Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 22 40303934 rs137963 C T rs137963 8.30E-05 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 C intron GWASdb_drug 22 40336845 rs137989 T C rs137989 6.80E-05 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_drug 22 40340775 rs137991 T C rs137991 9.10E-05 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_drug 22 40303934 rs137963 C T rs137963 8.30E-05 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 C intron GWASdb_trait 22 40320361 rs137977 C A rs137977 1.04E-04 Bipolar disorder HPOID:0007302 DOID:3312 A intron GWASdb_trait 22 40336845 rs137989 T C rs137989 6.80E-05 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_trait 22 40340775 rs137991 T C rs137991 9.10E-05 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_trait 22 40348520 rs2267420 G A rs2267420 3.73E-05 HIV-1 progression HPOID:0002721 DOID:526 A intron GWASdb_trait 22 40357667 rs9611234 G A rs9611234 2.05E-05 Bipolar disorder and schizophrenia HPOID:0007302|HPOID:0100753 DOID:3312|DOID:5419 G intron GWASdb_trait 22 40362946 rs138006 A G rs138006 1.83E-04 Alzheimer's disease HPOID:0002511 DOID:10652 G intron GWASdb_trait 22 40363778 rs2284078 G A rs2284078 2.44E-04 Alzheimer's disease HPOID:0002511 DOID:10652 A intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000100351.16 GRAP2 604518