PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus DLG1 MARCH2 17980554 biogrid exp GP GP G G GP GP G G GP G GP G GP GP G GP GP P GP G GP GP GP G GP GP GP GP G ADRB2 MARCH2 23166351 biogrid exp GP G G G GP G G G GP G P GP GP G G GP G GP G GP GP G G GP GP GP GP G UBE2D1 MARCH2 14722266 biogrid exp GP G G G GP GP G G GP G GP GP GP GP G G GP P GP G GP GP G GP G GP GP GP G ELAVL1 MARCH2 19322201 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP G GP GP G CCDC155 MARCH2 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP P G GP GP P GP G P P P GP GP G GP GP G LDLRAD1 MARCH2 25416956 biogrid,intact exp P P P P P P P P CDC34 MARCH2 14722266 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G CFTR MARCH2 23818989 biogrid exp P P GP P P GP P GP P GP GP P FATE1 MARCH2 25416956 biogrid,intact exp G G G G G P G G GP G G G G G GP G GP UBE2H MARCH2 14722266 hprd,biogrid,bci exp GP GP G G GP GP G GP G G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G GOPC MARCH2 23818989 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G SYNE4 MARCH2 25416956 biogrid,intact exp P GP P GP G GP GP G GP GP GP P G GP GP P GP G GP GP GP GP GP P GP P G STX6 MARCH2 23818989,15689499, 21836163 hprd,biogrid,bci exp, ortho, pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP G GP GP GP G GP GP GP GP G VAMP4 MARCH2 ortho G GP G G G GP G GP GP G GP G G GP G GP GP GP G G GP GP GP GP G GP GP G UBC MARCH2 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G STX12 MARCH2 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP P GP G GP GP GP G GP G GP GP G MARCH3 MARCH2 ortho G G G G GP GP G G GP G GP G G G G GP GP GP G G GP GP GP GP GP GP GP G MARCH2 STX8 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G GPR124 MARCH2 25402006 pred G G G G G GP G GP G G GP GP G G G GP GP P G G G GP GP GP G GP G G LIN7A MARCH2 25402006 pred G G G G G G G G G G G G G G G G G G AZI2 MARCH2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G KIF1B MARCH2 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G MARCH2 BTRC 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP G GP GP G MARCH2 CACNG2 25402006 pred G G G G G G G G G G KCNA3 MARCH2 25402006 pred G G P G G P G GP PBK MARCH2 25402006 pred P G GP P P GP P P P P GP P P P P P GP P GP GP LRRC1 MARCH2 25402006 pred GP P GP G G GP G GP P GP G GP GP GP G GP GP GP P GP GP P G RFFL MARCH2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P P G GP GP GP GP GP GP GP GP G TGOLN2 MARCH2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G KIF13B MARCH2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP G GP G GP G GP GP G LIN7C MARCH2 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP G GP GP GP GP GP GP GP GP G KCNA5 MARCH2 25402006 pred P P P GP P G P P P P P P P P P P P P P P ARL1 MARCH2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G1 MARCH2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G KCNJ6 MARCH2 25402006 pred P P G P GP P P G P P P P P GP P GP G P P P P P P P P TJAP1 MARCH2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP P GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9P0N8 affinity chromatography technology 23166351 physical association X 2 Q9P0N8 imaging technique 23166351 colocalization X 2 A0A087WW00 Q9P0N8 pull down 14722266 direct interaction X 2 Q9P0N8 Q9HD26-3 affinity chromatography technology 23818989 physical association X 2 Q9P0N8 Q9HD26-3 affinity chromatography technology 23818989 physical association X 2 Q9P0N8 A0A024R730 affinity chromatography technology 23818989 physical association X 2 Q9P0N8 pull down 14722266 direct interaction X 2 Q9P0N8 Q8N205 two hybrid 25416956 direct interaction X 2 Q9P0N8 Q5T700 two hybrid 25416956 direct interaction X 2 O43752 Q9P0N8 affinity chromatography technology 23818989 physical association X 2 O43752 Q9P0N8 affinity chromatography technology 23818989 physical association X 2 Q9P0N8 A0A024R1Z1 pull down 14722266 direct interaction X 2 Q9P0N8 Q12959-4 affinity chromatography technology 17980554 physical association X 2 Q9P0N8 Q12959-4 affinity chromatography technology 17980554 physical association X 2 Q8N6L0 Q9P0N8 two hybrid 25416956 direct interaction X 2 Q969F0 Q9P0N8 two hybrid 25416956 direct interaction X 2 Q9P0N8 Q5T700 two hybrid prey pooling approach 25416956 physical association X 2 Q9P0N8 Q8N205 two hybrid prey pooling approach 25416956 physical association X 2 Q9P0N8 Q5T700 two hybrid array 25416956 physical association X 2 Q9P0N8 Q8N205 two hybrid array 25416956 physical association X 2 Q9P0N8 Q5T700 validated two hybrid 25416956 physical association X 2 Q9P0N8 Q8N205 validated two hybrid 25416956 physical association X 2 Q8N6L0 Q9P0N8 two hybrid prey pooling approach 25416956 physical association X 2 Q8N6L0 Q9P0N8 two hybrid array 25416956 physical association X 2 Q8N6L0 Q9P0N8 validated two hybrid 25416956 physical association X 2 Q969F0 Q9P0N8 two hybrid prey pooling approach 25416956 physical association X 2 Q969F0 Q9P0N8 two hybrid array 25416956 physical association X 2 Q969F0 Q9P0N8 validated two hybrid 25416956 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9P0N8 Q8N6L0 MARCH2 CCDC155 0.454 25416956 Q9P0N8 Q9BVX2 MARCH2 TMEM106C 0.236 unassigned1304 Q9P0N8 Q969F0 MARCH2 FATE1 0.583 25416956,unassigned1304 Q9P0N8 Q96BA8 MARCH2 CREB3L1 0.236 unassigned1304 Q9P0N8 P13236 MARCH2 CCL4 0.236 unassigned1304 Q9P0N8 P07550 MARCH2 ADRB2 0.309 23166351 Q9P0N8 Q5T700 MARCH2 LDLRAD1 0.583 25416956,unassigned1304 Q9P0N8 P51668 MARCH2 UBE2D1 0.309 14722266 Q9P0N8 P49427 MARCH2 CDC34 0.309 14722266 Q9P0N8 P13569 MARCH2 CFTR 0.21 23818989 Q9P0N8 P62256 MARCH2 UBE2H 0.309 14722266 Q9P0N8 Q12959 MARCH2 DLG1 0.376 17980554 Q9P0N8 Q8N205 MARCH2 SYNE4 0.454 25416956 Q9P0N8 Q9HD26 MARCH2 GOPC 0.376 23818989 Q9P0N8 O43752 MARCH2 STX6 0.376 23818989 Q9P0N8 Q15717 MARCH2 ELAVL1 0.126 19322201

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 LIN7A MARCH2 MI:0362 inference MI:0461 interaction database STX6 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database VAMP4 MARCH2 MI:0362 inference MI:0461 interaction database ADRB2 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database UBC MARCH2 MI:0362 inference MI:0461 interaction database CFTR MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database CDC34 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2H MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database DLG1 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database LDLRAD1 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database MARCH3 MARCH2 MI:0362 inference MI:0461 interaction database STX12 MARCH2 MI:0362 inference MI:0461 interaction database SYNE4 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database CCDC155 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database FATE1 MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database GOPC MARCH2 MI:0045 experimental interaction detection MI:0461 interaction database MARCH2 STX8 MI:0362 inference MI:0461 interaction database