PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus GBF1 FBXO7 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP GP GP G G GP G UBC FBXO7 16196087 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G SHFM1 FBXO7 24811749 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SIRT1 FBXO7 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PVRL3 FBXO7 26496610 biogrid,intact exp GP GP G P GP G GP GP G GP GP GP P G GP GP GP GP G GP GP GP GP GP GP GP G PSMB4 FBXO7 26186194 biogrid exp G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP G GP GP G PINK1 FBXO7 23933751 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PARK2 FBXO7 23933751 biogrid,intact exp P GP G P GP G GP GP G GP P P G P GP GP P G P GP GP GP P GP G PARP10 FBXO7 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G G G G GP G G GP G GP G GP G GP GP G G GP GP G PRMT1 FBXO7 26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP G G G GP GP GP GP GP G GP GP G PSMG2 FBXO7 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CRNKL1 FBXO7 26496610 biogrid,intact exp G G G G G GP G G GP G G G GP G G GP GP G G G G G GP G GP G GP GP G SRRT FBXO7 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G NSFL1C FBXO7 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G PSMB9 FBXO7 26186194 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G PANX1 FBXO7 26496610 biogrid,intact exp G GP G G GP GP G GP P G GP G GP G G P GP GP GP G GP G G GP GP G GP GP G COPS2 FBXO7 26186194 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G UBE2D2 FBXO7 10531035 biogrid exp GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G G GP GP G ESF1 FBXO7 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G HSPD1 FBXO7 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G COPS6 FBXO7 19615732,21145461 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G TSHR FBXO7 26186194 biogrid exp P P P P P P P P P P P P P P SEC24C FBXO7 21988832 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TCEB1 FBXO7 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMB7 FBXO7 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXO7 MAGED1 24947323 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDKN1B FBXO7 i2d,bci exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G XPO1 FBXO7 21378169 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G RBBP6 FBXO7 18624398 biogrid,intact exp GP G G G G GP G GP GP G GP GP GP G G GP GP G G G GP G GP G GP G GP GP G PDE3A FBXO7 26496610 biogrid,intact exp G GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G G G GP GP GP G G G G CCND1 FBXO7 i2d,bci exp GP GP G P GP G G GP G GP GP G G G GP GP G G G G G GP G GP G GP P G ZBTB48 FBXO7 26496610 biogrid,intact exp G GP G G GP P P GP GP GP G GP G G P GP G P G GP P G G G GP G ESPL1 FBXO7 26496610 biogrid,intact exp GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP P GP GP GP G GP GP G CDK6 FBXO7 18495667 biogrid,i2d,bci exp G GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP G G GP G GP GP G ELF4 FBXO7 16581786 hprd,bci exp GP GP G G G G GP GP GP GP G G GP GP P G GP GP P GP G GP GP G PSMA3 FBXO7 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G HPSE FBXO7 26496610 biogrid,intact exp GP GP G GP P P P P P P GP P P G P GP P GP P P P GP BCAT1 FBXO7 26186194 biogrid exp GP GP G G GP GP G G GP G GP G G G GP GP GP GP G GP GP GP G GP GP GP G COPS5 FBXO7 21145461 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PSME3 FBXO7 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PSMF1 FBXO7 25416956,18495667,26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G GP G G GP G G GP G GP GP G XPOT FBXO7 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP G G GP G CCND3 FBXO7 25402006 i2d,bci exp, pred G GP G G GP GP G G GP G G G GP GP G G GP G GP G GP G G G G G G GP G BIRC2 FBXO7 22212761,16510124, 25402006, 21836163 innatedb,hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP G GP GP G CUL1 FBXO7 10531035,15145941,18495667,26496610,16278047,21145461, 25402006, 21836163 innatedb,biogrid,intact,bci exp, pred GP G G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G FBXW2 FBXO7 26496610, 25402006, 16082366 biogrid,intact exp, pred G GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G G G GP GP GP G GP GP G SKP1 FBXO7 20596027,24947323,10531037,21378169,25416956,10531035,22632967,15145941,16278047,26496610, 25402006, 23023127, 21836163 innatedb,hprd,biogrid,i2d,intact,dip,bci exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G DLGAP5 FBXO7 15145941, 21836163 biogrid exp, pred G GP P G P P P GP P P GP P P GP RBX1 FBXO7 25402006, 21836163 i2d exp, pred G G G G G GP G GP G G G G GP G G G GP G GP G GP GP G G G G G GP G PSMA6 FBXO7 26496610, 25402006 biogrid,intact exp, pred P P P P P P P P P P P P P P P P P P P TRAF2 FBXO7 22212761,25029497, 25402006 biogrid exp, pred P P P P P P P P P P P P P P P P P P P G GP P RBFOX2 FBXO7 26186194, 25402006 biogrid exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G CDC34 FBXO7 10531035, 25402006, 21836163 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TCEB3 FBXO7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G FBXL2 FBXO7 25402006 pred G G G G G G G G G G G G G G G G G G G G G FBXO5 FBXO7 25402006, 16082366 pred P P G GP P P GP P P P P GP P GP P P P P P GP G P P FBXO11 FBXO7 21836163 pred G G G G G GP G G G G G GP GP G G GP GP G G G GP G G G GP G G G G RBFOX1 FBXO7 25402006 pred P G G G GP G GP GP G P P P GP GP G GP G G G GP GP GP P GP G TCEB2 FBXO7 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP1 FBXO7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXW11 FBXO7 25402006, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G APOE FBXO7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G G GP GP G G GP GP G G G G GP GP G FBXW4 FBXO7 16082366 pred G G G G GP G G G G G G G GP G G GP G G GP G GP G G G GP G G G G UBXN1 FBXO7 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP G GP GP G VHL FBXO7 23023127 pred G G G G G G G G G G GP GP GP G G G G G P G G GP GP G G G G GP G CDKN2C FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP G GP GP G FBXL3 FBXO7 25402006 pred G G G G GP G G G G G G G G G G G G G G G G G G G G G G G G GPIHBP1 FBXO7 23023127 pred G G G G G G G G G G G G G G G G G G G GSPT1 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXO7 TRAF6 25402006 pred GP GP G G GP G G GP GP G GP GP GP G G GP G GP G G GP GP GP G GP G GP GP G SKP2 FBXO7 25402006, 21836163 pred GP GP G G GP GP G GP GP G G GP GP GP G GP GP G GP G GP G G GP GP G GP GP G CUL4B FBXO7 21836163 pred GP GP G G GP GP G GP GP G GP GP G GP G GP GP G GP G GP GP GP GP GP G GP GP G FBXO27 FBXO7 23023127 pred GP P G GP G GP GP G GP G P GP G P GP G G P GP GP GP GP GP GP G FBXO6 FBXO7 25402006, 16082366 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP G GP GP G TNFSF14 FBXO7 25402006 pred GP P P P P P P GP GP G P P G P P P P P G P P NFKBIB FBXO7 25402006 pred GP P G GP GP G GP P G GP GP GP GP G GP GP P GP G GP GP GP GP GP G GP GP G UBE4A FBXO7 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXO18 FBXO7 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CDKN2D FBXO7 25402006 pred P P G G GP GP G P GP G P P GP GP P GP P P P P P P P G P GP RCHY1 FBXO7 21836163 pred G GP G G G GP G GP GP G GP G GP G G GP GP G GP G G G GP G GP G GP G G CDKN2A FBXO7 25402006 pred G GP G G GP GP G G G G G G GP GP G G GP G GP G GP G G G G G GP G G GCM1 FBXO7 21836163 pred P P GP P FBXW8 FBXO7 16082366 pred P P P P P P P P P P P P P P P P P P P P BCR FBXO7 16082366 pred UBQLN2 FBXO7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G UBE2J1 FBXO7 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP G GP GP G BCL2 FBXO7 23023127 pred G G G G GP GP G G GP G GP G G GP G G GP GP G G GP GP G G G G G G G GABARAP FBXO7 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDKN1A FBXO7 25402006 pred GP GP G G GP G G G GP G G G GP G G GP G G G G GP G G G GP G G GP G LDOC1 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G G GP GP G GP G GP GP G RNF144B FBXO7 21836163 pred G GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G G G GP G G GP G BEND7 FBXO7 25402006 pred G G G P GP G GP GP G GP GP GP G G GP GP G G G GP G G G GP G GP GP G CTNNB1 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP G GP GP G CDC37 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G UBXN7 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G MDM4 FBXO7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G BCL10 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G STX12 FBXO7 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G MXD1 FBXO7 25402006 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP G GP GP G FBXO22 FBXO7 16082366 pred G G G G G G G G G G G G G G G G G G G G G NEDD8 FBXO7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXO34 FBXO7 25402006 pred G GP G G G G G G GP G G G G G G G G G G G GP G G GP G G GP GP G MAP4K4 FBXO7 25402006 pred G G G G G GP G GP G G GP GP GP G G GP GP G G G G G G G GP G GP GP G FBXO31 FBXO7 25402006, 23023127, 21836163 pred GP GP G P GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 FBXO7 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G RUNX1 FBXO7 25402006 pred P P P P P P P P P P P P P P P P P P P CAND1 FBXO7 25402006, 21836163 pred G GP G G G G G G GP G GP GP G G G GP G GP G G G G GP GP GP G G GP G HSP90B1 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXL5 FBXO7 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RPL22 FBXO7 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NFKBIE FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP GP G GP GP G UBE2M FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP G GP GP G KHDRBS3 FBXO7 25402006 pred GP GP G P GP G GP GP G GP G G GP G GP GP GP GP G P GP GP GP GP G GP GP G FBXO3 FBXO7 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BTRC FBXO7 25402006, 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXW7 FBXO7 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP G GP GP NLK FBXO7 21836163 pred GP GP G G GP GP G G GP G G G G G G G GP G G G GP GP G G G G G GP G SASH1 FBXO7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G G GP G GP G GP GP GP GP G G GP GP G TNRC6C FBXO7 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP G GP GP G FBXO25 FBXO7 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CUL2 FBXO7 21836163 pred GP GP G G G GP G G GP G GP GP GP GP G G GP GP GP G GP GP GP G G G GP GP G MYLIP FBXO7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF103 FBXO7 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G G GP G G GP G GP GP G CUL7 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXL20 FBXO7 21836163 pred GP GP G G GP G G G GP G GP GP GP GP G GP G G GP G GP GP GP G GP G GP GP G TRAF3 FBXO7 25402006 pred G GP G G GP GP G G G G GP GP GP GP G GP GP GP GP G GP G GP G GP G GP GP G TMEM59 FBXO7 21836163 pred G G G G G GP G G GP G GP G GP G G G GP G G G G G G G G G G G G SENP8 FBXO7 21836163 pred P P G P GP G GP P G GP P P P P P GP P G P GP P GP GP P GP FAF1 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G MDM2 FBXO7 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G ZC3HC1 FBXO7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXL6 FBXO7 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ACVR1 FBXO7 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP G GP GP G NFKBIA FBXO7 25402006 pred G GP G G GP GP G GP GP G G G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G FBXO2 FBXO7 25402006, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD3 FBXO7 25402006 pred GP GP G G G GP G G G G G G GP GP G G GP G GP G GP G G G G G G G G SMURF2 FBXO7 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HTRA2 FBXO7 25402006 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G FBXO4 FBXO7 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9Y3I1 - 16096642 - X 2 P63208 Q9Y3I1 anti tag coimmunoprecipitation 20596027 physical association X 2 Q9Y3I1 anti tag coimmunoprecipitation 24811749 association C 66 Q7Z6E9 Q9Y3I1 two hybrid 18624398 physical association X 2 P63209 Q9Y3I1 pull down 10531035 direct interaction X 2 P63209 Q9Y3I1 beta lactamase complementation 10531035 physical association X 2 O60260 Q9Y3I1 pull down 23933751 physical association X 2 O60260 Q9Y3I1 pull down 23933751 physical association X 2 O60260 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 O60260 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 O60260 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 O60260 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 O60260 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 O60260 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 O60260 Q9Y3I1 anti bait coimmunoprecipitation 23933751 physical association X 2 O60260 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 Q92530 Q9Y3I1 two hybrid prey pooling approach 25416956 physical association X 2 Q92530 Q9Y3I1 two hybrid array 25416956 physical association X 2 Q92530 Q9Y3I1 validated two hybrid 25416956 physical association X 2 P25788 Q9Y3I1 two hybrid prey pooling approach 25416956 physical association X 2 P25788 Q9Y3I1 two hybrid array 25416956 physical association X 2 P25788 Q9Y3I1 validated two hybrid 25416956 physical association X 2 P63208 Q9Y3I1 anti tag coimmunoprecipitation 22632967 physical association X 2 P63208 Q9Y3I1 mammalian protein protein interaction trap 25416956 physical association X 2 Q9BXM7 Q9Y3I1 pull down 23933751 physical association X 2 Q9BXM7 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 Q9BXM7 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 Q9BXM7 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 Q9BXM7 Q9Y3I1 pull down 23933751 physical association X 2 Q9BXM7 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 Q9BXM7 Q9Y3I1 anti tag coimmunoprecipitation 23933751 physical association X 2 Q9BXM7 Q9Y3I1 pull down 23933751 physical association X 2 Q9Y3I1 anti tag coimmunoprecipitation 16278047 association C 3 Q9Y3I1 anti tag coimmunoprecipitation 19615732 physical association C 55 Q9Y3I1 pull down 23933751 association C 3 Q9Y3I1 pull down 23933751 association C 3 Q9Y3I1 pull down 23933751 association C 3 Q5NIE3 Q9Y3I1 two hybrid pooling approach 20711500 physical association X 2 Q9Y3I1 A0A024QZM6 two hybrid array 21988832 physical association X 2 P61289 Q9Y3I1 two hybrid prey pooling approach 25416956 physical association X 2 P61289 Q9Y3I1 two hybrid array 25416956 physical association X 2 P61289 Q9Y3I1 validated two hybrid 25416956 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality RBFOX2 FBXO7 26186194 0004 HT XPOT FBXO7 26496610,26496610 0007,0004 HT ZBTB48 FBXO7 26496610,26496610 0007,0004 HT HSPD1 FBXO7 26496610,26496610 0007,0004 HT TSHR FBXO7 26186194 0004 HT PSMB9 FBXO7 26186194 0004 HT PSMB4 FBXO7 26186194 0004 HT BCAT1 FBXO7 26186194 0004 HT PSMA6 FBXO7 26496610,26496610 0007,0004 HT SKP1 FBXO7 16278047,10531035,21378169,10531037,22632967,15145941,26496610,10531037,26496610,10531037,20596027,10531035,16278047,10531035 0007,0096,0096,0018,0007,0004,0004,0004,0007,0096,0007,0004,0004,0018 LC,HT CDK6 FBXO7 16096642,16096642,18495667 0019,0004,0004 LC TRAF2 FBXO7 22212761,25029497 0004,0004 LC BIRC2 FBXO7 16510124,22212761,16510124,16510124 0018,0004,0004,0007 LC CUL1 FBXO7 16278047,16278047,26496610,26496610,21145461,18495667,15145941,10531035 0007,0004,0004,0007,0004,0004,0004,0004 LC,HT PDE3A FBXO7 26496610,26496610 0007,0004 HT ESPL1 FBXO7 26496610,26496610 0007,0004 HT TCEB1 FBXO7 26496610,26496610 0007,0004 HT PARP10 FBXO7 26496610,26496610 0007,0004 HT Q59EL2 FBXO7 26186194 0004 HT COPS6 FBXO7 19615732,21145461,19615732 0004,0004,0007 HT PSMF1 FBXO7 26496610,18495667,26496610,18495667,18495667 0004,0018,0007,0096,0004 HT,LC GBF1 FBXO7 26496610,26496610 0007,0004 HT COPS5 FBXO7 21145461 0004 HT SIRT1 FBXO7 26496610,26496610 0007,0004 HT PANX1 FBXO7 26496610,26496610 0007,0004 HT PSMB7 FBXO7 26186194 0004 HT PRMT1 FBXO7 26496610,26496610 0007,0004 HT SRRT FBXO7 26496610,26496610 0007,0004 HT CRNKL1 FBXO7 26496610,26496610 0007,0004 HT ESF1 FBXO7 26496610,26496610 0007,0004 HT PVRL3 FBXO7 26496610,26496610 0007,0004 HT Q9P1R6 FBXO7 26186194 0004 HT FBXW2 FBXO7 26496610,26496610 0007,0004 HT NSFL1C FBXO7 26496610,26496610 0007,0004 HT HPSE FBXO7 26496610,26496610 0007,0004 HT RBFOX2 FBXO7 26186194 0004 HT XPOT FBXO7 26496610,26496610 0007,0004 HT ZBTB48 FBXO7 26496610,26496610 0007,0004 HT HSPD1 FBXO7 26496610,26496610 0007,0004 HT TSHR FBXO7 26186194 0004 HT PSMB9 FBXO7 26186194 0004 HT PSMB4 FBXO7 26186194 0004 HT BCAT1 FBXO7 26186194 0004 HT PSMA6 FBXO7 26496610,26496610 0007,0004 HT SKP1 FBXO7 26496610,26496610 0004,0007 HT CUL1 FBXO7 26496610,26496610,21145461 0004,0007,0004 HT PDE3A FBXO7 26496610,26496610 0007,0004 HT ESPL1 FBXO7 26496610,26496610 0007,0004 HT TCEB1 FBXO7 26496610,26496610 0007,0004 HT PARP10 FBXO7 26496610,26496610 0007,0004 HT Q59EL2 FBXO7 26186194 0004 HT COPS6 FBXO7 19615732,21145461,19615732 0004,0004,0007 HT PSMF1 FBXO7 26496610,26496610 0004,0007 HT GBF1 FBXO7 26496610,26496610 0007,0004 HT COPS5 FBXO7 21145461 0004 HT SIRT1 FBXO7 26496610,26496610 0007,0004 HT PANX1 FBXO7 26496610,26496610 0007,0004 HT PSMB7 FBXO7 26186194 0004 HT PRMT1 FBXO7 26496610,26496610 0007,0004 HT SRRT FBXO7 26496610,26496610 0007,0004 HT CRNKL1 FBXO7 26496610,26496610 0007,0004 HT ESF1 FBXO7 26496610,26496610 0007,0004 HT PVRL3 FBXO7 26496610,26496610 0007,0004 HT Q9P1R6 FBXO7 26186194 0004 HT FBXW2 FBXO7 26496610,26496610 0007,0004 HT NSFL1C FBXO7 26496610,26496610 0007,0004 HT HPSE FBXO7 26496610,26496610 0007,0004 HT SKP1 FBXO7 16278047,10531035,21378169,10531037,22632967,15145941,10531037,10531037,20596027,10531035,16278047,10531035 0007,0096,0096,0018,0007,0004,0004,0096,0007,0004,0004,0018 LC CDK6 FBXO7 16096642,16096642,18495667 0019,0004,0004 LC TRAF2 FBXO7 22212761,25029497 0004,0004 LC BIRC2 FBXO7 16510124,22212761,16510124,16510124 0018,0004,0004,0007 LC CUL1 FBXO7 16278047,16278047,18495667,15145941,10531035 0007,0004,0004,0004,0004 LC PSMF1 FBXO7 18495667,18495667,18495667 0018,0096,0004 LC CCND1 FBXO7 16096642 0019 LC PSMA3 FBXO7 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT CCND3 FBXO7 16096642 0019 LC CDKN1B FBXO7 16096642,16096642 0019,0004 LC CDC34 FBXO7 10531035 0415 LC SEC24C FBXO7 21988832,21988832 0397,0018 HT PSME3 FBXO7 25416956,25416956,25416956 1112,0397,1356 HT UBE2D2 FBXO7 10531035 0415 LC RBX1 FBXO7 16096642 0019 LC SKP1 FBXO7 10531035,10531037,24947323,10531037,10531037,10531035,16096642,25416956,10531035 0096,0018,0018,0004,0096,0004,0019,0231,0018 LC,HT CDK6 FBXO7 16096642,16096642 0019,0004 LC BIRC2 FBXO7 16510124,16510124,16510124 0018,0004,0007 LC RBBP6 FBXO7 18624398 0018 HT PSMF1 FBXO7 18495667,25416956,25416956,25416956,25416956,18495667,18495667 0018,1112,0397,0018,1356,0096,0004 LC,HT FBXO7 FBXO7 24419388 0114 LC FBXO7 MAGED1 24947323,24947323 0004,0018 LC FBXO7 HEL-S-283 25416956 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y3I1 Q5NIE3 FBXO7 GLPA 0.126 20711500 Q9Y3I1 O14980 FBXO7 XPO1 0.309 21378169 Q9Y3I1 O43251 FBXO7 RBFOX2 0.126 26186194 Q9Y3I1 P61201 FBXO7 COPS2 0.126 26186194 Q9Y5V3 Q9Y3I1 MAGED1 FBXO7 0.569 24947323 Q9Y3I1 Q9NQS3 FBXO7 PVRL3 0.126 26496610 Q9Y3I1 Q96RD7 FBXO7 PANX1 0.126 26496610 Q9Y3I1 Q9UNZ2 FBXO7 NSFL1C 0.126 26496610 Q9Y3I1 Q92538 FBXO7 GBF1 0.126 26496610 Q9Y3I1 Q15398 FBXO7 DLGAP5 0.21 15145941 Q9Y3I1 Q4VXH1 FBXO7 FBXW2 {ECO:0000313|ENSEMBL:ENSP00000398662} 0.126 26496610 Q9Y3I1 Q14674 FBXO7 ESPL1 0.126 26496610 Q9Y3I1 P10074 FBXO7 ZBTB48 0.126 26496610 Q9Y3I1 E9PK67 FBXO7 PARP10 {ECO:0000313|ENSEMBL:ENSP00000431620} 0.126 26496610 Q9Y3I1 K7ENV2 FBXO7 ZBTB48 {ECO:0000313|ENSEMBL:ENSP00000467104} 0.126 26496610 Q9Y3I1 Q53GL7 FBXO7 PARP10 0.126 26496610 Q9Y3I1 Q5QPM7 FBXO7 PSMF1 {ECO:0000313|ENSEMBL:ENSP00000246015} 0.126 26496610 Q9Y3I1 E5RHG8 FBXO7 TCEB1 {ECO:0000313|ENSEMBL:ENSP00000429789} 0.126 26496610 Q9Y3I1 P0CG48 FBXO7 UBC 0.126 16196087 Q9Y3I1 Q9WTX5 FBXO7 SKP1 0.236 26496610 Q9Y3I1 Q9WTX6 FBXO7 CUL1 0.236 26496610 Q9Y3I1 O43592 FBXO7 XPOT 0.236 26496610 Q9Y3I1 P10809 FBXO7 HSPD1 0.236 26496610 Q9Y3I1 P60900 FBXO7 PSMA6 0.236 26496610 Q9Y3I1 P61289 FBXO7 PSME3 0.454 25416956 Q9Y3I1 Q14432 FBXO7 PDE3A 0.236 26496610 Q9Y3I1 Q96EB6 FBXO7 SIRT1 0.236 26496610 Q9Y3I1 Q99873 FBXO7 PRMT1 0.236 26496610 Q9Y3I1 Q9BXP5 FBXO7 SRRT 0.236 26496610 Q9Y3I1 Q9BZJ0 FBXO7 CRNKL1 0.236 26496610 Q9Y3I1 Q9H501 FBXO7 ESF1 0.236 26496610 Q9Y3I1 Q9Y251 FBXO7 HPSE 0.236 26496610 Q9Y3I1 P99026 FBXO7 PSMB4 0.236 26496610 Q9Y3I1 Q12933 FBXO7 TRAF2 0.376 25029497,22212761 Q9Y3I1 Q7Z6E9 FBXO7 RBBP6 0.332 18624398 Q9Y3I1 O55234 FBXO7 PSMB5 0.236 26496610 Q9Y3I1 P60896 FBXO7 SHFM1 0.236 24811749 Q9Y3I1 P63209 FBXO7 SKP1 0.454 10531035 Q9Y3I1 Q7L5N1 FBXO7 COPS6 0.332 19615732,21145461 Q9Y3I1 Q9BXM7 FBXO7 PINK1 0.832 23933751 Q9Y3I1 P63208 FBXO7 SKP1 0.964 25416956,24947323,22632967,21378169,10531037,26496610,16278047,10531035,27705803,15145941 Q9Y3I1 O60260 FBXO7 PARK2 0.928 23933751 Q9Y3I1 Q92530 FBXO7 PSMF1 0.943 25416956,18495667,25910212,26496610 Q9Y3I1 P25788 FBXO7 PSMA3 0.636 25416956,25910212 Q9Y3I1 Q92905 FBXO7 COPS5 0.126 21145461 Q9Y3I1 P28065 FBXO7 PSMB9 0.126 26186194 Q9Y3I1 Q99436 FBXO7 PSMB7 0.126 26186194 Q9Y3I1 Q13616 FBXO7 CUL1 0.702 16278047,10531035,15145941,21145461,18495667,26496610 Q9Y3I1 P16473 FBXO7 TSHR 0.126 26186194 Q9Y3I1 P62837 FBXO7 UBE2D2 0.309 10531035 Q9Y3I1 P49427 FBXO7 CDC34 0.309 10531035 Q9Y3I1 Q00534 FBXO7 CDK6 0.21 18495667 Q9Y3I1 Q13490 FBXO7 BIRC2 0.376 16510124,22212761 Q9Y3I1 P53992 FBXO7 SEC24C 0.286 21988832 Q9Y3I1 P54687 FBXO7 BCAT1 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 XPO1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database RBFOX2 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database SIAH2 FBXO7 MI:0362 inference MI:1106 pathways database XPOT FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PARK2 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database FBXO21 FBXO7 MI:0362 inference MI:1106 pathways database UBB FBXO7 MI:0362 inference MI:1106 pathways database UBC FBXO7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ZBTB48 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database HSPD1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database TSHR FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database TRIM21 FBXO7 MI:0362 inference MI:1106 pathways database TAF1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database CCND1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database POLR2A FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PSMA3 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PSMB9 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PSMB4 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PSMB5 FBXO7 MI:0362 inference MI:0461 interaction database CCND3 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database CCNF FBXO7 MI:0362 inference MI:1106 pathways database CDKN1B FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database CDC34 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database UBE2A FBXO7 MI:0362 inference MI:1106 pathways database SEC24C FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database BCAT1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database FBXW4 FBXO7 MI:0362 inference MI:1106 pathways database SHFM1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PSMA6 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database COPS2 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PSME3 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database RBX1 FBXO7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RPS27A FBXO7 MI:0362 inference MI:1106 pathways database UBA52 FBXO7 MI:0362 inference MI:1106 pathways database SKP1 FBXO7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CDK6 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database TRAF2 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database SKP2 FBXO7 MI:0362 inference MI:1106 pathways database BIRC2 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database CUL1 FBXO7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PDE3A FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database TRIP12 FBXO7 MI:0362 inference MI:1106 pathways database ESPL1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database TCEB1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database DLGAP5 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database NEDD8 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database LONRF1 FBXO7 MI:0362 inference MI:1106 pathways database PARP10 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database HECTD2 FBXO7 MI:0362 inference MI:1106 pathways database FBXO31 FBXO7 MI:0362 inference MI:1106 pathways database FBXW9 FBXO7 MI:0362 inference MI:1106 pathways database FBXW10 FBXO7 MI:0362 inference MI:1106 pathways database RNF213 FBXO7 MI:0362 inference MI:1106 pathways database FBXL22 FBXO7 MI:0362 inference MI:1106 pathways database FBXL19 FBXO7 MI:0362 inference MI:1106 pathways database FBXW12 FBXO7 MI:0362 inference MI:1106 pathways database RNF19B FBXO7 MI:0362 inference MI:1106 pathways database COPS6 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database RNF144B FBXO7 MI:0362 inference MI:1106 pathways database RBBP6 FBXO7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HUWE1 FBXO7 MI:0362 inference MI:1106 pathways database TRIM69 FBXO7 MI:0362 inference MI:1106 pathways database SIAH1 FBXO7 MI:0362 inference MI:1106 pathways database HERC6 FBXO7 MI:0362 inference MI:1106 pathways database UBR2 FBXO7 MI:0362 inference MI:1106 pathways database FBXL14 FBXO7 MI:0362 inference MI:1106 pathways database FBXW8 FBXO7 MI:0362 inference MI:1106 pathways database FBXL16 FBXO7 MI:0362 inference MI:1106 pathways database FBXO15 FBXO7 MI:0362 inference MI:1106 pathways database ZNRF1 FBXO7 MI:0362 inference MI:1106 pathways database FBXL13 FBXO7 MI:0362 inference MI:1106 pathways database FBXO22 FBXO7 MI:0362 inference MI:1106 pathways database ZNRF2 FBXO7 MI:0362 inference MI:1106 pathways database FBXO27 FBXO7 MI:0362 inference MI:1106 pathways database FBXO30 FBXO7 MI:0362 inference MI:1106 pathways database RNF217 FBXO7 MI:0362 inference MI:1106 pathways database FBXO25 FBXO7 MI:0362 inference MI:0461 interaction database DTX3L FBXO7 MI:0362 inference MI:1106 pathways database FBXO41 FBXO7 MI:0362 inference MI:1106 pathways database LMO7 FBXO7 MI:0362 inference MI:1106 pathways database MYLIP FBXO7 MI:0362 inference MI:1106 pathways database PSMF1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database GBF1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database COPS5 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database FBXW7 FBXO7 MI:0362 inference MI:1106 pathways database FBXO32 FBXO7 MI:0362 inference MI:1106 pathways database FBXW5 FBXO7 MI:0362 inference MI:1106 pathways database PSMG2 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database MIB2 FBXO7 MI:0362 inference MI:1106 pathways database SPSB1 FBXO7 MI:0362 inference MI:1106 pathways database FBXL8 FBXO7 MI:0362 inference MI:1106 pathways database SIRT1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database FBXO17 FBXO7 MI:0362 inference MI:1106 pathways database FBXL20 FBXO7 MI:0362 inference MI:1106 pathways database FBXL18 FBXO7 MI:0362 inference MI:1106 pathways database NEDD4L FBXO7 MI:0362 inference MI:1106 pathways database PANX1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PSMB7 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PRMT1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database PINK1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database SRRT FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 FBXO7 MI:0362 inference MI:1106 pathways database CRNKL1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database FBXL15 FBXO7 MI:0362 inference MI:1106 pathways database FBXO44 FBXO7 MI:0362 inference MI:1106 pathways database ESF1 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database UNKL FBXO7 MI:0362 inference MI:1106 pathways database SMURF2 FBXO7 MI:0362 inference MI:1106 pathways database TRIM36 FBXO7 MI:0362 inference MI:1106 pathways database NECTIN3 FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database FBXO6 FBXO7 MI:0362 inference MI:1106 pathways database RNF19A FBXO7 MI:0362 inference MI:1106 pathways database RLIM FBXO7 MI:0362 inference MI:1106 pathways database FBXL12 FBXO7 MI:0362 inference MI:1106 pathways database FBXO40 FBXO7 MI:0362 inference MI:1106 pathways database HERC5 FBXO7 MI:0362 inference MI:1106 pathways database FBXL7 FBXO7 MI:0362 inference MI:1106 pathways database FBXO2 FBXO7 MI:0362 inference MI:1106 pathways database FBXO10 FBXO7 MI:0362 inference MI:1106 pathways database FBXO9 FBXO7 MI:0362 inference MI:1106 pathways database FBXL5 FBXO7 MI:0362 inference MI:1106 pathways database FBXL4 FBXO7 MI:0362 inference MI:1106 pathways database FBXW11 FBXO7 MI:0362 inference MI:1106 pathways database FBXO4 FBXO7 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database FBXL21 FBXO7 MI:0362 inference MI:1106 pathways database FBXL3 FBXO7 MI:0362 inference MI:1106 pathways database FBXW2 FBXO7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NSFL1C FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database HPSE FBXO7 MI:0045 experimental interaction detection MI:0461 interaction database BTRC FBXO7 MI:0362 inference MI:1106 pathways database FBXO7 RNF115 MI:0362 inference MI:1106 pathways database FBXO7 RNF114 MI:0362 inference MI:1106 pathways database FBXO7 MAGED1 MI:0045 experimental interaction detection MI:0461 interaction database FBXO7 WSB1 MI:0362 inference MI:1106 pathways database