PTM - CPLM Gene Name UniProt ID Type Position Code CDC34; UBCH3; UBE2R1 P49427 Ubiquitination 63 K CDC34; UBCH3; UBE2R1 P49427 Ubiquitination 11 K CDC34; UBCH3; UBE2R1 P49427 Ubiquitination 18 K CDC34; UBCH3; UBE2R1 P49427 Ubiquitination 193 K CDC34; UBCH3; UBE2R1 P49427 Ubiquitination 80 K

PTM - dbPAF Gene Name UniProt ID Position Type Species CDC34; UBCH3; UBE2R1 P49427 190 Y Homo sapiens(Human) CDC34; UBCH3; UBE2R1 P49427 203 S Homo sapiens(Human) CDC34; UBCH3; UBE2R1 P49427 222 S Homo sapiens(Human) CDC34; UBCH3; UBE2R1 P49427 231 S Homo sapiens(Human) CDC34; UBCH3; UBE2R1 P49427 233 T Homo sapiens(Human) CDC34; UBCH3; UBE2R1 P49427 236 S Homo sapiens(Human) CDC34; UBCH3; UBE2R1 P49427 68 Y Homo sapiens(Human) CDC34; UBCH3; UBE2R1 P49427 71 S Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type CDC34; UBCH3; UBE2R1 rs16990650 GAT->CAT D->H 222 S EVEEEADSCFGDDED 222 Phosphorylation: CK2_group TypeIII- CDC34; UBCH3; UBE2R1 rs16990650 GAT->CAT D->H 231 S FGDDEDDSGTEES** 231 Phosphorylation: CK2_group; CK2 alpha TypeIII- CDC34; UBCH3; UBE2R1 rs16990650 GAT->CAT D->H 233 T DDEDDSGTEES**** 233 Phosphorylation: CK2_group TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P49427 R166-m1 Methylation REYtDIIrKQVLGTK P49427 Y68-p Phosphorylation RLkFPIDyPYsPPAF P49427 S71-p Phosphorylation FPIDyPYsPPAFRFL P49427 T89-p Phosphorylation WHPNIYEtGDVCISI P49427 T162-p Phosphorylation KGKDREYtDIIrKQV P49427 Y190-p Phosphorylation VPTTLAEyCVkTKAP P49427 S203-p Phosphorylation APAPDEGsDLFYDDY P49427 S222-p Phosphorylation EVEEEADsCFGDDED P49427 S231-p Phosphorylation FGDDEDDsGtEEs__ P49427 T233-p Phosphorylation DDEDDsGtEEs____ P49427 S236-p Phosphorylation DDsGtEEs_______ P49427 K11-ub Ubiquitination PLVPSSQkALLLELk P49427 K18-ub Ubiquitination kALLLELkGLQEEPV P49427 K63-ub Ubiquitination GYFKARLkFPIDyPY P49427 K193-ub Ubiquitination TLAEyCVkTKAPAPD

PTM - dbPTM UniProt ID Position Code Type Resources References P49427 203 S Phosphorylation Swiss-Prot 1010711 11546811;17461777 P49427 222 S Phosphorylation Swiss-Prot 1010711 11546811;17461777 P49427 231 S Phosphorylation Swiss-Prot 1010711 11546811;12037680;17461777 P49427 233 T Phosphorylation Swiss-Prot 1010711 11546811 P49427 236 S Phosphorylation Swiss-Prot 1010711 11546811 P49427 203 S Phosphorylation PhosphoELM.10011 11546811 P49427 222 S Phosphorylation PhosphoELM.10011 11546811 P49427 236 S Phosphorylation PhosphoELM.10011 11546811 P49427 231 S Phosphorylation PhosphoELM.10011 12037680;11546811;12037680;11546811 P49427 233 T Phosphorylation PhosphoELM.10011 11546811 P49427 11 K Ubiquitylation Phosphositeplus.1010730 21890473 P49427 18 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 P49427 63 K Ubiquitylation Phosphositeplus.1010730 20639865;21890473 P49427 203 S Phosphorylation Phosphositeplus.1010730 11546811;16123592 P49427 222 S Phosphorylation Phosphositeplus.1010730 11546811;16123592 P49427 231 S Phosphorylation Phosphositeplus.1010730 11546811;16123592 P49427 236 S Phosphorylation Phosphositeplus.1010730 11546811;16123592 P49427 71 S Phosphorylation Phosphositeplus.1010730 20068231 P49427 233 T Phosphorylation Phosphositeplus.1010730 11546811;16123592 P49427 68 Y Phosphorylation Phosphositeplus.1010730 20068231 P49427 71 S Phosphorylation HPRD 9.0 20068231 P49427 68 Y Phosphorylation HPRD 9.0 20068231 P49427 203 S Phosphorylation (CSNK2B) HPRD 9.0 11546811 P49427 222 S Phosphorylation (CSNK2B) HPRD 9.0 11546811 P49427 231 S Phosphorylation (CSNK2B) HPRD 9.0 11546811 P49427 236 S Phosphorylation (CSNK2B) HPRD 9.0 11546811 P49427 233 T Phosphorylation (CSNK2B) HPRD 9.0 11546811

PTM - HPRD Symbol Position Code Type References CDC34 203 S Phosphorylation 11546811 CDC34 222 S Phosphorylation 11546811 CDC34 231 S Phosphorylation 11546811 CDC34 233 T Phosphorylation 11546811 CDC34 236 S Phosphorylation 11546811 CDC34 68 Y Phosphorylation 20068231 CDC34 71 S Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type P49427 233 T 11546811 CK2_group LTP Phosphorylation P49427 203 S 11546811 CK2_group LTP Phosphorylation P49427 236 S 11546811 CK2_group LTP Phosphorylation P49427 222 S 11546811 CK2_group LTP Phosphorylation P49427 231 S 12037680 CK2_group LTP Phosphorylation P49427 231 S 11546811 CK2_group LTP Phosphorylation P49427 231 S 12037680 CK2_alpha LTP Phosphorylation P49427 231 S 11546811 CK2_alpha LTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs P49427 203 Phosphoserine; by CK2 11546811;17461777 P49427 222 Phosphoserine; by CK2 11546811;17461777 P49427 231 Phosphoserine; by CK2 11546811;12037680;17461777 P49427 233 Phosphothreonine; by CK2 11546811 P49427 236 Phosphoserine; by CK2 11546811

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 997 107432 - K Ubiquitination 20378537 997 107432 - K Ubiquitination 20639865 997 107432 - K Ubiquitination 21963094 997 107432 - K Ubiquitination 21139048 997 107432 - K Ubiquitination 21890473 997 107432 - K Ubiquitination 21906983 997 107432 - K Sumoylation 19471022 997 107432 - K Ubiquitination 22053931 997 107432 - K Ubiquitination 23261596 997 107432 - K Ubiquitination 23000965 997 107432 - K Ubiquitination 24816145 997 107432 - K Ubiquitination 25147182

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID CDC34 Homo sapiens (Human) 18; 11; 63 "18,ALLLELKGLQEEP; 11,LVPSSQKALLLEL; 63,YFKARLKFPIDYP" "18:21890473,21906983,22053931; 11:21890473; 63:21890473,22053931"