PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ANKRD13A TMEM51 26186194 biogrid exp G G G G G P G G GP G GP G G G G G G G P G G G G GP G GP G ANKRD13A KCNIP2 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G ANKRD13A SMAD5 15231748 biogrid,i2d,mint,intact exp G G G G G G G G G G GP G GP G G G G G G G GP G G G G G G GP G UBE2N ANKRD13A 25260751 intact exp G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G GP G GP G ANKRD13A RNF11 15231748 biogrid,i2d,mint,intact exp G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G GP G GP G XPO1 ANKRD13A 26673895 biogrid exp G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G GP G GP G CTDSP2 ANKRD13A 26186194 biogrid exp G G G G GP G G G G G GP G GP G G G G G G G GP G G G G G G GP G ANKRD13A WBP1 26186194 biogrid exp P P P P P P P QDPR ANKRD13A 25416956 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMD4 ANKRD13A 26344197 biogrid exp G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G G G GP G LDLRAD4 ANKRD13A 26186194 biogrid exp G G G G GP G G GP G G GP G GP GP G G G G G G P G G G G GP G P G EGFR ANKRD13A 22298428,23956138 biogrid exp G G G G G G G G GP G G G G G G G G G GP G G G G G G GP G ANKRD13A ARRDC1 26186194 biogrid exp G G G G G G G GP G G GP G G G G G G G G G GP G G G G G G GP G ANKRD13A TOLLIP 21903422 innatedb,biogrid,intact exp G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G G G GP G SLAMF1 ANKRD13A 26186194 biogrid exp G G G GP G G G G P G GP G G G G G G G G G G G G G G G FAM189A2 ANKRD13A 26186194 biogrid exp G G G G GP G G GP G G GP G G GP G G G G G G GP G G G G GP G GP G ANKRD13A FBXO25 23940030 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ELAVL1 ANKRD13A 19322201 biogrid exp G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G G G GP G NTRK1 ANKRD13A 25921289 biogrid exp G P P P P ANKRD13A ERGIC3 26186194 biogrid exp G G G G GP G G G G G GP G GP GP G G G G G G GP G G G G GP G GP G UBE2V1 ANKRD13A 25260751 intact exp LAPTM5 ANKRD13A 15231748 hprd,biogrid,i2d,mint,intact exp G G G G GP G G GP G G GP G GP GP G G G G G G G G G G G GP G GP G UBA1 ANKRD13A 25260751 intact exp G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G GP G GP G FAM189B ANKRD13A 26186194 biogrid exp G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G G G GP G UBC ANKRD13A 22298428,16196087 biogrid exp, ortho G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G GP G GP G ANKRD28 ANKRD13A 23023127 pred G G G G G G G G G G G G GP G G G G G G G GP G G G G G G GP G DGKI ANKRD13A 23023127 pred G G G P G G G ANK1 ANKRD13A 23023127 pred G G GP G G G G P G G G G P ANKRD13A HECTD1 23023127 pred G G G G G G G GP G G GP G GP G G G G G G G GP G G G G G G GP G UBQLNL ANKRD13A 25402006 pred P P P P G P GP ANKRD13A AGAP4 23023127 pred G G G G GP G G GP G G GP G GP GP G G G G G G G G G G G G G GP G ANKRD13A SMURF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NEDD4 ANKRD13A 25402006 pred G G G GP G GP G GP G GP GP G G G G G G GP G G G G GP G P G ANKRD13A TANC2 23023127 pred G G G G GP G G GP G G GP GP P G G G G G GP G G G G GP G GP G NOTCH1 ANKRD13A 23023127 pred G G G G GP G G GP G G GP G GP GP G G G G G G GP G G G G GP G GP G RBPJ ANKRD13A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBC ANKRD13A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 16196087,20639865,21139048,21890473,21906983,21963094,21987572,22053931,22298428,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_268269|BIOGRID_264561|BIOGRID_173254|BIOGRID_181369|BIOGRID_225413|BIOGRID_160129|BIOGRID_259645|BIOGRID_222187|BIOGRID_143160|BIOGRID_162809|BIOGRID_172276 bait|bait|bait|bait|bait|bait|prey|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|prey ANKRD13A TOLLIP MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155820|UniProt_172494|UniProt_115752 prey|prey|prey bait|bait|bait EGFR ANKRD13A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22298428,23956138 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_285028|BIOGRID_259640 bait|bait prey|prey ANKRD13A SMAD5 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact) MINT_32332|MINT_61180|BIOGRID_259342|UniProt_78854 prey|prey|prey|prey bait|bait|bait|bait ANKRD13A RNF11 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0471(mint) BIOGRID_259428|MINT_60218|UniProt_78542|MINT_31453 prey|prey|prey|prey bait|bait|bait|bait LAPTM5 ANKRD13A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|(intact)|MI:0471(mint)|MI:0471(mint)|(biogrid) MINT_32665|MINT_32664|HPRD_2801|UniProt_79179|MINT_61512|MINT_61513|BIOGRID_259135 bait|bait|-|bait|bait|bait|bait prey|prey|-|prey|prey|prey|prey ANKRD13A FBXO25 MI:0004(affinity chromatography technology) 23940030 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_284561 prey bait ELAVL1 ANKRD13A MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_186543 bait prey

PPI - HINT Gene A Gene B PMID Method Quality UBA1 ANKRD13A 25260751 0997 LC UBE2N ANKRD13A 25260751 0997 LC UBE2V1 ANKRD13A 25260751 0997 LC LAPTM5 ANKRD13A 15231748 0018 HT ANKRD13A SMAD5 15231748 0018 HT ANKRD13A RNF11 15231748 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8IZ07 O14980 ANKRD13A XPO1 0.126 26673895 Q8IZ07 O15165 ANKRD13A LDLRAD4 0.126 26186194 Q8IZ07 P0CG48 ANKRD13A UBC 0.396 16196087,22298428 Q8IZ07 P22314 ANKRD13A UBA1 0.033 25260751 Q8IZ07 P55072 ANKRD13A VCP 0.569 26797118 Q8IZ07 P61088 ANKRD13A UBE2N 0.033 25260751 Q8IZ07 Q13404 ANKRD13A UBE2V1 0.033 25260751 Q8IZ07 Q7ARD3 ANKRD13A Q7ARD3 0.126 20711500 Q9Y3C5 Q8IZ07 RNF11 ANKRD13A 0.332 15231748 Q8N5I2 Q8IZ07 ARRDC1 ANKRD13A 0.126 26186194 Q9HCE7 Q8IZ07 SMURF1 ANKRD13A 0.183 20804422 Q9NS61 Q8IZ07 KCNIP2 ANKRD13A 0.126 26186194 Q9NW97 Q8IZ07 TMEM51 ANKRD13A 0.126 26186194 Q8TCJ0 Q8IZ07 FBXO25 ANKRD13A 0.183 23940030 Q9Y282 Q8IZ07 ERGIC3 ANKRD13A 0.126 26186194 Q8IZ07 P0C739 ANKRD13A P0C739 0.126 22810586 Q8IZ07 P0CK58 ANKRD13A P0CK58 0.126 22810586 Q8IZ07 Q6P5F9 ANKRD13A XPO1 0.126 26673895 Q8IZ07 Q8AZJ3 ANKRD13A Q8AZJ3 0.126 22810586 Q8IZ07 P12520 ANKRD13A VPR 0.126 22190034 Q8IZ07 P09417 ANKRD13A QDPR 0.183 25416956 Q8IZ07 P03246 ANKRD13A P03246 0.126 22810586 Q8IZ07 P13285 ANKRD13A LMP2 0.126 22810586 Q8IZ07 P04629 ANKRD13A NTRK1 0.126 25921289 Q8IZ07 P06463 ANKRD13A E6 0.126 22810586 Q8IZ07 P00533 ANKRD13A EGFR 0.309 23956138,22298428 Q99717 Q8IZ07 SMAD5 ANKRD13A 0.332 15231748 Q9H0E2 Q8IZ07 TOLLIP ANKRD13A 0.236 21903422 Q96G27 Q8IZ07 WBP1 ANKRD13A 0.126 26186194 Q8IZ07 P27105 ANKRD13A STOM 0.126 unassigned1312 Q8IZ07 Q13571 ANKRD13A LAPTM5 0.332 15231748 Q8IZ07 P81408 ANKRD13A FAM189B 0.126 26186194 Q8IZ07 Q13291 ANKRD13A SLAMF1 0.126 26186194 Q8IZ07 Q15717 ANKRD13A ELAVL1 0.126 19322201 Q8IZ07 P52565 ANKRD13A ARHGDIA 0.126 unassigned1312 Q8IZ07 Q15884 ANKRD13A FAM189A2 0.126 26186194 Q8IZ07 Q03135 ANKRD13A CAV1 0.376 26797118 Q8IZ07 Q2MG95 ANKRD13A BVLF1 {ECO:0000313|EMBL:CAJ75461.1} 0.126 22810586 Q8IZ07 P55036 ANKRD13A PSMD4 0.081 26344197 Q8IZ07 O14595 ANKRD13A CTDSP2 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CTDSP2 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database XPO1 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database LDLRAD4 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database EGFR ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database QDPR ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database UBC ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database UBA1 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database VCP ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database UBE2N ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database FAM189B ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database CAV1 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database SLAMF1 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database UBE2V1 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database LAPTM5 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database FAM189A2 ANKRD13A MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A ARRDC1 MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A FBXO25 MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A WBP1 MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A SMAD5 MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A TOLLIP MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A KCNIP2 MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A TMEM51 MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A ERGIC3 MI:0045 experimental interaction detection MI:0461 interaction database ANKRD13A RNF11 MI:0045 experimental interaction detection MI:0461 interaction database