PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SMN1, SMN2 JADE1 21900206 biogrid,mint,intact exp P P P P P P P P P P P P P P P P P P PFDN1 JADE1 21900206 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 CCDC94 25416956 biogrid,intact exp GP P P P GP G P GP GP GP G GP P G P GP GP GP GP G GP GP PKD1 JADE1 23001567 biogrid exp P P P P P P P P P P P P P P TMPO JADE1 26496610 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TK1 JADE1 21900206 biogrid,mint,intact exp GP GP G G P G G GP G GP GP GP GP P G G G GP G G GP GP G SUPT5H JADE1 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TMPO JADE1 26496610 intact exp JADE1 HIST2H3A, HIST2H3C, HIST2H3D 19187766 biogrid exp P P P P P P P P P P P P P P P P P P P JADE1 KAT5 15502158 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G AKT1 JADE1 23824745 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G HMOX2 JADE1 21900206 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G UBE2H JADE1 18806787 biogrid exp GP GP G G G GP G GP G G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G NPHP4 JADE1 22654112 biogrid exp GP G G G G GP G P G G GP G GP G G G GP G G G G GP G G G G G JADE1 SEPT8 21900206 biogrid,mint,intact exp G P G GP G GP G P P P P GP GP P GP P G GP P GP P JADE1 ING5 16387653,22144582,19187766, 25402006, 23023127 biogrid exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G JADE1 MEAF6 22144582,19187766, 25402006, 23023127, 21836163 biogrid exp, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 ING4 16387653,22144582,26496610, 25402006, 23023127, 21836163 biogrid,intact exp, pred GP GP G G G GP G GP G G GP GP GP GP G GP GP G P G GP GP GP G GP GP GP GP G VHL JADE1 25416956,12169691,14973063, 21836163 hprd,biogrid,i2d,intact exp, pred G G G G G G G G G G GP GP GP G G G G G P G G GP GP G G G G GP G KAT7 JADE1 16387653,22144582,26186194,19187766,18684714,24739512, 25402006, 21836163 biogrid exp, pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G GP G GP G GP GP G CTNNB1 JADE1 18806787, 25402006 biogrid exp, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G UBE3A JADE1 21900206,24722188,16713569, 21836163 hprd,biogrid,mint,intact exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G UBE2E1 JADE1 18806787, 23023127 biogrid exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G G GP G GP GP G HOXC12 JADE1 ortho G G HOXA9 JADE1 ortho P P P P P P P P P P P P P P P P P P P TCF3 JADE1 ortho GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G POU5F1 JADE1 ortho P P P P P P P P P P P P P P P P P P P PAX8 JADE1 ortho G GP G G G G G G GP G GP G GP G G GP G G G G G G G G GP G G G G JADE1 CREBBP 25402006 ortho, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 TRRAP 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 HDAC7 25402006 pred G G G G G GP G GP GP G GP G G GP G G GP G G G GP G G G G GP GP GP G JADE1 CARD9 25402006 pred G G P P P G P P GP P P JADE1 BARD1 25402006 pred P G G P P GP P P P GP G GP P G P P GP P G P GP GP GP G BRPF1 JADE1 25402006, 23023127 pred GP GP G G G GP G GP G G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 RUVBL1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP G GP GP G BRD1 JADE1 23023127 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G GP G ORC1 JADE1 25402006 pred P P G G P P P P P P P P P P P P P P P UBE2N JADE1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G CBX7 JADE1 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G CDK11B JADE1 25402006 pred JADE1 BRPF3 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G PCGF2 JADE1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JADE1 TSPYL2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP G GP GP GP GP G HNF1A JADE1 25402006 pred GP G G G G G G G GP G GP GP GP G G GP G G G GP G GP MAPK3 JADE1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G FOXO3 JADE1 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 SAP130 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMARCA5 JADE1 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 GLIS2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G BPTF JADE1 23023127 pred G GP G G G GP G G GP G GP GP GP G G GP GP G G G GP G GP G GP G GP GP G VBP1 JADE1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JUP JADE1 25402006 pred GP G G G G G G G GP G GP GP G G G GP G G GP G GP GP GP G GP G GP G G JADE1 HIF1AN 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 LEF1 25402006 pred G G G G G GP G GP G GP GP GP G G GP G G G G G G GP G G G JADE1 RUVBL2 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 USP33 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G HIF1A JADE1 25402006 pred GP GP G G G GP G G GP G GP G GP GP G GP GP G GP G GP G GP G GP GP GP GP G PDC JADE1 21836163 pred P P P P P P P P P P P P P P P NR4A1 JADE1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD7 JADE1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP P G SPTBN2 JADE1 23023127 pred GP GP G GP G G GP GP P P GP GP G GP GP P P P GP MBD3 JADE1 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G G G GP G G G GP GP GP GP G APBB1 JADE1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G G GP G GP G GP GP GP G G GP GP GP G JADE1 HUWE1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G ZNF197 JADE1 25402006 pred G GP G G G GP G GP GP G GP G GP GP G GP GP G GP G G G GP G GP G GP GP G MCM6 JADE1 25402006 pred GP GP G G G GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G ACVR1B JADE1 23023127 pred G G G G G GP G G GP G GP GP GP G G GP GP G GP G GP G G G GP G GP GP G DGKI JADE1 25402006 pred G G G P G G G JADE1 ING3 25402006 pred G G G G G G G G G G GP G GP GP G G G G G G GP GP G G G G GP GP G JADE1 RERG 23023127 pred G GP G GP G GP GP G GP G GP GP G GP GP G GP G G GP G GP G GP GP G JADE1 TCF7L2 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 RNF139 25402006 pred G GP G G G GP G G GP G GP GP GP G G GP GP G GP G GP GP G G GP G GP GP G JADE1 TCF7L1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JADE1 ASH1L 23023127 pred GP GP G G G GP G G GP G G G GP G G G GP G GP G GP GP GP G G G G GP G ACTL6A JADE1 25402006 pred GP GP G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G KMT2A JADE1 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 CHD5 23023127 pred P P G GP P P G P P P P P GP P G P P P P P P GP JADE1 EPAS1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G PRKCB JADE1 23023127 pred GP GP G G G GP G G GP G GP G GP GP G G GP G GP G G GP GP G G GP GP GP G HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 JADE1 25402006 pred P P P P P P P P P P P P P P P P P P P JADE1 KAT6B 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 KAT8 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JADE1 TAOK2 23023127 pred GP GP G G G GP G G GP G G GP GP G G GP GP G GP G GP G G G GP GP GP GP G JADE1 CBY1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JADE1 EGLN3 25402006 pred P P G G G GP G G G G G G G G G G G G G G G G AR JADE1 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G GP G JADE1 KAT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G JADE1 KIAA1377 25402006 pred GP GP G G G GP G G GP G GP P GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 JADE2 23023127 pred G GP G G G GP G G GP G G G G G G GP GP G G G GP GP G G GP G G G G CTCF JADE1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G JADE1 KAT6A 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TP53 JADE1 25402006 pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G EP300 JADE1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G KIAA1109 JADE1 25402006 pred GP G G G G G G GP GP G GP G GP G G GP G G GP G GP GP G G GP G GP GP G DCLK1 JADE1 23023127 pred G G G GP G G GP G GP G GP GP G GP G P G G G GP GP GP P G ULK1 JADE1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JADE1 EP400 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q6IE81 far western blotting 16387653 association C 7 Q6IE81 mass spectrometry studies of complexes 16387653 association C 4 Q6IE81 affinity chromatography technology 16387653 association C 4 Q6IE81 far western blotting 16387653 association C 11 Q9BW85 Q6IE81 two hybrid prey pooling approach 25416956 physical association X 2 Q9BW85 Q6IE81 two hybrid array 25416956 physical association X 2 Q9BW85 Q6IE81 validated two hybrid 25416956 physical association X 2 Q81X78 Q6IE81 two hybrid pooling approach 20711500 physical association X 2 A0A024R2F2 Q6IE81 mammalian protein protein interaction trap 25416956 physical association X 2 Q92599 Q6IE81 two hybrid 21900206 physical association X 2 P04183 Q6IE81 two hybrid 21900206 physical association X 2 Q6IE81 P30519 two hybrid 21900206 physical association X 2 Q6IE81 O60925 two hybrid 21900206 physical association X 2 Q16637 Q6IE81 two hybrid 21900206 physical association X 2 Q6IE81 Q05086 two hybrid array 16713569 physical association X 2 Q6IE81 Q05086 two hybrid 21900206 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B PHF17 KAT5 MI:0004(affinity chromatography technology) 15502158 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_118164 bait prey PHF17 SEPT8 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_156666|UniProt_180429|UniProt_159831 prey|prey|prey bait|bait|bait HMOX2 PHF17 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_158799|BIOGRID_156157|UniProt_179397 bait|bait|bait prey|prey|prey PHF17 HIST2H3A; MI:0004(affinity chromatography technology) 19187766 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_119066 bait prey CTNNB1 PHF17 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18806787 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_116424|BIOGRID_116423|BIOGRID_116422 prey|bait|prey bait|prey|bait TK1 PHF17 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_157341|UniProt_157549|UniProt_178147 bait|bait|bait prey|prey|prey VHL PHF17 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0493(in vivo) 12169691,14973063 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_77568|BIOGRID_121999|BIOGRID_121998|BIOGRID_103386|HPRD_4908 bait|bait|bait|prey|- prey|prey|prey|bait|- PHF17 MEAF6 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16387653,19187766,22144582 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_39513|BIOGRID_119065|BIOGRID_167177|BIOGRID_167175 -|bait|bait|prey -|prey|prey|bait UBC PHF17 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21890473,23001567 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_216982|BIOGRID_216981|BIOGRID_263336 prey|bait|bait bait|prey|prey PKD1 PHF17 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23001567 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_292042|BIOGRID_292041|BIOGRID_292040 bait|prey|bait prey|bait|prey PFDN1 PHF17 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_180054|UniProt_159456|BIOGRID_158630 bait|bait|bait prey|prey|prey KAT7 PHF17 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16387653,18684714,19187766,22144582 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) HPRD_39513|BIOGRID_119017|BIOGRID_119063|BIOGRID_167176|BIOGRID_167173|BIOGRID_118447 -|prey|prey|prey|bait|bait -|bait|bait|bait|prey|prey PHF17 ING5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16387653,19187766,22144582 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_118457|BIOGRID_119064|BIOGRID_167174 prey|bait|prey bait|prey|bait UBE3A PHF17 MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 16713569,21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact)|(intact)|MI:0471(mint)|MI:0468(hprd)|(intact)|(biogrid)|MI:0471(mint) BIOGRID_215406|UniProt_85909|UniProt_157779|MINT_83144|HPRD_26156|UniProt_178377|BIOGRID_156553|MINT_50856 bait|bait|bait|bait|-|bait|bait|bait prey|prey|prey|prey|-|prey|prey|prey PHF17 ING4 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16387653,22144582 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_39513|BIOGRID_167178|BIOGRID_118438 -|bait|prey -|prey|bait SMN1 PHF17 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_158071|UniProt_157324|UniProt_177922 bait|bait|bait prey|prey|prey AKT1 PHF17 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23824745 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_297196|BIOGRID_297195|BIOGRID_297194|BIOGRID_297193 bait|prey|prey|bait prey|bait|bait|prey

PPI - HINT Gene A Gene B PMID Method Quality SUPT5H JADE1 26496610,26496610 0007,0004 HT KAT7 JADE1 22144582,24739512,26186194,16387653,24739512,22144582,19187766,18684714 0096,0428,0004,0004,0004,0004,0004,0004 LC,HT VHL JADE1 12169691,12169691,14973063,12169691,12169691,14973063 0018,0019,0096,0045,0004,0004 LC TMPO JADE1 26496610 0007 HT Q59G12 JADE1 26496610 0004 HT JADE1 ING5 19187766,16387653,22144582 0004,0004,0004 LC JADE1 MEAF6 19187766,22144582,22144582 0004,0096,0004 LC JADE1 ING4 26496610,22144582,16387653,26496610 0007,0096,0004,0004 HT,LC SUPT5H JADE1 26496610,26496610 0007,0004 HT KAT7 JADE1 26186194 0004 HT TMPO JADE1 26496610 0007 HT Q59G12 JADE1 26496610 0004 HT JADE1 ING4 26496610,26496610 0007,0004 HT KAT7 JADE1 22144582,24739512,16387653,24739512,22144582,19187766,18684714 0096,0428,0004,0004,0004,0004,0004 LC VHL JADE1 12169691,12169691,14973063,12169691,12169691,14973063 0018,0019,0096,0045,0004,0004 LC JADE1 ING5 19187766,16387653,22144582 0004,0004,0004 LC JADE1 MEAF6 19187766,22144582,22144582 0004,0096,0004 LC JADE1 ING4 22144582,16387653 0096,0004 LC PFDN1 JADE1 21900206 0018 HT NPHP4 JADE1 22654112,22654112,22654112 0416,0007,0004 LC TK1 JADE1 21900206 0018 HT HMOX2 JADE1 21900206 0018 HT CTNNB1 JADE1 18806787,18806787 0004,0415 LC VHL JADE1 12169691,12169691,12169691,12169691,25416956 0018,0019,0045,0004,0231 LC,HT UBE3A JADE1 16713569,24722188,21900206,16713569 0397,0018,0018,0018 HT TCEB1 JADE1 12169691 0018 LC SMN1|SMN2 JADE1 21900206 0018 HT JADE1 SEPT8 21900206 0018 HT JADE1 CCDC94 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9HAF1 Q6IE81 MEAF6 JADE1 0.569 22144582,19187766 Q6IE81 O75161 JADE1 NPHP4 0.376 22654112 Q8WYH8 Q6IE81 ING5 JADE1 0.454 22144582,16387653,19187766 Q71DI3 Q6IE81 HIST2H3D JADE1 0.309 19187766 Q6IE81 Q05086 JADE1 UBE3A 0.61 21900206,16713569,24722188 Q6IE81 P62256 JADE1 UBE2H 0.309 18806787 Q6IE81 P04183 JADE1 TK1 0.332 21900206 Q6IE81 P51965 JADE1 UBE2E1 0.309 18806787 Q6IE81 P40337 JADE1 VHL 0.74 25416956,14973063,12169691 Q92993 Q6IE81 KAT5 JADE1 0.21 15502158 Q9UNL4 Q6IE81 ING4 JADE1 0.539 22144582,26496610,16387653 Q81X78 Q6IE81 ENO JADE1 0.126 20711500 Q92599 Q6IE81 SEPT8 JADE1 0.332 21900206 Q6IE81 Q16637 JADE1 SMN2 0.332 21900206 Q9CSU0 Q6IE81 RPRD1B JADE1 0.236 26496610 Q6IE81 P83917 JADE1 CBX1 0.236 26496610 Q6IE81 P31749 JADE1 AKT1 0.623 23824745 Q9UQR1 Q6IE81 ZNF148 JADE1 0.236 unassigned1304 Q6IE81 O00267 JADE1 SUPT5H 0.236 26496610 Q6IE81 O60925 JADE1 PFDN1 0.332 21900206 Q6IE81 P42167 JADE1 TMPO 0.236 26496610 Q9BW85 Q6IE81 CCDC94 JADE1 0.583 25416956,unassigned1304 Q6IE81 O95251 JADE1 KAT7 0.858 22144582,24739512,19187766,16387653,18684714,26186194 Q6IE81 P30519 JADE1 HMOX2 0.332 21900206 Q6IE81 P35222 JADE1 CTNNB1 0.569 18806787 Q6IE81 P98161 JADE1 PKD1 0.376 23001567 Q6IE81 P42166 JADE1 TMPO 0.126 26496610

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SUPT5H JADE1 MI:0045 experimental interaction detection MI:0461 interaction database PFDN1 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database NPHP4 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database KAT7 JADE1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TK1 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database UBC JADE1 MI:0045 experimental interaction detection MI:0461 interaction database TCF3 JADE1 MI:0362 inference MI:0461 interaction database HOXD9 JADE1 MI:0362 inference MI:0461 interaction database HMOX2 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database HOXA9 JADE1 MI:0362 inference MI:0461 interaction database HOXC12 JADE1 MI:0362 inference MI:0461 interaction database AKT1 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database CTNNB1 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database VHL JADE1 MI:0045 experimental interaction detection MI:0461 interaction database TMPO JADE1 MI:0045 experimental interaction detection MI:0461 interaction database TMPO JADE1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E1 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2H JADE1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H3A JADE1 MI:0362 inference MI:1106 pathways database CBX1 JADE1 MI:0362 inference MI:0461 interaction database PKD1 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database POU5F1 JADE1 MI:0362 inference MI:0461 interaction database UBE3A JADE1 MI:0045 experimental interaction detection MI:0461 interaction database POU5F1B JADE1 MI:0362 inference MI:0461 interaction database PAX8 JADE1 MI:0362 inference MI:0461 interaction database SMN1 JADE1 MI:0045 experimental interaction detection MI:0461 interaction database JADE1 HIST2H3A MI:0045 experimental interaction detection MI:0461 interaction database JADE1 ING5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database JADE1 SEPT8 MI:0045 experimental interaction detection MI:0461 interaction database JADE1 CREBBP MI:0362 inference MI:0461 interaction database JADE1 KAT5 MI:0045 experimental interaction detection MI:0461 interaction database JADE1 CCDC94 MI:0045 experimental interaction detection MI:0461 interaction database JADE1 MEAF6 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database JADE1 RPRD1B MI:0362 inference MI:0461 interaction database JADE1 ING4 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database