJ6 P35131 two hybrid 21345795 direct interaction X 2 Q1EC66 P35131 affinity chromatography technology 23667124 physical association X 2 Q9SRS9 P35131 two hybrid 16640601 direct interaction X 2 P39940 P35131 pull down 10490634 direct interaction X 2 P39940 P35131 pull down 9858558 direct interaction X 2 P35131 Q6NQG7 pull down 23831064 direct interaction X 2 Q84ME1 P35131 two hybrid 21798944 direct interaction X 2 Q9SW27 P35131 two hybrid 21345795 direct interaction X 2 Q9SW27 P35131 pull down 21345795 direct interaction X 2 Q9SW27 P35131 affinity chromatography technology 21345795 physical association X 2 Q9SW27 P35131 protein complementation assay 21345795 direct interaction X 2 Q8LCS8 P35131 two hybrid 21345795 direct interaction X 2 F4K3Z6 P35131 pull down 23742014 direct interaction X 2 Q9SPL2 P35131 pull down 12028569 direct interaction X 2 P46934-4 P35131 pull down 10490634 direct interaction X 2 Q84ME1 P35131 two hybrid array 21798944 physical association X 2 Q9SPL2 P35131 pull down 12028569 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBC8 MUB5 MI:0018(two hybrid) 21345795 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_6588 prey bait UBC8 XERICO MI:0018(two hybrid) 16792696 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_3204 prey bait UBC8 CIP8 MI:0096(pull down)|MI:0096(pull down) 12028569 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_16034|BIOGRID_2095 bait|bait prey|prey UBC8 UBQ3 MI:0004(affinity chromatography technology) 23667124 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (biogrid) BIOGRID_18838 prey bait UBC8 MUB2 MI:0018(two hybrid) 21345795 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_6570 prey bait UBC8 MUB1 MI:0018(two hybrid) 21345795 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_6567 prey bait UBC8 ATL78 MI:0415(enzymatic study) 23831064 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_17387 prey bait UBC8 KEG MI:0415(enzymatic study) 23742014 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_17766 prey bait UBC8 MUB3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21345795 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_6574|BIOGRID_6599|BIOGRID_6597|BIOGRID_6598 prey|bait|bait|bait bait|prey|prey|prey UBC8 MUB6 MI:0018(two hybrid) 21345795 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_6592 prey bait UBC8 CHIP MI:0018(two hybrid) 16640601 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_3342 prey bait UBC8 MUB4 MI:0018(two hybrid) 21345795 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_6581 prey bait UBC8 LUL3 MI:0397(two hybrid array)|MI:0018(two hybrid) 21798944 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_3288|BIOGRID_11548 prey|prey bait|bait

PPI - HINT Gene A Gene B PMID Method Quality ARP2 UBC8 21345795 0018 LC UBC8 LUL3 21798944,21798944 0018,0397 HT UBC8 MUB6 21345795 0018 LC UBC8 MUB2 21345795 0018 LC UBC8 Q8RX26 27497447 0018 LC UBC8 MUB1 21345795 0018 LC UBC8 T8K14.20 27497447 0018 LC UBC8 MUB5 21345795 0018 LC UBC8 XERICO 16792696 0018 LC UBC8 CHIP 16640601 0018 LC UBC8 MUB3 21345795,21345795,PDB_4X57,21345795,21345795 0096,0004,0114,0090,0018 LC UBC8 ATL78 23831064 0096 LC UBC8 KEG 23742014 0096 LC UBC8 CIP8 12028569 0096 LC UBC8 MUB3 21345795,21345795,21345795,21345795 0096,0004,0090,0018 LC