Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 10 60123412 60123412 + Missense_Mutation SNP A A G TCGA-ZF-A9R9-01A-11D-A38G-08 TCGA-ZF-A9R9-10A-01D-A38J-08 g.chr10:60123412A>G c.164A>G c.(163-165)cAt>cGt p.H55R BLCA 10 60123418 60123418 + Missense_Mutation SNP C C G TCGA-XF-A9SK-01A-11D-A42E-08 TCGA-XF-A9SK-10A-01D-A42H-08 g.chr10:60123418C>G c.170C>G c.(169-171)cCg>cGg p.P57R BRCA 10 60127761 60127761 + Missense_Mutation SNP A A C TCGA-AN-A046-01A-21W-A050-09 TCGA-AN-A046-10A-01W-A055-09 g.chr10:60127761A>C c.383A>C c.(382-384)aAa>aCa p.K128T CESC 10 60127703 60127703 + Missense_Mutation SNP C C G TCGA-EA-A3HU-01A-11D-A20U-09 TCGA-EA-A3HU-10B-01D-A20U-09 g.chr10:60127703C>G c.325C>G c.(325-327)Cta>Gta p.L109V COAD 10 60123413 60123413 + Frame_Shift_Del DEL T T - TCGA-AA-A022-01A-21W-A096-10 TCGA-AA-A022-11A-11W-A096-10 g.chr10:60123413delT c.165delT c.(163-165)catfs p.H55fs COADREAD 10 60123413 60123413 + Frame_Shift_Del DEL T T - TCGA-AA-A022-01A-21W-A096-10 TCGA-AA-A022-11A-11W-A096-10 g.chr10:60123413delT c.165delT c.(163-165)catfs p.H55fs ESCA 10 60121256 60121256 + Splice_Site SNP G G T TCGA-L5-A4OP-01A-11D-A27G-09 TCGA-L5-A4OP-11A-11D-A27G-09 g.chr10:60121256G>T c.90G>T c.(88-90)ttG>ttT p.L30F ESCA 10 60124623 60124623 + Silent SNP G G T TCGA-R6-A8W5-01B-11D-A37C-09 TCGA-R6-A8W5-10A-01D-A37F-09 g.chr10:60124623G>T c.291G>T c.(289-291)ctG>ctT p.L97L KIPAN 10 60124536 60124536 + Silent SNP T T A TCGA-EU-5906-01A-11D-1669-08 TCGA-EU-5906-10A-01D-1669-08 g.chr10:60124536T>A c.204T>A c.(202-204)gcT>gcA p.A68A KIPAN 10 60128479 60128479 + Splice_Site SNP G G T TCGA-CZ-5987-01A-11D-1669-08 TCGA-CZ-5987-11A-01D-1669-08 g.chr10:60128479G>T c.e7-1 KIPAN 10 60128517 60128517 + Missense_Mutation SNP G G C TCGA-CZ-5455-01A-01D-1501-10 TCGA-CZ-5455-11A-01D-1501-10 g.chr10:60128517G>C c.436G>C c.(436-438)Gca>Cca p.A146P KIRC 10 60124536 60124536 + Silent SNP T T A TCGA-EU-5906-01A-11D-1669-08 TCGA-EU-5906-10A-01D-1669-08 g.chr10:60124536T>A c.204T>A c.(202-204)gcT>gcA p.A68A KIRC 10 60128479 60128479 + Splice_Site SNP G G T TCGA-CZ-5987-01A-11D-1669-08 TCGA-CZ-5987-11A-01D-1669-08 g.chr10:60128479G>T c.e7-1 KIRC 10 60128517 60128517 + Missense_Mutation SNP G G C TCGA-CZ-5455-01A-01D-1501-10 TCGA-CZ-5455-11A-01D-1501-10 g.chr10:60128517G>C c.436G>C c.(436-438)Gca>Cca p.A146P LIHC 10 60123367 60123367 + Splice_Site SNP A A G TCGA-CC-A3MA-01A-11D-A20W-10 TCGA-CC-A3MA-10A-01D-A20W-10 g.chr10:60123367A>G c.e4-1 LUAD 10 60123428 60123428 + Silent SNP T T C TCGA-55-7570-01A-11D-2036-08 TCGA-55-7570-10A-01D-2036-08 g.chr10:60123428T>C c.180T>C c.(178-180)taT>taC p.Y60Y LUAD 10 60124575 60124575 + Silent SNP T T C TCGA-05-4420-01A-01D-1265-08 TCGA-05-4420-10A-01D-1265-08 g.chr10:60124575T>C c.243T>C c.(241-243)aaT>aaC p.N81N LUAD 10 60124613 60124613 + Nonsense_Mutation SNP C C G TCGA-95-7039-01A-11D-1945-08 TCGA-95-7039-10A-01D-1946-08 g.chr10:60124613C>G c.281C>G c.(280-282)tCa>tGa p.S94* LUSC 10 60124635 60124635 + Splice_Site SNP A A T TCGA-33-4533-01A-01D-1267-08 TCGA-33-4533-11A-01D-1267-08 g.chr10:60124635A>T c.303A>T c.(301-303)aaA>aaT p.K101N PAAD 10 60121147 60121147 + Missense_Mutation SNP C C A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr10:60121147C>A c.74C>A c.(73-75)cCt>cAt p.P25H SKCM 10 60123403 60123403 + Missense_Mutation SNP T T C TCGA-ER-A193-06A-12D-A197-08 TCGA-ER-A193-10A-01D-A199-08 g.chr10:60123403T>C c.155T>C c.(154-156)cTc>cCc p.L52P SKCM 10 60124590 60124590 + Silent SNP C C T TCGA-FS-A1ZZ-06A-11D-A197-08 TCGA-FS-A1ZZ-10A-01D-A199-08 g.chr10:60124590C>T c.258C>T c.(256-258)ctC>ctT p.L86L

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BOCA-FR 10 60117713 60117713 single base substitution C T intron_variant BRCA-EU 10 60090329 60090329 single base substitution C T upstream_gene_variant BRCA-EU 10 60090428 60090428 single base substitution G A upstream_gene_variant BRCA-EU 10 60091058 60091058 single base substitution G T upstream_gene_variant BRCA-EU 10 60091257 60091257 single base substitution C T upstream_gene_variant BRCA-EU 10 60092251 60092251 single base substitution C T upstream_gene_variant BRCA-EU 10 60093262 60093262 single base substitution G A upstream_gene_variant BRCA-EU 10 60095688 60095688 deletion of <=200bp T - intron_variant BRCA-EU 10 60097236 60097236 single base substitution T C intron_variant BRCA-EU 10 60098735 60098735 single base substitution G A intron_variant BRCA-EU 10 60101185 60101185 deletion of <=200bp T - intron_variant BRCA-EU 10 60101351 60101351 single base substitution G T intron_variant BRCA-EU 10 60101414 60101414 single base substitution T A intron_variant BRCA-EU 10 60101558 60101558 single base substitution A G intron_variant BRCA-EU 10 60102105 60102105 deletion of <=200bp T - intron_variant BRCA-EU 10 60102105 60102105 insertion of <=200bp - T intron_variant BRCA-EU 10 60102328 60102328 single base substitution A T intron_variant BRCA-EU 10 60103024 60103024 deletion of <=200bp T - intron_variant BRCA-EU 10 60103489 60103489 single base substitution C G intron_variant BRCA-EU 10 60105338 60105338 single base substitution C T intron_variant BRCA-EU 10 60105622 60105622 single base substitution G A intron_variant BRCA-EU 10 60105849 60105849 single base substitution C T intron_variant BRCA-EU 10 60108038 60108038 single base substitution C G intron_variant BRCA-EU 10 60108706 60108706 single base substitution A C intron_variant BRCA-EU 10 60109395 60109395 single base substitution G C intron_variant BRCA-EU 10 60111582 60111582 single base substitution C A intron_variant BRCA-EU 10 60112394 60112394 single base substitution T C intron_variant BRCA-EU 10 60113929 60113929 single base substitution G A intron_variant BRCA-EU 10 60115859 60115859 single base substitution C G intron_variant BRCA-EU 10 60116163 60116163 insertion of <=200bp - AT intron_variant BRCA-EU 10 60119197 60119197 single base substitution G T intron_variant BRCA-EU 10 60119209 60119209 single base substitution C T intron_variant BRCA-EU 10 60119666 60119666 single base substitution C G intron_variant BRCA-EU 10 60119666 60119666 single base substitution C G upstream_gene_variant BRCA-EU 10 60121095 60121095 single base substitution C T splice_region_variant BRCA-EU 10 60121095 60121095 single base substitution C T upstream_gene_variant BRCA-EU 10 60122216 60122216 single base substitution A G intron_variant BRCA-EU 10 60122216 60122216 single base substitution A G upstream_gene_variant BRCA-EU 10 60122360 60122360 single base substitution G C intron_variant BRCA-EU 10 60122360 60122360 single base substitution G C upstream_gene_variant BRCA-EU 10 60123765 60123765 single base substitution T G intron_variant BRCA-EU 10 60123765 60123765 single base substitution T G upstream_gene_variant BRCA-EU 10 60124539 60124539 single base substitution C T exon_variant BRCA-EU 10 60124539 60124539 single base substitution C T synonymous_variant F69F 207C>T BRCA-EU 10 60124539 60124539 single base substitution C T upstream_gene_variant BRCA-EU 10 60125775 60125775 single base substitution C T intron_variant BRCA-EU 10 60125775 60125775 single base substitution C T upstream_gene_variant BRCA-EU 10 60126026 60126026 single base substitution A C intron_variant BRCA-EU 10 60126026 60126026 single base substitution A C upstream_gene_variant BRCA-EU 10 60126071 60126071 single base substitution C G intron_variant BRCA-EU 10 60126071 60126071 single base substitution C G upstream_gene_variant BRCA-EU 10 60127289 60127289 single base substitution C G intron_variant BRCA-EU 10 60127289 60127289 single base substitution C G upstream_gene_variant BRCA-EU 10 60127496 60127496 single base substitution T C intron_variant BRCA-EU 10 60127496 60127496 single base substitution T C upstream_gene_variant BRCA-EU 10 60129659 60129659 single base substitution A G 3_prime_UTR_variant BRCA-EU 10 60129659 60129659 single base substitution A G downstream_gene_variant BRCA-EU 10 60129689 60129689 single base substitution C A 3_prime_UTR_variant BRCA-EU 10 60129689 60129689 single base substitution C A downstream_gene_variant BRCA-EU 10 60131200 60131200 single base substitution C G downstream_gene_variant BRCA-EU 10 60131792 60131792 single base substitution T G downstream_gene_variant BRCA-EU 10 60132050 60132050 single base substitution C T downstream_gene_variant BRCA-EU 10 60133329 60133329 single base substitution G A downstream_gene_variant BRCA-EU 10 60134844 60134844 single base substitution G A downstream_gene_variant BRCA-FR 10 60101414 60101414 single base substitution T A intron_variant BRCA-FR 10 60103489 60103489 single base substitution C G intron_variant BRCA-UK 10 60101067 60101067 single base substitution C T intron_variant BRCA-UK 10 60108706 60108706 single base substitution A C intron_variant BRCA-UK 10 60111582 60111582 single base substitution C A intron_variant BRCA-UK 10 60134401 60134401 single base substitution C T downstream_gene_variant BRCA-US 10 60127761 60127761 single base substitution A C exon_variant BRCA-US 10 60127761 60127761 single base substitution A C missense_variant K128T 383A>C BRCA-US 10 60127761 60127761 single base substitution A C upstream_gene_variant BTCA-JP 10 60127639 60127639 single base substitution G T intron_variant BTCA-JP 10 60127639 60127639 single base substitution G T upstream_gene_variant BTCA-JP 10 60127838 60127838 single base substitution G A intron_variant BTCA-JP 10 60127838 60127838 single base substitution G A upstream_gene_variant CESC-US 10 60127703 60127703 single base substitution C G exon_variant CESC-US 10 60127703 60127703 single base substitution C G missense_variant L109V 325C>G CESC-US 10 60127703 60127703 single base substitution C G upstream_gene_variant COCA-CN 10 60098779 60098779 single base substitution A T intron_variant COCA-CN 10 60103139 60103139 single base substitution A C intron_variant COCA-CN 10 60123486 60123486 single base substitution A G intron_variant COCA-CN 10 60123486 60123486 single base substitution A G upstream_gene_variant COCA-CN 10 60126263 60126263 single base substitution C G intron_variant COCA-CN 10 60126263 60126263 single base substitution C G upstream_gene_variant COCA-CN 10 60127639 60127639 single base substitution G T intron_variant COCA-CN 10 60127639 60127639 single base substitution G T upstream_gene_variant COCA-CN 10 60130424 60130424 single base substitution A C 3_prime_UTR_variant COCA-CN 10 60130424 60130424 single base substitution A C downstream_gene_variant ESAD-UK 10 60089747 60089747 single base substitution A T upstream_gene_variant ESAD-UK 10 60091327 60091327 single base substitution C G upstream_gene_variant ESAD-UK 10 60092333 60092333 single base substitution C T upstream_gene_variant ESAD-UK 10 60094749 60094749 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant ESAD-UK 10 60094805 60094805 single base substitution A G 5_prime_UTR_variant ESAD-UK 10 60095023 60095023 single base substitution G A intron_variant ESAD-UK 10 60097180 60097180 single base substitution C A intron_variant ESAD-UK 10 60098735 60098735 single base substitution G C intron_variant ESAD-UK 10 60098871 60098871 insertion of <=200bp - T intron_variant ESAD-UK 10 60101466 60101466 single base substitution A G intron_variant ESAD-UK 10 60101532 60101532 single base substitution T C intron_variant ESAD-UK 10 60101577 60101577 single base substitution A G intron_variant ESAD-UK 10 60101695 60101695 single base substitution T C intron_variant ESAD-UK 10 60103508 60103508 single base substitution T C intron_variant ESAD-UK 10 60105069 60105069 single base substitution A T intron_variant ESAD-UK 10 60105317 60105317 single base substitution A C intron_variant ESAD-UK 10 60105345 60105345 single base substitution A C intron_variant ESAD-UK 10 60106363 60106363 single base substitution A G intron_variant ESAD-UK 10 60106907 60106907 single base substitution C T intron_variant ESAD-UK 10 60107039 60107039 single base substitution G C intron_variant ESAD-UK 10 60107462 60107462 single base substitution C A intron_variant ESAD-UK 10 60107705 60107705 single base substitution G A intron_variant ESAD-UK 10 60110419 60110419 single base substitution T C intron_variant ESAD-UK 10 60111867 60111867 single base substitution G A intron_variant ESAD-UK 10 60112201 60112201 single base substitution A G intron_variant ESAD-UK 10 60112967 60112967 single base substitution T A intron_variant ESAD-UK 10 60113539 60113539 single base substitution C T intron_variant ESAD-UK 10 60115289 60115289 single base substitution A G intron_variant ESAD-UK 10 60116021 60116021 single base substitution C T intron_variant ESAD-UK 10 60119819 60119819 single base substitution C T intron_variant ESAD-UK 10 60119819 60119819 single base substitution C T upstream_gene_variant ESAD-UK 10 60122803 60122803 insertion of <=200bp - T intron_variant ESAD-UK 10 60122803 60122803 insertion of <=200bp - T upstream_gene_variant ESAD-UK 10 60123770 60123770 single base substitution A C intron_variant ESAD-UK 10 60123770 60123770 single base substitution A C upstream_gene_variant ESAD-UK 10 60124306 60124306 single base substitution C T exon_variant ESAD-UK 10 60124306 60124306 single base substitution C T intron_variant ESAD-UK 10 60124306 60124306 single base substitution C T upstream_gene_variant ESAD-UK 10 60125451 60125451 single base substitution T G intron_variant ESAD-UK 10 60125451 60125451 single base substitution T G upstream_gene_variant ESAD-UK 10 60127514 60127514 single base substitution A G intron_variant ESAD-UK 10 60127514 60127514 single base substitution A G upstream_gene_variant ESAD-UK 10 60128156 60128156 single base substitution A G exon_variant ESAD-UK 10 60128156 60128156 single base substitution A G intron_variant ESAD-UK 10 60131768 60131768 single base substitution G T downstream_gene_variant ESAD-UK 10 60132478 60132478 single base substitution G A downstream_gene_variant ESAD-UK 10 60134088 60134088 deletion of <=200bp T - downstream_gene_variant ESAD-UK 10 60134555 60134555 single base substitution G A downstream_gene_variant ESAD-UK 10 60134572 60134572 single base substitution A G downstream_gene_variant ESAD-UK 10 60134921 60134921 single base substitution G A downstream_gene_variant KIRC-US 10 60124536 60124536 single base substitution T A exon_variant KIRC-US 10 60124536 60124536 single base substitution T A synonymous_variant A68A 204T>A KIRC-US 10 60124536 60124536 single base substitution T A upstream_gene_variant KIRC-US 10 60128479 60128479 single base substitution G T exon_variant KIRC-US 10 60128479 60128479 single base substitution G T splice_acceptor_variant KIRC-US 10 60128517 60128517 single base substitution G C exon_variant KIRC-US 10 60128517 60128517 single base substitution G C missense_variant A146P 436G>C LAML-KR 10 60121266 60121266 single base substitution C A missense_variant Q34K 100C>A LAML-KR 10 60121266 60121266 single base substitution C A upstream_gene_variant LICA-CN 10 60128520 60128520 single base substitution A T exon_variant LICA-CN 10 60128520 60128520 single base substitution A T missense_variant M147L 439A>T LICA-FR 10 60105771 60105772 deletion of <=200bp TT - intron_variant LICA-FR 10 60121556 60121556 deletion of <=200bp T - intron_variant LICA-FR 10 60121556 60121556 deletion of <=200bp T - upstream_gene_variant LICA-FR 10 60121649 60121649 single base substitution A T intron_variant LICA-FR 10 60121649 60121649 single base substitution A T upstream_gene_variant LICA-FR 10 60128300 60128300 insertion of <=200bp - A exon_variant LICA-FR 10 60128300 60128300 insertion of <=200bp - A intron_variant LINC-JP 10 60091844 60091845 deletion of <=200bp TT - upstream_gene_variant LINC-JP 10 60102219 60102219 single base substitution C G intron_variant LINC-JP 10 60109639 60109639 single base substitution A G intron_variant LINC-JP 10 60110928 60110928 single base substitution A G intron_variant LINC-JP 10 60120818 60120818 single base substitution A G intron_variant LINC-JP 10 60120818 60120818 single base substitution A G upstream_gene_variant LINC-JP 10 60121600 60121600 single base substitution A G intron_variant LINC-JP 10 60121600 60121600 single base substitution A G upstream_gene_variant LINC-JP 10 60128478 60128478 single base substitution A G exon_variant LINC-JP 10 60128478 60128478 single base substitution A G splice_acceptor_variant LINC-JP 10 60128754 60128754 single base substitution T C 3_prime_UTR_variant LINC-JP 10 60128754 60128754 single base substitution T C exon_variant LINC-JP 10 60131101 60131101 single base substitution T G downstream_gene_variant LIRI-JP 10 60089986 60089986 single base substitution A G upstream_gene_variant LIRI-JP 10 60090869 60090869 single base substitution C T upstream_gene_variant LIRI-JP 10 60094668 60094668 single base substitution C A upstream_gene_variant LIRI-JP 10 60094669 60094669 single base substitution C T upstream_gene_variant LIRI-JP 10 60097036 60097036 single base substitution C A intron_variant LIRI-JP 10 60098994 60098994 single base substitution T C intron_variant LIRI-JP 10 60100543 60100543 single base substitution A T intron_variant LIRI-JP 10 60101992 60101992 single base substitution C G intron_variant LIRI-JP 10 60102813 60102813 single base substitution A C intron_variant LIRI-JP 10 60103170 60103170 single base substitution T C intron_variant LIRI-JP 10 60103876 60103876 single base substitution G A intron_variant LIRI-JP 10 60105583 60105583 single base substitution A T intron_variant LIRI-JP 10 60105618 60105618 single base substitution A G intron_variant LIRI-JP 10 60107086 60107086 single base substitution A G intron_variant LIRI-JP 10 60107490 60107490 single base substitution C G intron_variant LIRI-JP 10 60107552 60107552 single base substitution C A intron_variant LIRI-JP 10 60108917 60108917 single base substitution A G intron_variant LIRI-JP 10 60109760 60109760 single base substitution A G intron_variant LIRI-JP 10 60110280 60110280 single base substitution T C intron_variant LIRI-JP 10 60110433 60110433 single base substitution C G intron_variant LIRI-JP 10 60113537 60113582 deletion of <=200bp TACTTTTTACCGTATGCAATCTGCATATCTATATAAAAGAATAATT - intron_variant LIRI-JP 10 60115839 60115839 single base substitution A G intron_variant LIRI-JP 10 60117084 60117084 single base substitution C T intron_variant LIRI-JP 10 60117446 60117446 single base substitution C T intron_variant LIRI-JP 10 60119508 60119508 single base substitution A G intron_variant LIRI-JP 10 60119508 60119508 single base substitution A G upstream_gene_variant LIRI-JP 10 60119677 60119677 single base substitution A G intron_variant LIRI-JP 10 60119677 60119677 single base substitution A G upstream_gene_variant LIRI-JP 10 60119704 60119704 single base substitution C G intron_variant LIRI-JP 10 60119704 60119704 single base substitution C G upstream_gene_variant LIRI-JP 10 60122889 60122889 single base substitution T G intron_variant LIRI-JP 10 60122889 60122889 single base substitution T G upstream_gene_variant LIRI-JP 10 60125467 60125467 single base substitution G T intron_variant LIRI-JP 10 60125467 60125467 single base substitution G T upstream_gene_variant LIRI-JP 10 60129487 60129487 single base substitution A T 3_prime_UTR_variant LIRI-JP 10 60129487 60129487 single base substitution A T downstream_gene_variant LIRI-JP 10 60130652 60130652 single base substitution T C downstream_gene_variant LIRI-JP 10 60132167 60132167 single base substitution C T downstream_gene_variant LIRI-JP 10 60132408 60132408 single base substitution A G downstream_gene_variant LIRI-JP 10 60133736 60133736 single base substitution A G downstream_gene_variant LUSC-KR 10 60095240 60095240 single base substitution G A intron_variant LUSC-KR 10 60097648 60097648 single base substitution C T intron_variant LUSC-KR 10 60101908 60101908 single base substitution C T intron_variant LUSC-KR 10 60107229 60107229 single base substitution C T intron_variant LUSC-KR 10 60112687 60112687 single base substitution C G intron_variant LUSC-KR 10 60115831 60115831 single base substitution A T intron_variant LUSC-KR 10 60116132 60116132 single base substitution T C intron_variant LUSC-KR 10 60117629 60117629 single base substitution C T intron_variant LUSC-KR 10 60119670 60119670 single base substitution C T intron_variant LUSC-KR 10 60119670 60119670 single base substitution C T upstream_gene_variant LUSC-KR 10 60123967 60123967 single base substitution G C intron_variant LUSC-KR 10 60123967 60123967 single base substitution G C upstream_gene_variant LUSC-KR 10 60127427 60127427 single base substitution A T intron_variant LUSC-KR 10 60127427 60127427 single base substitution A T upstream_gene_variant LUSC-KR 10 60130158 60130158 single base substitution A T 3_prime_UTR_variant LUSC-KR 10 60130158 60130158 single base substitution A T downstream_gene_variant LUSC-KR 10 60132029 60132029 single base substitution A G downstream_gene_variant LUSC-KR 10 60135372 60135372 single base substitution C A downstream_gene_variant LUSC-US 10 60124635 60124635 single base substitution A T missense_variant K101N 303A>T LUSC-US 10 60124635 60124635 single base substitution A T splice_region_variant LUSC-US 10 60124635 60124635 single base substitution A T upstream_gene_variant MALY-DE 10 60090395 60090395 single base substitution C A upstream_gene_variant MALY-DE 10 60090443 60090443 single base substitution G A upstream_gene_variant MALY-DE 10 60092450 60092450 single base substitution T C upstream_gene_variant MALY-DE 10 60094801 60094801 single base substitution G T 5_prime_UTR_variant MALY-DE 10 60096652 60096652 single base substitution T G intron_variant MALY-DE 10 60103024 60103024 insertion of <=200bp - T intron_variant MALY-DE 10 60110836 60110836 single base substitution C T intron_variant MALY-DE 10 60113548 60113548 single base substitution G A intron_variant MALY-DE 10 60113575 60113575 single base substitution G A intron_variant MALY-DE 10 60113880 60113880 single base substitution T A intron_variant MALY-DE 10 60124108 60124108 single base substitution C T intron_variant MALY-DE 10 60124108 60124108 single base substitution C T upstream_gene_variant MALY-DE 10 60125347 60125347 single base substitution G A intron_variant MALY-DE 10 60125347 60125347 single base substitution G A upstream_gene_variant MALY-DE 10 60133123 60133123 single base substitution G T downstream_gene_variant MALY-DE 10 60134088 60134088 insertion of <=200bp - T downstream_gene_variant MELA-AU 10 60090516 60090516 single base substitution C T upstream_gene_variant MELA-AU 10 60090662 60090662 single base substitution C T upstream_gene_variant MELA-AU 10 60090752 60090752 single base substitution C T upstream_gene_variant MELA-AU 10 60090756 60090756 single base substitution C T upstream_gene_variant MELA-AU 10 60090992 60090992 single base substitution C T upstream_gene_variant MELA-AU 10 60091162 60091162 single base substitution C T upstream_gene_variant MELA-AU 10 60091203 60091203 single base substitution C T upstream_gene_variant MELA-AU 10 60091480 60091480 single base substitution C T upstream_gene_variant MELA-AU 10 60091562 60091562 single base substitution G A upstream_gene_variant MELA-AU 10 60092288 60092288 single base substitution C T upstream_gene_variant MELA-AU 10 60092366 60092366 single base substitution G A upstream_gene_variant MELA-AU 10 60092588 60092588 single base substitution G A upstream_gene_variant MELA-AU 10 60092668 60092668 single base substitution G A upstream_gene_variant MELA-AU 10 60093012 60093012 single base substitution A G upstream_gene_variant MELA-AU 10 60093510 60093510 single base substitution G A upstream_gene_variant MELA-AU 10 60093813 60093813 single base substitution C T upstream_gene_variant MELA-AU 10 60094130 60094130 single base substitution G A upstream_gene_variant MELA-AU 10 60094283 60094283 single base substitution C T upstream_gene_variant MELA-AU 10 60095234 60095234 single base substitution C T intron_variant MELA-AU 10 60095385 60095385 single base substitution T C intron_variant MELA-AU 10 60096087 60096087 single base substitution G T intron_variant MELA-AU 10 60096642 60096642 single base substitution G A intron_variant MELA-AU 10 60096982 60096983 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 10 60097117 60097117 single base substitution C T intron_variant MELA-AU 10 60097146 60097146 single base substitution C T intron_variant MELA-AU 10 60097496 60097496 single base substitution C T intron_variant MELA-AU 10 60099244 60099244 single base substitution C T intron_variant MELA-AU 10 60099527 60099527 single base substitution T G intron_variant MELA-AU 10 60100199 60100199 single base substitution T C intron_variant MELA-AU 10 60100592 60100592 single base substitution T C intron_variant MELA-AU 10 60101441 60101441 single base substitution C T intron_variant MELA-AU 10 60101780 60101780 single base substitution T A intron_variant MELA-AU 10 60101986 60101986 single base substitution C T intron_variant MELA-AU 10 60102296 60102296 single base substitution G C intron_variant MELA-AU 10 60102714 60102714 single base substitution C T intron_variant MELA-AU 10 60103690 60103690 single base substitution C T intron_variant MELA-AU 10 60105501 60105501 single base substitution G T intron_variant MELA-AU 10 60105661 60105661 single base substitution C T intron_variant MELA-AU 10 60105671 60105671 single base substitution C T intron_variant MELA-AU 10 60106108 60106108 single base substitution C T intron_variant MELA-AU 10 60106723 60106723 single base substitution C T intron_variant MELA-AU 10 60107054 60107054 single base substitution T G intron_variant MELA-AU 10 60107226 60107226 single base substitution A T intron_variant MELA-AU 10 60107566 60107566 single base substitution C T intron_variant MELA-AU 10 60107607 60107607 single base substitution C T intron_variant MELA-AU 10 60108088 60108088 single base substitution C T intron_variant MELA-AU 10 60108611 60108611 single base substitution C T intron_variant MELA-AU 10 60109394 60109394 single base substitution C T intron_variant MELA-AU 10 60110392 60110392 single base substitution C T intron_variant MELA-AU 10 60110427 60110427 single base substitution C T intron_variant MELA-AU 10 60111393 60111393 single base substitution C T intron_variant MELA-AU 10 60111859 60111859 single base substitution G A intron_variant MELA-AU 10 60112227 60112227 single base substitution C T intron_variant MELA-AU 10 60112255 60112255 single base substitution C T intron_variant MELA-AU 10 60113116 60113116 single base substitution C T intron_variant MELA-AU 10 60113466 60113466 single base substitution T G intron_variant MELA-AU 10 60114667 60114667 single base substitution C T intron_variant MELA-AU 10 60115196 60115196 single base substitution T C intron_variant MELA-AU 10 60116209 60116209 single base substitution C T intron_variant MELA-AU 10 60116577 60116577 single base substitution C T intron_variant MELA-AU 10 60116741 60116741 single base substitution C T intron_variant MELA-AU 10 60117361 60117361 single base substitution T G intron_variant MELA-AU 10 60117715 60117715 single base substitution C T intron_variant MELA-AU 10 60118410 60118410 single base substitution C T intron_variant MELA-AU 10 60118923 60118923 single base substitution C T intron_variant MELA-AU 10 60119149 60119149 single base substitution C T intron_variant MELA-AU 10 60119229 60119229 single base substitution C T intron_variant MELA-AU 10 60119229 60119229 single base substitution C T upstream_gene_variant MELA-AU 10 60120719 60120719 single base substitution T A intron_variant MELA-AU 10 60120719 60120719 single base substitution T A upstream_gene_variant MELA-AU 10 60120878 60120878 single base substitution T A intron_variant MELA-AU 10 60120878 60120878 single base substitution T A upstream_gene_variant MELA-AU 10 60122253 60122253 single base substitution A T intron_variant MELA-AU 10 60122253 60122253 single base substitution A T upstream_gene_variant MELA-AU 10 60122269 60122270 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 10 60122269 60122270 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 10 60122349 60122349 single base substitution A G intron_variant MELA-AU 10 60122349 60122349 single base substitution A G upstream_gene_variant MELA-AU 10 60123029 60123029 single base substitution C T intron_variant MELA-AU 10 60123029 60123029 single base substitution C T upstream_gene_variant MELA-AU 10 60123926 60123926 single base substitution A T intron_variant MELA-AU 10 60123926 60123926 single base substitution A T upstream_gene_variant MELA-AU 10 60124860 60124860 single base substitution C T intron_variant MELA-AU 10 60124860 60124860 single base substitution C T upstream_gene_variant MELA-AU 10 60125574 60125574 single base substitution T A intron_variant MELA-AU 10 60125574 60125574 single base substitution T A upstream_gene_variant MELA-AU 10 60126839 60126839 single base substitution C T intron_variant MELA-AU 10 60126839 60126839 single base substitution C T upstream_gene_variant MELA-AU 10 60128542 60128542 single base substitution C T 3_prime_UTR_variant MELA-AU 10 60128542 60128542 single base substitution C T exon_variant MELA-AU 10 60129329 60129329 single base substitution C T 3_prime_UTR_variant MELA-AU 10 60129329 60129329 single base substitution C T downstream_gene_variant MELA-AU 10 60129329 60129329 single base substitution C T exon_variant MELA-AU 10 60129753 60129753 single base substitution A G 3_prime_UTR_variant MELA-AU 10 60129753 60129753 single base substitution A G downstream_gene_variant MELA-AU 10 60130156 60130156 single base substitution A T 3_prime_UTR_variant MELA-AU 10 60130156 60130156 single base substitution A T downstream_gene_variant MELA-AU 10 60130742 60130742 single base substitution C T downstream_gene_variant MELA-AU 10 60130786 60130786 single base substitution C T downstream_gene_variant MELA-AU 10 60131000 60131000 single base substitution C T downstream_gene_variant MELA-AU 10 60131250 60131250 single base substitution C T downstream_gene_variant MELA-AU 10 60132079 60132079 single base substitution T C downstream_gene_variant MELA-AU 10 60132107 60132107 single base substitution C T downstream_gene_variant MELA-AU 10 60132239 60132239 single base substitution G A downstream_gene_variant MELA-AU 10 60132273 60132273 single base substitution A T downstream_gene_variant MELA-AU 10 60132904 60132904 single base substitution C T downstream_gene_variant MELA-AU 10 60133194 60133194 single base substitution T G downstream_gene_variant MELA-AU 10 60133907 60133907 single base substitution C T downstream_gene_variant MELA-AU 10 60134545 60134545 single base substitution C T downstream_gene_variant MELA-AU 10 60134592 60134592 single base substitution C T downstream_gene_variant MELA-AU 10 60134900 60134900 single base substitution C T downstream_gene_variant MELA-AU 10 60135337 60135337 single base substitution C T downstream_gene_variant MELA-AU 10 60135471 60135471 single base substitution T A downstream_gene_variant MELA-AU 10 60135473 60135473 single base substitution C A downstream_gene_variant ORCA-IN 10 60112401 60112401 single base substitution A T intron_variant OV-AU 10 60091744 60091744 single base substitution G T upstream_gene_variant OV-AU 10 60093261 60093261 single base substitution A G upstream_gene_variant OV-AU 10 60103295 60103295 single base substitution A G intron_variant OV-AU 10 60103617 60103617 single base substitution G T intron_variant OV-AU 10 60103884 60103884 single base substitution C A intron_variant OV-AU 10 60108039 60108039 single base substitution G C intron_variant OV-AU 10 60108081 60108081 single base substitution A G intron_variant OV-AU 10 60108223 60108223 single base substitution G C intron_variant OV-AU 10 60108293 60108293 single base substitution G A intron_variant OV-AU 10 60118865 60118865 single base substitution C T intron_variant OV-AU 10 60123136 60123136 single base substitution C T intron_variant OV-AU 10 60123136 60123136 single base substitution C T upstream_gene_variant OV-AU 10 60127320 60127320 single base substitution G T intron_variant OV-AU 10 60127320 60127320 single base substitution G T upstream_gene_variant PACA-AU 10 60091002 60091002 single base substitution G A upstream_gene_variant PACA-AU 10 60093202 60093202 single base substitution G A upstream_gene_variant PACA-AU 10 60097113 60097113 single base substitution G C intron_variant PACA-AU 10 60122470 60122470 single base substitution A C intron_variant PACA-AU 10 60122470 60122470 single base substitution A C upstream_gene_variant PACA-AU 10 60125347 60125347 single base substitution G A intron_variant PACA-AU 10 60125347 60125347 single base substitution G A upstream_gene_variant PACA-AU 10 60133843 60133843 single base substitution T A downstream_gene_variant PACA-CA 10 60092476 60092476 single base substitution C T upstream_gene_variant PACA-CA 10 60093350 60093350 single base substitution G A upstream_gene_variant PACA-CA 10 60094109 60094109 single base substitution C T upstream_gene_variant PACA-CA 10 60095219 60095219 single base substitution C T intron_variant PACA-CA 10 60099104 60099104 single base substitution G A intron_variant PACA-CA 10 60102573 60102573 insertion of <=200bp - T intron_variant PACA-CA 10 60102594 60102594 single base substitution G T intron_variant PACA-CA 10 60104219 60104219 single base substitution C G intron_variant PACA-CA 10 60105019 60105019 single base substitution C T intron_variant PACA-CA 10 60105415 60105415 single base substitution A G intron_variant PACA-CA 10 60111660 60111660 single base substitution C G intron_variant PACA-CA 10 60111805 60111805 insertion of <=200bp - A intron_variant PACA-CA 10 60112831 60112831 single base substitution G T intron_variant PACA-CA 10 60118559 60118559 single base substitution C A intron_variant PACA-CA 10 60123371 60123371 single base substitution T C splice_region_variant PACA-CA 10 60123371 60123371 single base substitution T C upstream_gene_variant PACA-CA 10 60130631 60130631 single base substitution T G downstream_gene_variant PACA-CA 10 60131863 60131863 deletion of <=200bp T - downstream_gene_variant PACA-CA 10 60132888 60132888 deletion of <=200bp A - downstream_gene_variant PBCA-DE 10 60092918 60092918 deletion of <=200bp T - upstream_gene_variant PBCA-DE 10 60097614 60097614 deletion of <=200bp T - intron_variant PBCA-DE 10 60112352 60112352 insertion of <=200bp - A intron_variant PBCA-DE 10 60127063 60127064 deletion of <=200bp GT - intron_variant PBCA-DE 10 60127063 60127064 deletion of <=200bp GT - upstream_gene_variant PRAD-CA 10 60096846 60096846 single base substitution G A intron_variant PRAD-CA 10 60110680 60110680 single base substitution C T intron_variant PRAD-UK 10 60090869 60090869 single base substitution C T upstream_gene_variant PRAD-UK 10 60091958 60091958 single base substitution T A upstream_gene_variant PRAD-UK 10 60112060 60112060 single base substitution T A intron_variant PRAD-UK 10 60115558 60115558 single base substitution A G intron_variant PRAD-UK 10 60120349 60120349 single base substitution A G intron_variant PRAD-UK 10 60120349 60120349 single base substitution A G upstream_gene_variant PRAD-UK 10 60133359 60133359 single base substitution T G downstream_gene_variant RECA-EU 10 60090827 60090827 single base substitution C T upstream_gene_variant RECA-EU 10 60104997 60104997 single base substitution G A intron_variant RECA-EU 10 60108875 60108875 single base substitution C T intron_variant RECA-EU 10 60129259 60129259 single base substitution C T 3_prime_UTR_variant RECA-EU 10 60129259 60129259 single base substitution C T downstream_gene_variant RECA-EU 10 60129259 60129259 single base substitution C T exon_variant RECA-EU 10 60133997 60133997 single base substitution A G downstream_gene_variant SKCA-BR 10 60092205 60092205 single base substitution C T upstream_gene_variant SKCA-BR 10 60094054 60094054 single base substitution C T upstream_gene_variant SKCA-BR 10 60095914 60095914 single base substitution C T intron_variant SKCA-BR 10 60103689 60103689 single base substitution C T intron_variant SKCA-BR 10 60104627 60104627 single base substitution G T intron_variant SKCA-BR 10 60106390 60106390 single base substitution T G intron_variant SKCA-BR 10 60106407 60106407 single base substitution A G intron_variant SKCA-BR 10 60106844 60106844 single base substitution C T intron_variant SKCA-BR 10 60113779 60113779 single base substitution C A intron_variant SKCA-BR 10 60114955 60114955 single base substitution T C intron_variant SKCA-BR 10 60121620 60121620 single base substitution C T intron_variant SKCA-BR 10 60121620 60121620 single base substitution C T upstream_gene_variant SKCA-BR 10 60125533 60125533 single base substitution C T intron_variant SKCA-BR 10 60125533 60125533 single base substitution C T upstream_gene_variant SKCA-BR 10 60129531 60129531 single base substitution C T 3_prime_UTR_variant SKCA-BR 10 60129531 60129531 single base substitution C T downstream_gene_variant SKCA-BR 10 60129959 60129959 single base substitution T C 3_prime_UTR_variant SKCA-BR 10 60129959 60129959 single base substitution T C downstream_gene_variant SKCM-US 10 60123403 60123403 single base substitution T C missense_variant L52P 155T>C SKCM-US 10 60123403 60123403 single base substitution T C upstream_gene_variant SKCM-US 10 60124590 60124590 single base substitution C T exon_variant SKCM-US 10 60124590 60124590 single base substitution C T synonymous_variant L86L 258C>T SKCM-US 10 60124590 60124590 single base substitution C T upstream_gene_variant THCA-SA 10 60094951 60094951 single base substitution A G 5_prime_UTR_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand WSU-HN6 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + SJMB011 COSM255674 c.368T>C p.I123T Substitution - Missense 10:58367986-58367986 + UPCI:SCC090 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + TCGA-AN-A046-01 COSM3807383 c.383A>C p.K128T Substitution - Missense 10:58368001-58368001 + UM-SCC-11B COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + CS10 COSM4967459 c.396A>T p.E132D Substitution - Missense 10:58368014-58368014 + LOVO COSM2148146 c.171G>A p.P57P Substitution - coding silent 10:58363659-58363659 + PD3192a COSM1658778 c.397_398+2delAAGT p.? Unknown 10:58368015-58368018 + WSU-HN30 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + TCGA-EU-5906-01 COSM465784 c.204T>A p.A68A Substitution - coding silent 10:58364776-58364776 + CMLPh-001 COSM1234960 c.316A>G p.I106V Substitution - Missense 10:58367934-58367934 + BN17T COSM1603574 c.399-2A>G p.? Unknown 10:58368718-58368718 + BHY COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + PD14460a COSM5780486 c.207C>T p.F69F Substitution - coding silent 10:58364779-58364779 + 1874573 COSM1234960 c.316A>G p.I106V Substitution - Missense 10:58367934-58367934 + T3724 COSM4738668 c.130G>A p.A44T Substitution - Missense 10:58363618-58363618 + TCGA-CZ-5455-01 COSM3358792 c.436G>C p.A146P Substitution - Missense 10:58368757-58368757 + GBM_IV-39 COSM4738668 c.130G>A p.A44T Substitution - Missense 10:58363618-58363618 + TCGA-FS-A1ZZ-06 COSM3439090 c.258C>T p.L86L Substitution - coding silent 10:58364830-58364830 + S0004 COSM5881920 c.259G>A p.D87N Substitution - Missense 10:58364831-58364831 + PD13753a COSM5770506 c.25-3C>T p.? Unknown 10:58361335-58361335 + Pat_59_A COSM5837059 c.46G>A p.D16N Substitution - Missense 10:58361359-58361359 + WSU-HN8 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + TCGA-ER-A193-06 COSM3439089 c.155T>C p.L52P Substitution - Missense 10:58363643-58363643 + SCC-15 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + CN-AML-NR-05-Dx COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + BN17 COSM1603574 c.399-2A>G p.? Unknown 10:58368718-58368718 + 18T COSM110688 c.75delT p.V26fs*53 Deletion - Frameshift 10:58361388-58361388 + 18T COSM107966 c.73C>T p.P25S Substitution - Missense 10:58361386-58361386 + WA7 COSM242155 c.138A>C p.Q46H Substitution - Missense 10:58363626-58363626 + UM-SCC-4 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + UD-SCC-2 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + CN-AML-05-T COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + WSU-HN12 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + CAL33 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + HCC042T COSM5823763 c.439A>T p.M147L Substitution - Missense 10:58368760-58368760 + TCGA-33-4533-01 COSM684832 c.303A>T p.K101N Substitution - Missense 10:58364875-58364875 + UM-SCC-2 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + NOKSI COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + TCGA-CZ-5470-01 COSM465785 c.386C>A p.S129* Substitution - Nonsense 10:58368004-58368004 + CAL27 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + TCGA-CZ-5987-01 COSM465786 c.399-1G>T p.? Unknown 10:58368719-58368719 + 93VU147T COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + UM-SCC-47 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + SJMB011 COSM255674 c.368T>C p.I123T Substitution - Missense 10:58367986-58367986 + CS10 COSM4967458 c.394G>A p.E132K Substitution - Missense 10:58368012-58368012 + UM-SCC-17B COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + YUZEST COSM1702469 c.170C>T p.P57L Substitution - Missense 10:58363658-58363658 + SCC-25 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + WSU-HN13 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 + SCC-9 COSM4590600 c.100C>A p.Q34K Substitution - Missense 10:58361506-58361506 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.129683 10q21.1 602961

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A T Missense p.K101N c.303A>T 10 60124635 LUSC C T Missense p.P113S c.337C>T 10 60127715 CM C T Synonymous p.L86L c.258C>T 10 60124590 CM G C Missense p.A146P c.436G>C 10 60128517 RCCC G T 5-UTRSNV . c.1-161G>T 10 60094801 DLBCL G T SpliceAcceptorSNV . c.399-1G>T 10 60128479 RCCC T A Synonymous p.A68A c.204T>A 10 60124536 RCCC T C Missense p.L52P c.155T>C 10 60123403 CM T C Synonymous p.N81N c.243T>C 10 60124575 LUAD