| PTM - CPLM | | Gene Name | UniProt ID | Type | Position | Code |
|---|
| FUS; TLS | P35637 | Ubiquitination | 316 | K | | FUS; TLS | P35637 | Ubiquitination | 365 | K | | FUS; TLS | P35637 | Ubiquitination | 315 | K | | FUS; TLS | P35637 | Ubiquitination | 348 | K | |
| PTM - dbPAF | | Gene Name | UniProt ID | Position | Type | Species |
|---|
| FUS; TLS | P35637 | 131 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 19 | T | Homo sapiens(Human) | | FUS; TLS | P35637 | 221 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 232 | Y | Homo sapiens(Human) | | FUS; TLS | P35637 | 257 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 26 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 273 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 277 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 282 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 286 | T | Homo sapiens(Human) | | FUS; TLS | P35637 | 304 | Y | Homo sapiens(Human) | | FUS; TLS | P35637 | 317 | T | Homo sapiens(Human) | | FUS; TLS | P35637 | 325 | Y | Homo sapiens(Human) | | FUS; TLS | P35637 | 326 | T | Homo sapiens(Human) | | FUS; TLS | P35637 | 340 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 346 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 397 | Y | Homo sapiens(Human) | | FUS; TLS | P35637 | 42 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 462 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 468 | Y | Homo sapiens(Human) | | FUS; TLS | P35637 | 61 | S | Homo sapiens(Human) | | FUS; TLS | P35637 | 84 | S | Homo sapiens(Human) | |
| PTM - PhosphositePlus | | UniProt ID | MOD_RSD | Type | SITE_+/-7_AA |
|---|
| P35637 | K332-ac | Acetylation | ytDRETGkLkGEATV | | P35637 | K357-ac | Acetylation | AIDWFdGkEFsGNPI | | P35637 | R213-m1 | Methylation | GGYGQQDrGGrGrGG | | P35637 | R216-m1 | Methylation | GQQDrGGrGrGGsGG | | P35637 | R216-m2 | Methylation | GQQDrGGrGrGGsGG | | P35637 | R218-m1 | Methylation | QDrGGrGrGGsGGGG | | P35637 | R218-m2 | Methylation | QDrGGrGrGGsGGGG | | P35637 | R234-m1 | Methylation | GGGGGyNrSSGGYEP | | P35637 | R242-m1 | Methylation | SSGGYEPrGrGGGrG | | P35637 | R242-m2 | Methylation | SSGGYEPrGrGGGrG | | P35637 | R244-m1 | Methylation | GGYEPrGrGGGrGGr | | P35637 | R244-m2 | Methylation | GGYEPrGrGGGrGGr | | P35637 | R248-m2 | Methylation | PrGrGGGrGGrGGMG | | P35637 | R248-m1 | Methylation | PrGrGGGrGGrGGMG | | P35637 | R251-m2 | Methylation | rGGGrGGrGGMGGsD | | P35637 | R259-m2 | Methylation | GGMGGsDrGGFNkFG | | P35637 | R259-m1 | Methylation | GGMGGsDrGGFNkFG | | P35637 | R269-m1 | Methylation | FNkFGGPrDQGsRHD | | P35637 | K365-m1 | Methylation | EFsGNPIkVSFATrr | | P35637 | R371-m1 | Methylation | IkVSFATrrADFNRG | | P35637 | R372-m1 | Methylation | kVSFATrrADFNRGG | | P35637 | R394-m2 | Methylation | GRGGPMGrGGyGGGG | | P35637 | R394-m1 | Methylation | GRGGPMGrGGyGGGG | | P35637 | R407-m1 | Methylation | GGSGGGGrGGFPSGG | | P35637 | R407-m2 | Methylation | GGSGGGGrGGFPSGG | | P35637 | R473-m1 | Methylation | GNyGDDRrGGrGGYD | | P35637 | R476-m1 | Methylation | GDDRrGGrGGYDrGG | | P35637 | R481-m1 | Methylation | GGrGGYDrGGYrGrG | | P35637 | R485-m1 | Methylation | GYDrGGYrGrGGDrG | | P35637 | R487-m1 | Methylation | DrGGYrGrGGDrGGF | | P35637 | R491-m2 | Methylation | YrGrGGDrGGFrGGr | | P35637 | R491-m1 | Methylation | YrGrGGDrGGFrGGr | | P35637 | R495-m2 | Methylation | GGDrGGFrGGrGGGD | | P35637 | R495-m1 | Methylation | GGDrGGFrGGrGGGD | | P35637 | R498-m2 | Methylation | rGGFrGGrGGGDrGG | | P35637 | R503-m2 | Methylation | GGrGGGDrGGFGPGK | | P35637 | R503-m1 | Methylation | GGrGGGDrGGFGPGK | | P35637 | R514-m1 | Methylation | GPGKMDSrGEHRQDR | | P35637 | T19-gl | O-GlcNAc | QSYGAYPtQPGQGYs | | P35637 | S26-p | Phosphorylation | tQPGQGYsQQSSQPY | | P35637 | S42-p | Phosphorylation | QQSYSGYsQSTDTSG | | P35637 | S61-p | Phosphorylation | SYSSYGQsQNTGYGT | | P35637 | S84-p | Phosphorylation | STGGYGSsQSSQSSY | | P35637 | S131-p | Phosphorylation | QPQSGSYsQQPSYGG | | P35637 | S221-p | Phosphorylation | GGrGrGGsGGGGGGG | | P35637 | Y232-p | Phosphorylation | GGGGGGGyNrSSGGY | | P35637 | S257-p | Phosphorylation | GrGGMGGsDrGGFNk | | P35637 | S273-p | Phosphorylation | GGPrDQGsRHDsEQD | | P35637 | S277-p | Phosphorylation | DQGsRHDsEQDNSDN | | P35637 | T286-p | Phosphorylation | QDNSDNNtIFVQGLG | | P35637 | T317-p | Phosphorylation | IIKTNKktGQPMINL | | P35637 | Y325-p | Phosphorylation | GQPMINLytDRETGk | | P35637 | T326-p | Phosphorylation | QPMINLytDRETGkL | | P35637 | S340-p | Phosphorylation | LkGEATVsFDDPPsA | | P35637 | S346-p | Phosphorylation | VsFDDPPsAkAAIDW | | P35637 | S360-p | Phosphorylation | WFdGkEFsGNPIkVS | | P35637 | Y397-p | Phosphorylation | GPMGrGGyGGGGSGG | | P35637 | S439-p | Phosphorylation | TCENMNFsWRNECNQ | | P35637 | S462-p | Phosphorylation | PGGGPGGsHMGGNyG | | P35637 | Y468-p | Phosphorylation | GsHMGGNyGDDRrGG | | P35637 | Y526-p | Phosphorylation | QDRRERPy_______ | | P35637 | K264-ub | Ubiquitination | sDrGGFNkFGGPrDQ | | P35637 | K316-ub | Ubiquitination | GIIKTNKktGQPMIN | | P35637 | K334-ub | Ubiquitination | DRETGkLkGEATVsF | | P35637 | K348-ub | Ubiquitination | FDDPPsAkAAIDWFd | | P35637 | K357-ub | Ubiquitination | AIDWFdGkEFsGNPI | | P35637 | K365-ub | Ubiquitination | EFsGNPIkVSFATrr | | P35637 | K448-ub | Ubiquitination | RNECNQCkAPKPDGP | |
| PTM - dbPTM | | UniProt ID | Position | Code | Type | Resources | References |
|---|
| P35637 | 216 | R | Methylation | Swiss-Prot 1010711 | 15782174 | | P35637 | 218 | R | Methylation | Swiss-Prot 1010711 | 15782174 | | P35637 | 277 | S | Phosphorylation | Swiss-Prot 1010711 | 19690332 | | P35637 | 286 | T | Phosphorylation | Swiss-Prot 1010711 | 19690332 | | P35637 | 346 | S | Phosphorylation | Swiss-Prot 1010711 | 19690332 | | P35637 | 257 | S | Phosphorylation | PhosphoELM.10011 | 10913197 | | P35637 | 216 | R | Methylation | Phosphositeplus.1010730 | 15782174 | | P35637 | 355 | D | Caspase | Phosphositeplus.1010730 | 18722006 | | P35637 | 316 | K | Ubiquitylation | Phosphositeplus.1010730 | 21890473;21906983 | | P35637 | 365 | K | Ubiquitylation | Phosphositeplus.1010730 | 21890473 | | P35637 | 216 | R | Methylation | Phosphositeplus.1010730 | 15782174 | | P35637 | 218 | R | Methylation | Phosphositeplus.1010730 | 15782174 | | P35637 | 131 | S | Phosphorylation | Phosphositeplus.1010730 | 18620545 | | P35637 | 221 | S | Phosphorylation | Phosphositeplus.1010730 | 21406692 | | P35637 | 257 | S | Phosphorylation | Phosphositeplus.1010730 | 10913197 | | P35637 | 26 | S | Phosphorylation | Phosphositeplus.1010730 | 18620545;22579282 | | P35637 | 277 | S | Phosphorylation | Phosphositeplus.1010730 | 19690332 | | P35637 | 42 | S | Phosphorylation | Phosphositeplus.1010730 | 18620545;22579282 | | P35637 | 462 | S | Phosphorylation | Phosphositeplus.1010730 | 20393185 | | P35637 | 61 | S | Phosphorylation | Phosphositeplus.1010730 | 18620545;22579282 | | P35637 | 84 | S | Phosphorylation | Phosphositeplus.1010730 | 18620545;22579282 | | P35637 | 286 | T | Phosphorylation | Phosphositeplus.1010730 | 19690332;21659604 | | P35637 | 468 | Y | Phosphorylation | Phosphositeplus.1010730 | 20007894 | | P35637 | 216 | R | Methylation | HPRD 9.0 | 15782174 | | P35637 | 218 | R | Methylation | HPRD 9.0 | 15782174 | | P35637 | 244 | R | Methylation | HPRD 9.0 | 15782174 | | P35637 | 386 | R | Methylation | HPRD 9.0 | 15782174 | | P35637 | 388 | R | Methylation | HPRD 9.0 | 15782174 | | P35637 | 487 | R | Methylation | HPRD 9.0 | 15782174 | | P35637 | 277 | S | Phosphorylation | HPRD 9.0 | 18452278 | | P35637 | 286 | T | Phosphorylation | HPRD 9.0 | 18452278 | | P35637 | 317 | T | Phosphorylation | HPRD 9.0 | 19651622,20068231 | | P35637 | 326 | T | Phosphorylation | HPRD 9.0 | 19651622 | | P35637 | 304 | Y | Phosphorylation | HPRD 9.0 | 20068231 | | P35637 | 325 | Y | Phosphorylation | HPRD 9.0 | 19651622 | | P35637 | 216 | R | Methylation | MeMo 2.0 | 15782174 | | P35637 | 218 | R | Methylation | MeMo 2.0 | 15782174 | | P35637 | 216 | R | Methylation | SysPTM 1.1 | 15782174 | | P35637 | 218 | R | Methylation | SysPTM 1.1 | 15782174 | |
| PTM - HPRD | | Symbol | Position | Code | Type | References |
|---|
| FUS | 216 | R | Methylation | 15782174 | | FUS | 218 | R | Methylation | 15782174 | | FUS | 244 | R | Methylation | 15782174 | | FUS | 277 | S | Phosphorylation | 18452278 | | FUS | 286 | T | Phosphorylation | 18452278 | | FUS | 304 | Y | Phosphorylation | 20068231 | | FUS | 317 | T | Phosphorylation | 19651622,20068231 | | FUS | 325 | Y | Phosphorylation | 19651622 | | FUS | 326 | T | Phosphorylation | 19651622 | | FUS | 386 | R | Methylation | 15782174 | | FUS | 388 | R | Methylation | 15782174 | | FUS | 487 | R | Methylation | 15782174 | |
| PTM - Phospho.ELM | | UniProt | Position | Code | PMIDs | Kinase | Source | Type |
|---|
| P35637 | 257 | S | 10913197 | PKC_beta | LTP | Phosphorylation | |
| PTM - UniProt | | UniProt ID | Position | Type | PMIDs |
|---|
| P35637 | 216 | Asymmetric dimethylarginine; alternate | 24129315 | | P35637 | 216 | Omega-N-methylarginine; alternate | 24129315 | | P35637 | 218 | Asymmetric dimethylarginine; alternate | 24129315 | | P35637 | 218 | Omega-N-methylarginine; alternate | 24129315 | | P35637 | 221 | Phosphoserine | 21406692 | | P35637 | 242 | Asymmetric dimethylarginine | 12964758 | | P35637 | 244 | Asymmetric dimethylarginine | 12964758 | | P35637 | 248 | Asymmetric dimethylarginine | 12964758 | | P35637 | 251 | Asymmetric dimethylarginine | 12964758 | | P35637 | 259 | Asymmetric dimethylarginine | 12964758 | | P35637 | 277 | Phosphoserine | 19690332 | | P35637 | 286 | Phosphothreonine | 19690332 | | P35637 | 340 | Phosphoserine | 23186163 | | P35637 | 377 | Asymmetric dimethylarginine | 12964758 | | P35637 | 383 | Asymmetric dimethylarginine | 12964758 | | P35637 | 386 | Asymmetric dimethylarginine | 12964758 | | P35637 | 388 | Asymmetric dimethylarginine | 12964758 | | P35637 | 394 | Asymmetric dimethylarginine | 12964758 | | P35637 | 407 | Asymmetric dimethylarginine; alternate | 12964758 | | P35637 | 473 | Asymmetric dimethylarginine | 12964758 | | P35637 | 476 | Asymmetric dimethylarginine | 12964758 | | P35637 | 481 | Asymmetric dimethylarginine | 12964758 | | P35637 | 485 | Asymmetric dimethylarginine | 12964758 | | P35637 | 487 | Asymmetric dimethylarginine | 12964758 | | P35637 | 491 | Asymmetric dimethylarginine | 12964758 | | P35637 | 495 | Asymmetric dimethylarginine | 12964758 | | P35637 | 498 | Asymmetric dimethylarginine | 12964758 | | P35637 | 503 | Asymmetric dimethylarginine; alternate | 12964758 | | P35637 | 503 | Omega-N-methylarginine; alternate | 24129315 | |
| PTM - PHOSIDA | | Symbol | Accession | Code | Position | Surrounding Sequence | Type |
|---|
| FUS | IPI00221354 | S | 256 | RGGMGGpSDRGGFN | phosphorylation | | FUS | IPI00221354 | T | 316 | IKTNKKpTGQPMIN | phosphorylation | |
| PTM - BioGRID | | Entrez Gene | BioGRID ID | Position | Code | Type | PMIDs |
|---|
| 2521 | 108797 | - | K | Ubiquitination | 22178446 | | 2521 | 108797 | - | K | Sumoylation | 21693764 | | 2521 | 108797 | - | K | Ubiquitination | 21139048 | | 2521 | 108797 | - | K | Ubiquitination | 21890473 | | 2521 | 108797 | - | K | Ubiquitination | 21906983 | | 2521 | 108797 | - | K | Ubiquitination | 22053931 | | 2521 | 108797 | - | K | FAT10ylation | 22797925 | | 2521 | 108797 | - | K | Ubiquitination | 23000965 | | 2521 | 108797 | - | K | FAT10ylation | 23862649 | | 2521 | 108797 | - | K | Ubiquitination | 24816145 | |
| PTM - mUbiSiDa | | Gene Name | Species | Ubiquitination Site | Ubiquitination Sequence | Evidence PMID |
|---|
| FUS | Homo sapiens (Human) | 365; 348 | "365,FSGNPIKVSFATR; 348,DDPPSAKAAIDWF" | 365:22053931; 348:22053931 | | FUS | Homo sapiens (Human) | 364 | "364,FSGNPIKVSFATR" | 364:21906983 | | FUS | Homo sapiens (Human) | 349; 317 | "349,DDPPSAKAAIDWF; 317,IIKTNKKTGQPMI" | 349:21906983; 317:21906983 | | FUS | Homo sapiens (Human) | 92 | "92,FSGNPIKVSFATR" | 92:21890473 | | FUS | Homo sapiens (Human) | 294; 245 | "294,FSGNPIKVSFATR; 245,IIKTNKKTGQPMI" | 294:21890473; 245:21890473 | | FUS | Homo sapiens (Human) | 368; 351; 319 | "368,FSGNPIKVSFATR; 351,DDPPSAKAAIDWF; 319,IIKTNKKTGQPMI" | "368:21890473; 351:21906983; 319:21890473,21906983" | | FUS | Homo sapiens (Human) | 364; 315; 347 | "364,FSGNPIKVSFATR; 315,IIKTNKKTGQPMI; 347,DDPPSAKAAIDWF" | "364:21890473,22053931; 315:21890473,21906983; 347:21906983,22053931" | | FUS | Homo sapiens (Human) | 368; 319 | "368,FSGNPIKVSFATR; 319,IIKTNKKTGQPMI" | 368:21890473; 319:21890473 | |