PTM - CPLM Gene Name UniProt ID Type Position Code UFD1L Q92890 Ubiquitination 264 K UFD1L Q92890 Ubiquitination 303 K UFD1L Q92890 Ubiquitination 45 K UFD1L Q92890 Ubiquitination 72 K UFD1L Q92890 Ubiquitination 139 K UFD1L Q92890 Ubiquitination 175 K UFD1L Q92890 Ubiquitination 279 K UFD1L Q92890 Ubiquitination 68 K UFD1L Q92890 Ubiquitination 178 K UFD1L Q92890 Ubiquitination 267 K UFD1L Q92890 Ubiquitination 250 K

PTM - dbPAF Gene Name UniProt ID Position Type Species UFD1L Q92890 129 S Homo sapiens(Human) UFD1L Q92890 136 T Homo sapiens(Human) UFD1L Q92890 167 Y Homo sapiens(Human) UFD1L Q92890 209 S Homo sapiens(Human) UFD1L Q92890 210 T Homo sapiens(Human) UFD1L Q92890 217 S Homo sapiens(Human) UFD1L Q92890 219 Y Homo sapiens(Human) UFD1L Q92890 229 S Homo sapiens(Human) UFD1L Q92890 231 S Homo sapiens(Human) UFD1L Q92890 245 S Homo sapiens(Human) UFD1L Q92890 247 S Homo sapiens(Human) UFD1L Q92890 261 Y Homo sapiens(Human) UFD1L Q92890 27 S Homo sapiens(Human) UFD1L Q92890 29 S Homo sapiens(Human) UFD1L Q92890 294 S Homo sapiens(Human) UFD1L Q92890 299 S Homo sapiens(Human) UFD1L Q92890 3 S Homo sapiens(Human) UFD1L Q92890 78 T Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q92890 K238-ac Acetylation sGNRLDGkKKGVEPs Q92890 K250-ac Acetylation EPsPsPIkPGDIkRG Q92890 R170-m1 Methylation NEkIYELrVMETkPD Q92890 S3-p Phosphorylation _____MFsFNMFDHP Q92890 S27-p Phosphorylation STQYRCFsVsMLAGP Q92890 S29-p Phosphorylation QYRCFsVsMLAGPND Q92890 T78-p Phosphorylation NkNSDRMtHCGVLEF Q92890 S129-p Phosphorylation YSkFQPQsPDFLDIt Q92890 T136-p Phosphorylation sPDFLDItNPkAVLE Q92890 S209-p Phosphorylation RQVQHEEstEGEADH Q92890 T210-p Phosphorylation QVQHEEstEGEADHs Q92890 S217-p Phosphorylation tEGEADHsGyAGELG Q92890 Y219-p Phosphorylation GEADHsGyAGELGFR Q92890 S229-p Phosphorylation ELGFRAFsGsGNRLD Q92890 S231-p Phosphorylation GFRAFsGsGNRLDGk Q92890 S245-p Phosphorylation kKKGVEPsPsPIkPG Q92890 S247-p Phosphorylation KGVEPsPsPIkPGDI Q92890 Y261-p Phosphorylation IkRGIPNyEFkLGkI Q92890 S294-p Phosphorylation GGRFVAFsGEGQsLR Q92890 S299-p Phosphorylation AFsGEGQsLRKKGRK Q92890 K45-ub Ubiquitination SDVEKGGkIIMPPSA Q92890 K68-ub Ubiquitination ITYPMLFkLTNkNSD Q92890 K72-ub Ubiquitination MLFkLTNkNSDRMtH Q92890 K124-ub Ubiquitination LQVATYSkFQPQsPD Q92890 K139-ub Ubiquitination FLDItNPkAVLENAL Q92890 K165-ub Ubiquitination IAINYNEkIYELrVM Q92890 K175-ub Ubiquitination ELrVMETkPDkAVSI Q92890 K178-ub Ubiquitination VMETkPDkAVSIIEC Q92890 K198-ub Ubiquitination FDAPLGYkEPERQVQ Q92890 K250-ub Ubiquitination EPsPsPIkPGDIkRG Q92890 K255-ub Ubiquitination PIkPGDIkRGIPNyE Q92890 K264-ub Ubiquitination GIPNyEFkLGkITFI Q92890 K267-ub Ubiquitination NyEFkLGkITFIRNS Q92890 K279-ub Ubiquitination RNSRPLVkKVEEDEA

PTM - dbPTM UniProt ID Position Code Type Resources References Q92890 1 M Acetylation Swiss-Prot 1010711 19413330 Q92890 245 S Phosphorylation Swiss-Prot 1010711 18669648 Q92890 247 S Phosphorylation Swiss-Prot 1010711 17924679;18669648 Q92890 299 S Phosphorylation Swiss-Prot 1010711 17287340;18669648;19367720;19690332 Q92890 299 S Phosphorylation PhosphoELM.10011 18669648;17287340 Q92890 245 S Phosphorylation PhosphoELM.10011 18669648 Q92890 247 S Phosphorylation PhosphoELM.10011 18669648 Q92890 139 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92890 175 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92890 264 K Ubiquitylation Phosphositeplus.1010730 21890473 Q92890 267 K Ubiquitylation Phosphositeplus.1010730 21890473 Q92890 279 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92890 45 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92890 72 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92890 231 S Phosphorylation Phosphositeplus.1010730 20068231 Q92890 245 S Phosphorylation Phosphositeplus.1010730 18669648;20068231;20363803 Q92890 247 S Phosphorylation Phosphositeplus.1010730 17446864;18669648;19276368;19362540;20068231;20363803;20562096;21406692;21659604;22115753 Q92890 299 S Phosphorylation Phosphositeplus.1010730 17287340;18491316;18669648;19367720;19415658;19664994;19664995;19690332;20068231;20166139;20363803;20815410;21406692 Q92890 167 Y Phosphorylation Phosphositeplus.1010730 18083107 Q92890 231 S Phosphorylation HPRD 9.0 20068231 Q92890 245 S Phosphorylation HPRD 9.0 18669648,19651622,20068231 Q92890 247 S Phosphorylation HPRD 9.0 17322306,18669648,17924679,19651622,20068231 Q92890 299 S Phosphorylation HPRD 9.0 18669648,19415658,17287340,18491316,19664995,19664994,18767875,20166139,20068231 Q92890 210 T Phosphorylation HPRD 9.0 20068231 Q92890 245 S Phosphorylation SysPTM 1.1 18669648 Q92890 247 S Phosphorylation SysPTM 1.1 18669648 Q92890 299 S Phosphorylation SysPTM 1.1 18491316;18669648

PTM - HPRD Symbol Position Code Type References UFD1L 210 T Phosphorylation 20068231 UFD1L 231 S Phosphorylation 20068231 UFD1L 245 S Phosphorylation 18669648,19651622,20068231 UFD1L 247 S Phosphorylation 17322306,18669648,17924679,19651622,20068231 UFD1L 299 S Phosphorylation 18669648,19415658,17287340,18491316,19664995,19664994,18767875,20166139,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q92890 283 S 18669648 HTP Phosphorylation Q92890 335 S 18669648 HTP Phosphorylation Q92890 335 S 17287340 HTP Phosphorylation Q92890 281 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q92890 1 N-acetylmethionine 19413330 Q92890 129 Phosphoserine 23186163 Q92890 231 Phosphoserine 20068231;23186163 Q92890 245 Phosphoserine 20068231;23186163 Q92890 247 Phosphoserine 20068231;23186163 Q92890 299 Phosphoserine 18669648;19690332;20068231;21406692;23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type UFD1L IPI00218292 S 231 FRAFSGpSGNRLDG phosphorylation UFD1L IPI00218292 S 245 KKGVEPpSPSPIKP phosphorylation UFD1L IPI00218292 S 247 GVEPSPpSPIKPGD phosphorylation UFD1L IPI00218292 S 299 FSGEGQpSLRKKGR phosphorylation UFD1L IPI00218292 S 3 ____MFpSFNMFDH phosphorylation UFD1L IPI00218292 T 210 VQHEESpTEGEADH phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 7353 113200 - K Ubiquitination 18781797 7353 113200 - K Ubiquitination 21987572 7353 113200 - K Ubiquitination 21139048 7353 113200 - K Ubiquitination 21890473 7353 113200 - K Ubiquitination 21906983 7353 113200 - K Ubiquitination 22053931 7353 113200 - K Ubiquitination 22505724 7353 113200 - K Ubiquitination 21963094 7353 113200 - K Ubiquitination 23000965 7353 113200 - K Ubiquitination 24816145 7353 113200 - K Sumoylation 25391492

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID UFD1L Homo sapiens (Human) 256; 253 "256,YEFKLGKITFIRN; 253,IPNYEFKLGKITF" 256:21890473; 253:21890473 UFD1L Homo sapiens (Human) 139; 175; 279; 178; 267; 264; 72; 45 "139,LDITNPKAVLENA; 175,LRVMETKPDKAVS; 279,NSRPLVKKVEEDE; 178,METKPDKAVSIIE; 267,YEFKLGKITFIRN; 264,IPNYEFKLGKITF; 72,LFKLTNKNSDRMT; 45,DVEKGGKIIMPPS" "139:21906983; 175:21906983,22053931; 279:21906983; 178:22053931; 267:21890473; 264:21890473,22053931; 72:21906983,22053931; 45:21906983" UFD1L Homo sapiens (Human) 175; 315; 72; 300; 45; 211; 303 "175,LDITNPKAVLENA; 315,NSRPLVKKVEEDE; 72,LFKLTNKNSDRMT; 300,IPNYEFKLGKITF; 45,DVEKGGKIIMPPS; 211,LRVMETKPDKAVS; 303,YEFKLGKITFIRN" 175:21906983; 315:21906983; 72:21906983; 300:21890473; 45:21906983; 211:21906983; 303:21890473 UFD1L Homo sapiens (Human) 139; 175; 279; 267; 264; 72; 45 "139,LDITNPKAVLENA; 175,LRVMETKPDKAVS; 279,NSRPLVKKVEEVS; 267,YEFKLGKITFIRN; 264,IPNYEFKLGKITF; 72,LFKLTNKNSDRMT; 45,DVEKGGKIIMPPS" 139:21906983; 175:21906983; 279:21906983; 267:21890473; 264:21890473; 72:21906983; 45:21906983 UFD1L Homo sapiens (Human) 256; 253 "256,YEFKLGKITFIRN; 253,IPNYEFKLGKITF" "256:21906983,21890473; 253:21906983,21890473" UFD1L Homo sapiens (Human) 267; 264 "267,YEFKLGKITFIRN; 264,IPNYEFKLGKITF" 267:21890473; 264:21890473 UFD1L Homo sapiens (Human) 300; 303 "300,IPNYEFKLGKITF; 303,YEFKLGKITFIRN" 300:21890473; 303:21890473 UFD1L Homo sapiens (Human) 139; 175; 267; 264; 72; 45 "139,LDITNPKAVLENA; 175,LRVMETKPDKAVS; 267,YEFKLGKITFIRN; 264,IPNYEFKLGKITF; 72,LFKLTNKNSDRMT; 45,DVEKGGKIIMPPS" 139:21906983; 175:21906983; 267:21890473; 264:21890473; 72:21906983; 45:21906983 UFD1L Homo sapiens (Human) 139; 175; 279; 178; 264; 72 "139,LDITNPKAVLENA; 175,LRVMETKPDKAVS; 279,NSRPLVKKVEEDE; 178,METKPDKAVSIIE; 264,IPNYEFKLGKITF; 72,LFKLTNKNSDRMT" "139:21906983; 175:21906983,22053931; 279:21906983; 178:22053931; 264:22053931; 72:21906983,22053931" UFD1L Homo sapiens (Human) 67 "67,LFKLTNKNSDRMT" 67:21906983