PTM - CPLM Gene Name UniProt ID Type Position Code SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 205 K SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 275 K SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 329 K SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 342 K SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 350 K SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 66 K SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 119 K SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 125 K SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 Ubiquitination 281 K

PTM - dbPAF Gene Name UniProt ID Position Type Species SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 101 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 11 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 122 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 147 T Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 151 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 152 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 154 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 197 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 203 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 237 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 253 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 261 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 283 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 286 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 290 T Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 325 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 328 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 331 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 334 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 357 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 5 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 6 S Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 7 T Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 75 Y Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 85 T Homo sapiens(Human) SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R O75563 9 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O75563 S5-p Phosphorylation ___MPNPsstSsPyP O75563 S6-p Phosphorylation __MPNPsstSsPyPL O75563 T7-p Phosphorylation _MPNPsstSsPyPLP O75563 S9-p Phosphorylation PNPsstSsPyPLPEE O75563 Y11-p Phosphorylation PsstSsPyPLPEEIR O75563 S47-p Phosphorylation KAKEKREsLIKKIKD O75563 Y75-p Phosphorylation DAEDGEEyDDPFAGP O75563 T85-p Phosphorylation PFAGPPDtISLASER O75563 Y122-p Phosphorylation PFVLkAGyLEkRRKD O75563 T147-p Phosphorylation RWCALSKtVFYyyGs O75563 Y151-p Phosphorylation LSKtVFYyyGsDKDK O75563 Y152-p Phosphorylation SKtVFYyyGsDKDKQ O75563 S154-p Phosphorylation tVFYyyGsDKDKQQK O75563 Y197-p Phosphorylation SAPDKRIyQFTAAsP O75563 S203-p Phosphorylation IyQFTAAsPkDAEEW O75563 Y237-p Phosphorylation YDERGELyDDVDHPL O75563 S253-p Phosphorylation ISNPLTSsQPIDDEI O75563 Y261-p Phosphorylation QPIDDEIyEELPEEE O75563 S283-p Phosphorylation VEEQRkMsQDsVHHt O75563 S286-p Phosphorylation QRkMsQDsVHHtSGD O75563 T290-p Phosphorylation sQDsVHHtSGDKSTD O75563 Y325-p Phosphorylation FKRGDVIyILskEyN O75563 S328-p Phosphorylation GDVIyILskEyNRyG O75563 Y331-p Phosphorylation IyILskEyNRyGWWV O75563 Y334-p Phosphorylation LskEyNRyGWWVGEM O75563 Y357-p Phosphorylation kAYIMEMyDI_____ O75563 K66-ub Ubiquitination YLQEFQDkGDAEDGE O75563 K119-ub Ubiquitination QDLPFVLkAGyLEkR O75563 K125-ub Ubiquitination LkAGyLEkRRKDHSF O75563 K205-ub Ubiquitination QFTAAsPkDAEEWVQ O75563 K281-ub Ubiquitination VKVEEQRkMsQDsVH O75563 K329-ub Ubiquitination DVIyILskEyNRyGW O75563 K350-ub Ubiquitination GAIGLVPkAYIMEMy

PTM - dbPTM UniProt ID Position Code Type Resources References O75563 151 Y Phosphorylation Swiss-Prot 1010711 18083107 O75563 197 Y Phosphorylation Swiss-Prot 1010711 18083107 O75563 325 Y Phosphorylation Swiss-Prot 1010711 17081983 O75563 286 S Phosphorylation PhosphoELM.10011 18669648 O75563 290 T Phosphorylation PhosphoELM.10011 18669648 O75563 151 Y Phosphorylation PhosphoELM.10011 18083107 O75563 197 Y Phosphorylation PhosphoELM.10011 18083107 O75563 119 K Ubiquitylation Phosphositeplus.1010730 21906983 O75563 125 K Ubiquitylation Phosphositeplus.1010730 21906983 O75563 205 K Ubiquitylation Phosphositeplus.1010730 21906983 O75563 281 K Ubiquitylation Phosphositeplus.1010730 21906983 O75563 329 K Ubiquitylation Phosphositeplus.1010730 21906983 O75563 350 K Ubiquitylation Phosphositeplus.1010730 21906983 O75563 66 K Ubiquitylation Phosphositeplus.1010730 21906983 O75563 286 S Phosphorylation Phosphositeplus.1010730 18669648 O75563 151 Y Phosphorylation Phosphositeplus.1010730 18083107 O75563 197 Y Phosphorylation Phosphositeplus.1010730 18083107;21253578 O75563 261 Y Phosphorylation Phosphositeplus.1010730 21253578 O75563 75 Y Phosphorylation Phosphositeplus.1010730 21719704 O75563 286 S Phosphorylation HPRD 9.0 18669648 O75563 290 T Phosphorylation HPRD 9.0 18669648 O75563 197 Y Phosphorylation HPRD 9.0 15592455 O75563 325 Y Phosphorylation HPRD 9.0 17081983 O75563 325 Y Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References SKAP2 197 Y Phosphorylation 15592455 SKAP2 286 S Phosphorylation 18669648 SKAP2 290 T Phosphorylation 18669648 SKAP2 325 Y Phosphorylation 17081983

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O75563 151 Y 18083107 HTP Phosphorylation O75563 286 S 18669648 HTP Phosphorylation O75563 197 Y 18083107 HTP Phosphorylation O75563 290 T 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O75563 5 Phosphoserine 23186163 O75563 6 Phosphoserine 23186163;24275569 O75563 75 Phosphotyrosine 21719704 O75563 197 Phosphotyrosine 24275569

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 8935 114448 - K Ubiquitination 21906983

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID SKAP2 Homo sapiens (Human) 119; 205; 66; 350; 125; 281; 329 "119,DLPFVLKAGYLEK; 205,FTAASPKDAEEWV; 66,LQEFQDKGDAEDG; 350,AIGLVPKAYIMEM; 125,KAGYLEKRRKDHS; 281,KVEEQRKMSQDSV; 329,VIYILSKEYNRYG" 119:21906983; 205:21906983; 66:21906983; 350:21906983; 125:21906983; 281:21906983; 329:21906983