PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O22467 Q8L6Y4 affinity chromatography technology 23778966 physical association X 2 O22467 Q8L6Y4 affinity chromatography technology 23778966 physical association X 2 O22467 P93831 affinity chromatography technology 23778966 physical association X 2 O22467 Q9LT47 affinity chromatography technology 23778966 physical association X 2 O22467 Q9ZSM8 affinity chromatography technology 23778966 physical association X 2 O22467 Q9SUM4-3 affinity chromatography technology 23778966 physical association X 2 O22467 Q058P7 affinity chromatography technology 23778966 physical association X 2 O22467 Q058P7 affinity chromatography technology 23778966 physical association X 2 O22467 O65312 biochemical 12970192 colocalization X 2 O22467 O65312 affinity chromatography technology 12970192 physical association X 2 O22467 Q9LT47 affinity chromatography technology 12970192 physical association X 2 O22467 Q9LT47 pull down 12970192 direct interaction X 2 O22467 B3H6I9 two hybrid 21240189 direct interaction X 2 O22467 B3H6I9 pull down 21240189 direct interaction X 2 O22467 B3H6I9 protein complementation assay 21240189 direct interaction X 2 O22467 Q8LGH4 affinity chromatography technology 21240189 physical association X 2 O22467 O22467 affinity chromatography technology 23778966 physical association X 2 O22467 Q9LHF5 affinity chromatography technology 23778966 physical association X 2 O22467 F4JMM5 affinity chromatography technology 23778966 physical association X 2 O22467 Q9LYD9 pull down 18281509 direct interaction X 2 O22467 Q9LKZ3 pull down 18700816 direct interaction X 2 O22467 tandem affinity purification 18854416 - C 7 O22467 Q9LKZ3 bimolecular fluorescence complementation 18700816 direct interaction X 2 O22467 Q9LKZ3 pull down 18700816 direct interaction X 2 O22467 Q9LHF5 tandem affinity purification 18854416 physical association X 2 O22467 anti tag coimmunoprecipitation 23778966 association C 32 O22467 Q9LT47 anti bait coimmunoprecipitation 12970192 physical association X 2 O22467 O65312 anti bait coimmunoprecipitation 12970192 physical association X 2 O22467 Q9LT47 pull down 12970192 physical association X 2 O22467 Q9LT47 two hybrid 18812497 physical association X 2 O22467 Q8LGH4 anti bait coimmunoprecipitation 21240189 physical association X 2 O22467 P93831 anti tag coimmunoprecipitation 23778966 physical association X 2 O22467 Q058P7 anti tag coimmunoprecipitation 23778966 physical association X 2 O22467 Q058P7 anti tag coimmunoprecipitation 23778966 physical association X 2 O22467 Q8L6Y4 anti tag coimmunoprecipitation 23778966 physical association X 2 O22467 anti tag coimmunoprecipitation 23778966 association C 6 O22467 molecular sieving 12970192 physical association C 3 O22467 protein cross-linking with a bifunctional reagent 23778966 association C 6 O22467 Q9M0V3 two hybrid 21240189 physical association X 2 O22467 Q9M0V3 pull down 21240189 direct interaction X 2 O22467 Q9M0V3 bimolecular fluorescence complementation 21240189 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B MSI1 EMF2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 23778966 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(intact)|(biogrid) UniProt_9048|UniProt_9056|UniProt_9047|BIOGRID_17677|UniProt_9045|BIOGRID_17680 bait|bait|prey|prey|prey|prey prey|prey|bait|bait|bait|bait MSI1 LHP1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 23778966 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(biogrid)|(intact)|(intact) UniProt_9048|UniProt_9056|BIOGRID_17689|BIOGRID_17688|UniProt_9050|UniProt_9051 bait|bait|prey|bait|prey|prey prey|prey|bait|prey|bait|bait MSI1 CLF MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 23778966 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_17681|UniProt_9046 prey|prey bait|bait MSI1 RBR1 MI:0096(pull down) 18700816 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_955 bait prey MSI1 DDB1A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21240189 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(biogrid)|(intact)|(biogrid)|(biogrid)|(intact) UniProt_9479|BIOGRID_6507|UniProt_9480|BIOGRID_6505|BIOGRID_6503|UniProt_9481 prey|prey|neutral component|prey|prey|prey null|bait|null|bait|bait|null MSI1 CUL4 MI:0018(two hybrid)|MI:0018(two hybrid) 21240189 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_6509|UniProt_9483 prey|prey bait|bait MSI1 FIE MI:0007(anti tag coimmunoprecipitation)|MI:0071(molecular sieving)|MI:0401(biochemical)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0071(molecular sieving)|MI:0401(biochemical)|MI:0071(molecular sieving)|MI:0007(anti tag coimmunoprecipitation) 12970192,18812497,23778966 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (intact)|(intact)|(biogrid)|(intact)|(biogrid)|(intact)|(biogrid)|(intact)|(intact) UniProt_9048|UniProt_16709|BIOGRID_2397|UniProt_11210|BIOGRID_17683|UniProt_16712|BIOGRID_2396|UniProt_16710|UniProt_9056 bait|neutral component|bait|prey|bait|bait|prey|prey|bait prey|neutral component|prey|bait|prey|prey|bait|bait|prey MSI1 EMF1 MI:0096(pull down) 18281509 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0407(direct interaction) (biogrid) BIOGRID_692 bait prey MSI1 MEA MI:0071(molecular sieving)|MI:0071(molecular sieving)|MI:0401(biochemical)|MI:0401(biochemical) 12970192 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(biogrid) UniProt_16709|UniProt_16711|BIOGRID_2394|BIOGRID_2395 neutral component|prey|prey|prey neutral component|bait|bait|bait MSI1 VIL2 MI:0004(affinity chromatography technology) 23778966 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association) (biogrid) BIOGRID_17686 bait prey MSI1 VRN2 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 23778966 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_9048|BIOGRID_17687 bait|bait prey|prey MSI1 EZA1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 23778966 taxid:3702(Arabidopsis thaliana) taxid:3702(Arabidopsis thaliana) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_17684|UniProt_9048|UniProt_9056 bait|bait|bait prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality MSI1 MEA 12970192,12970192,12970192 0006,0401,0004 LC MSI1 EMF2 23778966,23778966,23778966 0031,0007,0004 LC MSI1 LHP1 23778966,23778966,23778966 0031,0007,0004 LC MSI1 RBR1 18700816,18700816 0096,0809 LC MSI1 FIE 23778966,12970192,12970192,23778966,12970192,18812497,23778966,12970192 0007,0006,0071,0031,0096,0018,0004,0004 LC MSI1 DDB1A 21240189,21240189,21240189,21240189 0090,0018,0096,0809 LC MSI1 VIL2 23778966,23778966,23778966 0031,0007,0004 LC MSI1 EZA1 23778966,23778966,23778966 0031,0007,0004 LC A8MRU4 MSI1 23778966 0007 LC F4I764 MSI1 23778966 0007 LC IMPA2 MSI1 23778966 0007 LC SNL4 MSI1 23778966 0007 LC HDA19 MSI1 23778966 0007 LC MSI1 MSI1 23778966 0004 LC MSI1 RPL6 23778966 0007 LC MSI1 SNL3 23778966 0007 LC MSI1 O50068 23778966 0007 LC MSI1 MEA 12970192,12970192,12970192 0006,0401,0004 LC MSI1 CCT1 23778966 0007 LC MSI1 RPS2C 23778966 0007 LC MSI1 RPL26A 23778966 0007 LC MSI1 CLF 23778966,23778966 0007,0004 LC MSI1 ALY3 23778966 0007 LC MSI1 ALY2 23778966 0007 LC MSI1 Q8L603 23778966 0007 LC MSI1 EMF2 23778966,23778966,23778966 0031,0007,0004 LC MSI1 GIF1 24888433 0004 LC MSI1 CUL4 21240189,21240189 0006,0004 LC MSI1 Q8RWV9 23778966 0007 LC MSI1 VRN2 23778966,23778966 0007,0004 LC MSI1 LHP1 23778966,23778966,23778966 0031,0007,0004 LC MSI1 Q94EI6 23778966 0007 LC MSI1 CCT8 23778966 0007 LC MSI1 IMPA1 23778966 0007 LC MSI1 E2FB 23778966 0007 LC MSI1 SNL2 23778966 0007 LC MSI1 VIL1 23778966,18854416,23778966 0007,0676,0004 LC MSI1 RBR1 18700816,18700816 0096,0809 LC MSI1 FIE 23778966,12970192,12970192,23778966,12970192,23778966,12970192 0007,0006,0071,0031,0096,0004,0004 LC MSI1 EMF1 18281509 0096 LC MSI1 RPS26C 23778966 0007 LC MSI1 DDB1A 21240189,21240189,21240189,21240189 0090,0018,0096,0809 LC MSI1 VIL2 23778966,23778966,23778966 0031,0007,0004 LC MSI1 TCX5 23778966 0007 LC MSI1 RPL14B 23778966 0007 LC MSI1 SNL6 23778966 0007 LC MSI1 EZA1 23778966,23778966,23778966 0031,0007,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8L8A5 O22467 GIF1 MSI1 0.21 24888433 Q9LKZ3 O22467 RBR1 MSI1 0.671 18700816 O23049 O22467 RPL6 MSI1 0.126 23778966 O22467 O22467 MSI1 MSI1 0.155 23778966 O22467 O22446 MSI1 HDA19 0.126 23778966 O22467 F4I764 MSI1 F4I764 0.126 23778966 O22467 A8MRU4 MSI1 A8MRU4 0.126 23778966 O22467 O04539 MSI1 SNL4 0.126 23778966 O22467 F4JL11 MSI1 IMPA2 {ECO:0000303|PUBMED:18836040} 0.126 23778966 Q6A333 O22467 ALY2 MSI1 0.126 23778966 O48686 O22467 SNL3 MSI1 0.126 23778966 P28769 O22467 CCT1 MSI1 0.126 23778966 O50068 O22467 O50068 MSI1 0.126 23778966 Q6A332 O22467 ALY3 MSI1 0.126 23778966 P51414 O22467 RPL26A MSI1 0.126 23778966 P49688 O22467 RPS2C MSI1 0.126 23778966 Q8L603 O22467 Q8L603 MSI1 0.126 23778966 Q9LFQ3 O22467 SNL2 MSI1 0.126 23778966 Q8RWV9 O22467 Q8RWV9 MSI1 0.126 23778966 Q8LGH4 O22467 CUL4 MSI1 0.21 21240189 Q9FV71 O22467 E2FB MSI1 0.126 23778966 Q94K05 O22467 T11I18.7 MSI1 0.126 23778966 Q94EI6 O22467 Q94EI6 MSI1 0.126 23778966 Q96321 O22467 KAP1 MSI1 0.126 23778966 Q9LYK9 O22467 RPS26C MSI1 0.126 23778966 Q9LYD9 O22467 EMF1 MSI1 0.309 18281509 Q9SZD1 O22467 TCX5 MSI1 0.126 23778966 Q9XIK6 O22467 SNL6 MSI1 0.126 23778966 Q9T043 O22467 RPL14B MSI1 0.126 23778966 Q946J8 O22467 LHP1 MSI1 0.49 23778966 P93831 O22467 CLF MSI1 0.236 23778966 Q8L6Y4 O22467 EMF2 MSI1 0.49 23778966 Q8W5B1 O22467 VRN2 MSI1 0.236 23778966 Q9LHF5 O22467 VIL1 MSI1 0.396 18854416,23778966 Q9ZSM8 O22467 EZA1 MSI1 0.332 23778966 Q9SUM4 O22467 VIL2 MSI1 0.332 23778966 O65312 O22467 MEA MSI1 0.454 12970192 Q9LT47 O22467 FIE MSI1 0.876 12970192,23778966,18812497 Q9M0V3 O22467 DDB1A MSI1 0.82 21240189