PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ELAVL1 PI4K2B 19322201 biogrid exp P P P P P P P P P P P P P P P P P P P P MAPK14 PI4K2B 16949365 biogrid exp P P P P P P P P P P P P P P P P P P P P PLAUR PI4K2B 26186194 biogrid exp P P P P P P P HSP90AA1 PI4K2B 21330372 biogrid exp P P P P P P P EFNB2 PI4K2B 26186194 biogrid exp P P P P P P P P P P P P P P P P P P P P P CASR PI4K2B 11907035 hprd exp P P CD247 PI4K2B 16337488 hprd exp P P P P PI4K2B GMPPB 26186194 biogrid exp P P P P P P P P P P P P P P P P P P P P AKT1 PI4K2B 18624398 biogrid,intact exp P P P P P P P P P P P P P P P P P P P P P SPINT2 PI4K2B 26186194 biogrid exp P P P P P P P P P P P P P P P P P P P P P PI4K2B GFOD1 26186194 biogrid exp P P P P P P P P P P P P P P P P P P P P P PI4K2B IARS2 ortho P P P P P P P P P P P P P P P P P P P P P HSPA4 PI4K2B ortho P P P P P P P P P P P P P P P P P P P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants B3KVH4 Q8TCG2 two hybrid 18624398 direct interaction X 2 P0CG48 Q8TCG2 affinity chromatography technology 22505724 physical association X 2 P0CG48 Q8TCG2 affinity chromatography technology 21963094 physical association X 2 P0CG48 Q8TCG2 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q8TCG2 affinity chromatography technology 25147182 physical association X 2 P0CG48 Q8TCG2 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q8TCG2 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q8TCG2 affinity chromatography technology 21906983 physical association X 2 Q8TCG2 Q16539-4 enzymatic study 16949365 direct interaction X 2 Q8TCG2 P07900-2 affinity chromatography technology 21330372 physical association X 2 P41180 Q8TCG2 in vivo 11907035 - X 2 P41180 Q8TCG2 in vivo 11907035 - X 2 Q8TCG2 in vivo 16337488 - X 2 Q8TCG2 in vitro 16337488 - X 2 Q8TCG2 in vivo 16337488 - X 2 Q8TCG2 in vitro 16337488 - X 2 B0LPE5 Q8TCG2 two hybrid 18624398 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality SPINT2 PI4K2B 26186194 0004 HT EFNB2 PI4K2B 26186194 0004 HT PLAUR PI4K2B 26186194 0004 HT PI4K2B GFOD1 26186194 0004 HT PI4K2B GMPPB 26186194 0004 HT SPINT2 PI4K2B 26186194 0004 HT EFNB2 PI4K2B 26186194 0004 HT PLAUR PI4K2B 26186194 0004 HT PI4K2B GFOD1 26186194 0004 HT PI4K2B GMPPB 26186194 0004 HT AKT1 PI4K2B 18624398 0018 HT MAPK14 PI4K2B 16949365 0415 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8TCG2 O43291 PI4K2B SPINT2 0.126 26186194 Q8TCG2 P07900 PI4K2B HSP90AA1 0.21 21330372 Q9NXC2 Q8TCG2 GFOD1 PI4K2B 0.126 26186194 Q9Y5P6 Q8TCG2 GMPPB PI4K2B 0.126 26186194 Q8TCG2 P31749 PI4K2B AKT1 0.332 18624398 Q8TCG2 Q15717 PI4K2B ELAVL1 0.126 19322201 Q8TCG2 Q16539 PI4K2B MAPK14 0.309 16949365 Q8TCG2 Q03405 PI4K2B PLAUR 0.126 26186194 Q8TCG2 P52799 PI4K2B EFNB2 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 WASL PI4K2B MI:0362 inference MI:0461 interaction database SPINT2 PI4K2B MI:0045 experimental interaction detection MI:0461 interaction database HSPA4L PI4K2B MI:0362 inference MI:0461 interaction database HSP90AA1 PI4K2B MI:0045 experimental interaction detection MI:0461 interaction database UBC PI4K2B MI:0045 experimental interaction detection MI:0461 interaction database HSPA1A PI4K2B MI:0362 inference MI:0461 interaction database HSPA1B PI4K2B MI:0362 inference MI:0461 interaction database HSPA8 PI4K2B MI:0362 inference MI:0461 interaction database HSPA6 PI4K2B MI:0362 inference MI:0461 interaction database RCC1 PI4K2B MI:0362 inference MI:0461 interaction database AKT1 PI4K2B MI:0045 experimental interaction detection MI:0461 interaction database HSPA1L PI4K2B MI:0362 inference MI:0461 interaction database HSPA4 PI4K2B MI:0362 inference MI:0461 interaction database EFNB2 PI4K2B MI:0045 experimental interaction detection MI:0461 interaction database HSPA2 PI4K2B MI:0362 inference MI:0461 interaction database PLAUR PI4K2B MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 PI4K2B MI:0045 experimental interaction detection MI:0461 interaction database MAPK14 PI4K2B MI:0045 experimental interaction detection MI:0461 interaction database PI4K2B HSPH1 MI:0362 inference MI:0461 interaction database PI4K2B IARS2 MI:0362 inference MI:0461 interaction database PI4K2B GFOD1 MI:0045 experimental interaction detection MI:0461 interaction database PI4K2B ONECUT1 MI:0045 experimental interaction detection MI:0461 interaction database PI4K2B GMPPB MI:0045 experimental interaction detection MI:0461 interaction database