PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PSMD2 NUB1 22434192 biogrid exp GP GP G G GP G G GP GP G GP GP GP G G GP G GP GP G GP GP G GP GP GP GP GP G MAP3K6 NUB1 20936779 i2d exp GP GP P G GP GP GP P GP GP G GP GP GP P GP G GP GP GP GP P G RNF168 NUB1 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SF3B4 NUB1 25416956 biogrid,intact exp G GP G G GP G G GP GP G GP G GP G G G G G GP G GP G G G G G GP GP G PSMB4 NUB1 16707496 biogrid exp G GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G G GP GP GP GP G ECT2 NUB1 22990118 biogrid exp G G G G G G G G G G GSK3B NUB1 22965877 biogrid exp G G G G G G G G GP G G G G G G G G G G G GP G G G G G G G G FANCA NUB1 14499622 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G MAPT NUB1 22965877 biogrid exp G GP G G G G G GP GP G GP GP G GP G G G G GP G G GP G GP G G GP GP G FAT1 NUB1 22347407 biogrid exp GP GP G G G G G G GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G COPB1 NUB1 21988832 biogrid,intact exp GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBE2K NUB1 16877356 biogrid exp GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G HTT NUB1 17500595 intact exp GP GP G G GP G G G GP G P GP P GP G GP G GP P G GP GP G G GP GP GP GP UBC NUB1 23649778 biogrid exp GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G HSPA4 NUB1 18408180 biogrid exp GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UFD1L NUB1 24019527 biogrid exp G GP G G G G G GP GP G GP G GP GP G GP G G GP G GP GP G GP GP G G GP G VCP NUB1 24100225,24019527 biogrid exp GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G TP53 NUB1 20101219 biogrid exp G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G SHFM1 NUB1 24811749 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NUB1 SNCAIP 16877356,17549501, 21836163 biogrid exp, pred GP GP G P G P GP P P P GP G P G GP P P GP P P GP GP GP G AIPL1 NUB1 15081406,12374762,15180275,22347407, 21836163 hprd,biogrid,i2d,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G PSMD4 NUB1 16171779,22434192,11585840, 21836163 hprd,biogrid exp, pred GP GP G G GP G G GP GP G GP GP GP GP G GP G G GP G GP GP G GP GP G GP GP G NEDD8 NUB1 16877356,11585840,17549501,16503656,20101219,11259415,12816948, 21836163 hprd,biogrid,mint,intact exp, pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBD NUB1 22434192,16707496,14757770, 21836163 hprd,biogrid exp, pred P P P P P P P P P P P P P P P P P P P RDH8 NUB1 21836163 pred G G G G G G G G G G G G G G G G RRH NUB1 21836163 pred GP GP G G G G G G P GP GP P GP GP G G GP G G GP G G P GP P GP UBQLNL NUB1 23023127 pred P P P P P P P P G P P P GP USP14 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G NAE1 NUB1 25402006 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G CPT1C NUB1 21836163 pred P G G G P G P P G P G P P P GP LRRC32 NUB1 21836163 pred G GP G G G GP G GP G G G G GP G G GP G G G G G GP G GP GP G ASMT NUB1 21836163 pred TMUB2 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UCHL3 NUB1 25402006 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G G GP G GP GP G GP GP GP GP GP G CUL5 NUB1 25402006 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G CASP8 NUB1 23023127 pred GP GP G GP GP GP GP GP GP GP G GP GP P G GP GP G P GP GP GP GP G IQUB NUB1 23023127 pred P P P P P GP P P P P P P P P P P P P GP KIF5A NUB1 21836163 pred GP GP G G GP G G GP GP G GP GP P GP G GP G G GP G GP GP G GP GP P GP GP G CIDEA NUB1 23023127 pred G G G G G G G G ACAD9 NUB1 21836163 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G G GP G GP GP G G GP GP GP GP G RABIF NUB1 16082366 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G RPGRIP1 NUB1 21836163 pred GP GP G G GP G G GP GP G GP G GP GP G P G GP GP G GP GP G GP P GP GP G GUCA1A NUB1 21836163 pred G G G G G G G G G G G G G G G G G G G KCNV2 NUB1 21836163 pred P P P P P P P P P P GP PLEKHB1 NUB1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G BAG6 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBXN1 NUB1 23023127 pred GP GP G G G G G G GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UHRF2 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G GUCA2A NUB1 21836163 pred P P P P DDI1 NUB1 23023127 pred P P G GP GP P G P P GP CUL4B NUB1 25402006 pred GP GP G G GP G G GP GP G GP GP G GP G GP G G GP G GP GP G GP GP GP GP GP G SENP8 NUB1 25402006 pred P P G P G G GP P G GP P P P P GP P G P GP GP GP P P GP HERPUD2 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G RAD23A NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G DCDC2 NUB1 23023127 pred P P GP GP GP G P G P TMUB1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP G GP GP G UBXN4 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G AMFR NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G SQSTM1 NUB1 23023127 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G FAF1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP G GP GP G GP G GP GP G GP GP G GP GP GP GP GP G EPHA3 NUB1 23023127 pred GP P P G GP GP P GP P GP G GP P GP GP P GP P GP P RBP3 NUB1 21836163 pred G G NCF2 NUB1 23023127 pred G G GP G G G GP GP G G G G G G G G GP G G BIRC2 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G G GP G GP G G GP GP GP GP GP G NSFL1C NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G G GP GP GP GP G USP13 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP G GP GP G EIF2AK1 NUB1 21836163 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G TDRD3 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G P GP G GP GP GP GP GP NOD2 NUB1 23023127 pred P G GP P P GP P P P P P P P GP P NUB1 TNFRSF18 21836163 pred G G G G GP G G G GP G GP G GP GP G G G G GP G GP G G G G GP GP GP G SOS2 NUB1 21836163 pred GP GP G G GP G G GP GP G GP G GP GP G GP G GP GP G GP GP G GP GP GP GP GP G LATS1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP G GP GP G IRAK2 NUB1 23023127 pred GP GP G G GP G G P P G GP GP GP GP GP G G G G G GP GP G GP P PARK2 NUB1 23023127 pred P GP G P G G GP GP G GP P P G P G GP P G P G GP GP P GP G TOLLIP NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP G GP GP G CUEDC1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP P G GP GP G GP GP GP GP P G RCVRN NUB1 21836163 pred G G RBBP6 NUB1 23023127 pred GP G G G G G G GP GP G GP GP GP G G GP G G G G GP G G G GP GP GP GP G UBA3 NUB1 25402006 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G RPE65 NUB1 21836163 pred MIDN NUB1 23023127 pred GP GP G G GP G G GP GP G GP G G G G GP G G G G GP GP G GP GP G GP GP G SELE NUB1 23023127 pred G P G G P G G G G G G G FGFRL1 NUB1 21836163 pred G GP G P G GP P G GP GP P GP G GP G GP P G GP P G GP GP P GP GP G CBL NUB1 23023127 pred G GP G G GP G G G GP G GP G GP GP G G G GP G G G G G G G GP G GP G LATS2 NUB1 23023127 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP G GP GP G GP GP G IQCB1 NUB1 21836163 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G G GP G GP GP G SARM1 NUB1 23023127 pred G G G G G G G GP G G GP G GP G G G G GP GP G G G G P G G G P G RAD23B NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBXN2B NUB1 23023127 pred G GP G G G G G G GP G GP G GP G G GP G GP G G G GP G G GP G GP GP G ADH7 NUB1 21836163 pred G G G GP P P P P G G G G G G P P P G UBQLN3 NUB1 23023127 pred G G G G G G GP G UBXN11 NUB1 23023127 pred G GP G G G G G GP P G GP GP GP G G GP G GP GP G GP GP G GP GP G GP GP G RIPK1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G SUMO2 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBQLN1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBE2M NUB1 25402006 pred GP GP G G GP G G GP GP G GP G GP GP G GP G GP GP G GP G G GP GP GP GP GP G SLC24A2 NUB1 21836163 pred P GP G G GP G G GP GP G GP GP P G P G GP GP G GP P G GP P P P GP G SUMO1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP G GP GP G GP G GP GP G GP GP G GP GP GP GP GP G CD86 NUB1 23023127 pred GP G G G GP G G G P G GP GP GP G GP G G P G GP P G G P GP GP P RIPK2 NUB1 23023127 pred GP GP G G GP G G GP GP G GP G GP GP G GP G GP GP G GP GP G GP GP G G GP G USP5 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBR5 NUB1 23023127 pred GP G G G G G G G GP G GP GP GP GP G G G G G G GP G G G G G GP GP G HERPUD1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G BCL2 NUB1 23023127 pred G G G G GP G G G GP G GP G G GP G G G GP G G GP GP G G G GP G G G RTN1 NUB1 21836163 pred GP G G G G G G G G G G G GP G G G G G IFT88 NUB1 21836163 pred GP GP G G GP G G GP GP G GP GP GP G G GP G GP GP G GP G G GP GP G G GP G KIF5C NUB1 21836163 pred GP GP G G GP G G GP GP G GP G GP GP G GP G G GP G GP GP G P GP GP GP GP G UBL4B NUB1 23023127 pred P P P P P P P P P P P P P P P P P ATP6V0C NUB1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO3 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G AXIN1 NUB1 23023127 pred GP GP G GP G G P GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G KIF3A NUB1 21836163 pred G GP G G GP G G G GP G G G G G G G G G GP G G G G G G G GP GP G CBLB NUB1 23023127 pred GP GP G G G G G G GP G GP GP GP GP G GP G GP GP G GP GP G G GP GP GP GP G UBC NUB1 23023127 pred HUWE1 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G NUB1 AUP1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G GPR75 NUB1 21836163 pred G G G G TNFSF18 NUB1 21836163 pred GP GP G G GP G P GP P GP GP GP P G GP GP G GP P G P P P P G CUL2 NUB1 25402006 pred GP GP G G G G G G GP G GP GP GP GP G G G GP GP G GP GP G G G G GP GP G VSX2 NUB1 21836163 pred P P P P P P P P P P P PRKCI NUB1 23023127 pred GP GP G G G G G G GP G GP G GP G G GP G G GP G GP GP G G GP G GP GP G RDH5 NUB1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SAG NUB1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G AANAT NUB1 21836163 pred P P P P P P P P P P P P P MYLIP NUB1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ROM1 NUB1 21836163 pred G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9Y5A7 Q15843 two hybrid 12816948 physical association X 2 Q9Y5A7 Q15843 two hybrid 12816948 physical association X 2 Q9Y5A7 Q15843 pull down 12816948 physical association X 2 Q9Y5A7 anti tag coimmunoprecipitation 24811749 association C 66 P42858 Q9Y5A7 two hybrid 17500595 physical association X 2 Q9Y5A7 F1T0B6 two hybrid 12374762 physical association X 2 Q9Y5A7 F1T0B6 anti bait coimmunoprecipitation 12374762 physical association X 2 Q15427 Q9Y5A7 two hybrid prey pooling approach 25416956 physical association X 2 Q15427 Q9Y5A7 two hybrid array 25416956 physical association X 2 Q15427 Q9Y5A7 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Gnl3l NUB1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23649778 taxid:10090(Mus musculus) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_281913|BIOGRID_330352 prey|prey bait|bait NUB1 SNCAIP MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16877356,17549501 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_215952|BIOGRID_207676|BIOGRID_207672 bait|bait|bait prey|prey|prey PSMD2 NUB1 MI:0018(two hybrid) 22434192 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_184596 prey bait UBE2K NUB1 MI:0018(two hybrid) 16877356 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_207674 prey bait VCP NUB1 MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down) 24019527,24100225 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_307919|BIOGRID_289356|BIOGRID_289355 prey|prey|prey bait|bait|bait UFD1L NUB1 MI:0096(pull down) 24019527 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_289360 bait prey MAPT NUB1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22965877 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_217528|BIOGRID_217529 bait|prey prey|bait FAT1 NUB1 MI:0004(affinity chromatography technology) 22347407 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_194648 bait prey GSK3B NUB1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22965877 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_217530|BIOGRID_217531 bait|prey prey|bait COPB1 NUB1 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_119567|BIOGRID_286168 unspecified role|bait unspecified role|prey p53 NUB1 MI:0096(pull down)|MI:0096(pull down) 20101219 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_144800|BIOGRID_144799 prey|bait bait|prey FANCA NUB1 MI:0018(two hybrid) 14499622 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_85632 bait prey ECT2 NUB1 MI:0004(affinity chromatography technology) 22990118 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_245933 bait prey AIPL1 NUB1 MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo) 12374762,15081406,22347407 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_194649|UniProt_69749|BIOGRID_116951|BIOGRID_210248|UniProt_69751|BIOGRID_210246|BIOGRID_116950|BIOGRID_210250|HPRD_13024 bait|prey|bait|bait|bait|bait|bait|prey|- prey|bait|prey|prey|prey|prey|prey|bait|- HSPA4 NUB1 MI:0018(two hybrid) 18408180 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_216759 bait prey PSMB4 NUB1 MI:0096(pull down) 16707496 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_196837 bait prey HTT NUB1 MI:0018(two hybrid) 17500595 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_90855 bait prey NEDD8 NUB1 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0096(pull down)|MI:0096(pull down) 11259415,11585840,12816948,14757770,16503656,16877356,17549501,20101219,24019527 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(biogrid)|MI:0471(mint)|(intact)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid) BIOGRID_215951|BIOGRID_87044|BIOGRID_144795|UniProt_73129|BIOGRID_144794|UniProt_73127|BIOGRID_207673|MINT_55604|UniProt_73128|MINT_55606|BIOGRID_195200|MINT_55605|BIOGRID_194592|MINT_58428|MINT_58426|MINT_58427|BIOGRID_195199|HPRD_12109|BIOGRID_103635|BIOGRID_289354 prey|prey|bait|bait|prey|unspecified role|prey|unspecified role|unspecified role|bait|bait|unspecified role|bait|bait|unspecified role|unspecified role|bait|-|bait|bait bait|bait|prey|null|bait|null|bait|null|null|null|prey|null|prey|null|null|null|prey|-|prey|prey UBC NUB1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16196087,18781797,21890473,21906983,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_177799|BIOGRID_268808|BIOGRID_162356|BIOGRID_142957|BIOGRID_175832 bait|bait|bait|bait|bait prey|prey|prey|prey|prey UBD NUB1 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 14757770,16707496,22434192 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) HPRD_14740|BIOGRID_87043|BIOGRID_196830|BIOGRID_87045|BIOGRID_196831|BIOGRID_184610|BIOGRID_184591 -|prey|bait|prey|prey|prey|bait -|bait|prey|bait|bait|bait|prey PSMD4 NUB1 MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid) 11585840,16171779,22434192 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid) BIOGRID_188231|BIOGRID_103636|BIOGRID_188230|BIOGRID_184590|HPRD_9531|BIOGRID_184612|BIOGRID_184593 prey|prey|prey|bait|-|bait|prey bait|bait|bait|prey|-|prey|bait

PPI - HINT Gene A Gene B PMID Method Quality UBD NUB1 22434192,14757770,14757770,16707496,22434192,16707496 0018,0096,0004,0004,0096,0096 LC PSMD4 NUB1 22434192,22434192,16171779,16171779,11585840 0018,0096,0004,0018,0096 LC NEDD8 NUB1 20101219,12816948,14757770,20101219,12816948,11585840,16503656 0096,0018,0004,0018,0096,0096,0004 LC RNF168 NUB1 26496610,26496610 0007,0004 HT AIPL1 NUB1 15081406,12374762,12374762,22347407,12374762,12374762,15081406,12374762,15180275 0018,0006,0019,0004,0018,0004,0004,0045,0004 LC NUB1 HEL-S-70 24019527,24100225,24019527 0096,0096,0004 LC RNF168 NUB1 26496610,26496610 0007,0004 HT UBD NUB1 22434192,14757770,14757770,16707496,22434192,16707496 0018,0096,0004,0004,0096,0096 LC PSMD4 NUB1 22434192,22434192,16171779,16171779,11585840 0018,0096,0004,0018,0096 LC NEDD8 NUB1 20101219,12816948,14757770,20101219,12816948,11585840,16503656 0096,0018,0004,0018,0096,0096,0004 LC AIPL1 NUB1 15081406,12374762,12374762,22347407,12374762,12374762,15081406,12374762,15180275 0018,0006,0019,0004,0018,0004,0004,0045,0004 LC NUB1 HEL-S-70 24019527,24100225,24019527 0096,0096,0004 LC UBD NUB1 22434192,22434192 0018,0096 LC FANCA NUB1 14499622 0018 LC HSPA4 NUB1 18408180 0401 LC HTT NUB1 17500595 0018 LC COPB1 NUB1 21988832 0018 HT PSMD4 NUB1 22434192,22434192,16171779,16171779 0018,0096,0004,0018 LC UBE2K NUB1 16877356 0018 LC SF3B4 NUB1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT NEDD8 NUB1 16877356,11259415,20101219,12816948,17549501,20101219,12816948 0018,0018,0096,0018,0018,0018,0096 LC AIPL1 NUB1 15081406,12374762,12374762,12374762,12374762,15081406,12374762 0018,0006,0019,0018,0004,0004,0045 LC NUB1 SNCAIP 16877356,17549501,16877356 0018,0018,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y5A7 O15360 NUB1 FANCA 0.183 14499622 Q9Y5A7 Q9H8V3 NUB1 ECT2 0.126 22990118 Q9Y5A7 Q9NZN9 NUB1 AIPL1 0.872 15180275,12374762,22347407,15081406 Q9Y5A7 P10636 NUB1 MAPT 0.376 22965877 Q9Y5A7 P04637 NUB1 TP53 0.376 20101219 Q9Y5A7 Q13200 NUB1 PSMD2 0.309 22434192 Q9Y5A7 P38886 NUB1 RPN10 0.309 22434192 Q9Y5A7 P61086 NUB1 UBE2K 0.309 16877356 Q9Y5A7 P0CG48 NUB1 UBC 0.286 23649778 Q9Y5A7 Q8IYW5 NUB1 RNF168 0.236 26496610 Q9Y5A7 O15205 NUB1 UBD 0.858 22434192,16707496,14757770 Q9Y5A7 P55036 NUB1 PSMD4 0.876 11585840,16171779,22434192 Q9Y5A7 P60896 NUB1 SHFM1 0.236 24811749 Q9Y5A7 P53618 NUB1 COPB1 0.332 21988832 Q9Y5A7 P54274 NUB1 TERF1 0.837 27214791 Q9Y5A7 P55072 NUB1 VCP 0.623 24100225,24019527 Q9Y6H5 Q9Y5A7 SNCAIP NUB1 0.623 17549501,16877356 Q9Y5A7 Q15427 NUB1 SF3B4 0.454 25416956 Q9Y5A7 Q15843 NUB1 NEDD8 0.953 17549501,12816948,16503656,11585840,16877356,20101219 Q9Y5A7 Q92890 NUB1 UFD1L 0.309 24019527 Q9Y5A7 P28070 NUB1 PSMB4 0.21 16707496 Q9Y5A7 P34932 NUB1 HSPA4 0.126 18408180 Q9Y5A7 Q14517 NUB1 FAT1 0.21 22347407 Q9Y5A7 P49841 NUB1 GSK3B 0.376 22965877 Q9Y5A7 P42858 NUB1 HTT 0.183 17500595

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 NOP56 NUB1 MI:0362 inference MI:0461 interaction database DDX3X NUB1 MI:0362 inference MI:0461 interaction database UBD NUB1 MI:0045 experimental interaction detection MI:0461 interaction database FANCA NUB1 MI:0045 experimental interaction detection MI:0461 interaction database NARS NUB1 MI:0362 inference MI:0461 interaction database SYNCRIP NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BK NUB1 MI:0362 inference MI:0461 interaction database SRP72 NUB1 MI:0362 inference MI:0461 interaction database LUC7L3 NUB1 MI:0362 inference MI:0461 interaction database SGPL1 NUB1 MI:0362 inference MI:0461 interaction database ZBTB11 NUB1 MI:0362 inference MI:0461 interaction database TUBB4A NUB1 MI:0362 inference MI:0461 interaction database TP53 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2AB NUB1 MI:0362 inference MI:0461 interaction database SLC25A5 NUB1 MI:0362 inference MI:0461 interaction database RPLP1 NUB1 MI:0362 inference MI:0461 interaction database RPLP2 NUB1 MI:0362 inference MI:0461 interaction database RPLP0 NUB1 MI:0362 inference MI:0461 interaction database SSB NUB1 MI:0362 inference MI:0461 interaction database NPM1 NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BJ NUB1 MI:0362 inference MI:0461 interaction database TUBB NUB1 MI:0362 inference MI:0461 interaction database EPRS NUB1 MI:0362 inference MI:0461 interaction database VIM NUB1 MI:0362 inference MI:0461 interaction database RPS17 NUB1 MI:0362 inference MI:0461 interaction database SRP19 NUB1 MI:0362 inference MI:0461 interaction database PARP1 NUB1 MI:0362 inference MI:0461 interaction database H2AFZ NUB1 MI:0362 inference MI:0461 interaction database HIST1H2AG NUB1 MI:0362 inference MI:0461 interaction database UBC NUB1 MI:0045 experimental interaction detection MI:0461 interaction database MAPT NUB1 MI:0045 experimental interaction detection MI:0461 interaction database HSPA5 NUB1 MI:0362 inference MI:0461 interaction database HSPA8 NUB1 MI:0362 inference MI:0461 interaction database PABPC1 NUB1 MI:0362 inference MI:0461 interaction database SLC25A4 NUB1 MI:0362 inference MI:0461 interaction database PKM NUB1 MI:0362 inference MI:0461 interaction database RAC2 NUB1 MI:0362 inference MI:0461 interaction database RPS2 NUB1 MI:0362 inference MI:0461 interaction database H2AFX NUB1 MI:0362 inference MI:0461 interaction database YBX3 NUB1 MI:0362 inference MI:0461 interaction database DDX5 NUB1 MI:0362 inference MI:0461 interaction database RPL7 NUB1 MI:0362 inference MI:0461 interaction database NCL NUB1 MI:0362 inference MI:0461 interaction database EIF2S2 NUB1 MI:0362 inference MI:0461 interaction database HIST1H2AD NUB1 MI:0362 inference MI:0461 interaction database RPS3 NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BO NUB1 MI:0362 inference MI:0461 interaction database ATP5A1 NUB1 MI:0362 inference MI:0461 interaction database DNMT1 NUB1 MI:0362 inference MI:0461 interaction database EEF1G NUB1 MI:0362 inference MI:0461 interaction database RPL10 NUB1 MI:0362 inference MI:0461 interaction database PSMB4 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database EEF1D NUB1 MI:0362 inference MI:0461 interaction database OAS2 NUB1 MI:0362 inference MI:0461 interaction database RPL12 NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BB NUB1 MI:0362 inference MI:0461 interaction database RPL22 NUB1 MI:0362 inference MI:0461 interaction database RPL4 NUB1 MI:0362 inference MI:0461 interaction database RPL3 NUB1 MI:0362 inference MI:0461 interaction database RPL35 NUB1 MI:0362 inference MI:0461 interaction database HTT NUB1 MI:0045 experimental interaction detection MI:0461 interaction database RPL27A NUB1 MI:0362 inference MI:0461 interaction database RPL5 NUB1 MI:0362 inference MI:0461 interaction database RPL21 NUB1 MI:0362 inference MI:0461 interaction database RPS9 NUB1 MI:0362 inference MI:0461 interaction database RPS5 NUB1 MI:0362 inference MI:0461 interaction database RPL34 NUB1 MI:0362 inference MI:0461 interaction database GSK3B NUB1 MI:0045 experimental interaction detection MI:0461 interaction database RPL14 NUB1 MI:0362 inference MI:0461 interaction database DAP3 NUB1 MI:0362 inference MI:0461 interaction database HNRNPM NUB1 MI:0362 inference MI:0461 interaction database HNRNPF NUB1 MI:0362 inference MI:0461 interaction database COPB1 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database COPA NUB1 MI:0362 inference MI:0461 interaction database PSMD4 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database VCP NUB1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BD NUB1 MI:0362 inference MI:0461 interaction database SHFM1 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2K NUB1 MI:0045 experimental interaction detection MI:0461 interaction database ABCE1 NUB1 MI:0362 inference MI:0461 interaction database RPL27 NUB1 MI:0362 inference MI:0461 interaction database RPL37A NUB1 MI:0362 inference MI:0461 interaction database RPS14 NUB1 MI:0362 inference MI:0461 interaction database RPS23 NUB1 MI:0362 inference MI:0461 interaction database RPS11 NUB1 MI:0362 inference MI:0461 interaction database RPL7A NUB1 MI:0362 inference MI:0461 interaction database RPS6 NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BC NUB1 MI:0362 inference MI:0461 interaction database RPL23 NUB1 MI:0362 inference MI:0461 interaction database RPS24 NUB1 MI:0362 inference MI:0461 interaction database RPS25 NUB1 MI:0362 inference MI:0461 interaction database RPS26 NUB1 MI:0362 inference MI:0461 interaction database RPL10A NUB1 MI:0362 inference MI:0461 interaction database RPL32 NUB1 MI:0362 inference MI:0461 interaction database RPL11 NUB1 MI:0362 inference MI:0461 interaction database RPL8 NUB1 MI:0362 inference MI:0461 interaction database YBX1 NUB1 MI:0362 inference MI:0461 interaction database TUBA1B NUB1 MI:0362 inference MI:0461 interaction database TUBA4A NUB1 MI:0362 inference MI:0461 interaction database TUBB4B NUB1 MI:0362 inference MI:0461 interaction database MRPS21 NUB1 MI:0362 inference MI:0461 interaction database RPL24 NUB1 MI:0362 inference MI:0461 interaction database RPL19 NUB1 MI:0362 inference MI:0461 interaction database HNRNPU NUB1 MI:0362 inference MI:0461 interaction database RPL18A NUB1 MI:0362 inference MI:0461 interaction database RPL6 NUB1 MI:0362 inference MI:0461 interaction database RPL18 NUB1 MI:0362 inference MI:0461 interaction database NSUN2 NUB1 MI:0362 inference MI:0461 interaction database MYO1E NUB1 MI:0362 inference MI:0461 interaction database HNRNPA0 NUB1 MI:0362 inference MI:0461 interaction database PSMD2 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database TRIM28 NUB1 MI:0362 inference MI:0461 interaction database PABPC4 NUB1 MI:0362 inference MI:0461 interaction database MRPL49 NUB1 MI:0362 inference MI:0461 interaction database TUBB3 NUB1 MI:0362 inference MI:0461 interaction database DGKZ NUB1 MI:0362 inference MI:0461 interaction database TUBA3C NUB1 MI:0362 inference MI:0461 interaction database TUBB2A NUB1 MI:0362 inference MI:0461 interaction database ICT1 NUB1 MI:0362 inference MI:0461 interaction database TRIM25 NUB1 MI:0362 inference MI:0461 interaction database FAT1 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database PLEC NUB1 MI:0362 inference MI:0461 interaction database SF3B4 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database OASL NUB1 MI:0362 inference MI:0461 interaction database NEDD8 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database HIST2H2AC NUB1 MI:0362 inference MI:0461 interaction database HIST2H2BE NUB1 MI:0362 inference MI:0461 interaction database PABPC1L NUB1 MI:0362 inference MI:0461 interaction database HSD17B12 NUB1 MI:0362 inference MI:0461 interaction database PABPC1L2A NUB1 MI:0362 inference MI:0461 interaction database RRP12 NUB1 MI:0362 inference MI:0461 interaction database HIST2H2AA3 NUB1 MI:0362 inference MI:0461 interaction database RPL22L1 NUB1 MI:0362 inference MI:0461 interaction database TUBA3E NUB1 MI:0362 inference MI:0461 interaction database TUBA1A NUB1 MI:0362 inference MI:0461 interaction database RPS27L NUB1 MI:0362 inference MI:0461 interaction database HIST3H2A NUB1 MI:0362 inference MI:0461 interaction database ZC3HAV1 NUB1 MI:0362 inference MI:0461 interaction database HUWE1 NUB1 MI:0362 inference MI:0461 interaction database MTDH NUB1 MI:0362 inference MI:0461 interaction database HIST2H2AB NUB1 MI:0362 inference MI:0461 interaction database MRPL41 NUB1 MI:0362 inference MI:0461 interaction database SRRM1 NUB1 MI:0362 inference MI:0461 interaction database RNF168 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database HIST3H2BB NUB1 MI:0362 inference MI:0461 interaction database SERBP1 NUB1 MI:0362 inference MI:0461 interaction database ANP32B NUB1 MI:0362 inference MI:0461 interaction database DDX17 NUB1 MI:0362 inference MI:0461 interaction database UFD1L NUB1 MI:0045 experimental interaction detection MI:0461 interaction database RPL3L NUB1 MI:0362 inference MI:0461 interaction database ARHGEF2 NUB1 MI:0362 inference MI:0461 interaction database HIST1H2AC NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BH NUB1 MI:0362 inference MI:0461 interaction database RPL36AL NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BA NUB1 MI:0362 inference MI:0461 interaction database PABPC5 NUB1 MI:0362 inference MI:0461 interaction database PTCD3 NUB1 MI:0362 inference MI:0461 interaction database HIST1H2AH NUB1 MI:0362 inference MI:0461 interaction database HIST1H2AA NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BN NUB1 MI:0362 inference MI:0461 interaction database HIST1H2AJ NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BM NUB1 MI:0362 inference MI:0461 interaction database HIST1H2BL NUB1 MI:0362 inference MI:0461 interaction database MYBBP1A NUB1 MI:0362 inference MI:0461 interaction database H2AFJ NUB1 MI:0362 inference MI:0461 interaction database ANP32E NUB1 MI:0362 inference MI:0461 interaction database TUBB2B NUB1 MI:0362 inference MI:0461 interaction database GNL3 NUB1 MI:0362 inference MI:0461 interaction database GTPBP4 NUB1 MI:0362 inference MI:0461 interaction database SLC25A31 NUB1 MI:0362 inference MI:0461 interaction database PABPC3 NUB1 MI:0362 inference MI:0461 interaction database ECT2 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database AGO3 NUB1 MI:0362 inference MI:0461 interaction database AGO4 NUB1 MI:0362 inference MI:0461 interaction database LUC7L NUB1 MI:0362 inference MI:0461 interaction database GNL3L NUB1 MI:0362 inference MI:0461 interaction database MRPL22 NUB1 MI:0362 inference MI:0461 interaction database AIPL1 NUB1 MI:0045 experimental interaction detection MI:0461 interaction database RRBP1 NUB1 MI:0362 inference MI:0461 interaction database SRP68 NUB1 MI:0362 inference MI:0461 interaction database AGO2 NUB1 MI:0362 inference MI:0461 interaction database MRPS7 NUB1 MI:0362 inference MI:0461 interaction database YBX2 NUB1 MI:0362 inference MI:0461 interaction database LUC7L2 NUB1 MI:0362 inference MI:0461 interaction database MRPL11 NUB1 MI:0362 inference MI:0461 interaction database NUB1 SNCAIP MI:0045 experimental interaction detection MI:0461 interaction database NUB1 OAS3 MI:0362 inference MI:0461 interaction database