Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 10 126631257 126631257 + Missense_Mutation SNP G G C TCGA-BT-A20J-01A-11D-A14W-08 TCGA-BT-A20J-11A-11D-A14W-08 g.chr10:126631257G>C c.195G>C c.(193-195)ttG>ttC p.L65F BLCA 10 126631460 126631460 + Missense_Mutation SNP C C G TCGA-XF-AAMG-01A-11D-A42E-08 TCGA-XF-AAMG-10A-01D-A42H-08 g.chr10:126631460C>G c.398C>G c.(397-399)tCt>tGt p.S133C BLCA 10 126631490 126631490 + Missense_Mutation SNP G G T TCGA-DK-A6AW-01A-11D-A30E-08 TCGA-DK-A6AW-10A-01D-A30H-08 g.chr10:126631490G>T c.428G>T c.(427-429)aGa>aTa p.R143I BLCA 10 126631753 126631753 + Nonsense_Mutation SNP C C T TCGA-DK-A3WW-01A-22D-A23M-08 TCGA-DK-A3WW-10A-01D-A23K-08 g.chr10:126631753C>T c.691C>T c.(691-693)Cag>Tag p.Q231* BLCA 10 126655268 126655268 + Missense_Mutation SNP C C G TCGA-FD-A43N-01A-11D-A23U-08 TCGA-FD-A43N-10A-01D-A23U-08 g.chr10:126655268C>G c.920C>G c.(919-921)tCt>tGt p.S307C BLCA 10 126670348 126670348 + Missense_Mutation SNP G G A TCGA-DK-A1AC-01A-11D-A13W-08 TCGA-DK-A1AC-10A-01D-A13W-08 g.chr10:126670348G>A c.1498G>A c.(1498-1500)Gaa>Aaa p.E500K BLCA 10 126672109 126672109 + Missense_Mutation SNP C C G TCGA-UY-A9PB-01A-11D-A38G-08 TCGA-UY-A9PB-10A-01D-A38J-08 g.chr10:126672109C>G c.1760C>G c.(1759-1761)tCt>tGt p.S587C BLCA 10 126672126 126672126 + Missense_Mutation SNP G G A TCGA-DK-A6AW-01A-11D-A30E-08 TCGA-DK-A6AW-10A-01D-A30H-08 g.chr10:126672126G>A c.1777G>A c.(1777-1779)Gaa>Aaa p.E593K BLCA 10 126673497 126673497 + Missense_Mutation SNP G G A TCGA-DK-A6AW-01A-11D-A30E-08 TCGA-DK-A6AW-10A-01D-A30H-08 g.chr10:126673497G>A c.2063G>A c.(2062-2064)cGa>cAa p.R688Q BRCA 10 126631661 126631661 + Missense_Mutation SNP G G T TCGA-AN-A046-01A-21W-A050-09 TCGA-AN-A046-10A-01W-A055-09 g.chr10:126631661G>T c.599G>T c.(598-600)aGa>aTa p.R200I BRCA 10 126655277 126655277 + Missense_Mutation SNP A A T TCGA-BH-A0W4-01A-11D-A10G-09 TCGA-BH-A0W4-10A-01D-A10G-09 g.chr10:126655277A>T c.929A>T c.(928-930)gAt>gTt p.D310V BRCA 10 126662834 126662834 + Missense_Mutation SNP C C G TCGA-AN-A0FX-01A-11W-A050-09 TCGA-AN-A0FX-10A-01W-A055-09 g.chr10:126662834C>G c.1294C>G c.(1294-1296)Ctg>Gtg p.L432V BRCA 10 126670316 126670316 + Missense_Mutation SNP C C A TCGA-AO-A128-01A-11D-A10M-09 TCGA-AO-A128-10A-01D-A10M-09 g.chr10:126670316C>A c.1466C>A c.(1465-1467)tCt>tAt p.S489Y BRCA 10 126671767 126671767 + Silent SNP G G A TCGA-AN-A0AK-01A-21W-A019-09 TCGA-AN-A0AK-10A-01W-A021-09 g.chr10:126671767G>A c.1572G>A c.(1570-1572)acG>acA p.T524T BRCA 10 126673446 126673446 + Missense_Mutation SNP G G A TCGA-AN-A046-01A-21W-A050-09 TCGA-AN-A046-10A-01W-A055-09 g.chr10:126673446G>A c.2012G>A c.(2011-2013)cGa>cAa p.R671Q BRCA 10 126673532 126673532 + Missense_Mutation SNP G G C TCGA-D8-A1XL-01A-11D-A14K-09 TCGA-D8-A1XL-10A-01D-A14K-09 g.chr10:126673532G>C c.2098G>C c.(2098-2100)Gag>Cag p.E700Q CESC 10 126673446 126673446 + Missense_Mutation SNP G G A TCGA-JX-A3Q0-01A-11D-A21Q-09 TCGA-JX-A3Q0-10A-01D-A21Q-09 g.chr10:126673446G>A c.2012G>A c.(2011-2013)cGa>cAa p.R671Q COAD 10 126631407 126631407 + Silent SNP T T C TCGA-A6-5661-01A-01D-1650-10 TCGA-A6-5661-10A-01D-1650-10 g.chr10:126631407T>C c.345T>C c.(343-345)agT>agC p.S115S COAD 10 126631407 126631407 + Silent SNP T T C TCGA-AY-6197-01A-11D-1719-10 TCGA-AY-6197-10A-01D-1719-10 g.chr10:126631407T>C c.345T>C c.(343-345)agT>agC p.S115S COAD 10 126631445 126631445 + Missense_Mutation SNP G G C TCGA-AA-3852-01A-01W-0900-09 TCGA-AA-3852-10A-01W-0900-09 g.chr10:126631445G>C c.383G>C c.(382-384)aGa>aCa p.R128T COAD 10 126631527 126631528 + Frame_Shift_Del DEL CT CT - TCGA-A6-3809-01A-01W-0995-10 TCGA-A6-3809-11A-01W-0995-10 g.chr10:126631527_126631528delCT c.465_466delCT c.(463-468)tgctctfs p.S156fs COAD 10 126631606 126631606 + Missense_Mutation SNP G G A TCGA-AD-6964-01A-11D-1924-10 TCGA-AD-6964-10A-01D-1924-10 g.chr10:126631606G>A c.544G>A c.(544-546)Gca>Aca p.A182T COAD 10 126631612 126631612 + Nonsense_Mutation SNP G G T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr10:126631612G>T c.550G>T c.(550-552)Gaa>Taa p.E184* COAD 10 126673350 126673350 + Missense_Mutation SNP A A G TCGA-AA-3660-01A-01D-1719-10 TCGA-AA-3660-11A-01D-1719-10 g.chr10:126673350A>G c.1916A>G c.(1915-1917)aAt>aGt p.N639S COAD 10 126673421 126673421 + Missense_Mutation SNP G G A TCGA-F4-6856-01A-11D-1924-10 TCGA-F4-6856-10A-01D-1924-10 g.chr10:126673421G>A c.1987G>A c.(1987-1989)Gcc>Acc p.A663T COADREAD 10 126631407 126631407 + Silent SNP T T C TCGA-A6-5661-01A-01D-1650-10 TCGA-A6-5661-10A-01D-1650-10 g.chr10:126631407T>C c.345T>C c.(343-345)agT>agC p.S115S COADREAD 10 126631407 126631407 + Silent SNP T T C TCGA-AY-6197-01A-11D-1719-10 TCGA-AY-6197-10A-01D-1719-10 g.chr10:126631407T>C c.345T>C c.(343-345)agT>agC p.S115S COADREAD 10 126631445 126631445 + Missense_Mutation SNP G G C TCGA-AA-3852-01A-01W-0900-09 TCGA-AA-3852-10A-01W-0900-09 g.chr10:126631445G>C c.383G>C c.(382-384)aGa>aCa p.R128T COADREAD 10 126631527 126631528 + Frame_Shift_Del DEL CT CT - TCGA-A6-3809-01A-01W-0995-10 TCGA-A6-3809-11A-01W-0995-10 g.chr10:126631527_126631528delCT c.465_466delCT c.(463-468)tgctctfs p.S156fs COADREAD 10 126631606 126631606 + Missense_Mutation SNP G G A TCGA-AD-6964-01A-11D-1924-10 TCGA-AD-6964-10A-01D-1924-10 g.chr10:126631606G>A c.544G>A c.(544-546)Gca>Aca p.A182T COADREAD 10 126631612 126631612 + Nonsense_Mutation SNP G G T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr10:126631612G>T c.550G>T c.(550-552)Gaa>Taa p.E184* COADREAD 10 126655346 126655346 + Missense_Mutation SNP C C G TCGA-AG-A00H-01A-01W-A00E-09 TCGA-AG-A00H-10A-01W-A00E-09 g.chr10:126655346C>G c.998C>G c.(997-999)aCa>aGa p.T333R COADREAD 10 126673350 126673350 + Missense_Mutation SNP A A G TCGA-AA-3660-01A-01D-1719-10 TCGA-AA-3660-11A-01D-1719-10 g.chr10:126673350A>G c.1916A>G c.(1915-1917)aAt>aGt p.N639S COADREAD 10 126673421 126673421 + Missense_Mutation SNP G G A TCGA-F4-6856-01A-11D-1924-10 TCGA-F4-6856-10A-01D-1924-10 g.chr10:126673421G>A c.1987G>A c.(1987-1989)Gcc>Acc p.A663T ESCA 10 126660624 126660624 + Missense_Mutation SNP C C A TCGA-L5-A8NE-01A-11D-A37C-09 TCGA-L5-A8NE-11A-11D-A37F-09 g.chr10:126660624C>A c.1093C>A c.(1093-1095)Cag>Aag p.Q365K ESCA 10 126671772 126671772 + Frame_Shift_Del DEL T T - TCGA-L7-A6VZ-01A-12D-A33E-09 TCGA-L7-A6VZ-10A-01D-A33H-09 g.chr10:126671772delT c.1577delT c.(1576-1578)attfs p.I526fs ESCA 10 126672121 126672121 + Missense_Mutation SNP C C T TCGA-2H-A9GJ-01A-11D-A37C-09 TCGA-2H-A9GJ-11A-11D-A37F-09 g.chr10:126672121C>T c.1772C>T c.(1771-1773)gCc>gTc p.A591V GBMLGG 10 126631286 126631286 + Missense_Mutation SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr10:126631286G>T c.224G>T c.(223-225)aGg>aTg p.R75M GBMLGG 10 126662837 126662837 + Missense_Mutation SNP T T C TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr10:126662837T>C c.1297T>C c.(1297-1299)Tat>Cat p.Y433H HNSC 10 126631073 126631073 + Missense_Mutation SNP G G C TCGA-UF-A71D-01A-12D-A34J-08 TCGA-UF-A71D-10B-01D-A34M-08 g.chr10:126631073G>C c.11G>C c.(10-12)cGt>cCt p.R4P HNSC 10 126631453 126631453 + Missense_Mutation SNP G G T TCGA-BB-A5HY-01A-11D-A28R-08 TCGA-BB-A5HY-10A-01D-A28U-08 g.chr10:126631453G>T c.391G>T c.(391-393)Gct>Tct p.A131S HNSC 10 126655286 126655286 + Missense_Mutation SNP A A G TCGA-CV-A45W-01A-11D-A25D-08 TCGA-CV-A45W-10A-01D-A25E-08 g.chr10:126655286A>G c.938A>G c.(937-939)tAt>tGt p.Y313C HNSC 10 126660540 126660540 + Missense_Mutation SNP C C G TCGA-CQ-5326-01A-01D-1870-08 TCGA-CQ-5326-10A-01D-1870-08 g.chr10:126660540C>G c.1009C>G c.(1009-1011)Caa>Gaa p.Q337E KICH 10 126631811 126631811 + Frame_Shift_Del DEL A A - TCGA-KM-8442-01A-11D-2310-10 TCGA-KM-8442-10A-01D-2311-10 g.chr10:126631811delA c.749delA c.(748-750)aaafs p.K251fs KIPAN 10 126631811 126631811 + Frame_Shift_Del DEL A A - TCGA-KM-8442-01A-11D-2310-10 TCGA-KM-8442-10A-01D-2311-10 g.chr10:126631811delA c.749delA c.(748-750)aaafs p.K251fs KIPAN 10 126662823 126662823 + Missense_Mutation SNP T T C TCGA-CZ-5453-01A-01D-1501-10 TCGA-CZ-5453-11A-01D-1501-10 g.chr10:126662823T>C c.1283T>C c.(1282-1284)tTg>tCg p.L428S KIPAN 10 126662867 126662867 + Missense_Mutation SNP T T A TCGA-B0-5095-01A-01D-1421-08 TCGA-B0-5095-11A-01D-1421-08 g.chr10:126662867T>A c.1327T>A c.(1327-1329)Tgc>Agc p.C443S KIPAN 10 126670374 126670374 + Silent SNP A A G TCGA-BP-5178-01A-01D-1429-08 TCGA-BP-5178-11A-01D-1429-08 g.chr10:126670374A>G c.1524A>G c.(1522-1524)gcA>gcG p.A508A KIPAN 10 126671767 126671767 + Silent SNP G G A TCGA-B0-4945-01A-01D-1421-08 TCGA-B0-4945-11A-01D-1421-08 g.chr10:126671767G>A c.1572G>A c.(1570-1572)acG>acA p.T524T KIRC 10 126662823 126662823 + Missense_Mutation SNP T T C TCGA-CZ-5453-01A-01D-1501-10 TCGA-CZ-5453-11A-01D-1501-10 g.chr10:126662823T>C c.1283T>C c.(1282-1284)tTg>tCg p.L428S KIRC 10 126662867 126662867 + Missense_Mutation SNP T T A TCGA-B0-5095-01A-01D-1421-08 TCGA-B0-5095-11A-01D-1421-08 g.chr10:126662867T>A c.1327T>A c.(1327-1329)Tgc>Agc p.C443S KIRC 10 126670374 126670374 + Silent SNP A A G TCGA-BP-5178-01A-01D-1429-08 TCGA-BP-5178-11A-01D-1429-08 g.chr10:126670374A>G c.1524A>G c.(1522-1524)gcA>gcG p.A508A KIRC 10 126671767 126671767 + Silent SNP G G A TCGA-B0-4945-01A-01D-1421-08 TCGA-B0-4945-11A-01D-1421-08 g.chr10:126671767G>A c.1572G>A c.(1570-1572)acG>acA p.T524T LGG 10 126631286 126631286 + Missense_Mutation SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr10:126631286G>T c.224G>T c.(223-225)aGg>aTg p.R75M LGG 10 126662837 126662837 + Missense_Mutation SNP T T C TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr10:126662837T>C c.1297T>C c.(1297-1299)Tat>Cat p.Y433H LIHC 10 126631222 126631222 + Missense_Mutation SNP G G T TCGA-CC-A8HT-01A-11D-A35Z-10 TCGA-CC-A8HT-10A-01D-A35Z-10 g.chr10:126631222G>T c.160G>T c.(160-162)Gat>Tat p.D54Y LIHC 10 126631850 126631850 + Missense_Mutation SNP A A T TCGA-MI-A75I-01A-11D-A32G-10 TCGA-MI-A75I-10A-01D-A32G-10 g.chr10:126631850A>T c.788A>T c.(787-789)gAt>gTt p.D263V LIHC 10 126655297 126655297 + Missense_Mutation SNP C C T TCGA-G3-AAUZ-01A-11D-A382-10 TCGA-G3-AAUZ-10A-01D-A385-10 g.chr10:126655297C>T c.949C>T c.(949-951)Cac>Tac p.H317Y LIHC 10 126670335 126670335 + Frame_Shift_Del DEL T T - TCGA-DD-A39Y-01A-11D-A20W-10 TCGA-DD-A39Y-11A-11D-A20W-10 g.chr10:126670335delT c.1485delT c.(1483-1485)catfs p.H495fs LUAD 10 126631393 126631393 + Missense_Mutation SNP C C T TCGA-17-Z045-01A-01W-0746-08 TCGA-17-Z045-11A-01W-0747-08 g.chr10:126631393C>T c.331C>T c.(331-333)Cgt>Tgt p.R111C LUAD 10 126631778 126631778 + Missense_Mutation SNP T T C TCGA-86-7711-01A-11D-2063-08 TCGA-86-7711-10A-01D-2063-08 g.chr10:126631778T>C c.716T>C c.(715-717)gTg>gCg p.V239A LUAD 10 126662228 126662228 + Missense_Mutation SNP C C T TCGA-17-Z050-01A-01W-0747-08 TCGA-17-Z050-11A-01W-0747-08 g.chr10:126662228C>T c.1171C>T c.(1171-1173)Ccc>Tcc p.P391S LUSC 10 126631403 126631403 + Missense_Mutation SNP G G T TCGA-18-3419-01A-01D-0983-08 TCGA-18-3419-11A-01D-0983-08 g.chr10:126631403G>T c.341G>T c.(340-342)aGg>aTg p.R114M LUSC 10 126631520 126631520 + Nonsense_Mutation SNP G G A TCGA-60-2720-01A-01D-1522-08 TCGA-60-2720-11A-01D-1522-08 g.chr10:126631520G>A c.458G>A c.(457-459)tGg>tAg p.W153* LUSC 10 126660603 126660603 + Missense_Mutation SNP G G A TCGA-22-5473-01A-01D-1632-08 TCGA-22-5473-11A-11D-1632-08 g.chr10:126660603G>A c.1072G>A c.(1072-1074)Gag>Aag p.E358K OV 10 126673350 126673350 + Missense_Mutation SNP A A G TCGA-25-2042-01A-01W-0799-08 TCGA-25-2042-10A-01W-0799-08 g.chr10:126673350A>G c.1916A>G c.(1915-1917)aAt>aGt p.N639S PAAD 10 126662279 126662279 + Missense_Mutation SNP C C A TCGA-HZ-A77Q-01A-11D-A36O-08 TCGA-HZ-A77Q-10A-01D-A367-08 g.chr10:126662279C>A c.1222C>A c.(1222-1224)Caa>Aaa p.Q408K PRAD 10 126662251 126662251 + Silent SNP A A G TCGA-YL-A8S9-01A-11D-A377-08 TCGA-YL-A8S9-10A-01D-A37A-08 g.chr10:126662251A>G c.1194A>G c.(1192-1194)ttA>ttG p.L398L PRAD 10 126662280 126662281 + Frame_Shift_Del DEL AA AA - TCGA-HC-7233-01A-11D-2114-08 TCGA-HC-7233-10A-01D-2115-08 g.chr10:126662280_126662281delAA c.1223_1224delAA c.(1222-1224)caafs p.Q408fs PRAD 10 126672053 126672053 + Silent SNP A A G TCGA-KK-A8IB-01A-11D-A364-08 TCGA-KK-A8IB-11A-11D-A362-08 g.chr10:126672053A>G c.1704A>G c.(1702-1704)gaA>gaG p.E568E READ 10 126655346 126655346 + Missense_Mutation SNP C C G TCGA-AG-A00H-01A-01W-A00E-09 TCGA-AG-A00H-10A-01W-A00E-09 g.chr10:126655346C>G c.998C>G c.(997-999)aCa>aGa p.T333R SKCM 10 126670317 126670317 + Silent SNP T T A TCGA-EE-A2A2-06A-11D-A196-08 TCGA-EE-A2A2-10A-01D-A198-08 g.chr10:126670317T>A c.1467T>A c.(1465-1467)tcT>tcA p.S489S SKCM 10 126670318 126670318 + Nonsense_Mutation SNP C C T TCGA-EE-A2A2-06A-11D-A196-08 TCGA-EE-A2A2-10A-01D-A198-08 g.chr10:126670318C>T c.1468C>T c.(1468-1470)Cag>Tag p.Q490* SKCM 10 126672076 126672076 + Missense_Mutation SNP C C T TCGA-EE-A20C-06A-11D-A196-08 TCGA-EE-A20C-10A-01D-A198-08 g.chr10:126672076C>T c.1727C>T c.(1726-1728)cCg>cTg p.P576L

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 10 126673556 126673556 single base substitution G C downstream_gene_variant BLCA-CN 10 126673556 126673556 single base substitution G C missense_variant E708Q 2122G>C BLCA-US 10 126631257 126631257 single base substitution G C missense_variant L65F 195G>C BLCA-US 10 126631753 126631753 single base substitution C T stop_gained Q231* 691C>T BLCA-US 10 126670348 126670348 single base substitution G A exon_variant BLCA-US 10 126670348 126670348 single base substitution G A missense_variant E500K 1498G>A BRCA-EU 10 126626905 126626905 single base substitution T A upstream_gene_variant BRCA-EU 10 126627098 126627098 single base substitution G A upstream_gene_variant BRCA-EU 10 126627121 126627121 single base substitution C G upstream_gene_variant BRCA-EU 10 126629584 126629584 single base substitution A C upstream_gene_variant BRCA-EU 10 126629876 126629876 single base substitution A G upstream_gene_variant BRCA-EU 10 126631423 126631423 single base substitution C T stop_gained Q121* 361C>T BRCA-EU 10 126631481 126631481 single base substitution A G missense_variant Y140C 419A>G BRCA-EU 10 126634258 126634258 single base substitution G A intron_variant BRCA-EU 10 126634352 126634352 single base substitution C T intron_variant BRCA-EU 10 126636468 126636468 single base substitution T G intron_variant BRCA-EU 10 126636487 126636487 single base substitution C T intron_variant BRCA-EU 10 126636632 126636632 single base substitution C T intron_variant BRCA-EU 10 126636642 126636642 single base substitution T A intron_variant BRCA-EU 10 126636941 126636941 single base substitution G A intron_variant BRCA-EU 10 126637751 126637751 single base substitution C T intron_variant BRCA-EU 10 126638547 126638547 single base substitution C G intron_variant BRCA-EU 10 126639359 126639359 single base substitution G C intron_variant BRCA-EU 10 126639384 126639384 single base substitution A G intron_variant BRCA-EU 10 126640342 126640342 single base substitution A G intron_variant BRCA-EU 10 126641167 126641167 single base substitution T A intron_variant BRCA-EU 10 126641610 126641610 single base substitution C T intron_variant BRCA-EU 10 126641962 126641962 single base substitution C G intron_variant BRCA-EU 10 126642055 126642055 single base substitution A T intron_variant BRCA-EU 10 126644886 126644886 single base substitution G C intron_variant BRCA-EU 10 126644973 126644973 single base substitution C G intron_variant BRCA-EU 10 126646190 126646190 single base substitution C T intron_variant BRCA-EU 10 126646672 126646672 single base substitution C T intron_variant BRCA-EU 10 126647109 126647109 deletion of <=200bp T - intron_variant BRCA-EU 10 126647109 126647110 deletion of <=200bp TT - intron_variant BRCA-EU 10 126647140 126647140 single base substitution T C intron_variant BRCA-EU 10 126649228 126649228 single base substitution G A intron_variant BRCA-EU 10 126649234 126649234 single base substitution C G intron_variant BRCA-EU 10 126649329 126649329 deletion of <=200bp A - intron_variant BRCA-EU 10 126649445 126649445 single base substitution T A intron_variant BRCA-EU 10 126651362 126651362 single base substitution C T intron_variant BRCA-EU 10 126651531 126651531 single base substitution A T intron_variant BRCA-EU 10 126651668 126651668 single base substitution C G intron_variant BRCA-EU 10 126652040 126652040 single base substitution C G intron_variant BRCA-EU 10 126652577 126652579 deletion of <=200bp CTC - intron_variant BRCA-EU 10 126652761 126652761 single base substitution C T intron_variant BRCA-EU 10 126653287 126653287 single base substitution G T intron_variant BRCA-EU 10 126653605 126653608 deletion of <=200bp TTTA - intron_variant BRCA-EU 10 126654169 126654169 deletion of <=200bp A - intron_variant BRCA-EU 10 126654775 126654775 single base substitution A C intron_variant BRCA-EU 10 126655437 126655458 deletion of <=200bp AAGCAGCTTTAAAATGTTTTGA - intron_variant BRCA-EU 10 126655458 126655458 single base substitution A T intron_variant BRCA-EU 10 126656207 126656361 deletion of <=200bp AACTTCTGCCAGAAGGGCAGAAGGGTAGCCATAGAAGGGTACCCAGAAGGGTAGCCTTAGAAATGGGAAGAGGGTTAGAGGGTTGGAGAGACTGAGACAGGCCCTCAGTCTGAAGAAGTAGACTGATTGGATATGGGAAGATACAGTGTGGATGT - intron_variant BRCA-EU 10 126656414 126656414 single base substitution T C intron_variant BRCA-EU 10 126656672 126656672 single base substitution G A intron_variant BRCA-EU 10 126657491 126657491 single base substitution G T intron_variant BRCA-EU 10 126657891 126657891 single base substitution C G intron_variant BRCA-EU 10 126658677 126658677 single base substitution T C intron_variant BRCA-EU 10 126659637 126659637 single base substitution C A intron_variant BRCA-EU 10 126660077 126660077 deletion of <=200bp T - intron_variant BRCA-EU 10 126662491 126662491 single base substitution G T intron_variant BRCA-EU 10 126663341 126663341 single base substitution C G intron_variant BRCA-EU 10 126663626 126663626 single base substitution C T intron_variant BRCA-EU 10 126663918 126663918 single base substitution A G intron_variant BRCA-EU 10 126664609 126664609 single base substitution A G intron_variant BRCA-EU 10 126665511 126665511 deletion of <=200bp T - intron_variant BRCA-EU 10 126665511 126665511 deletion of <=200bp T - upstream_gene_variant BRCA-EU 10 126668470 126668470 single base substitution C T intron_variant BRCA-EU 10 126668470 126668470 single base substitution C T upstream_gene_variant BRCA-EU 10 126668648 126668648 single base substitution A T intron_variant BRCA-EU 10 126668648 126668648 single base substitution A T upstream_gene_variant BRCA-EU 10 126669342 126669342 deletion of <=200bp T - intron_variant BRCA-EU 10 126669342 126669342 deletion of <=200bp T - upstream_gene_variant BRCA-EU 10 126669350 126669350 single base substitution T C intron_variant BRCA-EU 10 126669350 126669350 single base substitution T C upstream_gene_variant BRCA-EU 10 126670059 126670059 single base substitution A G exon_variant BRCA-EU 10 126670059 126670059 single base substitution A G intron_variant BRCA-EU 10 126670310 126670310 single base substitution G C exon_variant BRCA-EU 10 126670310 126670310 single base substitution G C missense_variant W487S 1460G>C BRCA-EU 10 126670594 126670594 single base substitution G A intron_variant BRCA-EU 10 126671153 126671153 insertion of <=200bp - T intron_variant BRCA-EU 10 126671488 126671488 single base substitution T C intron_variant BRCA-EU 10 126671924 126671924 single base substitution C T intron_variant BRCA-EU 10 126673772 126673772 deletion of <=200bp A - 3_prime_UTR_variant BRCA-EU 10 126673772 126673772 deletion of <=200bp A - downstream_gene_variant BRCA-EU 10 126674028 126674028 single base substitution C G 3_prime_UTR_variant BRCA-EU 10 126674028 126674028 single base substitution C G downstream_gene_variant BRCA-EU 10 126675055 126675055 single base substitution C A 3_prime_UTR_variant BRCA-EU 10 126675055 126675055 single base substitution C A downstream_gene_variant BRCA-EU 10 126675130 126675137 deletion of <=200bp AAAATGAT - 3_prime_UTR_variant BRCA-EU 10 126675130 126675137 deletion of <=200bp AAAATGAT - downstream_gene_variant BRCA-EU 10 126675939 126675939 insertion of <=200bp - AC 3_prime_UTR_variant BRCA-EU 10 126675939 126675939 insertion of <=200bp - AC downstream_gene_variant BRCA-EU 10 126675940 126675940 single base substitution T C 3_prime_UTR_variant BRCA-EU 10 126675940 126675940 single base substitution T C downstream_gene_variant BRCA-EU 10 126680577 126680577 single base substitution C G downstream_gene_variant BRCA-FR 10 126634258 126634258 single base substitution G A intron_variant BRCA-FR 10 126636487 126636487 single base substitution C T intron_variant BRCA-FR 10 126649234 126649234 single base substitution C G intron_variant BRCA-FR 10 126660649 126660649 single base substitution A G missense_variant Y373C 1118A>G BRCA-FR 10 126663341 126663341 single base substitution C G intron_variant BRCA-UK 10 126627098 126627098 single base substitution G A upstream_gene_variant BRCA-UK 10 126631223 126631223 single base substitution A G missense_variant D54G 161A>G BRCA-UK 10 126653287 126653287 single base substitution G T intron_variant BRCA-UK 10 126667969 126667969 single base substitution G A intron_variant BRCA-UK 10 126667969 126667969 single base substitution G A upstream_gene_variant BRCA-US 10 126631661 126631661 single base substitution G T missense_variant R200I 599G>T BRCA-US 10 126655277 126655277 single base substitution A T missense_variant D310V 929A>T BRCA-US 10 126662834 126662834 single base substitution C G missense_variant L432V 1294C>G BRCA-US 10 126670316 126670316 single base substitution C A exon_variant BRCA-US 10 126670316 126670316 single base substitution C A missense_variant S489Y 1466C>A BRCA-US 10 126671767 126671767 single base substitution G A exon_variant BRCA-US 10 126671767 126671767 single base substitution G A synonymous_variant T524T 1572G>A BRCA-US 10 126673446 126673446 single base substitution G A downstream_gene_variant BRCA-US 10 126673446 126673446 single base substitution G A missense_variant R671Q 2012G>A BRCA-US 10 126673532 126673532 single base substitution G C downstream_gene_variant BRCA-US 10 126673532 126673532 single base substitution G C missense_variant E700Q 2098G>C BRCA-US 10 126681266 126681266 single base substitution G A downstream_gene_variant BTCA-JP 10 126631639 126631639 single base substitution T C missense_variant S193P 577T>C CESC-US 10 126673446 126673446 single base substitution G A downstream_gene_variant CESC-US 10 126673446 126673446 single base substitution G A missense_variant R671Q 2012G>A CLLE-ES 10 126634153 126634153 single base substitution T C intron_variant CLLE-ES 10 126678148 126678148 single base substitution G C downstream_gene_variant COAD-US 10 126631606 126631606 single base substitution G A missense_variant A182T 544G>A COAD-US 10 126631612 126631612 single base substitution G T stop_gained E184* 550G>T COAD-US 10 126673421 126673421 single base substitution G A downstream_gene_variant COAD-US 10 126673421 126673421 single base substitution G A missense_variant A663T 1987G>A COCA-CN 10 126629768 126629768 single base substitution A T upstream_gene_variant COCA-CN 10 126631289 126631289 single base substitution T C missense_variant V76A 227T>C COCA-CN 10 126631421 126631421 single base substitution C A missense_variant P120H 359C>A COCA-CN 10 126638091 126638091 single base substitution C T intron_variant COCA-CN 10 126638549 126638549 single base substitution C G intron_variant COCA-CN 10 126641927 126641927 single base substitution G A intron_variant COCA-CN 10 126642753 126642753 single base substitution C G intron_variant COCA-CN 10 126660713 126660713 single base substitution G T intron_variant COCA-CN 10 126663080 126663080 single base substitution A G intron_variant COCA-CN 10 126667832 126667832 single base substitution A G intron_variant COCA-CN 10 126667832 126667832 single base substitution A G upstream_gene_variant COCA-CN 10 126670645 126670645 single base substitution G A intron_variant COCA-CN 10 126671767 126671767 single base substitution G A exon_variant COCA-CN 10 126671767 126671767 single base substitution G A synonymous_variant T524T 1572G>A COCA-CN 10 126671894 126671894 single base substitution G T intron_variant COCA-CN 10 126673443 126673443 single base substitution G A downstream_gene_variant COCA-CN 10 126673443 126673443 single base substitution G A missense_variant R670Q 2009G>A COCA-CN 10 126676686 126676686 single base substitution T C 3_prime_UTR_variant COCA-CN 10 126676686 126676686 single base substitution T C downstream_gene_variant COCA-CN 10 126676954 126676954 single base substitution C T downstream_gene_variant COCA-CN 10 126676988 126676988 single base substitution C A downstream_gene_variant COCA-CN 10 126677057 126677057 single base substitution G A downstream_gene_variant COCA-CN 10 126677219 126677219 single base substitution T A downstream_gene_variant COCA-CN 10 126677343 126677343 single base substitution T C downstream_gene_variant COCA-CN 10 126677434 126677434 single base substitution G A downstream_gene_variant COCA-CN 10 126677813 126677813 single base substitution T C downstream_gene_variant COCA-CN 10 126678075 126678075 single base substitution T C downstream_gene_variant COCA-CN 10 126678102 126678102 single base substitution G A downstream_gene_variant COCA-CN 10 126678177 126678177 single base substitution G T downstream_gene_variant COCA-CN 10 126678182 126678182 single base substitution G C downstream_gene_variant COCA-CN 10 126681323 126681323 single base substitution C T downstream_gene_variant ESAD-UK 10 126626239 126626239 single base substitution C T upstream_gene_variant ESAD-UK 10 126626361 126626361 single base substitution T C upstream_gene_variant ESAD-UK 10 126628144 126628144 single base substitution G C upstream_gene_variant ESAD-UK 10 126630361 126630361 insertion of <=200bp - T upstream_gene_variant ESAD-UK 10 126632918 126632918 single base substitution C A intron_variant ESAD-UK 10 126638860 126638860 single base substitution A T intron_variant ESAD-UK 10 126639088 126639088 single base substitution T G intron_variant ESAD-UK 10 126639841 126639841 single base substitution A T intron_variant ESAD-UK 10 126641168 126641168 single base substitution A T intron_variant ESAD-UK 10 126641329 126641329 single base substitution G A intron_variant ESAD-UK 10 126642595 126642595 single base substitution C T intron_variant ESAD-UK 10 126643802 126643802 single base substitution G T intron_variant ESAD-UK 10 126645760 126645760 single base substitution A G intron_variant ESAD-UK 10 126646069 126646069 single base substitution C A intron_variant ESAD-UK 10 126646783 126646783 single base substitution T C intron_variant ESAD-UK 10 126649719 126649719 single base substitution C T intron_variant ESAD-UK 10 126649792 126649792 single base substitution C T intron_variant ESAD-UK 10 126651013 126651013 insertion of <=200bp - T intron_variant ESAD-UK 10 126651511 126651511 single base substitution T C intron_variant ESAD-UK 10 126656917 126656917 single base substitution G A intron_variant ESAD-UK 10 126659644 126659644 single base substitution C T intron_variant ESAD-UK 10 126660077 126660077 deletion of <=200bp T - intron_variant ESAD-UK 10 126661518 126661518 single base substitution T A intron_variant ESAD-UK 10 126661630 126661630 single base substitution A C intron_variant ESAD-UK 10 126663977 126663977 single base substitution A G intron_variant ESAD-UK 10 126672678 126672678 single base substitution T C downstream_gene_variant ESAD-UK 10 126672678 126672678 single base substitution T C intron_variant ESAD-UK 10 126677152 126677152 single base substitution T C downstream_gene_variant ESAD-UK 10 126679302 126679317 deletion of <=200bp TGACTGGGTGAGGAAA - downstream_gene_variant ESAD-UK 10 126679435 126679435 single base substitution A T downstream_gene_variant ESCA-CN 10 126673505 126673505 single base substitution C T downstream_gene_variant ESCA-CN 10 126673505 126673505 single base substitution C T missense_variant R691W 2071C>T ESCA-CN 10 126678233 126678233 single base substitution C T downstream_gene_variant KIRC-US 10 126662823 126662823 single base substitution T C missense_variant L428S 1283T>C KIRC-US 10 126662867 126662867 single base substitution T A missense_variant C443S 1327T>A KIRC-US 10 126670374 126670374 single base substitution A G exon_variant KIRC-US 10 126670374 126670374 single base substitution A G synonymous_variant A508A 1524A>G KIRC-US 10 126671767 126671767 single base substitution G A exon_variant KIRC-US 10 126671767 126671767 single base substitution G A synonymous_variant T524T 1572G>A KIRC-US 10 126673560 126673560 insertion of <=200bp - A downstream_gene_variant KIRC-US 10 126673560 126673560 insertion of <=200bp - A frameshift_variant *709*? LAML-KR 10 126681219 126681219 single base substitution G C downstream_gene_variant LICA-CN 10 126670294 126670294 single base substitution A G exon_variant LICA-CN 10 126670294 126670294 single base substitution A G missense_variant K482E 1444A>G LICA-CN 10 126671842 126671842 single base substitution G C exon_variant LICA-CN 10 126671842 126671842 single base substitution G C synonymous_variant R549R 1647G>C LICA-FR 10 126631608 126631631 deletion of <=200bp AATAGAATTGGCAGAGACTGAAGA - disruptive_inframe_deletion AIELAETEE182A LICA-FR 10 126643016 126643016 insertion of <=200bp - T intron_variant LICA-FR 10 126645379 126645379 single base substitution A G intron_variant LICA-FR 10 126655189 126655189 single base substitution A G missense_variant I281V 841A>G LICA-FR 10 126669962 126669962 insertion of <=200bp - T intron_variant LICA-FR 10 126669962 126669962 insertion of <=200bp - T upstream_gene_variant LICA-FR 10 126672165 126672165 single base substitution C T downstream_gene_variant LICA-FR 10 126672165 126672165 single base substitution C T missense_variant L606F 1816C>T LICA-FR 10 126675691 126675691 single base substitution C T 3_prime_UTR_variant LICA-FR 10 126675691 126675691 single base substitution C T downstream_gene_variant LICA-FR 10 126678260 126678260 single base substitution G A downstream_gene_variant LICA-FR 10 126679238 126679238 single base substitution C T downstream_gene_variant LIHC-US 10 126631850 126631850 single base substitution A T missense_variant D263V 788A>T LINC-JP 10 126628758 126628758 single base substitution G A upstream_gene_variant LINC-JP 10 126631824 126631824 single base substitution A C missense_variant Q254H 762A>C LINC-JP 10 126652304 126652304 single base substitution G T intron_variant LINC-JP 10 126652943 126652943 single base substitution G C intron_variant LINC-JP 10 126657420 126657420 single base substitution T A intron_variant LINC-JP 10 126657421 126657421 single base substitution A T intron_variant LINC-JP 10 126658294 126658294 deletion of <=200bp A - intron_variant LINC-JP 10 126662303 126662303 single base substitution G T intron_variant LINC-JP 10 126662729 126662729 single base substitution T C intron_variant LINC-JP 10 126662906 126662906 single base substitution T G missense_variant Y456D 1366T>G LINC-JP 10 126664704 126664704 single base substitution T C intron_variant LINC-JP 10 126665862 126665862 single base substitution C T intron_variant LINC-JP 10 126665862 126665862 single base substitution C T upstream_gene_variant LINC-JP 10 126668299 126668299 single base substitution T C intron_variant LINC-JP 10 126668299 126668299 single base substitution T C upstream_gene_variant LINC-JP 10 126673224 126673224 single base substitution G A downstream_gene_variant LINC-JP 10 126673224 126673224 single base substitution G A intron_variant LINC-JP 10 126676916 126676916 insertion of <=200bp - T downstream_gene_variant LINC-JP 10 126677553 126677553 single base substitution C G downstream_gene_variant LINC-JP 10 126677558 126677558 single base substitution T G downstream_gene_variant LINC-JP 10 126677587 126677587 insertion of <=200bp - A downstream_gene_variant LINC-JP 10 126678246 126678246 single base substitution A G downstream_gene_variant LINC-JP 10 126678721 126678721 single base substitution C G downstream_gene_variant LIRI-JP 10 126626577 126626577 single base substitution C A upstream_gene_variant LIRI-JP 10 126627399 126627399 single base substitution C T upstream_gene_variant LIRI-JP 10 126628689 126628689 single base substitution A G upstream_gene_variant LIRI-JP 10 126629198 126629198 single base substitution A G upstream_gene_variant LIRI-JP 10 126629536 126629536 single base substitution T C upstream_gene_variant LIRI-JP 10 126629875 126629875 single base substitution A G upstream_gene_variant LIRI-JP 10 126631299 126631299 single base substitution G C synonymous_variant S79S 237G>C LIRI-JP 10 126631487 126631487 single base substitution A G missense_variant D142G 425A>G LIRI-JP 10 126632609 126632609 single base substitution T C intron_variant LIRI-JP 10 126633223 126633223 single base substitution A G intron_variant LIRI-JP 10 126635190 126635190 single base substitution A C intron_variant LIRI-JP 10 126635860 126635860 single base substitution A G intron_variant LIRI-JP 10 126637218 126637218 single base substitution T G intron_variant LIRI-JP 10 126640489 126640489 single base substitution G A intron_variant LIRI-JP 10 126640523 126640523 single base substitution C A intron_variant LIRI-JP 10 126641509 126641509 single base substitution T G intron_variant LIRI-JP 10 126642089 126642089 single base substitution A G intron_variant LIRI-JP 10 126644227 126644227 single base substitution C T intron_variant LIRI-JP 10 126646176 126646176 single base substitution A G intron_variant LIRI-JP 10 126647746 126647746 single base substitution C A intron_variant LIRI-JP 10 126647898 126647898 single base substitution T A intron_variant LIRI-JP 10 126649379 126649379 single base substitution T C intron_variant LIRI-JP 10 126649716 126649716 single base substitution G T intron_variant LIRI-JP 10 126650840 126650840 single base substitution A G intron_variant LIRI-JP 10 126654692 126654692 single base substitution A G intron_variant LIRI-JP 10 126656156 126656156 single base substitution A G intron_variant LIRI-JP 10 126656348 126656348 single base substitution T A intron_variant LIRI-JP 10 126658078 126658078 single base substitution A G intron_variant LIRI-JP 10 126658478 126658478 single base substitution A G intron_variant LIRI-JP 10 126658634 126658634 single base substitution G T intron_variant LIRI-JP 10 126660453 126660453 single base substitution G T intron_variant LIRI-JP 10 126661565 126661565 single base substitution C G intron_variant LIRI-JP 10 126664130 126664130 single base substitution G A intron_variant LIRI-JP 10 126667882 126667882 single base substitution A C intron_variant LIRI-JP 10 126667882 126667882 single base substitution A C upstream_gene_variant LIRI-JP 10 126668918 126668918 single base substitution T C intron_variant LIRI-JP 10 126668918 126668918 single base substitution T C upstream_gene_variant LIRI-JP 10 126670702 126670705 deletion of <=200bp TACA - intron_variant LIRI-JP 10 126670899 126670899 single base substitution G T intron_variant LIRI-JP 10 126671338 126671338 single base substitution A G intron_variant LIRI-JP 10 126671648 126671648 single base substitution C T intron_variant LIRI-JP 10 126673400 126673400 single base substitution A T downstream_gene_variant LIRI-JP 10 126673400 126673400 single base substitution A T missense_variant T656S 1966A>T LIRI-JP 10 126675318 126675318 single base substitution A G 3_prime_UTR_variant LIRI-JP 10 126675318 126675318 single base substitution A G downstream_gene_variant LIRI-JP 10 126678354 126678354 single base substitution A G downstream_gene_variant LIRI-JP 10 126681528 126681528 single base substitution T C downstream_gene_variant LUSC-KR 10 126632116 126632116 single base substitution A G intron_variant LUSC-KR 10 126634501 126634501 single base substitution G T intron_variant LUSC-KR 10 126636074 126636074 single base substitution A G intron_variant LUSC-KR 10 126643034 126643034 single base substitution G T intron_variant LUSC-KR 10 126643384 126643384 single base substitution A G intron_variant LUSC-KR 10 126643802 126643802 single base substitution G T intron_variant LUSC-KR 10 126652132 126652132 single base substitution T G intron_variant LUSC-KR 10 126653996 126653996 single base substitution G A intron_variant LUSC-KR 10 126668090 126668090 single base substitution C T intron_variant LUSC-KR 10 126668090 126668090 single base substitution C T upstream_gene_variant LUSC-KR 10 126676481 126676481 single base substitution C A 3_prime_UTR_variant LUSC-KR 10 126676481 126676481 single base substitution C A downstream_gene_variant LUSC-KR 10 126677382 126677382 single base substitution C A downstream_gene_variant LUSC-KR 10 126677420 126677420 single base substitution T C downstream_gene_variant LUSC-KR 10 126677425 126677425 single base substitution G T downstream_gene_variant LUSC-KR 10 126677436 126677436 single base substitution T G downstream_gene_variant LUSC-KR 10 126677472 126677472 single base substitution C T downstream_gene_variant LUSC-KR 10 126677481 126677481 single base substitution G C downstream_gene_variant LUSC-KR 10 126677501 126677501 single base substitution G A downstream_gene_variant LUSC-US 10 126631403 126631403 single base substitution G T missense_variant R114M 341G>T LUSC-US 10 126631520 126631520 single base substitution G A stop_gained W153* 458G>A LUSC-US 10 126660603 126660603 single base substitution G A missense_variant E358K 1072G>A MALY-DE 10 126626896 126626896 single base substitution A T upstream_gene_variant MALY-DE 10 126628760 126628760 single base substitution C G upstream_gene_variant MALY-DE 10 126635319 126635319 single base substitution T A intron_variant MALY-DE 10 126640015 126640015 single base substitution C G intron_variant MALY-DE 10 126644267 126644267 single base substitution A G intron_variant MALY-DE 10 126645149 126645149 single base substitution T G intron_variant MALY-DE 10 126645362 126645362 single base substitution G A intron_variant MALY-DE 10 126646452 126646452 single base substitution C T intron_variant MALY-DE 10 126654663 126654663 single base substitution T A intron_variant MALY-DE 10 126664053 126664053 single base substitution C T intron_variant MALY-DE 10 126666357 126666357 single base substitution A C intron_variant MALY-DE 10 126666357 126666357 single base substitution A C upstream_gene_variant MALY-DE 10 126671796 126671796 single base substitution G T exon_variant MALY-DE 10 126671796 126671796 single base substitution G T missense_variant R534I 1601G>T MALY-DE 10 126680488 126680488 single base substitution G A downstream_gene_variant MELA-AU 10 126626018 126626018 single base substitution G A upstream_gene_variant MELA-AU 10 126626234 126626234 single base substitution C T upstream_gene_variant MELA-AU 10 126626685 126626685 single base substitution T C upstream_gene_variant MELA-AU 10 126626822 126626822 single base substitution G A upstream_gene_variant MELA-AU 10 126627332 126627332 single base substitution G T upstream_gene_variant MELA-AU 10 126627628 126627628 single base substitution C T upstream_gene_variant MELA-AU 10 126627897 126627897 single base substitution T C upstream_gene_variant MELA-AU 10 126628316 126628316 single base substitution A T upstream_gene_variant MELA-AU 10 126628631 126628631 single base substitution C T upstream_gene_variant MELA-AU 10 126629655 126629655 single base substitution C A upstream_gene_variant MELA-AU 10 126630573 126630573 single base substitution C T upstream_gene_variant MELA-AU 10 126631264 126631265 multiple base substitution (>=2bp and <=200bp) CC TT missense_variant P68L 202CC>TT MELA-AU 10 126632898 126632898 single base substitution A G intron_variant MELA-AU 10 126633586 126633586 single base substitution T C intron_variant MELA-AU 10 126633771 126633771 single base substitution C T intron_variant MELA-AU 10 126634736 126634736 single base substitution C T intron_variant MELA-AU 10 126635413 126635414 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 10 126635867 126635867 single base substitution T A intron_variant MELA-AU 10 126637499 126637499 single base substitution C A intron_variant MELA-AU 10 126637554 126637555 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 10 126637962 126637962 single base substitution C T intron_variant MELA-AU 10 126639085 126639085 single base substitution C T intron_variant MELA-AU 10 126639733 126639733 single base substitution C T intron_variant MELA-AU 10 126640255 126640255 single base substitution G A intron_variant MELA-AU 10 126641339 126641339 single base substitution C T intron_variant MELA-AU 10 126641851 126641851 single base substitution T C intron_variant MELA-AU 10 126642014 126642014 single base substitution G A intron_variant MELA-AU 10 126642139 126642139 single base substitution C T intron_variant MELA-AU 10 126642927 126642927 single base substitution T A intron_variant MELA-AU 10 126642951 126642951 single base substitution T C intron_variant MELA-AU 10 126643220 126643220 single base substitution T C intron_variant MELA-AU 10 126644429 126644429 single base substitution C T intron_variant MELA-AU 10 126645244 126645244 single base substitution T C intron_variant MELA-AU 10 126646503 126646503 single base substitution T C intron_variant MELA-AU 10 126647483 126647483 single base substitution C T intron_variant MELA-AU 10 126647502 126647502 single base substitution C T intron_variant MELA-AU 10 126647559 126647559 single base substitution A T intron_variant MELA-AU 10 126648159 126648159 single base substitution C T intron_variant MELA-AU 10 126648975 126648975 single base substitution T C intron_variant MELA-AU 10 126649517 126649517 single base substitution C T intron_variant MELA-AU 10 126649869 126649870 multiple base substitution (>=2bp and <=200bp) CC GT intron_variant MELA-AU 10 126651812 126651812 single base substitution G A intron_variant MELA-AU 10 126651943 126651943 single base substitution C T intron_variant MELA-AU 10 126652169 126652169 single base substitution T A intron_variant MELA-AU 10 126652500 126652500 single base substitution A G intron_variant MELA-AU 10 126652668 126652668 deletion of <=200bp A - intron_variant MELA-AU 10 126653716 126653716 single base substitution G A intron_variant MELA-AU 10 126653858 126653858 single base substitution T C intron_variant MELA-AU 10 126654030 126654030 single base substitution C T intron_variant MELA-AU 10 126656564 126656564 single base substitution T C intron_variant MELA-AU 10 126656717 126656717 single base substitution C T intron_variant MELA-AU 10 126657302 126657302 single base substitution C T intron_variant MELA-AU 10 126657307 126657307 single base substitution C T intron_variant MELA-AU 10 126657638 126657638 single base substitution G A intron_variant MELA-AU 10 126657805 126657805 single base substitution A G intron_variant MELA-AU 10 126657829 126657829 single base substitution C T intron_variant MELA-AU 10 126658277 126658277 single base substitution T G intron_variant MELA-AU 10 126658332 126658332 single base substitution C T intron_variant MELA-AU 10 126661021 126661021 single base substitution C T intron_variant MELA-AU 10 126661428 126661428 single base substitution C T intron_variant MELA-AU 10 126662515 126662515 single base substitution G A intron_variant MELA-AU 10 126662728 126662728 single base substitution A C intron_variant MELA-AU 10 126662798 126662798 single base substitution T C missense_variant W420R 1258T>C MELA-AU 10 126664528 126664528 single base substitution C T intron_variant MELA-AU 10 126664751 126664751 single base substitution C T intron_variant MELA-AU 10 126666949 126666949 single base substitution T A intron_variant MELA-AU 10 126666949 126666949 single base substitution T A upstream_gene_variant MELA-AU 10 126668463 126668463 single base substitution G A intron_variant MELA-AU 10 126668463 126668463 single base substitution G A upstream_gene_variant MELA-AU 10 126668545 126668545 single base substitution A G intron_variant MELA-AU 10 126668545 126668545 single base substitution A G upstream_gene_variant MELA-AU 10 126669623 126669623 single base substitution G T intron_variant MELA-AU 10 126669623 126669623 single base substitution G T upstream_gene_variant MELA-AU 10 126670768 126670768 single base substitution C T intron_variant MELA-AU 10 126671969 126671969 single base substitution A G intron_variant MELA-AU 10 126672020 126672020 single base substitution C T intron_variant MELA-AU 10 126672020 126672020 single base substitution C T splice_region_variant MELA-AU 10 126672076 126672076 single base substitution C T downstream_gene_variant MELA-AU 10 126672076 126672076 single base substitution C T missense_variant P576L 1727C>T MELA-AU 10 126673608 126673608 single base substitution A G 3_prime_UTR_variant MELA-AU 10 126673608 126673608 single base substitution A G downstream_gene_variant MELA-AU 10 126674094 126674094 single base substitution A G 3_prime_UTR_variant MELA-AU 10 126674094 126674094 single base substitution A G downstream_gene_variant MELA-AU 10 126675560 126675560 single base substitution G A 3_prime_UTR_variant MELA-AU 10 126675560 126675560 single base substitution G A downstream_gene_variant MELA-AU 10 126679070 126679070 deletion of <=200bp A - downstream_gene_variant MELA-AU 10 126679190 126679190 single base substitution G A downstream_gene_variant MELA-AU 10 126681073 126681073 single base substitution C T downstream_gene_variant ORCA-IN 10 126673342 126673342 single base substitution G T downstream_gene_variant ORCA-IN 10 126673342 126673342 single base substitution G T splice_acceptor_variant OV-AU 10 126640491 126640491 single base substitution A G intron_variant OV-AU 10 126641758 126641758 single base substitution G A intron_variant OV-AU 10 126642459 126642459 single base substitution T C intron_variant OV-AU 10 126652596 126652596 single base substitution C T intron_variant OV-AU 10 126659416 126659416 single base substitution T G intron_variant OV-AU 10 126679338 126679338 single base substitution T C downstream_gene_variant OV-AU 10 126680268 126680268 single base substitution G A downstream_gene_variant PACA-AU 10 126628069 126628069 single base substitution A G upstream_gene_variant PACA-AU 10 126634221 126634221 single base substitution A T intron_variant PACA-AU 10 126637691 126637691 single base substitution T C intron_variant PACA-AU 10 126640354 126640354 single base substitution C T intron_variant PACA-AU 10 126648228 126648228 single base substitution G C intron_variant PACA-AU 10 126649569 126649569 insertion of <=200bp - T intron_variant PACA-AU 10 126655726 126655726 single base substitution T C intron_variant PACA-AU 10 126657505 126657505 single base substitution C T intron_variant PACA-AU 10 126664316 126664316 single base substitution A G intron_variant PACA-AU 10 126667842 126667842 single base substitution C T intron_variant PACA-AU 10 126667842 126667842 single base substitution C T upstream_gene_variant PACA-AU 10 126678128 126678128 single base substitution T A downstream_gene_variant PACA-AU 10 126678999 126679006 deletion of <=200bp AATTCATA - downstream_gene_variant PACA-AU 10 126681307 126681307 single base substitution C G downstream_gene_variant PACA-CA 10 126629098 126629098 single base substitution C T upstream_gene_variant PACA-CA 10 126631144 126631144 single base substitution C T missense_variant R28C 82C>T PACA-CA 10 126632546 126632546 single base substitution T C intron_variant PACA-CA 10 126634096 126634096 single base substitution C T intron_variant PACA-CA 10 126634737 126634737 single base substitution C T intron_variant PACA-CA 10 126640489 126640489 single base substitution G A intron_variant PACA-CA 10 126642032 126642032 single base substitution T C intron_variant PACA-CA 10 126643801 126643801 single base substitution T G intron_variant PACA-CA 10 126643802 126643802 single base substitution G T intron_variant PACA-CA 10 126645223 126645223 single base substitution T G intron_variant PACA-CA 10 126645698 126645698 single base substitution G A intron_variant PACA-CA 10 126649657 126649657 single base substitution G A intron_variant PACA-CA 10 126652014 126652014 single base substitution C A intron_variant PACA-CA 10 126653233 126653233 single base substitution G A intron_variant PACA-CA 10 126654276 126654276 single base substitution T A intron_variant PACA-CA 10 126659052 126659052 single base substitution A C intron_variant PACA-CA 10 126663186 126663186 insertion of <=200bp - T intron_variant PACA-CA 10 126663575 126663575 single base substitution C G intron_variant PACA-CA 10 126665548 126665548 insertion of <=200bp - T intron_variant PACA-CA 10 126665548 126665548 insertion of <=200bp - T upstream_gene_variant PACA-CA 10 126665990 126665990 single base substitution C T intron_variant PACA-CA 10 126665990 126665990 single base substitution C T upstream_gene_variant PACA-CA 10 126671914 126671914 single base substitution C T intron_variant PACA-CA 10 126673310 126673310 single base substitution G A downstream_gene_variant PACA-CA 10 126673310 126673310 single base substitution G A intron_variant PAEN-AU 10 126668044 126668044 single base substitution C T intron_variant PAEN-AU 10 126668044 126668044 single base substitution C T upstream_gene_variant PAEN-IT 10 126652582 126652582 single base substitution C A intron_variant PBCA-DE 10 126636986 126636986 deletion of <=200bp C - intron_variant PBCA-DE 10 126647109 126647109 deletion of <=200bp T - intron_variant PBCA-DE 10 126655303 126655303 single base substitution G C missense_variant A319P 955G>C PBCA-DE 10 126656791 126656791 single base substitution G T intron_variant PBCA-DE 10 126661811 126661811 single base substitution T C intron_variant PBCA-DE 10 126665489 126665489 single base substitution T C intron_variant PBCA-DE 10 126665489 126665489 single base substitution T C upstream_gene_variant PBCA-DE 10 126669702 126669702 single base substitution G A intron_variant PBCA-DE 10 126669702 126669702 single base substitution G A upstream_gene_variant PBCA-DE 10 126671738 126671738 single base substitution G A splice_region_variant PRAD-CA 10 126633953 126633953 single base substitution A G intron_variant PRAD-CA 10 126655243 126655243 single base substitution G A missense_variant E299K 895G>A PRAD-CA 10 126658477 126658477 single base substitution G C intron_variant PRAD-CA 10 126679329 126679329 single base substitution T C downstream_gene_variant PRAD-UK 10 126636184 126636184 single base substitution T G intron_variant PRAD-UK 10 126641224 126641224 single base substitution G C intron_variant PRAD-UK 10 126648771 126648771 single base substitution T G intron_variant PRAD-UK 10 126671508 126671508 single base substitution C T intron_variant PRAD-UK 10 126672535 126672535 single base substitution T C downstream_gene_variant PRAD-UK 10 126672535 126672535 single base substitution T C intron_variant PRAD-US 10 126662280 126662281 deletion of <=200bp AA - frameshift_variant Q408 READ-US 10 126660545 126660545 single base substitution A T missense_variant Q338H 1014A>T RECA-EU 10 126629797 126629797 single base substitution A C upstream_gene_variant RECA-EU 10 126637699 126637699 single base substitution A T intron_variant RECA-EU 10 126641599 126641599 single base substitution T G intron_variant RECA-EU 10 126651858 126651858 single base substitution A G intron_variant RECA-EU 10 126656484 126656484 single base substitution T C intron_variant RECA-EU 10 126660071 126660071 single base substitution C T intron_variant RECA-EU 10 126660072 126660072 single base substitution C T intron_variant SKCA-BR 10 126625751 126625752 deletion of <=200bp TA - upstream_gene_variant SKCA-BR 10 126632097 126632097 insertion of <=200bp - AGT intron_variant SKCA-BR 10 126633053 126633055 deletion of <=200bp TCC - intron_variant SKCA-BR 10 126633433 126633433 single base substitution C T intron_variant SKCA-BR 10 126634538 126634538 single base substitution T G intron_variant SKCA-BR 10 126638089 126638090 deletion of <=200bp CA - intron_variant SKCA-BR 10 126640729 126640729 single base substitution A C intron_variant SKCA-BR 10 126643243 126643243 single base substitution C T intron_variant SKCA-BR 10 126645234 126645234 single base substitution T G intron_variant SKCA-BR 10 126646492 126646492 single base substitution T G intron_variant SKCA-BR 10 126671152 126671152 insertion of <=200bp - CT intron_variant SKCA-BR 10 126674872 126674872 single base substitution A G 3_prime_UTR_variant SKCA-BR 10 126674872 126674872 single base substitution A G downstream_gene_variant SKCA-BR 10 126674876 126674876 single base substitution A G 3_prime_UTR_variant SKCA-BR 10 126674876 126674876 single base substitution A G downstream_gene_variant SKCA-BR 10 126674880 126674880 single base substitution A G 3_prime_UTR_variant SKCA-BR 10 126674880 126674880 single base substitution A G downstream_gene_variant SKCA-BR 10 126680766 126680766 single base substitution C T downstream_gene_variant SKCA-BR 10 126680778 126680778 insertion of <=200bp - CTT downstream_gene_variant SKCM-US 10 126670317 126670317 single base substitution T A exon_variant SKCM-US 10 126670317 126670317 single base substitution T A synonymous_variant S489S 1467T>A SKCM-US 10 126672076 126672076 single base substitution C T downstream_gene_variant SKCM-US 10 126672076 126672076 single base substitution C T missense_variant P576L 1727C>T SKCM-US 10 126678261 126678261 single base substitution C T downstream_gene_variant STAD-US 10 126631072 126631072 single base substitution C T missense_variant R4C 10C>T STAD-US 10 126631374 126631374 single base substitution T C synonymous_variant C104C 312T>C STAD-US 10 126631424 126631424 single base substitution A G missense_variant Q121R 362A>G STAD-US 10 126631559 126631559 single base substitution C A missense_variant A166D 497C>A STAD-US 10 126631810 126631810 deletion of <=200bp A - frameshift_variant K250 STAD-US 10 126660638 126660638 deletion of <=200bp T - frameshift_variant D369 STAD-US 10 126662901 126662901 single base substitution G A missense_variant G454D 1361G>A STAD-US 10 126671767 126671767 single base substitution G A exon_variant STAD-US 10 126671767 126671767 single base substitution G A synonymous_variant T524T 1572G>A STAD-US 10 126673497 126673497 single base substitution G A downstream_gene_variant STAD-US 10 126673497 126673497 single base substitution G A missense_variant R688Q 2063G>A UCEC-US 10 126631481 126631481 single base substitution A G missense_variant Y140C 419A>G UCEC-US 10 126631521 126631521 single base substitution G A stop_gained W153* 459G>A UCEC-US 10 126660593 126660593 single base substitution A G synonymous_variant Q354Q 1062A>G UCEC-US 10 126662268 126662268 single base substitution A C missense_variant D404A 1211A>C UCEC-US 10 126671865 126671865 single base substitution G A exon_variant UCEC-US 10 126671865 126671865 single base substitution G A missense_variant R557Q 1670G>A UCEC-US 10 126672204 126672204 single base substitution C G downstream_gene_variant UCEC-US 10 126672204 126672204 single base substitution C G missense_variant L619V 1855C>G UCEC-US 10 126673439 126673439 single base substitution C T downstream_gene_variant UCEC-US 10 126673439 126673439 single base substitution C T missense_variant R669W 2005C>T UCEC-US 10 126678262 126678262 single base substitution G T downstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand HCC8 COSM1603114 c.762A>C p.Q254H Substitution - Missense 10:124943255-124943255 + CHC1717T COSM4801960 c.841A>G p.I281V Substitution - Missense 10:124966620-124966620 + TCGA-HU-A4GT-01 COSM4012454 c.2063G>A p.R688Q Substitution - Missense 10:124984928-124984928 + TCGA-EE-A2A2-06 COSM3435444 c.1467T>A p.S489S Substitution - coding silent 10:124981748-124981748 + PD9585a COSM5779460 c.361C>T p.Q121* Substitution - Nonsense 10:124942854-124942854 + DN1307F COSM5962472 c.1118A>G p.Y373C Substitution - Missense 10:124972080-124972080 + SJRHB013 COSM4776478 c.1149G>T p.L383F Substitution - Missense 10:124972111-124972111 + T2269 COSM4175010 c.237G>A p.S79S Substitution - coding silent 10:124942730-124942730 + HCC127T COSM3665573 c.1366T>G p.Y456D Substitution - Missense 10:124974337-124974337 + HCT15 COSM1675639 c.411T>G p.C137W Substitution - Missense 10:124942904-124942904 + ESO-K08 COSM1271986 c.1274C>A p.A425D Substitution - Missense 10:124974245-124974245 + LAU165 COSM235610 c.702A>G p.E234E Substitution - coding silent 10:124943195-124943195 + LS174T COSM2021288 c.62C>T p.A21V Substitution - Missense 10:124942555-124942555 + TCGA-D1-A176-01 COSM915839 c.1312C>A p.R438R Substitution - coding silent 10:124974283-124974283 + PD4986a COSM5781609 c.1460G>C p.W487S Substitution - Missense 10:124981741-124981741 + TCGA-D1-A163-01 COSM915842 c.1772C>T p.A591V Substitution - Missense 10:124983552-124983552 + TCGA-EE-A20C-06 COSM3435445 c.1727C>T p.P576L Substitution - Missense 10:124983507-124983507 + TCGA-MI-A75I-01 COSM4930297 c.788A>T p.D263V Substitution - Missense 10:124943281-124943281 + PTC-7C COSM4144422 c.723C>A p.S241R Substitution - Missense 10:124943216-124943216 + EGC15 COSM5049986 c.1554A>G p.G518G Substitution - coding silent 10:124983180-124983180 + B66-Tumor COSM1745685 c.2122G>C p.E708Q Substitution - Missense 10:124984987-124984987 + TCGA-BR-4184-01 COSM4012450 c.312T>C p.C104C Substitution - coding silent 10:124942805-124942805 + PD11369a COSM915834 c.419A>G p.Y140C Substitution - Missense 10:124942912-124942912 + HCC022T COSM5817739 c.1444A>G p.K482E Substitution - Missense 10:124981725-124981725 + TCGA-BR-6452-01 COSM4012453 c.1361G>A p.G454D Substitution - Missense 10:124974332-124974332 + TCGA-BS-A0UF-01 COSM915834 c.419A>G p.Y140C Substitution - Missense 10:124942912-124942912 + LOVO COSM2021331 c.1532T>C p.L511P Substitution - Missense 10:124981813-124981813 + sysucc-1370T COSM465399 c.1572G>A p.T524T Substitution - coding silent 10:124983198-124983198 + TCGA-18-3419-01 COSM682915 c.341G>T p.R114M Substitution - Missense 10:124942834-124942834 + TCGA-AN-A0AK-01 COSM465399 c.1572G>A p.T524T Substitution - coding silent 10:124983198-124983198 + RK187_C01 COSM3741546 c.425A>G p.D142G Substitution - Missense 10:124942918-124942918 + TCGA-CA-6717-01 COSM1346589 c.550G>T p.E184* Substitution - Nonsense 10:124943043-124943043 + ccRCC-68 COSM1665309 c.24G>A p.W8* Substitution - Nonsense 10:124942517-124942517 + TCGA-D1-A163-01 COSM915841 c.1751G>T p.G584V Substitution - Missense 10:124983531-124983531 + TCGA-AA-3852-01 COSM271909 c.383G>C p.R128T Substitution - Missense 10:124942876-124942876 + UD-SCC-2 COSM1346591 c.2126_2127insA p.*709* Substitution - coding silent 10:124984991-124984992 + CHC303T COSM4950449 c.546_569del24 p.I183_E190delIELAETEE Deletion - In frame 10:124943039-124943062 + SNU-175 COSM2021338 c.1967C>T p.T656M Substitution - Missense 10:124984832-124984832 + TCGA-F5-6814-01 COSM3414790 c.1014A>T p.Q338H Substitution - Missense 10:124971976-124971976 + B66 COSM1745685 c.2122G>C p.E708Q Substitution - Missense 10:124984987-124984987 + COLO320-DM COSM2021335 c.1857G>C p.L619L Substitution - coding silent 10:124983637-124983637 + TCGA-AA-3860-01 COSM5113755 c.1796_1797insC p.R600fs*6 Insertion - Frameshift 10:124983576-124983577 + TCGA-AP-A059-01 COSM915837 c.1062A>G p.Q354Q Substitution - coding silent 10:124972024-124972024 + 61 COSM4012453 c.1361G>A p.G454D Substitution - Missense 10:124974332-124974332 + TCGA-AP-A059-01 COSM915835 c.459G>A p.W153* Substitution - Nonsense 10:124942952-124942952 + BRC28 COSM5027322 c.1368T>C p.Y456Y Substitution - coding silent 10:124974339-124974339 + TCGA-AN-A046-01 COSM1234796 c.2012G>A p.R671Q Substitution - Missense 10:124984877-124984877 + HCC151T COSM5808733 c.1647G>C p.R549R Substitution - coding silent 10:124983273-124983273 + TCGA-F4-6856-01 COSM1346590 c.1987G>A p.A663T Substitution - Missense 10:124984852-124984852 + TCGA-BH-A0W4-01 COSM427214 c.929A>T p.D310V Substitution - Missense 10:124966708-124966708 + OSCC-GB_00840111 COSM4887366 c.1909-1G>T p.? Unknown 10:124984773-124984773 + S01576 COSM4387045 c.1229-3C>T p.? Unknown 10:124974197-124974197 + CHC1717T COSM4801960 c.841A>G p.I281V Substitution - Missense 10:124966620-124966620 + TCGA-BK-A0CC-01 COSM915836 c.1025G>T p.C342F Substitution - Missense 10:124971987-124971987 + YUWAND COSM1703219 c.1894C>T p.L632F Substitution - Missense 10:124983674-124983674 + TCGA-JX-A3Q0-01 COSM1234796 c.2012G>A p.R671Q Substitution - Missense 10:124984877-124984877 + CHC303T COSM4950449 c.546_569del24 p.I183_E190delIELAETEE Deletion - In frame 10:124943039-124943062 + T3024 COSM4745361 c.2071C>T p.R691W Substitution - Missense 10:124984936-124984936 + PD2198a COSM30444 c.345T>C p.S115S Substitution - coding silent 10:124942838-124942838 + TCGA-HU-A4GU-01 COSM465399 c.1572G>A p.T524T Substitution - coding silent 10:124983198-124983198 + SNUH_G16_S1 COSM3997810 c.1506G>A p.Q502Q Substitution - coding silent 10:124981787-124981787 + TCGA-D1-A16S-01 COSM915843 c.1855C>G p.L619V Substitution - Missense 10:124983635-124983635 + TCGA-22-5473-01 COSM682913 c.1072G>A p.E358K Substitution - Missense 10:124972034-124972034 + TARGET-30-PASTKC COSM1289241 c.1561T>G p.L521V Substitution - Missense 10:124983187-124983187 + LAU165 COSM233849 c.1030C>T p.P344S Substitution - Missense 10:124971992-124971992 + CHC1763T COSM4789707 c.1816C>T p.L606F Substitution - Missense 10:124983596-124983596 + WSU-HN8 COSM1346591 c.2126_2127insA p.*709* Substitution - coding silent 10:124984991-124984992 + TCGA-BT-A20J-01 COSM415128 c.195G>C p.L65F Substitution - Missense 10:124942688-124942688 + 587220 COSM1234793 c.1646G>A p.R549Q Substitution - Missense 10:124983272-124983272 + TCGA-B5-A0JY-01 COSM915844 c.2005C>T p.R669W Substitution - Missense 10:124984870-124984870 + WA41 COSM242446 c.971G>A p.R324K Substitution - Missense 10:124966750-124966750 + CHC1763T COSM4789707 c.1816C>T p.L606F Substitution - Missense 10:124983596-124983596 + TCGA-AD-6964-01 COSM1346588 c.544G>A p.A182T Substitution - Missense 10:124943037-124943037 + TCGA-HU-A4G8-01 COSM4012452 c.497C>A p.A166D Substitution - Missense 10:124942990-124942990 + 587222 COSM1234794 c.2122G>T p.E708* Substitution - Nonsense 10:124984987-124984987 + TCGA-DK-A3WW-01 COSM3790574 c.691C>T p.Q231* Substitution - Nonsense 10:124943184-124943184 + LFS_MB4 COSM1132951 c.1549-6G>A p.? Unknown 10:124983169-124983169 + TCGA-BP-5178-01 COSM465398 c.1524A>G p.A508A Substitution - coding silent 10:124981805-124981805 + TCGA-A6-6653-01 COSM5091998 c.83G>A p.R28H Substitution - Missense 10:124942576-124942576 + 61 COSM5739071 c.2075C>T p.P692L Substitution - Missense 10:124984940-124984940 + SNU-C4 COSM4615410 c.2033_2034delAG p.Q678fs*7 Deletion - Frameshift 10:124984898-124984899 + HT55 COSM2021299 c.334A>T p.R112W Substitution - Missense 10:124942827-124942827 + CPCG0099-F1 COSM3395960 c.895G>A p.E299K Substitution - Missense 10:124966674-124966674 + PCSI_0227_Pa_P_526 COSM4962348 c.82C>T p.R28C Substitution - Missense 10:124942575-124942575 + TCGA-D8-A1XL-01 COSM1474447 c.2098G>C p.E700Q Substitution - Missense 10:124984963-124984963 + Pat_63_B COSM5836466 c.489G>A p.W163* Substitution - Nonsense 10:124942982-124942982 + TCGA-BR-4368-01 COSM4012449 c.10C>T p.R4C Substitution - Missense 10:124942503-124942503 + TCGA-AG-A00H-01 COSM265247 c.998C>G p.T333R Substitution - Missense 10:124966777-124966777 + PDA_073 COSM5001863 c.356C>A p.S119Y Substitution - Missense 10:124942849-124942849 + TCGA-AY-A54L-01 COSM5136894 c.941C>T p.T314I Substitution - Missense 10:124966720-124966720 + TCGA-BR-4184-01 COSM465399 c.1572G>A p.T524T Substitution - coding silent 10:124983198-124983198 + HCT-15 COSM1675639 c.411T>G p.C137W Substitution - Missense 10:124942904-124942904 + TCGA-AN-A0FX-01 COSM427215 c.1294C>G p.L432V Substitution - Missense 10:124974265-124974265 + TCGA-13-0717-01 COSM111578 c.2127delA p.*709fs? Deletion - Frameshift 10:124984992-124984992 + RKO COSM2021325 c.1207C>T p.L403F Substitution - Missense 10:124973695-124973695 + PD4108a COSM165956 c.161A>G p.D54G Substitution - Missense 10:124942654-124942654 + HCC8T COSM1603114 c.762A>C p.Q254H Substitution - Missense 10:124943255-124943255 + PD2198a COSM30444 c.345T>C p.S115S Substitution - coding silent 10:124942838-124942838 + PDA_066 COSM1346591 c.2126_2127insA p.*709* Substitution - coding silent 10:124984991-124984992 + SJOS002_D COSM5024076 c.968A>G p.Q323R Substitution - Missense 10:124966747-124966747 + TCGA-CZ-5453-01 COSM465396 c.1283T>C p.L428S Substitution - Missense 10:124974254-124974254 + TCGA-60-2720-01 COSM682914 c.458G>A p.W153* Substitution - Nonsense 10:124942951-124942951 + CRC-02T COSM5453709 c.359C>A p.P120H Substitution - Missense 10:124942852-124942852 + TCGA-B0-4945-01 COSM465399 c.1572G>A p.T524T Substitution - coding silent 10:124983198-124983198 + SCC-25 COSM1346591 c.2126_2127insA p.*709* Substitution - coding silent 10:124984991-124984992 + TCGA-DK-A1AC-01 COSM1297043 c.1498G>A p.E500K Substitution - Missense 10:124981779-124981779 + CPCG_0099_Pr_P_F0 COSM3395960 c.895G>A p.E299K Substitution - Missense 10:124966674-124966674 + TCGA-A6-2684-01 COSM5083006 c.271C>T p.H91Y Substitution - Missense 10:124942764-124942764 + TCGA-B0-5095-01 COSM465397 c.1327T>A p.C443S Substitution - Missense 10:124974298-124974298 + HX14T COSM1603114 c.762A>C p.Q254H Substitution - Missense 10:124943255-124943255 + 587376 COSM1234795 c.1105G>A p.D369N Substitution - Missense 10:124972067-124972067 + RK178_C01 COSM3741545 c.237G>C p.S79S Substitution - coding silent 10:124942730-124942730 + TCGA-A6-3809-01 COSM1346587 c.465_466delCT p.S156fs*5 Deletion - Frameshift 10:124942958-124942959 + TCGA-25-2042-01 COSM73505 c.1916A>G p.N639S Substitution - Missense 10:124984781-124984781 + TCGA-AP-A0LM-01 COSM915840 c.1670G>A p.R557Q Substitution - Missense 10:124983296-124983296 + CRC-19T COSM5480764 c.227T>C p.V76A Substitution - Missense 10:124942720-124942720 + 587376 COSM1234796 c.2012G>A p.R671Q Substitution - Missense 10:124984877-124984877 + HCC127 COSM3665573 c.1366T>G p.Y456D Substitution - Missense 10:124974337-124974337 + TCGA-AN-A046-01 COSM3806671 c.599G>T p.R200I Substitution - Missense 10:124943092-124943092 + ESCC_BICR_064T COSM4745361 c.2071C>T p.R691W Substitution - Missense 10:124984936-124984936 + BD124T COSM5492706 c.577T>C p.S193P Substitution - Missense 10:124943070-124943070 + V-PH-12T COSM4770353 c.15delA p.I6fs*60 Deletion - Frameshift 10:124942508-124942508 + pfg344T COSM4761112 c.1749G>T p.R583S Substitution - Missense 10:124983529-124983529 + LIM2405 COSM915842 c.1772C>T p.A591V Substitution - Missense 10:124983552-124983552 + Pat_32_B COSM5836467 c.2008C>T p.R670W Substitution - Missense 10:124984873-124984873 + TCGA-AO-A128-01 COSM3806672 c.1466C>A p.S489Y Substitution - Missense 10:124981747-124981747 + LS180 COSM2021288 c.62C>T p.A21V Substitution - Missense 10:124942555-124942555 + TCGA-AP-A059-01 COSM915838 c.1211A>C p.D404A Substitution - Missense 10:124973699-124973699 + TCGA-BR-8589-01 COSM4012451 c.362A>G p.Q121R Substitution - Missense 10:124942855-124942855 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.595156;Hs.595157;Hs.595158 10q26.13 611749

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A - 3-UTRDeletion . c.2124+12delA 10 126673561 OV - A 3-UTRInsertion . c.2124+12dupA 10 126673561 RCCC AA - Frameshift p.K409Rfs*10 c.1226_1227delAA 10 126662280 PRAD A G 3-UTRSNV . c.2124+1760A>G 10 126675318 HC A G Missense p.D54G c.161A>G 10 126631223 BRCA A G Missense p.N639S c.1916A>G 10 126673350 OV A G Synonymous p.A508A c.1524A>G 10 126670374 RCCC A T Missense p.D310V c.929A>T 10 126655277 BRCA C A Missense p.A425D c.1274C>A 10 126662814 ESCA C G Missense p.L432V c.1294C>G 10 126662834 BRCA C G Missense p.L619V c.1855C>G 10 126672204 UCEC C G Missense p.Q337E c.1009C>G 10 126660540 HNSC C G Missense p.T333R c.998C>G 10 126655346 COREAD C T Missense p.P576L c.1727C>T 10 126672076 CM C T Missense p.R111C c.331C>T 10 126631393 LUAD C T Missense p.R4C c.10C>T 10 126631072 STAD G A Missense p.E358K c.1072G>A 10 126660603 LUSC G A Nonsense p.W153* c.458G>A 10 126631520 LUSC G A Synonymous p.T524T c.1572G>A 10 126671767 RCCC G C Missense p.E700Q c.2098G>C 10 126673532 BRCA G C Missense p.L65F c.195G>C 10 126631257 BLCA G C Missense p.R128T c.383G>C 10 126631445 COREAD G T Missense p.C342F c.1025G>T 10 126660556 UCEC G T Missense p.R114M c.341G>T 10 126631403 LUSC T A Missense p.C443S c.1327T>A 10 126662867 RCCC T A Synonymous p.S489S c.1467T>A 10 126670317 CM T C Missense p.L428S c.1283T>C 10 126662823 RCCC T C Synonymous p.Y456Y c.1368T>C 10 126662908 BRCA T G Missense p.L521V c.1561T>G 10 126671756 NB