PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRAF5 NGFRAP1 10514511 hprd exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 THAP1 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G TRAF5 NMI 25416956,21516116 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 RAD23A 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TRIM27 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 SEC13 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G G G G G G GP GP G GP G GP GP GP G GP GP GP G G TRAF5 TRAF5 9718306,25416956,22493164,9153189,15383523,9162022 innatedb,hprd,biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 SERPINB9 25416956 biogrid,intact exp GP GP G G GP G G G G G GP G G GP G G G G G G G G G G G GP G GP G TRAF5 HOMER1 26186194 biogrid exp G G GP G GP G G G G G GP G G G G G G G G G G G TRAF5 DGKH 21988832 biogrid,intact exp P P G P GP G GP P G P GP P P GP GP G P GP P P GP GP P P P G TRAF5 ELAVL1 23772036 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TRAF5 RNF111 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 COG7 21903422 innatedb,biogrid exp GP GP G G GP GP G G GP G GP GP GP G G GP GP G GP G G GP GP G GP G GP GP G TRAF5 ENOX2 25416956 biogrid,intact exp G G G G GP GP G G GP G GP G GP GP G G GP G G G GP G G G G GP GP G TRAF5 TNFRSF17 20676093 innatedb,biogrid,intact,bci exp P P G GP P P GP P P P GP GP P P P P GP P GP GP GP P TRAF5 LZTS2 26186194 biogrid exp GP GP G G G GP G G GP G GP GP G G G GP GP G GP G GP GP GP G GP G GP GP G TRAF5 COMMD3 21988832 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 NFATC2IP 11435475 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 TRIM8 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 SDCBP 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 MDM2 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 NUMBL 21988832,22593207 biogrid,intact exp G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G G GP G TRAF5 UBE2O 23381138 biogrid exp G GP G G GP GP G GP G GP G G G G GP G G G G G G G GP G TRAF5 IL6ST 24681564 innatedb exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 COG5 21903422 innatedb,biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 RIPK4 12446564 innatedb exp G P P P GP G GP GP GP P G G P GP G GP GP G G G P GP GP TRAF5 ZFAND6 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 CCDC184 25416956 biogrid,intact exp P GP G P GP G P GP G P P P P P GP P G P P GP P P P P GP G TRAF5 CAPNS1 21988832 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 MAP3K11 19918265 innatedb exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 GORASP2 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 USP25 23042150 intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 SRSF1 21822258 biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TNFRSF11A 9685412,10025951,9852070,9774460,10075662, 25402006, 21836163 innatedb,hprd,biogrid,i2d,intact exp, ortho, pred GP P G GP P P GP P P GP G GP P P G P G G P GP GP P G TRAF5 TNFRSF13B 20676093,10880535, 25402006 innatedb,hprd,biogrid,intact,bci exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 MAVS 20161788, 25402006 innatedb,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 LTBR 9511754,9162022,14517219,8663299, 25402006, 21836163 innatedb,hprd,biogrid,bci exp, ortho, pred GP G G GP P G G G GP G GP GP G GP P G G G GP G GP G GP GP GP GP G TRAF5 TRAF3IP2 21822258,12089335, 25402006, 21836163 hprd,biogrid,intact,bci exp, ortho, pred GP GP P P G P GP GP GP GP GP G GP P G GP G GP GP GP P GP GP GP P G TRAF5 TNFRSF14 9153189,9162022, 25402006, 21836163 hprd,biogrid,intact,bci exp, ortho, pred GP GP G G GP G G GP GP G GP GP GP GP G GP G G GP G G GP GP G GP GP GP GP G TRAF5 MAP3K7 17384642, 25402006 innatedb,biogrid exp, pred GP GP G G G GP G G GP G G GP GP G G G GP G GP G GP GP G G G G GP GP G TRAF5 TRAF2 9718306,21903422, 25402006, 23023127, 21836163 innatedb,biogrid,bci exp, pred P P P P P P P P P P P P P P P P P P GP GP P TRAF5 TRIM37 11279055, 25402006 hprd,biogrid,bci exp, pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G GP GP GP G GP G GP GP G TRAF5 TICAM1 14982987, 25402006 biogrid exp, pred GP GP G P G GP GP GP GP GP GP G GP P G GP GP GP GP GP GP GP GP P G TRAF5 SPOP 25402006 bci exp, pred G GP G G G GP G G GP G GP GP GP G G G GP G GP G GP GP GP G G G GP GP G TRAF5 MAP3K5 9774977,10523862, 25402006, 21836163 hprd,biogrid,bci exp, pred G GP G G GP GP G G GP G GP G GP GP G G GP G GP G G GP G G G GP GP GP G TRAF5 TNFRSF9 15941918, 25402006, 16082366 innatedb,biogrid exp, pred GP G G G GP G GP GP P G P G GP G GP G P GP GP GP GP G TRAF5 CD27 9582383, 25402006, 21836163 hprd,biogrid,bci exp, pred G G G GP G G G G G G GP G G G G G G G G G G GP G G TRAF5 TNFRSF8 11971184,8999898,9511754, 25402006, 21836163 innatedb,hprd,biogrid,bci exp, pred GP G G G G G G G GP G G G G GP G G G G G G G G G G GP G G TRAF5 TRAIP 17544371, 25402006 biogrid exp, pred P P P P P P P P P P P P P P P P P P P P GP TRAF5 TRADD 25402006 bci exp, pred GP GP G G GP GP G G GP G GP G GP GP G G GP G G G GP GP GP G G GP GP GP G TRAF5 LTA 25402006 bci exp, pred P P P P P P P P P P P P P P P P P P P TRAF5 RIPK1 11479302, 25402006, 21836163 hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TDP2 10764746, 25402006, 21836163 hprd,biogrid,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 USP7 11279055, 25402006 hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 NUP62 25402006 bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G TRAF5 TNFRSF12A 12529173, 16082366 hprd exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP GP GP GP G P GP GP G TRAF5 TNFRSF4 9488716,15941918, 25402006, 21836163 innatedb,hprd,biogrid,bci exp, pred P GP GP G TRAF5 NGFR 10514511, 25402006, 16082366 biogrid exp, pred GP G G P P G G G G G G P G G G TRAF5 TRAF3 21903422,9718306,25241761,20161788,15383523, 25402006, 21836163 innatedb,hprd,biogrid,intact,bci exp, pred G GP G G GP GP G G G G GP GP GP GP G GP GP G GP G GP G GP G GP G GP GP G TRAF5 CAMLG 20676093, 25402006 innatedb,intact exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 TNFRSF19 10809768, 25402006, 21836163, 16082366 hprd,intact exp, pred GP GP G G P G GP GP G GP P GP GP G GP GP G GP G P GP GP GP GP GP GP GP G TRAF5 RIPK2 9642260, 25402006 hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G G GP G TRAF5 EIF2AK2 15121867, 25402006 biogrid exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G TRAF5 TNFRSF1B 25402006, 16082366 bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP GP GP GP GP GP GP GP P G TRAF5 TNFRSF1A 25402006, 23023127, 16082366 bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TRAF6 9718306,25416956,22493164,21516116, 25402006, 23023127, 21836163 innatedb,biogrid,mint,intact,bci exp, pred GP GP G G GP G G GP GP G GP GP GP G G GP G G G G GP GP GP G GP GP GP GP G TRAF5 CD40 9718306,20614026,9511754,8790348,11562359,21041727,12220533,17332487,9990007,20676093, 25402006, 21836163 innatedb,hprd,biogrid,intact,bci exp, pred G G G G G G G G G G G G G GP G G G G G G G G G G G GP G G G TRAF5 ZMYND11 20138174, 25402006 biogrid,mint,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 MAP3K14 9275204, 25402006, 21836163 hprd,biogrid,i2d,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 IL4R 25402006 pred GP GP G G GP P G GP GP G GP G GP GP G GP GP G GP GP G GP P GP GP GP GP G TRAF5 XIAP 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP G GP G GP GP G TRAF5 REL 25402006 pred GP G G G GP GP G G GP G GP G GP GP G GP GP G GP G P GP GP G GP GP GP GP G TRAF5 TUBB8 25402006 pred P P P P P P P P P P P P P P P P P P TRAF5 DAXX 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 CASP7 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G TRAF5 SOCS1 25402006 pred GP GP P P GP GP GP GP GP GP G GP P G GP G GP P GP P GP GP GP GP G TRAF5 MAP2K4 25402006 pred GP GP G G GP GP G G GP G GP G GP G G G GP G G G GP G G G G G GP GP G TRAF5 TRIM38 23023127 pred GP GP G GP P G GP GP GP GP GP GP G GP GP G GP GP GP GP GP GP GP GP P G TRAF5 TNFSF4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP P GP G P G P GP GP GP GP G GP GP G TRAF5 SQSTM1 25402006 pred GP GP G G GP G G G GP G GP GP GP GP G GP G G GP G GP GP GP GP GP GP GP GP G TRAF5 CASP14 25402006 pred G G G TRAF5 ATG10 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP P GP G GP G GP GP GP GP GP P P P G TRAF5 TGFB1 23023127 pred G G G G GP G G G G G G G G G G GP G G G G GP G G GP GP GP G G TRAF5 SPOPL 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G TRAF5 IL1RL1 25402006 pred P GP P P P GP P GP GP P P P GP P P P P P P P G TRAF5 TUBB3 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 CHUK 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TRAF4 25402006 pred G GP G GP G P GP G GP GP GP G G GP GP G GP G GP G GP P GP G GP GP G TRAF5 TNFAIP3 25402006, 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TRAF5 PPP5C 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TNFRSF21 25402006 pred G P G G G GP G G GP G G G GP G G GP GP G GP G G G G GP G G G TRAF5 IKBKG 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 TAB2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 TUBB1 25402006 pred GP P G GP P G GP P P P P P P P G P P P P GP P GP TRAF5 UBE2N 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 CYLD 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP TRAF5 TPD52L1 25402006 pred G GP G G GP GP G G GP G GP G G GP G GP GP G GP G GP GP GP G GP GP GP G G TRAF5 TNFRSF25 25402006, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G TRAF5 TNFSF14 25402006 pred GP P P P P P P GP GP G P P G P P P P P G P P TRAF5 TRAF3IP1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G P GP GP GP GP GP GP GP G TRAF5 JAK2 25402006 pred G GP G G GP GP G GP GP G GP P GP GP G P GP G P P G GP G GP GP GP GP TRAF5 MALT1 25402006, 23023127 pred G G GP G G G G G G GP G G G G G G G G G G G G GP G TRAF5 TUBA1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 RNF31 23023127 pred P P G G GP GP P P G GP GP GP P GP GP GP G GP P P GP GP GP P GP TRAF5 EDAR 21836163, 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 YWHAZ 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TUBA1A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G NFKBIE TRAF5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP GP GP GP GP GP GP GP GP G TRAF5 BIRC3 25402006 pred GP G GP G G GP P GP G GP G GP G GP P G GP GP GP GP GP TRAF5 MAP3K6 25402006 pred GP GP P P G GP GP GP P GP GP G GP P G GP P GP GP GP GP GP GP P G TRAF5 ARRB2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TRAF5 FADD 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G GP GP GP GP GP GP G TRAF5 MAP2K6 25402006 pred GP G G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP G G TRAF5 CARD9 21836163 pred G GP P P P G P P GP P P TRAF5 GSTM1 25402006 pred G GP G G G G G G G G G GP G G G G G G G G G G G G G G G GP G TRAF5 DIABLO 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 SRC 25402006 pred GP GP G GP GP G G GP G G G G GP GP G G G GP GP G GP GP GP GP G TRAF5 MAP3K8 21836163 pred GP GP G GP P G GP GP GP GP GP GP G P P G P GP GP P P GP GP GP P G TRAF5 RNF25 23023127 pred P G P P P P P P P P P P P P P GP P P TRAF5 YWHAQ 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 OTUD7B 25402006, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 RIPK3 25402006 pred GP P G GP P GP GP G P P GP GP G GP P GP G GP GP GP GP GP GP GP P TRAF5 IL6R 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 CASP8 25402006, 23023127 pred GP GP G GP P GP GP GP GP GP GP G GP P G P G GP GP GP P GP GP GP GP G TRAF5 AKT1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 MAP2K7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 TUBB 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TNFRSF11B TRAF5 16082366 pred P P P P P P GP GP P P P P P P P P P P P P P TRAF5 TRAF1 25402006 pred G G G G GP GP G G GP G GP G G GP G G GP G G G G G G G GP G G G TRAF5 ABL1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 FAS 16082366 pred GP GP G G G GP G G GP GP G GP GP G GP GP G GP G GP GP G G GP G GP GP G TRAF5 TNFSF15 25402006 pred GP GP G GP P G P GP GP P GP GP G GP GP P G GP G GP P GP P GP P TRAF5 TAB3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TNFSF13B 25402006 pred GP GP G G GP GP G GP GP G P GP GP GP G GP GP GP GP GP GP P GP GP GP P G TRAF5 LTB 25402006 pred GP G G G GP GP G GP GP G GP GP G GP GP GP G P G G G GP GP GP P TRAF5 YWHAH 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TNFRSF10C 16082366 pred P P G GP P P P P P P P P P P P P P P GP P P TRAF5 CASP3 25402006 pred GP G G G GP G G GP G G G GP GP G GP G G GP G GP G G G GP GP GP GP G TRAF5 SP100 23023127 pred GP GP G GP P G GP GP GP GP GP GP G GP P G P G GP GP GP GP GP GP GP P G TRAF5 NLRP4 21836163 pred P P P P P P P P P P P P P P P P P GP TRAF5 TMEM173 25402006 pred GP G G G GP GP G GP GP G G G GP GP G G GP G GP G GP GP GP G G GP GP GP G TRAF5 ELP2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 CFLAR 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 MAP3K3 25402006 pred G G G G GP GP G GP G G GP G GP GP G GP GP G G G GP G G G GP GP GP G G TRAF5 TNFRSF10B 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TUBA3C, TUBA3D 25402006 pred P P P P P P P P P P P P P TRAF5 TUBA1C 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 PRKCZ 25402006 pred G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP P GP GP GP GP TRAF5 TUBB4A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP GP GP G GP G GP P GP GP GP GP GP GP G TRAF5 CASP10 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP G G GP GP GP GP G TRAF5 TNFRSF18 25402006, 16082366 pred G G G G GP GP G G GP G GP G GP GP G G GP G GP G GP G G G G GP GP GP G TRAF5 IRAK3 25402006 pred GP GP G GP P GP GP P P GP GP G P P P G P GP P P GP GP GP P TRAF5 UBE2V1 25402006, 23023127 pred TRAF5 PLK1 25402006 pred P P G G GP P G GP GP P P P GP GP GP G GP G GP P GP GP GP P P GP TRAF5 NOD1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 DDX3X 25402006 pred G GP G G GP GP G G GP G G G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 TRAPPC9 21836163 pred G GP G G G GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G TRAF5 RNF216 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 FLNA 23023127 pred G G G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G TRAF5 BIRC2 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G PSMD11 TRAF5 25402006 pred G GP G G GP GP G GP GP G GP G GP G G G GP G G G GP G G G G G G GP G TRAF5 TNFRSF6B 25402006, 16082366 pred P P P P P P P P TRAF5 TUBB2A 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP G G TRAF5 TBK1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 IKBKE 25402006, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 WDR5 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 STUB1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 CD40LG 25402006 pred P P P P GP P P P G P TRAF5 TNFSF8 25402006 pred G G G G G G G G G G G G G G G G G G G G G TRAF5 LGALS1 23023127 pred G G G G GP GP G G GP G GP G GP GP G G GP G G G GP G G G G GP G GP G TRAF5 TNFRSF10D 16082366 pred G G G G G G G G G G G G G G G TNFRSF10A TRAF5 16082366 pred GP G G G G GP G GP GP G GP G GP G G GP GP G G G GP G GP G GP G GP GP G TRAF5 EDA2R 25402006 pred P P P G P P G P P G G G G GP P P P P G TRAF5 TUBB6 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G G GP GP G GP GP GP GP G TRAF5 PSMD6 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 TUBA3E 25402006 pred P P P P P P P P P P P P P TRAF5 STAT1 25402006 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP G G GP GP G GP G TRAF5 MAP2K3 25402006 pred P P P P P P P P P P P P P P P P P P P P TRAF5 DDX58 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G TRAF5 MAPK14 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G TRAF5 IKBKB 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 ARRB1 25402006 pred GP G G G GP GP G G GP G GP G GP G G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 TXN 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G GP G GP GP GP GP G TRAF5 TUBB4B 25402006 pred GP G G G G GP G G GP G G G G GP G GP GP G GP G GP GP GP G GP GP GP GP G TRAF5 MYD88 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRAF5 IRAK2 25402006 pred GP GP G G GP GP G P P G GP GP GP GP GP GP G G G GP GP GP G GP P TRAF5 TUBB2B 25402006 pred P P G P GP G GP G GP P P P G GP GP GP G GP GP GP P GP P G TRAF5 IRAK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O00463 - 9275204 - X 2 Q9Y6Q6 O00463 - 9685412 - X 2 O00463 Q15326-6 affinity chromatography technology 20138174 physical association X 2 O00463 two hybrid 25416956 direct interaction X 2 O00463 O94972 pull down 11279055 direct interaction X 2 Q8IUC6 O00463 affinity chromatography technology 14982987 physical association X 2 Q9BWF2 O00463 affinity chromatography technology 17544371 physical association X 2 Q9Y6R0 O00463 affinity chromatography technology 22593207 physical association X 2 Q9Y6R0 O00463 affinity chromatography technology 22593207 physical association X 2 Q9Y6R0 O00463 two hybrid 21988832 direct interaction X 2 O00463 affinity chromatography technology 23774506 physical association X 2 P04632 O00463 two hybrid 21988832 direct interaction X 2 G5EA09 O00463 two hybrid 25416956 direct interaction X 2 A0A024R7G8 O00463 two hybrid 25416956 direct interaction X 2 Q07011 O00463 affinity chromatography technology 15941918 physical association X 2 Q8NCF5 O00463 affinity chromatography technology 11435475 physical association X 2 O43353 O00463 affinity chromatography technology 9642260 physical association X 2 P28908-3 O00463 pull down 9511754 direct interaction X 2 P28908-3 O00463 pull down 8999898 direct interaction X 2 P28908-3 O00463 affinity chromatography technology 8999898 physical association X 2 B4DYW1 O00463 two hybrid 21988832 direct interaction X 2 Q9C0C9 O00463 affinity chromatography technology 23381138 physical association X 2 Q13114-2 O00463 fluorescent resonance energy transfer 15383523 direct interaction X 2 Q13114-2 O00463 affinity chromatography technology 21903422 physical association X 2 A0A024R5T5 O00463 two hybrid 22493164 direct interaction X 2 A0A024QZU0 O00463 affinity chromatography technology 11479302 physical association X 2 O00463 affinity chromatography technology 11562359 physical association X 2 O00463 affinity chromatography technology 21041727 physical association X 2 O00463 pull down 9511754 direct interaction X 2 O00463 affinity chromatography technology 12220533 physical association X 2 O00463 affinity chromatography technology 20676093 physical association X 2 O00463 pull down 9990007 direct interaction X 2 O00463 pull down 8790348 direct interaction X 2 Q52MB2 O00463 two hybrid 25416956 direct interaction X 2 O00463 affinity chromatography technology 23774506 physical association X 2 O14836 O00463 affinity chromatography technology 20676093 physical association X 2 O14836 O00463 two hybrid 10880535 direct interaction X 2 O14836 O00463 affinity chromatography technology 10880535 physical association X 2 Q7Z434-4 O00463 affinity chromatography technology 20161788 physical association X 2 Q7Z434-4 O00463 two hybrid 20161788 direct interaction X 2 Q99558 O00463 affinity chromatography technology 9275204 physical association X 2 P43489 O00463 affinity chromatography technology 15941918 physical association X 2 P43489 O00463 affinity chromatography technology 9488716 physical association X 2 P43489 O00463 pull down 9488716 direct interaction X 2 E9PZT5 O00463 two hybrid 12529173 direct interaction X 2 P14373 O00463 two hybrid 22493164 direct interaction X 2 Q9UBI1 O00463 two hybrid 21988832 direct interaction X 2 Q15717 O00463 affinity chromatography technology 23772036 physical association X 2 P0CG48 O00463 affinity chromatography technology 22593207 physical association X 2 P0CG48 O00463 affinity chromatography technology 20161788 physical association X 2 Q99683 O00463 affinity chromatography technology 9774977 physical association X 2 Q99683 O00463 affinity chromatography technology 10523862 physical association X 2 O95551 O00463 affinity chromatography technology 10764746 physical association X 2 Q8IW76 O00463 affinity chromatography technology 15121867 physical association X 2 Q8IW76 O00463 affinity chromatography technology 15121867 physical association X 2 O43318-4 O00463 affinity chromatography technology 17384642 physical association X 2 O00463 O00463 affinity chromatography technology 9718306 physical association X 2 O00463 O00463 two hybrid 22493164 direct interaction X 2 O00463 O00463 two hybrid 25416956 direct interaction X 2 O00463 Q9H8Y8 two hybrid 25416956 direct interaction X 2 O00463 P08138 affinity chromatography technology 10514511 physical association X 2 O60508 O00463 affinity chromatography technology 20614026 physical association X 2 O60508 O00463 affinity chromatography technology 20614026 physical association X 2 Q93009 O00463 pull down 11279055 direct interaction X 2 Q13287 O00463 two hybrid 25416956 direct interaction X 2 P36941 O00463 pull down 14517219 direct interaction X 2 P36941 O00463 pull down 9511754 direct interaction X 2 P36941 O00463 pull down 9162022 direct interaction X 2 Q9BZR9 O00463 two hybrid 22493164 direct interaction X 2 Q02223 O00463 affinity chromatography technology 20676093 physical association X 2 A0A024QZT4 O00463 two hybrid 25416956 direct interaction X 2 P55735 O00463 two hybrid 25416956 direct interaction X 2 A0A024R8H5 O00463 pull down 9718306 direct interaction X 2 A0A024R8H5 O00463 affinity chromatography technology 21903422 physical association X 2 A0A024R8H5 O00463 pull down 21903422 direct interaction X 2 Q00987 O00463 two hybrid 22493164 direct interaction X 2 Q80WM9 O00463 two hybrid 9153189 direct interaction X 2 Q9Y4K3 O00463 two hybrid 22493164 direct interaction X 2 Q9Y4K3 O00463 two hybrid 25416956 direct interaction X 2 P83436 O00463 affinity chromatography technology 21903422 physical association X 2 P83436 O00463 pull down 21903422 direct interaction X 2 Q16206 O00463 two hybrid 25416956 direct interaction X 2 Q9UP83-2 O00463 affinity chromatography technology 21903422 physical association X 2 Q9Y6Q6 O00463 affinity chromatography technology 9774460 physical association X 2 Q9Y6Q6 O00463 pull down 9685412 direct interaction X 2 Q9Y6Q6 O00463 pull down 10075662 direct interaction X 2 Q9Y6Q6 O00463 pull down 9852070 direct interaction X 2 P97525 O00463 two hybrid 8999898 direct interaction X 2 O00463 affinity chromatography technology 9582383 physical association X 2 A0A024R052 O00463 two hybrid 9153189 direct interaction X 2 A0A024R052 O00463 affinity chromatography technology 9153189 physical association X 2 A0A024R052 O00463 pull down 9162022 direct interaction X 2 Q9NVV9-2 O00463 two hybrid 25416956 direct interaction X 2 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 in vivo 11035039,11882293 - C 5 O00463 O94972 in vitro 11279055 - X 2 O00463 O94972 in vitro 11279055 - X 2 O00463 in vivo 11971184,8999898 - X 2 O00463 in vitro 11971184,8999898 - X 2 O00463 two hybrid 11971184,8999898 - X 2 O00463 in vivo 11971184,8999898 - X 2 O00463 in vitro 11971184,8999898 - X 2 O00463 two hybrid 11971184,8999898 - X 2 O43353 O00463 in vivo 9642260 - X 2 O43353 O00463 in vivo 9642260 - X 2 Q9NS68-2 O00463 in vivo 10809768 - X 2 Q9NS68-2 O00463 in vivo 10809768 - X 2 O00463 in vivo 9488716 - X 2 O00463 in vitro 9488716 - X 2 O00463 in vivo 9488716 - X 2 O00463 in vitro 9488716 - X 2 A6NHG8 O00463 in vivo 9718306 - X 2 A6NHG8 O00463 in vitro 9718306 - X 2 A6NHG8 O00463 in vitro 9718306 - X 2 A6NHG8 O00463 in vivo 9718306 - X 2 A0A024QZU0 O00463 in vivo 11479302 - X 2 A0A024QZU0 O00463 in vivo 11479302 - X 2 P25942-2 O00463 two hybrid 8790348,9990007 - X 2 P25942-2 O00463 in vitro 8790348,9990007 - X 2 P25942-2 O00463 in vitro 8790348,9990007 - X 2 P25942-2 O00463 two hybrid 8790348,9990007 - X 2 Q99558 O00463 in vitro 9275204 - X 2 Q99558 O00463 in vivo 9275204 - X 2 Q99558 O00463 in vitro 9275204 - X 2 Q99558 O00463 in vivo 9275204 - X 2 Q99683 O00463 in vitro 10523862 - X 2 Q99683 O00463 in vivo 10523862 - X 2 Q99683 O00463 in vivo 10523862 - X 2 Q99683 O00463 in vitro 10523862 - X 2 O43734-2 O00463 in vitro 12089335 - X 2 O43734-2 O00463 in vivo 12089335 - X 2 O43734-2 O00463 in vivo 12089335 - X 2 O43734-2 O00463 in vitro 12089335 - X 2 O95551 O00463 in vivo 10764746 - X 2 O95551 O00463 in vivo 10764746 - X 2 O00463 in vitro 10880535 - X 2 O00463 in vivo 10880535 - X 2 O00463 in vitro 10880535 - X 2 O00463 in vivo 10880535 - X 2 O00463 O00463 two hybrid 9153189,9162022 - X 2 O00463 O00463 in vivo 9153189,9162022 - X 2 Q93009 O00463 in vitro 11279055 - X 2 Q93009 O00463 in vitro 11279055 - X 2 O00463 in vivo 8663299 - X 2 O00463 in vitro 8663299 - X 2 O00463 in vivo 8663299 - X 2 O00463 in vitro 8663299 - X 2 Q00994-2 O00463 in vivo 10514511 - X 2 Q00994-2 O00463 in vivo 10514511 - X 2 Q9Y6Q6 O00463 in vitro 10025951,9774460 - X 2 Q9Y6Q6 O00463 in vitro 10025951,9774460 - X 2 Q9NP84 O00463 two hybrid 12529173 - X 2 Q9NP84 O00463 in vitro 12529173 - X 2 Q9NP84 O00463 two hybrid 12529173 - X 2 Q9NP84 O00463 in vitro 12529173 - X 2 O00463 in vivo 9582383 - X 2 O00463 in vivo 9582383 - X 2 O00463 two hybrid 9153189 - X 2 O00463 in vivo 9153189 - X 2 O00463 in vivo 9153189 - X 2 O00463 two hybrid 9153189 - X 2 O00463 pull down 20676093 association C 4 Q07955 O00463 anti tag coimmunoprecipitation 21822258 physical association X 2 O00463 anti bait coimmunoprecipitation 21822258 association C 3 O00463 anti bait coimmunoprecipitation 21822258 association C 3 Q8WTW2 O00463 two hybrid prey pooling approach 25416956 physical association X 2 Q8WTW2 O00463 two hybrid array 25416956 physical association X 2 Q8WTW2 O00463 validated two hybrid 25416956 physical association X 2 P04632 O00463 two hybrid array 21988832 physical association X 2 A0A024R7G8 O00463 two hybrid prey pooling approach 25416956 physical association X 2 A0A024R7G8 O00463 two hybrid array 25416956 physical association X 2 A0A024R7G8 O00463 validated two hybrid 25416956 physical association X 2 Q86XP1 O00463 two hybrid array 21988832 physical association X 2 Q9UHP3 O00463 anti bait coimmunoprecipitation 23042150 physical association X 2 Q52MB2 O00463 two hybrid prey pooling approach 25416956 physical association X 2 Q52MB2 O00463 two hybrid array 25416956 physical association X 2 Q52MB2 O00463 validated two hybrid 25416956 physical association X 2 P14373 O00463 two hybrid array 22493164 physical association X 2 Q9UBI1 O00463 two hybrid array 21988832 physical association X 2 O00463 pull down 20676093 association C 3 O00463 pull down 20676093 association C 6 O00463 anti bait coimmunoprecipitation 20676093 association C 3 O00463 coimmunoprecipitation 20676093 association C 6 Q15326 O00463 anti tag coimmunoprecipitation 20138174 physical association X 2 O00463 O00463 two hybrid array 22493164 physical association X 2 O00463 O00463 two hybrid array 25416956 physical association X 2 O00463 Q9H8Y8 two hybrid prey pooling approach 25416956 physical association X 2 O00463 Q9H8Y8 two hybrid array 25416956 physical association X 2 O00463 Q9H8Y8 validated two hybrid 25416956 physical association X 2 Q13287 O00463 two hybrid 21516116 physical association X 2 Q13287 O00463 two hybrid prey pooling approach 25416956 physical association X 2 Q13287 O00463 two hybrid array 25416956 physical association X 2 Q13287 O00463 validated two hybrid 25416956 physical association X 2 Q9BZR9 O00463 two hybrid array 22493164 physical association X 2 Q8N7N6 O00463 anti tag coimmunoprecipitation 21822258 physical association X 2 A0A024R7Z5 O00463 two hybrid prey pooling approach 25416956 physical association X 2 A0A024R7Z5 O00463 two hybrid array 25416956 physical association X 2 A0A024R7Z5 O00463 validated two hybrid 25416956 physical association X 2 A0A024QZT4 O00463 two hybrid prey pooling approach 25416956 physical association X 2 A0A024QZT4 O00463 two hybrid array 25416956 physical association X 2 A0A024QZT4 O00463 validated two hybrid 25416956 physical association X 2 P55735 O00463 two hybrid prey pooling approach 25416956 physical association X 2 P55735 O00463 two hybrid array 25416956 physical association X 2 P55735 O00463 validated two hybrid 25416956 physical association X 2 A0A024RDM5 O00463 anti tag coimmunoprecipitation 10809768 physical association X 2 Q6FIF0 O00463 two hybrid prey pooling approach 25416956 physical association X 2 Q6FIF0 O00463 two hybrid array 25416956 physical association X 2 Q6FIF0 O00463 validated two hybrid 25416956 physical association X 2 Q9APZ2 O00463 two hybrid pooling approach 20711500 physical association X 2 Q13114 O00463 proximity ligation assay 25241761 physical association X 2 Q6ZNA4 O00463 two hybrid array 22493164 physical association X 2 Q00987 O00463 two hybrid array 22493164 physical association X 2 Q9Y4K3 O00463 two hybrid 21516116 physical association X 2 Q9Y4K3 O00463 two hybrid 21516116 physical association X 2 Q9Y4K3 O00463 two hybrid array 22493164 physical association X 2 Q9Y4K3 O00463 two hybrid prey pooling approach 25416956 physical association X 2 Q9Y4K3 O00463 two hybrid prey pooling approach 25416956 physical association X 2 Q9Y4K3 O00463 two hybrid array 25416956 physical association X 2 Q9Y4K3 O00463 two hybrid array 25416956 physical association X 2 Q9Y4K3 O00463 validated two hybrid 25416956 physical association X 2 Q16206-2 O00463 two hybrid prey pooling approach 25416956 physical association X 2 Q16206-2 O00463 two hybrid array 25416956 physical association X 2 Q16206-2 O00463 validated two hybrid 25416956 physical association X 2 Q9Y6Q6 O00463 anti tag coimmunoprecipitation 10075662 physical association X 2 A0A024R052 O00463 two hybrid 9153189 physical association X 2 A0A024R052 O00463 coimmunoprecipitation 9153189 physical association X 2 A0A024R052 O00463 two hybrid 9153189 physical association X 2 A0A024R052 O00463 two hybrid 9153189 physical association X 2 A0A024R052 O00463 pull down 9162022 physical association X 2 Q9NVV9 O00463 two hybrid prey pooling approach 25416956 physical association X 2 Q9NVV9 O00463 two hybrid array 25416956 physical association X 2 Q9NVV9 O00463 validated two hybrid 25416956 physical association X 2 Q9Y6Q6 O00463 coimmunoprecipitation 9685412 - X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TRAF5 TRIM37 MI:0096(pull down)|MI:0492(in vitro) 11279055 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_113918|HPRD_10697 prey|- bait|- TRAF5 TNFRSF17 MI:0004(affinity chromatography technology)|MI:0096(pull down) 20676093 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_253660|UniProt_108352 prey|prey bait|bait TRAF5 RIPK2 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 9642260 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_97268|HPRD_10693 prey|- bait|- TRAF5 MAP3K7 MI:0004(affinity chromatography technology) 17384642 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_211670 prey bait TRAF5 ZMYND11 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20138174 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0471(mint) BIOGRID_220635|MINT_76034|UniProt_105906|MINT_45566 bait|bait|bait|bait prey|prey|prey|prey TRAF5 TRAF3IP2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo) 12089335,21822258 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|- (intact)|(intact)|MI:0468(hprd) UniProt_115578|UniProt_115577|HPRD_25600 bait|prey|- prey|bait|- TRAF5 USP25 MI:0006(anti bait coimmunoprecipitation) 23042150 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_124308 bait prey TRAF5 SMURF1 MI:0018(two hybrid) 19937093 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0796(suppressive genetic interaction defined by inequality) (biogrid) BIOGRID_135098 bait prey TRAF5 COG5 MI:0004(affinity chromatography technology) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_155848 bait prey TRAF5 RNF111 MI:0415(enzymatic study)|MI:0397(two hybrid array) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_284120|UniProt_122439 prey|bait bait|prey TRAF5 COMMD3 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_285470|UniProt_117826 prey|unspecified role bait|unspecified role TRAF5 NMI MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114573 bait prey TRAF5 TRAF3 MI:0055(fluorescent resonance energy transfer)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 15383523,21903422,9718306 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_210045|BIOGRID_155851|HPRD_25547 prey|bait|- bait|prey|- TRAF5 RIPK1 MI:0096(pull down)|MI:0493(in vivo) 11479302 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_106344|HPRD_10692 prey|- bait|- TRAF5 MAP3K14 MI:0492(in vitro)|MI:0004(affinity chromatography technology) 9275204 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_18586|BIOGRID_211612 -|bait -|prey TRAF5 MAP3K5 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 10523862,9774977 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_97919|HPRD_10689|BIOGRID_102426 bait|-|prey prey|-|bait TRAF5 COG7 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_156003|BIOGRID_155849 bait|bait prey|prey TRAF5 UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20161788,22593207 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_154029|BIOGRID_247768 bait|bait prey|prey TRAF5 MDM2 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122469|BIOGRID_284068 bait|prey prey|bait TRAF5 NGFRAP1 MI:0493(in vivo) 10514511 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_30588 - - TRAF5 MAVS MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20161788 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_154027|BIOGRID_154028 prey|prey bait|bait TRAF5 NFATC2IP MI:0004(affinity chromatography technology) 11435475 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_218295 bait prey TRAF5 SRSF1 MI:0007(anti tag coimmunoprecipitation) 21822258 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_115575 bait prey TRAF5 TNFRSF14 MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid) 9153189,9162022 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction) (biogrid)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|MI:0468(hprd)|(biogrid) BIOGRID_112377|UniProt_177142|UniProt_134453|BIOGRID_101838|UniProt_135002|UniProt_135003|UniProt_134997|UniProt_135005|UniProt_177148|UniProt_177147|HPRD_10691|BIOGRID_101833 prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|-|prey bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|-|bait TRAF5 TICAM1 MI:0004(affinity chromatography technology) 14982987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_195436 prey bait TRAF5 LTBR MI:0114(x-ray crystallography)|MI:0096(pull down)|MI:0492(in vitro)|MI:0096(pull down) 14517219,8663299,9162022,9511754 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|-|MI:0407(direct interaction) (biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_213142|BIOGRID_112386|HPRD_8096|BIOGRID_213434 prey|prey|-|prey bait|bait|-|bait TRAF5 TNFRSF9 MI:0004(affinity chromatography technology) 15941918 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_213011 bait prey TRAF5 NGFR MI:0004(affinity chromatography technology) 10514511 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_104856 prey bait TRAF5 USP7 MI:0096(pull down)|MI:0492(in vitro) 11279055 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_113925|HPRD_10690 prey|- bait|- TRAF5 TRIM8 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122583|BIOGRID_284128 prey|prey bait|bait TRAF5 TRAIP MI:0096(pull down) 17544371 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_141914 prey bait TRAF5 TRAF6 MI:0492(in vitro)|MI:0397(two hybrid array)|MI:0415(enzymatic study)|MI:0018(two hybrid)|MI:0018(two hybrid) 11882293,21516116,22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(intact)|(biogrid)|(intact)|(intact) HPRD_40598|UniProt_122416|BIOGRID_283985|UniProt_114627|UniProt_114572 -|bait|prey|prey|bait -|prey|bait|bait|prey TRAF5 UBE2O MI:0004(affinity chromatography technology) 23381138 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_250000 bait prey TRAF5 NUMBL MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832,22593207 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(intact)|(biogrid) BIOGRID_247765|BIOGRID_247766|UniProt_119312|BIOGRID_286614 bait|prey|unspecified role|prey prey|bait|unspecified role|bait TRAF5 TNFRSF11A MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0492(in vitro) 10075662,9685412,9774460,9852070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|- (biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|MI:0468(hprd) BIOGRID_106902|BIOGRID_211153|BIOGRID_106685|BIOGRID_113754|UniProt_65899|HPRD_10695 prey|prey|prey|prey|prey|- bait|bait|bait|bait|bait|- TRAF5 TRAF2 MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 11882293,21903422,9718306 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_40598|BIOGRID_156004|BIOGRID_212594|BIOGRID_155850 -|bait|bait|bait -|prey|prey|prey TRAF5 TNFRSF13B MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0096(pull down) 10880535,20676093 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0914(association) (intact)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(intact) UniProt_108351|BIOGRID_113877|BIOGRID_113874|BIOGRID_253656|HPRD_10696|UniProt_108367 prey|bait|prey|prey|-|prey bait|prey|bait|bait|-|bait TRAF5 CD40 MI:0096(pull down)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 11562359,12220533,20676093,21041727,8790348,9511754,9990007 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact) BIOGRID_110539|HPRD_6045|BIOGRID_253664|BIOGRID_212737|BIOGRID_98243|BIOGRID_213432|BIOGRID_217148|BIOGRID_213094|UniProt_108353 prey|-|prey|prey|prey|prey|bait|prey|prey bait|-|bait|bait|bait|bait|prey|bait|bait TRAF5 CD27 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 9582383 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_111872|HPRD_3314 prey|- bait|- TRAF5 TRIM27 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122496|BIOGRID_284118 bait|bait prey|prey TRAF5 CDC40 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20614026 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_200979|BIOGRID_200991 prey|prey bait|bait TRAF5 CAPNS1 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_116863|BIOGRID_286613 unspecified role|prey unspecified role|bait TRAF5 DGKH MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_285471|UniProt_118311 prey|unspecified role bait|unspecified role TRAF5 TNFRSF4 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15941918,9488716 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_6805|BIOGRID_213016|BIOGRID_102217|BIOGRID_102218 -|bait|prey|prey -|prey|bait|bait TRAF5 TNFRSF19 MI:0493(in vivo)|MI:0007(anti tag coimmunoprecipitation) 10809768 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(intact) HPRD_10699|UniProt_66075 -|bait -|prey TRAF5 TDP2 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10764746 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_102200|HPRD_10698 bait|- prey|- TRAF5 TNFRSF8 MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0493(in vivo) 8999898,9511754 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_107891|BIOGRID_107888|BIOGRID_213433|HPRD_37171 prey|prey|prey|- bait|bait|bait|- TRAF5 TNFRSF12A MI:0492(in vitro) 12529173 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_30547 - -

PPI - HINT Gene A Gene B PMID Method Quality TRAF5 TNFRSF13B 20676093,20676093,10880535,10880535 0019,0096,0004,0018 LC TRAF5 CD40 8790348,9990007,20676093,20614026,17332487,20676093,11562359,21041727,8790348,9511754,12220533,9990007 0018,0018,0004,0004,0007,0096,0004,0004,0096,0096,0004,0096 LC TRAF5 TNFRSF8 8999898,11971184,11971184,8999898,8999898,9511754 0004,0018,0007,0018,0096,0096 LC TRAF5 LTBR 14517219,9511754,9162022 0096,0096,0096 LC TRAF5 TNFRSF4 9488716,15941918,15941918,9488716 0004,0007,0004,0096 LC TRAF5 TRAF2 21903422,9718306,21903422 0096,0096,0004 LC TRAF5 TRAF3 25241761,9718306,25241761,21903422 0813,0007,0428,0004 LC TRAF5 TACI 10880535,20676093,10880535 0018,0004,0004 LC TRAF5 MAVS 20161788,26221961,20161788,20161788 0007,0004,0004,0018 LC TRAF5 HOMER1 26186194 0004 HT TRAF5 TNFRSF14 9153189,9153189,9162022,9153189 0018,0019,0096,0004 LC TRAF5 MAP3K5 9774977,10523862 0004,0004 LC TRAF5 LZTS2 26186194 0004 HT TRAF5 TNFRSF11A 9774460,9685412,9852070,10075662,9685412,10075662,9685412 0004,0096,0096,0007,0007,0096,0019 LC TRAF5 HOMER1 26186194 0004 HT TRAF5 LZTS2 26186194 0004 HT TRAF5 TNFRSF13B 20676093,20676093,10880535,10880535 0019,0096,0004,0018 LC TRAF5 CD40 8790348,9990007,20676093,20614026,17332487,20676093,11562359,21041727,8790348,9511754,12220533,9990007 0018,0018,0004,0004,0007,0096,0004,0004,0096,0096,0004,0096 LC TRAF5 TNFRSF8 8999898,11971184,11971184,8999898,8999898,9511754 0004,0018,0007,0018,0096,0096 LC TRAF5 LTBR 14517219,9511754,9162022 0096,0096,0096 LC TRAF5 TNFRSF4 9488716,15941918,15941918,9488716 0004,0007,0004,0096 LC TRAF5 TRAF2 21903422,9718306,21903422 0096,0096,0004 LC TRAF5 TRAF3 25241761,9718306,25241761,21903422 0813,0007,0428,0004 LC TRAF5 TACI 10880535,20676093,10880535 0018,0004,0004 LC TRAF5 MAVS 20161788,26221961,20161788,20161788 0007,0004,0004,0018 LC TRAF5 TNFRSF14 9153189,9153189,9162022,9153189 0018,0019,0096,0004 LC TRAF5 MAP3K5 9774977,10523862 0004,0004 LC TRAF5 TNFRSF11A 9774460,9685412,9852070,10075662,9685412,10075662,9685412 0004,0096,0096,0007,0007,0096,0019 LC TRAF5 TRAF5 22493164,15383523,25416956,25416956,9162022,22493164,9153189 0018,0055,0397,0018,0018,0397,0018 HT,LC TRAF5 SDCBP 27107012,25416956,25416956,25416956,25416956,27107012 1356,1112,0397,0018,1356,2215 HT TRAF5 TNFRSF13B 20676093,20676093,10880535,10880535 0019,0096,0004,0018 LC TRAF5 CAPNS1 21988832,21988832 0397,0018 HT TRAF5 TRIM27 22493164,22493164 0018,0397 HT TRAF5 CD40 8790348,9990007,8790348,9990007 0018,0018,0096,0096 LC TRAF5 TNFRSF8 8999898,11971184,11971184,8999898,8999898 0004,0018,0007,0018,0096 LC TRAF5 SERPINB9 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF5 RAD23A 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF5 SEC13 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF5 MDM2 22493164,22493164 0018,0397 HT TRAF5 GOLGA2 27107012,27107012 1356,2215 HT TRAF5 TRAF3 20161788,15383523 0018,0055 LC TRAF5 NMI 27107012,21516116,25416956,25416956,25416956,25416956,27107012 1356,0018,1112,0397,0018,1356,2215 HT TRAF5 ENOX2 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF5 TACI 10880535,10880535 0018,0004 LC TRAF5 CCDC184 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF5 ZFAND6 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF5 RNF111 22493164,22493164 0018,0397 HT TRAF5 MAVS 20161788,20161788,20161788 0007,0004,0018 LC TRAF5 DGKH 21988832,21988832 0397,0018 HT TRAF5 TNFRSF14 9153189,9153189,9153189 0018,0019,0004 LC TRAF5 MAP3K14 9275204,9275204 0019,0004 LC TRAF5 HSD17B10 22496890 0018 LC TRAF5 TRIM8 22493164,22493164 0018,0397 HT TRAF5 GORASP2 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF5 TNFRSF12A 12529173 0018 LC TRAF5 THAP1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF5 COMMD3 21988832,21988832 0397,0018 HT TRAF5 TRAF6 27107012,22493164,21516116,25416956,25416956,25416956,22493164,25416956,27107012 1356,0018,0018,1112,0397,0018,0397,1356,2215 HT TRAF5 TNFRSF11A 9685412,9685412,9685412 0096,0007,0019 LC TRAF5 NUMBL 21988832 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID O43318 O00463 MAP3K7 TRAF5 0.21 17384642 O43353 O00463 RIPK2 TRAF5 0.21 9642260 Q9H8Y8 O00463 GORASP2 TRAF5 0.454 25416956 Q8IUC6 O00463 TICAM1 TRAF5 0.21 14982987 P08138 O00463 NGFR TRAF5 0.21 10514511 O94972 O00463 TRIM37 TRAF5 0.309 11279055 P04601 O00463 NEF TRAF5 0.21 23774506 Q9Y6R0 O00463 NUMBL TRAF5 0.583 21988832,22593207 Q8IZU1 O00463 FAM9A TRAF5 0.236 unassigned1304 Q9NVF7 O00463 FBXO28 TRAF5 0.236 unassigned1304 P04632 O00463 CAPNS1 TRAF5 0.286 21988832 Q8TBB1 O00463 LNX1 TRAF5 0.236 unassigned1304 Q96Q77 O00463 CIB3 TRAF5 0.236 unassigned1304 Q96HA8 O00463 WDYHV1 TRAF5 0.236 unassigned1304 Q9BT49 O00463 THAP7 TRAF5 0.236 unassigned1304 Q9BZR9 O00463 TRIM8 TRAF5 0.286 22493164 O00463 A4D127 TRAF5 MEOX2 {ECO:0000313|EMBL:EAL24289.1} 0.236 unassigned1304 Q12933 O00463 TRAF2 TRAF5 0.623 21903422,unassigned1304,9718306 Q00987 O00463 MDM2 TRAF5 0.286 22493164 Q52MB2 O00463 CCDC184 TRAF5 0.583 25416956,unassigned1304 Q5BJF6 O00463 ODF2 TRAF5 0.236 unassigned1304 P78317 O00463 RNF4 TRAF5 0.236 unassigned1304 P62699 O00463 YPEL5 TRAF5 0.236 unassigned1304 P55735 O00463 SEC13 TRAF5 0.583 25416956,unassigned1304 P54725 O00463 RAD23A TRAF5 0.454 25416956 O00463 A0A0C4DGS5 TRAF5 A0A0C4DGS5 0.236 27107012 O00463 G2XKQ0 TRAF5 G2XKQ0 0.236 unassigned1304 P83436 O00463 COG7 TRAF5 0.286 21903422 Q13114 O00463 TRAF3 TRAF5 0.629 15383523,unassigned1304,25241761,21903422 Q92956 O00463 TNFRSF14 TRAF5 0.837 9162022,9153189 Q16543 O00463 CDC37 TRAF5 0.236 unassigned1304 Q49A26 O00463 GLYR1 TRAF5 0.236 unassigned1304 Q9NRD5 O00463 PICK1 TRAF5 0.236 unassigned1304 P25786 O00463 PSMA1 TRAF5 0.236 unassigned1304 O00463 A0A087WUI6 TRAF5 PIBF1 {ECO:0000313|ENSEMBL:ENSP00000478697} 0.236 unassigned1304 O75031 O00463 HSF2BP TRAF5 0.236 unassigned1304 O75928 O00463 PIAS2 TRAF5 0.236 unassigned1304 O95995 O00463 GAS8 TRAF5 0.236 unassigned1304 P63165 O00463 SUMO1 TRAF5 0.236 unassigned1304 P61968 O00463 LMO4 TRAF5 0.236 unassigned1304 P36941 O00463 LTBR TRAF5 0.671 9162022,9511754,14517219 Q7Z434 O00463 MAVS TRAF5 0.569 20161788,26221961 Q86YM7 O00463 HOMER1 TRAF5 0.332 unassigned1304,26186194 O00560 O00463 SDCBP TRAF5 0.681 25416956,27107012,unassigned1304 P28908 O00463 TNFRSF8 TRAF5 0.623 8999898,9511754 Q13287 O00463 NMI TRAF5 0.787 25416956,27107012,unassigned1304,21516116 Q6FIF0 O00463 ZFAND6 TRAF5 0.454 25416956 Q9Y4K3 O00463 TRAF6 TRAF5 0.891 25416956,unassigned1304,22493164,21516116,27107012 Q9NVV9 O00463 THAP1 TRAF5 0.583 25416956,unassigned1304 O00463 O00463 TRAF5 TRAF5 0.757 25416956,22493164,9718306,unassigned1304 Q93009 O00463 USP7 TRAF5 0.309 11279055 Q99714 O00463 HSD17B10 TRAF5 0.183 22496890 Q9BRK4 O00463 LZTS2 TRAF5 0.126 26186194 P26842 O00463 CD27 TRAF5 0.21 9582383 Q9BWF2 O00463 TRAIP TRAF5 0.21 17544371 Q9CR75 O00463 TNFRSF12A TRAF5 0.309 12529173 Q99683 O00463 MAP3K5 TRAF5 0.376 9774977,10523862 Q9UBI1 O00463 COMMD3 TRAF5 0.286 21988832 Q13546 O00463 RIPK1 TRAF5 0.21 11479302 P97525 O00463 TNFRSF8 TRAF5 0.309 8999898 Q15326 O00463 ZMYND11 TRAF5 0.376 20138174 P19525 O00463 EIF2AK2 TRAF5 0.376 15121867 P51449 O00463 RORC TRAF5 0.376 26453305 Q02223 O00463 TNFRSF17 TRAF5 0.21 20676093 Q16206 O00463 ENOX2 TRAF5 0.454 25416956 O14836 O00463 TNFRSF13B TRAF5 0.569 10880535,20676093 O43734 O00463 TRAF3IP2 TRAF5 0.376 21822258 O95551 O00463 TDP2 TRAF5 0.21 10764746 P14373 O00463 TRIM27 TRAF5 0.286 22493164 P25942 O00463 CD40 TRAF5 0.899 9990007,20676093,20614026,9511754,11562359,8790348,12220533,21041727 P38340 O00463 TAE1 TRAF5 0.332 27107014 P43489 O00463 TNFRSF4 TRAF5 0.569 9488716,15941918 P50453 O00463 SERPINB9 TRAF5 0.583 25416956,unassigned1304 Q07011 O00463 TNFRSF9 TRAF5 0.21 15941918 Q07955 O00463 SRSF1 TRAF5 0.21 21822258 Q15717 O00463 ELAVL1 TRAF5 0.21 23772036 Q6PDM2 O00463 SRSF1 TRAF5 0.21 21822258 Q6ZNA4 O00463 RNF111 TRAF5 0.286 22493164 Q86XP1 O00463 DGKH TRAF5 0.286 21988832 Q8NCF5 O00463 NFATC2IP TRAF5 0.21 11435475 Q8WTW2 O00463 NMI {ECO:0000313|EMBL:AAH21987.1} TRAF5 0.332 25416956 Q99558 O00463 MAP3K14 TRAF5 0.21 9275204 Q9APZ2 O00463 RECA TRAF5 0.126 20711500 Q9C0C9 O00463 UBE2O TRAF5 0.21 23381138 Q9NS68 O00463 TNFRSF19 TRAF5 0.21 10809768 Q9UP83 O00463 COG5 TRAF5 0.126 21903422 Q9Y6Q6 O00463 TNFRSF11A TRAF5 0.794 9774460,10075662,9852070,9685412

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 TRAF5 SDCBP MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFRSF13B MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 IKBKB MI:0362 inference MI:0461 interaction database TRAF5 MAP3K7 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 RIPK2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TRAF3IP2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 CDC40 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TRIM37 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TDP2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNF MI:0362 inference MI:0461 interaction database TRAF5 CAPNS1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 NGFR MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 UBC MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TRIM27 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFRSF1A MI:0362 inference MI:0461 interaction database TRAF5 EIF2AK2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFAIP3 MI:0362 inference MI:0461 interaction database TRAF5 CD40 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 CD27 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFRSF8 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 LTBR MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 HNF4A MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFRSF4 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 CAMLG MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 SERPINB9 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 RORC MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 IRAK1 MI:0362 inference MI:0461 interaction database TRAF5 RAD23A MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 SEC13 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 COG7 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 MDM2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFRSF17 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFRSF9 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 SRSF1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TRAF2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TRAF3 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 NMI MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 RIPK1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 IKBKE MI:0362 inference MI:0461 interaction database TRAF5 ZMYND11 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TRADD MI:0362 inference MI:0461 interaction database TRAF5 ELAVL1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 ENOX2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 E2F4 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 CCDC184 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 ZFAND6 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 RNF111 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 MAVS MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 DGKH MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 HOMER1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TICAM1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 NFATC2IP MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFRSF14 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 USP7 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 RNF31 MI:0362 inference MI:0461 interaction database TRAF5 MAP3K14 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TRAF5 MAP3K5 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 HSD17B10 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 MYD88 MI:0362 inference MI:0461 interaction database TRAF5 LZTS2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 NTMT1 MI:0362 inference MI:0461 interaction database TRAF5 TRAIP MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TRIM8 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 UBE2O MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 GORASP2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TNFRSF12A MI:0362 inference MI:0461,MI:1106 interaction database,pathways database TRAF5 CYLD MI:0362 inference MI:0461 interaction database TRAF5 TNFRSF19 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 THAP1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 IRAK4 MI:0362 inference MI:0461 interaction database TRAF5 COMMD3 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 USP25 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 COG5 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database TRAF5 IKBKG MI:0362 inference MI:0461 interaction database TRAF5 TNFRSF11A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TRAF5 NUMBL MI:0045 experimental interaction detection MI:0461 interaction database