PTM - CPLM Gene Name UniProt ID Type Position Code ZC3HC1; NIPA; HSPC216 Q86WB0 Ubiquitination 485 K ZC3HC1; NIPA; HSPC216 Q86WB0 Ubiquitination 75 K ZC3HC1; NIPA; HSPC216 Q86WB0 Ubiquitination 31 K ZC3HC1; NIPA; HSPC216 Q86WB0 Ubiquitination 89 K ZC3HC1; NIPA; HSPC216 Q86WB0 Ubiquitination 93 K

PTM - dbPAF Gene Name UniProt ID Position Type Species ZC3HC1; NIPA; HSPC216 Q86WB0 105 Y Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 109 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 137 Y Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 161 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 163 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 24 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 28 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 301 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 303 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 321 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 329 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 333 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 335 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 338 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 344 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 350 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 352 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 354 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 357 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 358 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 359 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 370 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 372 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 373 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 381 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 384 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 387 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 394 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 395 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 407 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 408 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 409 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 410 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 411 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 413 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 414 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 415 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 417 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 471 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 472 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 477 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 479 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 481 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 483 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 486 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 52 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 53 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 55 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 56 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 58 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 62 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 84 T Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 87 S Homo sapiens(Human) ZC3HC1; NIPA; HSPC216 Q86WB0 98 S Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type ZC3HC1; NIPA; HSPC216 rs11556924 CGT->CAT R->H 359 S TRSWDSSSPVDRPEP 359 Phosphorylation TypeIII- ZC3HC1; NIPA; HSPC216 rs11556924 CGT->CAT R->H 370 S RPEPEAASPTTRTRP 370 Phosphorylation TypeIII- ZC3HC1; NIPA; HSPC216 rs13311752 GCT->GAT A->D 370 S RPEPEAASPTTRTRP 370 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q86WB0 R363-m1 Methylation DsssPVDrPEPEAAs Q86WB0 S24-p Phosphorylation NWGAVVRsPEGtPQK Q86WB0 T28-p Phosphorylation VVRsPEGtPQKIRQL Q86WB0 T52-p Phosphorylation GGVDAKDtsATsQsV Q86WB0 S53-p Phosphorylation GVDAKDtsATsQsVN Q86WB0 S56-p Phosphorylation AKDtsATsQsVNGsP Q86WB0 S58-p Phosphorylation DtsATsQsVNGsPQA Q86WB0 S62-p Phosphorylation TsQsVNGsPQAEQPS Q86WB0 T84-p Phosphorylation AFFSRVEtFSsLKWA Q86WB0 S87-p Phosphorylation SRVEtFSsLKWAGkP Q86WB0 S98-p Phosphorylation AGkPFELsPLVCAKY Q86WB0 S161-p Phosphorylation KFCFWPDsPsPDRFG Q86WB0 S163-p Phosphorylation CFWPDsPsPDRFGML Q86WB0 S321-p Phosphorylation RLPLVPEsPRRMMTR Q86WB0 S329-p Phosphorylation PRRMMTRsQDAtFsP Q86WB0 T333-p Phosphorylation MTRsQDAtFsPGsEQ Q86WB0 S335-p Phosphorylation RsQDAtFsPGsEQAE Q86WB0 S338-p Phosphorylation DAtFsPGsEQAEKsP Q86WB0 S344-p Phosphorylation GsEQAEKsPGPIVsR Q86WB0 S350-p Phosphorylation KsPGPIVsRtRsWDs Q86WB0 T352-p Phosphorylation PGPIVsRtRsWDsss Q86WB0 S354-p Phosphorylation PIVsRtRsWDsssPV Q86WB0 S357-p Phosphorylation sRtRsWDsssPVDrP Q86WB0 S358-p Phosphorylation RtRsWDsssPVDrPE Q86WB0 S359-p Phosphorylation tRsWDsssPVDrPEP Q86WB0 S370-p Phosphorylation rPEPEAAsPttRTRP Q86WB0 T372-p Phosphorylation EPEAAsPttRTRPVT Q86WB0 T373-p Phosphorylation PEAAsPttRTRPVTR Q86WB0 S381-p Phosphorylation RTRPVTRsMGtGDtP Q86WB0 T384-p Phosphorylation PVTRsMGtGDtPGLE Q86WB0 T387-p Phosphorylation RsMGtGDtPGLEVPs Q86WB0 S394-p Phosphorylation tPGLEVPssPLRKAK Q86WB0 S395-p Phosphorylation PGLEVPssPLRKAKR Q86WB0 S407-p Phosphorylation AKRARLCsssssDts Q86WB0 S408-p Phosphorylation KRARLCsssssDtss Q86WB0 S409-p Phosphorylation RARLCsssssDtssR Q86WB0 S410-p Phosphorylation ARLCsssssDtssRs Q86WB0 S411-p Phosphorylation RLCsssssDtssRsF Q86WB0 T413-p Phosphorylation CsssssDtssRsFFD Q86WB0 S414-p Phosphorylation sssssDtssRsFFDP Q86WB0 S415-p Phosphorylation ssssDtssRsFFDPT Q86WB0 S417-p Phosphorylation ssDtssRsFFDPTSQ Q86WB0 S471-p Phosphorylation ILLAHKQssQPAEtD Q86WB0 S472-p Phosphorylation LLAHKQssQPAEtDs Q86WB0 T477-p Phosphorylation QssQPAEtDsMsLsE Q86WB0 S479-p Phosphorylation sQPAEtDsMsLsEks Q86WB0 S481-p Phosphorylation PAEtDsMsLsEksRK Q86WB0 S483-p Phosphorylation EtDsMsLsEksRKVF Q86WB0 S486-p Phosphorylation sMsLsEksRKVFRIF Q86WB0 K75-ub Ubiquitination PSLESTSkEAFFSRV Q86WB0 K93-ub Ubiquitination SsLKWAGkPFELsPL Q86WB0 K485-ub Ubiquitination DsMsLsEksRKVFRI

PTM - dbPTM UniProt ID Position Code Type Resources References Q86WB0 2 A Acetylation Swiss-Prot 1010711 19413330 Q86WB0 24 S Phosphorylation Swiss-Prot 1010711 16964243;17081983;18187866;18669648 Q86WB0 28 T Phosphorylation Swiss-Prot 1010711 16964243;17081983;18669648 Q86WB0 58 S Phosphorylation Swiss-Prot 1010711 19413330;19690332 Q86WB0 62 S Phosphorylation Swiss-Prot 1010711 19413330;19690332 Q86WB0 84 T Phosphorylation Swiss-Prot 1010711 18187866 Q86WB0 321 S Phosphorylation Swiss-Prot 1010711 16964243;17081983;18220336;18669648;18691976;19413330;19690332 Q86WB0 333 T Phosphorylation Swiss-Prot 1010711 18669648 Q86WB0 335 S Phosphorylation Swiss-Prot 1010711 18669648;19413330;19690332 Q86WB0 338 S Phosphorylation Swiss-Prot 1010711 18669648;19369195;19413330;19690332 Q86WB0 344 S Phosphorylation Swiss-Prot 1010711 18669648;19413330;19690332 Q86WB0 354 S Phosphorylation Swiss-Prot 1010711 12748172;17081983;18669648;19690332 Q86WB0 357 S Phosphorylation Swiss-Prot 1010711 18669648 Q86WB0 359 S Phosphorylation Swiss-Prot 1010711 19690332 Q86WB0 370 S Phosphorylation Swiss-Prot 1010711 18669648;19007248;19690332 Q86WB0 384 T Phosphorylation Swiss-Prot 1010711 18669648 Q86WB0 387 T Phosphorylation Swiss-Prot 1010711 18669648;19413330;19690332 Q86WB0 394 S Phosphorylation Swiss-Prot 1010711 18669648 Q86WB0 395 S Phosphorylation Swiss-Prot 1010711 18220336;18669648;18691976;19413330;19690332 Q86WB0 24 S Phosphorylation PhosphoELM.10011 18669648;16964243;17081983 Q86WB0 58 S Phosphorylation PhosphoELM.10011 18669648 Q86WB0 62 S Phosphorylation PhosphoELM.10011 15302935 Q86WB0 321 S Phosphorylation PhosphoELM.10011 18669648;18220336;16964243;17081983 Q86WB0 335 S Phosphorylation PhosphoELM.10011 18669648 Q86WB0 338 S Phosphorylation PhosphoELM.10011 18669648 Q86WB0 344 S Phosphorylation PhosphoELM.10011 18669648 Q86WB0 350 S Phosphorylation PhosphoELM.10011 18669648 Q86WB0 354 S Phosphorylation PhosphoELM.10011 18669648;18220336;17081983;15302935 Q86WB0 357 S Phosphorylation PhosphoELM.10011 18669648 Q86WB0 359 S Phosphorylation PhosphoELM.10011 18669648 Q86WB0 370 S Phosphorylation PhosphoELM.10011 18669648;18220336 Q86WB0 394 S Phosphorylation PhosphoELM.10011 18669648 Q86WB0 395 S Phosphorylation PhosphoELM.10011 18669648;18220336 Q86WB0 28 T Phosphorylation PhosphoELM.10011 18669648;16964243;17081983 Q86WB0 333 T Phosphorylation PhosphoELM.10011 18669648 Q86WB0 352 T Phosphorylation PhosphoELM.10011 18669648 Q86WB0 384 T Phosphorylation PhosphoELM.10011 18669648 Q86WB0 387 T Phosphorylation PhosphoELM.10011 18669648 Q86WB0 105 Y Phosphorylation PhosphoELM.10011 12748172 Q86WB0 137 Y Phosphorylation PhosphoELM.10011 12748172 Q86WB0 485 K Ubiquitylation Phosphositeplus.1010730 21906983 Q86WB0 75 K Ubiquitylation Phosphositeplus.1010730 21906983 Q86WB0 24 S Phosphorylation Phosphositeplus.1010730 16964243;17081983;18187866;18669648;19276368;19664995;20068231;20363803;21406692;22115753 Q86WB0 321 S Phosphorylation Phosphositeplus.1010730 16964243;17081983;18220336;18669648;18691976;18707149;19276368;19664994;19664995;19690332;20068231;20363803;20815410;21406692;21659604;22115753 Q86WB0 329 S Phosphorylation Phosphositeplus.1010730 16964243;19691289;21406692 Q86WB0 335 S Phosphorylation Phosphositeplus.1010730 16964243;18669648;19362540;19664994;19664995;19690332;19691289;20068231;20363803;20562096;21406692;22115753 Q86WB0 338 S Phosphorylation Phosphositeplus.1010730 16964243;18669648;19276368;19664995;19690332;20562096;21406692 Q86WB0 344 S Phosphorylation Phosphositeplus.1010730 16964243;18669648;18707149;19276368;19415658;19664995;19690332;19691289;20068231;20164059;20230923;20363803;20562096;20815410;21406692 Q86WB0 350 S Phosphorylation Phosphositeplus.1010730 16964243;18669648 Q86WB0 354 S Phosphorylation Phosphositeplus.1010730 12748172;16009132;16964243;17389604;18220336;18669648;19276368;19690332;20068231;20363803;21406692 Q86WB0 358 S Phosphorylation Phosphositeplus.1010730 19276368 Q86WB0 359 S Phosphorylation Phosphositeplus.1010730 16964243;17389604;18669648;19276368;19690332 Q86WB0 370 S Phosphorylation Phosphositeplus.1010730 16964243;17389604;18220336;18669648;19276368;19664994;19664995;19690332 Q86WB0 381 S Phosphorylation Phosphositeplus.1010730 20363803 Q86WB0 394 S Phosphorylation Phosphositeplus.1010730 18187866;18847512;19276368;19664995;20562096 Q86WB0 395 S Phosphorylation Phosphositeplus.1010730 17389604;18187866;18220336;18234856;18669648;18691976;18847512;19276368;19415658;19664995;19690332;20044836;20068231;20166139;20562096;20815410;21406692;21659604 Q86WB0 407 S Phosphorylation Phosphositeplus.1010730 16964243;19664995;20363803;20736484;21406692 Q86WB0 408 S Phosphorylation Phosphositeplus.1010730 20736484 Q86WB0 409 S Phosphorylation Phosphositeplus.1010730 20736484 Q86WB0 410 S Phosphorylation Phosphositeplus.1010730 20363803;20736484 Q86WB0 411 S Phosphorylation Phosphositeplus.1010730 20736484 Q86WB0 414 S Phosphorylation Phosphositeplus.1010730 20736484 Q86WB0 471 S Phosphorylation Phosphositeplus.1010730 20068231 Q86WB0 472 S Phosphorylation Phosphositeplus.1010730 20068231 Q86WB0 479 S Phosphorylation Phosphositeplus.1010730 20044836;20068231 Q86WB0 481 S Phosphorylation Phosphositeplus.1010730 20068231 Q86WB0 483 S Phosphorylation Phosphositeplus.1010730 20068231 Q86WB0 486 S Phosphorylation Phosphositeplus.1010730 20044836 Q86WB0 58 S Phosphorylation Phosphositeplus.1010730 18669648;19276368;19690332;22115753 Q86WB0 62 S Phosphorylation Phosphositeplus.1010730 15302935;19276368;19664994;19664995;19690332;20068231;21406692;22115753 Q86WB0 28 T Phosphorylation Phosphositeplus.1010730 16964243;17081983;18669648;19276368 Q86WB0 333 T Phosphorylation Phosphositeplus.1010730 18669648 Q86WB0 352 T Phosphorylation Phosphositeplus.1010730 19276368 Q86WB0 384 T Phosphorylation Phosphositeplus.1010730 18187866;18669648;20815410 Q86WB0 387 T Phosphorylation Phosphositeplus.1010730 18669648;19276368;19690332;20044836 Q86WB0 413 T Phosphorylation Phosphositeplus.1010730 20736484 Q86WB0 477 T Phosphorylation Phosphositeplus.1010730 20068231 Q86WB0 24 S Phosphorylation HPRD 9.0 17322306,18669648,19664995,19651622,18767875,20068231 Q86WB0 58 S Phosphorylation HPRD 9.0 18669648,19413330,18452278,20068231 Q86WB0 62 S Phosphorylation HPRD 9.0 15302935,15345747,19413330,19664995,19651622,19691289,19664994,18452278,20068231 Q86WB0 321 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,19664995,19651622,19664994,18691976,20068231 Q86WB0 329 S Phosphorylation HPRD 9.0 19691289,16964243 Q86WB0 335 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,19664995,19651622,19691289,19664994,16964243,20068231 Q86WB0 338 S Phosphorylation HPRD 9.0 18669648,19413330,19664995,18767875,20230923 Q86WB0 344 S Phosphorylation HPRD 9.0 18669648,19413330,19415658,19664995,19651622,19691289,18452278,16964243,20230923,20068231 Q86WB0 350 S Phosphorylation HPRD 9.0 18669648 Q86WB0 354 S Phosphorylation HPRD 9.0 12748172 Q86WB0 354 S Phosphorylation HPRD 9.0 12748172,18669648,19651622,18452278,20068231 Q86WB0 357 S Phosphorylation HPRD 9.0 18669648,18452278 Q86WB0 358 S Phosphorylation HPRD 9.0 19651622,18452278 Q86WB0 359 S Phosphorylation HPRD 9.0 18669648,19651622,18452278,20068231 Q86WB0 370 S Phosphorylation HPRD 9.0 18669648,19007248,19664995,19651622,19664994,16964243,18452278,20068231 Q86WB0 394 S Phosphorylation HPRD 9.0 18669648,19664995,20068231 Q86WB0 395 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,19415658,19664995,19651622,18452278,18691976,20166139,20068231 Q86WB0 407 S Phosphorylation HPRD 9.0 19664995,18212344,20068231 Q86WB0 471 S Phosphorylation HPRD 9.0 20068231 Q86WB0 472 S Phosphorylation HPRD 9.0 20068231 Q86WB0 479 S Phosphorylation HPRD 9.0 20068231 Q86WB0 481 S Phosphorylation HPRD 9.0 20068231 Q86WB0 483 S Phosphorylation HPRD 9.0 20068231 Q86WB0 28 T Phosphorylation HPRD 9.0 17322306,18669648,19413330,16964243,20068231 Q86WB0 333 T Phosphorylation HPRD 9.0 18669648 Q86WB0 352 T Phosphorylation HPRD 9.0 18669648,20068231 Q86WB0 372 T Phosphorylation HPRD 9.0 18452278 Q86WB0 373 T Phosphorylation HPRD 9.0 20068231 Q86WB0 384 T Phosphorylation HPRD 9.0 18669648 Q86WB0 387 T Phosphorylation HPRD 9.0 18669648,19413330 Q86WB0 477 T Phosphorylation HPRD 9.0 20068231 Q86WB0 105 Y Phosphorylation HPRD 9.0 12748172 Q86WB0 137 Y Phosphorylation HPRD 9.0 12748172 Q86WB0 24 S Phosphorylation SysPTM 1.1 18669648;16964243 Q86WB0 321 S Phosphorylation SysPTM 1.1 18669648;16964243;18707149 Q86WB0 335 S Phosphorylation SysPTM 1.1 18669648 Q86WB0 338 S Phosphorylation SysPTM 1.1 18669648 Q86WB0 344 S Phosphorylation SysPTM 1.1 18669648;18707149 Q86WB0 354 S Phosphorylation SysPTM 1.1 16964243;18669648 Q86WB0 357 S Phosphorylation SysPTM 1.1 18669648 Q86WB0 359 S Phosphorylation SysPTM 1.1 16964243 Q86WB0 370 S Phosphorylation SysPTM 1.1 16964243;18669648 Q86WB0 394 S Phosphorylation SysPTM 1.1 18669648 Q86WB0 395 S Phosphorylation SysPTM 1.1 18669648 Q86WB0 407 S Phosphorylation SysPTM 1.1 18212344;16964243 Q86WB0 321 S Phosphorylation SysPTM 1.1 18691976 Q86WB0 395 S Phosphorylation SysPTM 1.1 17081983;18691976 Q86WB0 28 T Phosphorylation SysPTM 1.1 18669648;16964243 Q86WB0 333 T Phosphorylation SysPTM 1.1 18669648;17081983 Q86WB0 384 T Phosphorylation SysPTM 1.1 18669648 Q86WB0 387 T Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References ZC3HC1 105 Y Phosphorylation 12748172 ZC3HC1 137 Y Phosphorylation 12748172 ZC3HC1 24 S Phosphorylation 17322306,18669648,19664995,19651622,18767875,20068231 ZC3HC1 28 T Phosphorylation 17322306,18669648,19413330,16964243,20068231 ZC3HC1 321 S Phosphorylation 17322306,18669648,19413330,19664995,19651622,19664994,18691976,20068231 ZC3HC1 329 S Phosphorylation 19691289,16964243 ZC3HC1 333 T Phosphorylation 18669648 ZC3HC1 335 S Phosphorylation 17322306,18669648,19413330,19664995,19651622,19691289,19664994,16964243,20068231 ZC3HC1 338 S Phosphorylation 18669648,19413330,19664995,18767875,20230923 ZC3HC1 344 S Phosphorylation 18669648,19413330,19415658,19664995,19651622,19691289,18452278,16964243,20230923,20068231 ZC3HC1 350 S Phosphorylation 18669648 ZC3HC1 352 T Phosphorylation 18669648,20068231 ZC3HC1 354 S Phosphorylation 12748172 ZC3HC1 354 S Phosphorylation 12748172,18669648,19651622,18452278,20068231 ZC3HC1 357 S Phosphorylation 18669648,18452278 ZC3HC1 358 S Phosphorylation 19651622,18452278 ZC3HC1 359 S Phosphorylation 18669648,19651622,18452278,20068231 ZC3HC1 370 S Phosphorylation 18669648,19007248,19664995,19651622,19664994,16964243,18452278,20068231 ZC3HC1 372 T Phosphorylation 18452278 ZC3HC1 373 T Phosphorylation 20068231 ZC3HC1 384 T Phosphorylation 18669648 ZC3HC1 387 T Phosphorylation 18669648,19413330 ZC3HC1 394 S Phosphorylation 18669648,19664995,20068231 ZC3HC1 395 S Phosphorylation 17322306,18669648,19413330,19415658,19664995,19651622,18452278,18691976,20166139,20068231 ZC3HC1 407 S Phosphorylation 19664995,18212344,20068231 ZC3HC1 471 S Phosphorylation 20068231 ZC3HC1 472 S Phosphorylation 20068231 ZC3HC1 477 T Phosphorylation 20068231 ZC3HC1 479 S Phosphorylation 20068231 ZC3HC1 481 S Phosphorylation 20068231 ZC3HC1 483 S Phosphorylation 20068231 ZC3HC1 58 S Phosphorylation 18669648,19413330,18452278,20068231 ZC3HC1 62 S Phosphorylation 15302935,15345747,19413330,19664995,19651622,19691289,19664994,18452278,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q86WB0 137 Y 12748172 ALK LTP Phosphorylation Q86WB0 395 S 18669648 HTP Phosphorylation Q86WB0 395 S 18220336 HTP Phosphorylation Q86WB0 105 Y 12748172 ALK LTP Phosphorylation Q86WB0 394 S 18669648 HTP Phosphorylation Q86WB0 352 T 18669648 HTP Phosphorylation Q86WB0 359 S 18669648 HTP Phosphorylation Q86WB0 357 S 18669648 HTP Phosphorylation Q86WB0 321 S 18669648 HTP Phosphorylation Q86WB0 321 S 18220336 HTP Phosphorylation Q86WB0 321 S 16964243 HTP Phosphorylation Q86WB0 321 S 17081983 HTP Phosphorylation Q86WB0 387 T 18669648 HTP Phosphorylation Q86WB0 354 S 18669648 HTP Phosphorylation Q86WB0 354 S 18220336 HTP Phosphorylation Q86WB0 354 S 17081983 HTP Phosphorylation Q86WB0 354 S 15302935 HTP Phosphorylation Q86WB0 333 T 18669648 HTP Phosphorylation Q86WB0 344 S 18669648 HTP Phosphorylation Q86WB0 62 S 15302935 HTP Phosphorylation Q86WB0 335 S 18669648 HTP Phosphorylation Q86WB0 338 S 18669648 HTP Phosphorylation Q86WB0 24 S 18669648 HTP Phosphorylation Q86WB0 24 S 16964243 HTP Phosphorylation Q86WB0 24 S 17081983 HTP Phosphorylation Q86WB0 384 T 18669648 HTP Phosphorylation Q86WB0 58 S 18669648 HTP Phosphorylation Q86WB0 370 S 18669648 HTP Phosphorylation Q86WB0 370 S 18220336 HTP Phosphorylation Q86WB0 28 T 18669648 HTP Phosphorylation Q86WB0 28 T 16964243 HTP Phosphorylation Q86WB0 28 T 17081983 HTP Phosphorylation Q86WB0 350 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q86WB0 2 N-acetylalanine 19413330;22223895 Q86WB0 24 Phosphoserine 16964243;17081983;20068231;21406692;23186163 Q86WB0 28 Phosphothreonine 16964243;17081983;23186163 Q86WB0 58 Phosphoserine 19690332;23186163 Q86WB0 62 Phosphoserine 19690332;21406692;23186163 Q86WB0 84 Phosphothreonine 23186163 Q86WB0 321 Phosphoserine 18220336;18691976;20068231;21406692;23186163;24275569 Q86WB0 329 Phosphoserine 21406692;23186163 Q86WB0 333 Phosphothreonine 18669648 Q86WB0 335 Phosphoserine 18669648;19690332;20068231;21406692;23186163 Q86WB0 338 Phosphoserine 18669648;19690332 Q86WB0 344 Phosphoserine 18669648;19690332;20068231;21406692;23186163;24275569 Q86WB0 354 Phosphoserine 18669648;19690332;21406692;23186163;24275569;12748172 Q86WB0 359 Phosphoserine 19690332 Q86WB0 370 Phosphoserine 18669648;19690332 Q86WB0 381 Phosphoserine 23186163 Q86WB0 384 Phosphothreonine 18669648 Q86WB0 387 Phosphothreonine 18669648;19690332;23186163 Q86WB0 395 Phosphoserine 18669648;19690332;23186163 Q86WB0 407 Phosphoserine 24275569 Q86WB0 483 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type ZC3HC1 IPI00301421 S 24 WGAVVRpSPEGTPQ phosphorylation ZC3HC1 IPI00301421 S 321 LPLVPEpSPRRMMT phosphorylation ZC3HC1 IPI00301421 S 335 SQDATFpSPGSEQA phosphorylation ZC3HC1 IPI00301421 S 344 SEQAEKpSPGPIVS phosphorylation ZC3HC1 IPI00301421 S 354 IVSRTRpSWDSSSP phosphorylation ZC3HC1 IPI00301421 S 394 PGLEVPpSSPLRKA phosphorylation ZC3HC1 IPI00301421 S 395 GLEVPSpSPLRKAK phosphorylation ZC3HC1 IPI00301421 S 62 SQSVNGpSPQAEQP phosphorylation ZC3HC1 IPI00301421 T 28 VRSPEGpTPQKIRQ phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 51530 119592 - K Ubiquitination 22205987 51530 119592 - K Ubiquitination 21139048 51530 119592 - K Ubiquitination 21906983 51530 119592 - K Ubiquitination 22505724 51530 119592 - K Ubiquitination 24816145

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID ZC3HC1 Homo sapiens (Human) 485; 75 "485,SMSLSEKSRKVFR; 75,SLESTSKEAFFSR" 485:21906983; 75:21906983 ZC3HC1 Homo sapiens (Human) 54; 464 "54,SLESTSKEAFFSR; 464,SMSLSEKSRKVFR" 54:21906983; 464:21906983 ZC3HC1 Homo sapiens (Human) 414; 75 "414,SMSLSEKSRKVFR; 75,SLESTSKEAFFSR" 414:21906983; 75:21906983