DNA & RNA Element - UTRdb Gene Name Type ASPicDB UTRaspic Refseq ID Genome RBX1 3'UTR 1108bd8f9c BA089764 NM_014248 chr22:39698439-39698614:+ RBX1 3'UTR 8a098cd8ec BA089765 NM_014248 chr22:39698439-39698524:+ RBX1 3'UTR 136cda44f4 BA089766 NM_014248 chr22:39698439-39699053:+ RBX1 5'UTR 1108bd8f9c CA140922 NM_014248 chr22:39677331-39677348:+ RBX1 5'UTR 8a098cd8ec CA140923 NM_014248 chr22:39677297-39677348:+ RBX1 5'UTR 136cda44f4 CA140924 NM_014248 chr22:39677297-39677348:+

DNA & RNA Element - AREsite Gene Name Motif CDS Area ARE Area Evidence RBX1; RNF75; ROC1 ATTTA 41-367 408-412 Identification of TTP mRNA targets in human dendritic cells#RNA 2008; 14(5): 888-902.!Identification of a target RNA motif for RNA-binding protein HuR.#Proc Natl Acad Sci U S A 2004; 101(9): 2987-92.!

DNA & RNA Element - circBase circRNA ID Chrom Start End Strand hsa_circ_0063477 chr22 41360050 41360121 + hsa_circ_0008884 chr22 41349558 41360121 + hsa_circ_0004469 chr22 41349558 41363888 + hsa_circ_0063476 chr22 41347350 41360121 +

DNA & RNA Element - circRNADb circRNA ID Chrom Start End Strand Samples hsa_circ_01843 chr22 41349558 41363888 + H9 hESCs,oligodendroma,Hs68 hsa_circ_28612 chr22 41349558 41360121 + normal brain tissue,Hs68

DNA & RNA Element - CircNet Circ ID GITPosition Express Symbol Entrez Category Strand Refered Name hsa-circ-RBX1-overlap.1 NM_014248Tchr22:41349559-41360238 expressed RBX1 9978 protein-coding not_available not_available hsa-circ-RBX1-overlap.2 NM_014248Tchr22:41349559-41351450 expressed RBX1 9978 protein-coding not_available not_available hsa-circ-RBX1-overlap.4 NM_014248Tchr22:41349558-41351450 expressed RBX1 9978 protein-coding + not_available hsa-circ-RBX1-overlap.5 NM_014248Tchr22:41368479-41368972 expressed RBX1 9978 protein-coding + not_available hsa-circ-RBX1.2 NM_014248Tchr22:41349558-41360121 expressed RBX1 9978 protein-coding + hsa_circ_0008884 hsa-circ-RBX1.3 NM_014248Tchr22:41360050-41360121 expressed RBX1 9978 protein-coding + hsa_circ_0063477 hsa-circ-RBX1.4 NM_014248Tchr22:41347350-41360121 expressed RBX1 9978 protein-coding + hsa_circ_0063476 hsa-circ-RBX1.5 NM_014248Tchr22:41349559-41363888 none RBX1 9978 protein-coding not_available not_available hsa-circ-RBX1.7 NM_014248Tchr22:41360050-41363888 expressed RBX1 9978 protein-coding + hsa_circ_0116605

DNA & RNA Element - miRTarBase Target Gene (Entrez ID) miRTarBase ID miRNA Species (miRNA) Target Gene Species (Target Gene) Experiments Support Type References (PMID) MIRT049206 hsa-miR-92a-3p Homo sapiens RBX1 9978 Homo sapiens CLASH Functional MTI (Weak) 23622248 MIRT054190 hsa-miR-194-5p Homo sapiens RBX1 9978 Homo sapiens Flow//Luciferase reporter assay//qRT-PCR//Western blot Functional MTI 25412959 MIRT719965 hsa-miR-6875-3p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719966 hsa-miR-4439 Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719967 hsa-miR-3136-5p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719968 hsa-miR-642a-5p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719969 hsa-miR-188-3p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719970 hsa-miR-6857-3p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719971 hsa-miR-6855-3p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719972 hsa-miR-4513 Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719973 hsa-miR-5187-3p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719974 hsa-miR-2276-5p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157 MIRT719975 hsa-miR-6892-3p Homo sapiens RBX1 9978 Homo sapiens HITS-CLIP Functional MTI (Weak) 19536157

DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0004481 hsa-let-7a* 9978 RBX1 cuuucugucaUCUAACAUAuc | ||||||| uucuguagccAUAUUGUAUuc 3 12 124 144 [hg19:22:41368616-41368636:+] 0.7202 127 0 -8.75 -0.1304 MIMAT0004482 hsa-let-7b* 9978 RBX1 ccCUUCCGUCAUCCAACAUAuc | || || || |||||| cuGUAGCCA-UA--UUGUAUuc 3 21 126 144 [hg19:22:41368618-41368636:+] 0.7202 127 0 -6.51 -0.1196 MIMAT0004486 hsa-let-7f-1* 9978 RBX1 cccuucCGUUAUCUAACAUAuc || || ||||||| ucuguaGCCAU--AUUGUAUuc 3 17 125 144 [hg19:22:41368617-41368636:+] 0.7202 129 0 -6.30 -0.1278 MIMAT0004512 hsa-miR-100* 9978 RBX1 guaUGGA-UAUCUAUGUUCGAAc ||:| | || ||||||| aagACUUCUUCCAU-CAAGCUUa 2 20 4 25 [hg19:22:41368496-41368517:+] 0.7202 144 7 -9.84 -1.0875 MIMAT0004553 hsa-miR-7-1* 9978 RBX1 auaccgucuGACACUAAACAAc :| || |||||| uguguuuuuUUCUGCUUUGUUu 2 14 88 109 [hg19:22:41368580-41368601:+] 0.7202 121 6 -5.75 -0.1810 MIMAT0004553 hsa-miR-7-1* 9978 RBX1 auaccgucugacacuAAACAAc |||||| aucaagcuuaauuguUUUGUUa 2 8 16 37 [hg19:22:41368508-41368529:+] 0.7202 120 6 -7.37 -0.2660 MIMAT0004554 hsa-miR-7-2* 9978 RBX1 aauccaucugacccuAAACAAc |||||| aucaagcuuaauuguUUUGUUa 2 8 16 37 [hg19:22:41368508-41368529:+] 0.7202 120 6 -5.30 -0.2660 MIMAT0004554 hsa-miR-7-2* 9978 RBX1 aauccaucugacccuAAACAAc |||||| uguguuuuuuucugcUUUGUUu 2 8 88 109 [hg19:22:41368580-41368601:+] 0.7202 120 6 -4.96 -0.1793 MIMAT0004561 hsa-miR-187* 9978 RBX1 cgGGCCCAGGACACA-ACAUCGg | | | |||| | |||||| uuCAGUUUGCUGUUUCUGUAGCc 2 21 111 133 [hg19:22:41368603-41368625:+] 0.7202 124 6 -17.80 -1.2881 MIMAT0004610 hsa-miR-150* 9978 RBX1 gaCAGGGGGUCCGGACAU-GGUc ||:: |:: :||||| ||| caGUUUGCUGUUUCUGUAGCCAu 2 21 113 135 [hg19:22:41368605-41368627:+] 0.7202 120 0 -14.17 -1.2058 MIMAT0009199 hsa-miR-365* 9978 RBX1 ugucgACGGGGACUUUCAGGga ||:| ||||||| uucugUGUCAAAUAAAGUCCag 3 18 142 163 [hg19:22:41368634-41368655:+] 0.7202 129 0 -16.24 -0.3091 MIMAT0000735 hsa-miR-380 9978 RBX1 uuCUACACCUGGUAUAAUGUau | ||| ||| |||||| cuGCUGU-UACCUAAUUACAaa 3 21 56 76 [hg19:22:41368548-41368568:+] 0.7202 134 0 -7.46 -0.2417 MIMAT0000751 hsa-miR-330-3p 9978 RBX1 agaGACGU-CCGGCACACGAAACg |||:: :: | ||||||| gaaCUGUGUUUUUUUCUGCUUUGu 2 21 84 107 [hg19:22:41368576-41368599:+] 0.7202 143 7 -14.32 -1.2222 MIMAT0004700 hsa-miR-331-5p 9978 RBX1 ccuagggacccugguAUGGAUc |||||| gacuuucccugcuguUACCUAa 2 8 48 69 [hg19:22:41368540-41368561:+] 0.7202 120 6 -15.85 -0.3337 MIMAT0004701 hsa-miR-338-5p 9978 RBX1 guGAGUCGUGGUCCUAUAACAa :|| |:| | ||||||| guUUCUGUAGC--CAUAUUGUa 2 21 122 141 [hg19:22:41368614-41368633:+] 0.7202 145 7 -10.32 -1.0119 MIMAT0002849 hsa-miR-524-5p 9978 RBX1 cucuuucACGAAGG-GAAACAuc | :|||: |||||| cuguguuUUUUUCUGCUUUGUuu 3 16 87 109 [hg19:22:41368579-41368601:+] 0.7202 130 0 -10.62 -0.1466 MIMAT0002855 hsa-miR-520d-5p 9978 RBX1 cuuucccGAAGG-GAAACAuc :|||: |||||| guguuuuUUUCUGCUUUGUuu 3 14 89 109 [hg19:22:41368581-41368601:+] 0.7202 128 0 -9.11 -0.1494 MIMAT0002883 hsa-miR-514 9978 RBX1 agaugagugucuuCACAGUUa ||||||| cauauuguauucuGUGUCAAa 2 9 133 153 [hg19:22:41368625-41368645:+] 0.7202 140 7 -10.98 -1.3201 MIMAT0003165 hsa-miR-545 9978 RBX1 cguguguuauuuaCAAACGACu |||||||| cuuuguuuuuucaGUUUGCUGu 2 10 102 123 [hg19:22:41368594-41368615:+] 0.7202 145 7 -12.01 -1.1907 MIMAT0003235 hsa-miR-570 9978 RBX1 cgUUUCCAUUAACGACAAAAGc ::| | || || ||||||: uuGGAUGGAACUG-UGUUUUUu 2 21 77 97 [hg19:22:41368569-41368589:+] 0.7202 138 0 -5.62 -0.1215 MIMAT0003235 hsa-miR-570 9978 RBX1 cguuuccauuaACG--ACAAAAGc ||| ||||||: guguuuuuuucUGCUUUGUUUUUu 2 12 89 112 [hg19:22:41368581-41368604:+] 0.7202 126 0 -4.85 -0.1395 MIMAT0003247 hsa-miR-582-5p 9978 RBX1 ucaUUGACCAACUUGUUGACAUu ||:||| ||: ||||||: acaAAUUGGAUGG--AACUGUGu 2 21 72 92 [hg19:22:41368564-41368584:+] 0.7202 145 0 -17.02 -0.1393 MIMAT0003251 hsa-miR-548a-3p 9978 RBX1 cguuuucauuAACGGUCAAAac || :|||||| cugcuuuguuUUUUCAGUUUgc 3 13 99 120 [hg19:22:41368591-41368612:+] 0.7202 128 0 -8.87 -0.1926 MIMAT0003253 hsa-miR-587 9978 RBX1 cacugaguaguggaUACCUUu |||||| uaauuacaaauuggAUGGAAc 2 8 67 87 [hg19:22:41368559-41368579:+] 0.7202 120 6 -8.48 -0.1647 MIMAT0004805 hsa-miR-616 9978 RBX1 gacgaguUUGGGAGGUUACUGa | :| |::|||||| uuuuguuAUUCAUUUAAUGACu 2 16 30 51 [hg19:22:41368522-41368543:+] 0.7202 135 6 -15.36 -0.2358 MIMAT0003331 hsa-miR-655 9978 RBX1 uuucuccaAUUGGU---ACAUAAua ||:||| |||||| uguuucugUAGCCAUAUUGUAUUcu 3 15 121 145 [hg19:22:41368613-41368637:+] 0.7202 129 0 -9.02 -0.1158 MIMAT0005791 hsa-miR-1264 9978 RBX1 uuguccacgaguUUAUUCUGAAc :| ||||||| ------------GAAAAGACUUc 2 12 1 11 [hg19:22:41368493-41368503:+] 0.7202 143 7 -6.54 -0.4918 MIMAT0005791 hsa-miR-1264 9978 RBX1 uuguCCACGAGUUUAUU-CUGAAc | | :||| ||| ||||| uuuuGUUAUUCAUUUAAUGACUUu 2 20 30 53 [hg19:22:41368522-41368545:+] 0.7202 123 0 -9.23 -1.1118 MIMAT0005795 hsa-miR-1323 9978 RBX1 ucuuuuacggggaguCAAAACu |||||| ccaucaagcuuaauuGUUUUGu 2 8 14 35 [hg19:22:41368506-41368527:+] 0.7202 120 6 -9.49 -0.1308 MIMAT0004185 hsa-miR-802 9978 RBX1 ugUUCCUACUUA-GAAACAAUGAc ||| | | | :|||||||:| ucAAGCUUAAUUGUUUUGUUAUUc 2 22 17 40 [hg19:22:41368509-41368532:+] 0.7202 144 0 -11.94 -0.1600 MIMAT0004185 hsa-miR-802 9978 RBX1 uguuccUACUUAGA---A--ACAAUGac |||| |:| | |||||| cauuuaAUGACUUUCCCUGCUGUUACcu 3 18 40 67 [hg19:22:41368532-41368559:+] 0.7202 123 0 -7.25 -0.1891 MIMAT0010364 hsa-miR-761 9978 RBX1 acacAGUCAAAGUGGGACGACg | | ||| |||||||| uuaaUGACUUU--CCCUGCUGu 2 19 43 62 [hg19:22:41368535-41368554:+] 0.7202 151 7 -17.17 -1.2329 MIMAT0004901 hsa-miR-298 9978 RBX1 acCCU--CUUGG-AGGGACGAAGACGa ||| ||||: | ::| :|||||| uuGGAUGGAACUGUGUUUUUUUCUGCu 2 23 77 103 [hg19:22:41368569-41368595:+] 0.7202 144 6 -20.00 -0.3475 MIMAT0004972 hsa-miR-922 9978 RBX1 cugcauCAGGAUAAGAGACGAcg || :| ||:|||||| ggaacuGUGUUUUUUUCUGCUuu 3 18 83 105 [hg19:22:41368575-41368597:+] 0.7202 141 0 -14.62 -0.2223 MIMAT0004972 hsa-miR-922 9978 RBX1 cugcaucagGAUAAGAGACGACg || ||| |||||| auuuaaugaCU-UUCCCUGCUGu 2 15 41 62 [hg19:22:41368533-41368554:+] 0.7202 124 6 -13.71 -0.2742 MIMAT0005871 hsa-miR-1207-5p 9978 RBX1 ggggagggUCGGAGGGACGGu | ::|||||||: auuuaaugACUUUCCCUGCUg 2 14 41 61 [hg19:22:41368533-41368553:+] 0.7202 133 0 -15.42 -0.4233 MIMAT0005874 hsa-miR-548e 9978 RBX1 acguuuuCAUCAGAGUCAAAaa || |:||||||| cugcuuuGUUUUUUCAGUUUgc 3 16 99 120 [hg19:22:41368591-41368612:+] 0.7202 135 0 -12.12 -0.1944 MIMAT0005895 hsa-miR-548f 9978 RBX1 uuuuCAUUAAUGUCAAAaa || || |||||| cuuuGUUUUUUCAGUUUgc 3 16 102 120 [hg19:22:41368594-41368612:+] 0.7202 131 0 -5.68 -0.1944 MIMAT0005912 hsa-miR-548g 9978 RBX1 cauguuuuCAUUAAUGUCAAAa || || |||||| ucugcuuuGUUUUUUCAGUUUg 2 15 98 119 [hg19:22:41368590-41368611:+] 0.7202 122 6 -6.99 -0.2153 MIMAT0005919 hsa-miR-548o 9978 RBX1 cguuuucauugacguCAAAACc |||||| ccaucaagcuuaauuGUUUUGu 2 8 14 35 [hg19:22:41368506-41368527:+] 0.7202 120 6 -7.93 -0.1295 MIMAT0005923 hsa-miR-1269 9978 RBX1 ggucaucgugccgagUCAGGUc |||||| uucugugucaaauaaAGUCCAg 2 8 142 163 [hg19:22:41368634-41368655:+] 0.7202 120 6 -17.57 -0.3673 MIMAT0005934 hsa-miR-548p 9978 RBX1 uuucaUUGACGUCA-AAAACGAu |:|| | | |||||:| caucaAGCUUAAUUGUUUUGUUa 2 18 15 37 [hg19:22:41368507-41368529:+] 0.7202 132 0 -8.93 -0.1012 MIMAT0005934 hsa-miR-548p 9978 RBX1 uuucauugacgucaaAAACGAu |||||| gcuuuguuuuuucagUUUGCUg 2 8 101 122 [hg19:22:41368593-41368614:+] 0.7202 120 6 -11.42 -0.2843 MIMAT0005948 hsa-miR-664* 9978 RBX1 uagguuaguaAAAGGGAUCGGUca ||||: |||||| caguuugcugUUUCUGUAGCCAua 3 15 113 136 [hg19:22:41368605-41368628:+] 0.7202 138 0 -15.15 -0.2258 MIMAT0007883 hsa-miR-1909 9978 RBX1 gccacucgugggccGGGGACGc :|||||| ucauuuaaugacuuUCCCUGCu 2 9 39 60 [hg19:22:41368531-41368552:+] 0.7202 124 6 -15.50 -0.2982 MIMAT0009979 hsa-miR-2054 9978 RBX1 uuauuuaauuuaaauaUAAUGUc |||||| ucccugcuguuaccuaAUUACAa 2 8 53 75 [hg19:22:41368545-41368567:+] 0.7202 120 6 -3.16 -0.2367 MIMAT0011778 hsa-miR-2278 9978 RBX1 gguccguuguguguGACGAGAg |||||:| aacuguguuuuuuuCUGCUUUg 2 9 85 106 [hg19:22:41368577-41368598:+] 0.7202 124 0 -9.38 -0.1873 MIMAT0014982 hsa-miR-3120 9978 RBX1 acggACAGAUGU-GAACGACAc | |:| || :||||||| uuugUUUUUUCAGUUUGCUGUu 2 18 103 124 [hg19:22:41368595-41368616:+] 0.7202 152 7 -15.95 -1.2596 MIMAT0014982 hsa-miR-3120 9978 RBX1 acggACAGAUGUGAACGACAc || || : | |||||| uuaaUGACUUUCCCUGCUGUu 2 18 43 63 [hg19:22:41368535-41368555:+] 0.7202 125 6 -8.18 -0.1305 MIMAT0014999 hsa-miR-378b 9978 RBX1 aagacggaggUUCAGGUCa |||||||| gugucaaauaAAGUCCAGu 2 10 146 164 [hg19:22:41368638-41368656:+] 0.7202 145 7 -17.94 -1.2967 MIMAT0015000 hsa-miR-3134 9978 RBX1 uuauacaucagaaaauAGGUAGu |||||| ----gaaaagacuucuUCCAUCa 2 8 1 19 [hg19:22:41368493-41368511:+] 0.7202 120 6 -12.59 -0.2870 MIMAT0015020 hsa-miR-548v 9978 RBX1 accacguuuuCAUUGACAUCGa || ||||||| ucaguuugcuGUUUCUGUAGCc 2 13 112 133 [hg19:22:41368604-41368625:+] 0.7202 144 7 -14.93 -1.2602 MIMAT0015021 hsa-miR-3148 9978 RBX1 uucgugugugguCAAAAAAGgu |||||||| uuuuucugcuuuGUUUUUUCag 3 11 94 115 [hg19:22:41368586-41368607:+] 0.7202 130 0 -7.51 -0.1391 MIMAT0015026 hsa-miR-3153 9978 RBX1 uuUACAG-GGAUGAGCGAAAGGGg || || ::|| | ||||||| uuAU-UCAUUUAAUGACUUUCCCu 2 22 35 57 [hg19:22:41368527-41368549:+] 0.7202 150 7 -14.07 -1.2524 MIMAT0015065 hsa-miR-3185 9978 RBX1 ggcgucuggcuggCGGAAGAAGa | ||||||| --------gaaaaGACUUCUUCc 2 11 1 15 [hg19:22:41368493-41368507:+] 0.7202 142 7 -12.92 -0.3454 MIMAT0015066 hsa-miR-3065-5p 9978 RBX1 aggUCGUAGUCACUAAAACAAcu ||| |:| | :||||||| ucaAGC-UUAAUUGUUUUGUUau 3 21 17 38 [hg19:22:41368509-41368530:+] 0.7202 142 0 -7.58 -0.1972 MIMAT0015073 hsa-miR-3190-5p 9978 RBX1 agagaccggCAGAUGGAAGGUGu | || :||||||: ----gaaaaGACU-UCUUCCAUc 2 15 1 18 [hg19:22:41368493-41368510:+] 0.7202 128 0 -11.18 -0.1624 MIMAT0015081 hsa-miR-548x 9978 RBX1 acUUUCAUUAACGUCAAAAAu :| | || || |||||| ugGAUGGAACUG-UGUUUUUu 2 20 78 97 [hg19:22:41368570-41368589:+] 0.7202 121 6 -6.97 -0.1479 MIMAT0015081 hsa-miR-548x 9978 RBX1 acuuucauuaacguCAAAAAu |||||| uuuuuuucugcuuuGUUUUUu 2 8 92 112 [hg19:22:41368584-41368604:+] 0.7202 120 6 -5.13 -0.1693 MIMAT0015088 hsa-miR-514b-3p 9978 RBX1 aggugagugucucCACAGUUa ||||||| cauauuguauucuGUGUCAAa 2 9 133 153 [hg19:22:41368625-41368645:+] 0.7202 140 7 -10.59 -1.3201 MIMAT0016847 hsa-miR-378c 9978 RBX1 ggUGAGA-AGACUGAGGUUCAGGUCa |:||| | | | : |||||||| guAUUCUGUGUCAAAUAAAGUCCAGu 2 24 139 164 [hg19:22:41368631-41368656:+] 0.7202 158 7 -21.76 -1.2952 MIMAT0016900 hsa-miR-4270 9978 RBX1 cgGGAGGGGACU--GAGGGACu | |:: ||| :|||||| uuCAUUUAAUGACUUUCCCUGc 2 19 38 59 [hg19:22:41368530-41368551:+] 0.7202 129 6 -16.68 -0.2646 MIMAT0016905 hsa-miR-4275 9978 RBX1 uuucuucaccAUUAACc |||||| ccaucaagcuUAAUUGu 2 8 14 30 [hg19:22:41368506-41368522:+] 0.7202 120 6 -2.84 -0.4863 MIMAT0016908 hsa-miR-4277 9978 RBX1 cacaugacACGAGUCUUGACg || ::|||||| uuacaaauUGGAUGGAACUGu 2 14 70 90 [hg19:22:41368562-41368582:+] 0.7202 129 6 -12.46 -0.2130 MIMAT0016922 hsa-miR-4291 9978 RBX1 ucGACAAGGACGACuu || | ||||||| gaCUUUCCCUGCUGuu 3 15 48 63 [hg19:22:41368540-41368555:+] 0.7202 134 0 -14.11 -0.1136 MIMAT0000084 hsa-miR-27a 9978 RBX1 cgccUUGAAUCGG---UGACACuu || ||:| : |||||| uuacAAAUUGGAUGGAACUGUGuu 3 18 70 93 [hg19:22:41368562-41368585:+] 0.7202 124 0 -14.40 -0.2047 MIMAT0000095 hsa-miR-96 9978 RBX1 ucGUUUUUACACGA-UCACGGUUu | | | ||| :| |||:||| agCCAUAUUGUAUUCUGUGUCAAa 2 22 130 153 [hg19:22:41368622-41368645:+] 0.7202 136 0 -13.38 -0.1441 MIMAT0000250 hsa-miR-139-5p 9978 RBX1 gaccucugugcacguGACAUCu |||||| uucaguuugcuguuuCUGUAGc 2 8 111 132 [hg19:22:41368603-41368624:+] 0.7202 120 6 -11.32 -0.2346 MIMAT0000252 hsa-miR-7 9978 RBX1 uguuguuuuagugaucAGAAGGu |||||| -------gaaaagacuUCUUCCa 2 8 1 16 [hg19:22:41368493-41368508:+] 0.7202 120 6 -12.22 -0.4974 MIMAT0000271 hsa-miR-214 9978 RBX1 ugacggACAGACACGGACGACa || || | ||||||| auuuaaUGACUUUCCCUGCUGu 2 17 41 62 [hg19:22:41368533-41368554:+] 0.7202 156 7 -15.43 -1.2329 MIMAT0000278 hsa-miR-221 9978 RBX1 cuuugggucgucuguuACAUCGa |||||| uucaguuugcuguuucUGUAGCc 2 8 111 133 [hg19:22:41368603-41368625:+] 0.7202 120 6 -12.10 -0.3763 MIMAT0000279 hsa-miR-222 9978 RBX1 ugggucaucggucuACAUCGa |||||| caguuugcuguuucUGUAGCc 2 8 113 133 [hg19:22:41368605-41368625:+] 0.7202 120 6 -12.50 -0.3793 MIMAT0000281 hsa-miR-224 9978 RBX1 uugccUUGGU-GAUCACUGAAc | :|| :|| |||||| uuguuAUUCAUUUAAUGACUUu 2 17 32 53 [hg19:22:41368524-41368545:+] 0.7202 123 6 -9.44 -0.1281 MIMAT0000419 hsa-miR-27b 9978 RBX1 cgUCUUGAAUCGG---UGACACuu | || ||:| : |||||| uuACAAAUUGGAUGGAACUGUGuu 3 20 70 93 [hg19:22:41368562-41368585:+] 0.7202 126 0 -11.75 -0.2047 MIMAT0000424 hsa-miR-128 9978 RBX1 uuucucuggccaagUGACACu |||||| acaaauuggauggaACUGUGu 2 8 72 92 [hg19:22:41368564-41368584:+] 0.7202 120 6 -14.35 -0.1872 MIMAT0000428 hsa-miR-135a 9978 RBX1 aguguauccuuauuuuUCGGUAu |||||| aguuugcuguuucuguAGCCAUa 2 8 114 136 [hg19:22:41368606-41368628:+] 0.7202 120 6 -9.29 -0.2662 MIMAT0000460 hsa-miR-194 9978 RBX1 agguguaccucaACGACAAUGu ||||||||| aaugacuuucccUGCUGUUACc 2 11 45 66 [hg19:22:41368537-41368558:+] 0.7202 150 7 -13.47 -1.1226 MIMAT0000720 hsa-miR-376c 9978 RBX1 ugcaccuUAA-AGGAGAUACAa ||| | :|||:||| uagccauAUUGUAUUCUGUGUc 2 15 129 150 [hg19:22:41368621-41368642:+] 0.7202 133 0 -9.88 -0.1710 MIMAT0000730 hsa-miR-377 9978 RBX1 uguuuucAACGGAA-ACACACUa |||: || ||||| | agccauaUUGUAUUCUGUGUCAa 2 16 130 152 [hg19:22:41368622-41368644:+] 0.7202 122 0 -6.41 -0.2045 MIMAT0000732 hsa-miR-378 9978 RBX1 ggAAGACUGAG----GUUCAGGUCa ||||| || |||||||| uaUUCUGUGUCAAAUAAAGUCCAGu 2 20 140 164 [hg19:22:41368632-41368656:+] 0.7202 150 7 -21.72 -1.2952 MIMAT0000758 hsa-miR-135b 9978 RBX1 aguguauccuuacuuuUCGGUAu |||||| aguuugcuguuucuguAGCCAUa 2 8 114 136 [hg19:22:41368606-41368628:+] 0.7202 120 6 -10.61 -0.2662 MIMAT0001339 hsa-miR-422a 9978 RBX1 cggAAGAC-UGG---GAUUCAGGUCa ||||| ::| : |||||||| guaUUCUGUGUCAAAUAAAGUCCAGu 2 20 139 164 [hg19:22:41368631-41368656:+] 0.7202 149 7 -20.54 -1.2952 MIMAT0003393 hsa-miR-425 9978 RBX1 aguugcccuCACUAG-CACAGUaa || || |||||| agccauauuGUAUUCUGUGUCAaa 3 15 130 153 [hg19:22:41368622-41368645:+] 0.7202 125 0 -9.63 -0.4200 MIMAT0002816 hsa-miR-494 9978 RBX1 cuccAAAGGGCACA-UACAAAGu |||:| || | |||||| uguuUUUUCAGUUUGCUGUUUCu 2 19 105 127 [hg19:22:41368597-41368619:+] 0.7202 129 6 -9.60 -0.1433 MIMAT0002817 hsa-miR-495 9978 RBX1 uucuucacgugguacAAACAAa |||||| aucaagcuuaauuguUUUGUUa 2 8 16 37 [hg19:22:41368508-41368529:+] 0.7202 120 6 -5.26 -0.2683 MIMAT0002817 hsa-miR-495 9978 RBX1 uucuucacgugguacAAACAAa |||||| uguguuuuuuucugcUUUGUUu 2 8 88 109 [hg19:22:41368580-41368601:+] 0.7202 120 6 -8.82 -0.1793 MIMAT0005796 hsa-miR-1271 9978 RBX1 acUCACGAACGAUCCACGGUUc | ||: | || |||:||| auAUUGUAUUCU--GUGUCAAa 2 21 134 153 [hg19:22:41368626-41368645:+] 0.7202 133 0 -8.00 -0.1376

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G003406 MO000029885 RBX1 Homo sapiens 9978

DNA & RNA Element - miRWalk Gene Name miRNAname Entrez ID Pathways RBX1 hsa-miR-92a-3p 9978 hsa03420_Nucleotide excision repair RBX1 hsa-miR-92a-3p 9978 hsa04110_Cell cycle RBX1 hsa-miR-92a-3p 9978 hsa04114_Oocyte meiosis RBX1 hsa-miR-92a-3p 9978 hsa04120_Ubiquitin mediated proteolysis RBX1 hsa-miR-92a-3p 9978 hsa04310_Wnt signaling pathway RBX1 hsa-miR-92a-3p 9978 hsa04350_TGF beta signaling pathway RBX1 hsa-miR-92a-3p 9978 hsa05200_Pathways in cancer RBX1 hsa-miR-92a-3p 9978 hsa05211_Renal cell carcinoma

DNA & RNA Element - TargetScan Gene Name UTR Region Start UTR Region End AIR Total Normalized 3P-seq-tags & Pseudocounts Strand hg19_chromosome Genome Start Genome End RBX1; RNF75; ROC1 1 90 100 3051.721 + chr22 41368492 41368582 RBX1; RNF75; ROC1 91 147 99.244 3051.721 + chr22 41368582 41368639 RBX1; RNF75; ROC1 148 148 99.219 3051.721 + chr22 41368639 41368640 RBX1; RNF75; ROC1 149 172 99.003 3051.721 + chr22 41368640 41368664 RBX1; RNF75; ROC1 173 178 79.79 3051.721 + chr22 41368664 41368670 RBX1; RNF75; ROC1 179 241 0.376 3051.721 + chr22 41368670 41368733 RBX1; RNF75; ROC1 242 821 0.164 3051.721 + chr22 41368733 41369313

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile RBX1 hsa-miR-378c beg:153 end:165 pic:3' GGTGAGAAGACTGAGGTTCAGGTCA 5'& ||||||||| &5' ----------------AAGTCCAGT 3' RBX1 hsa-miR-378 beg:153 end:165 pic:3' GGAAGACTGAGGTTCAGGTCA 5'& ||||||||| &5' ------------AAGTCCAGT 3' RBX1 hsa-miR-422a beg:153 end:165 pic:3' CGGAAGACTGGGATTCAGGTCA 5'& ||||||||| &5' -------------AAGTCCAGT 3' RBX1 hsa-miR-214 beg:44 end:63 pic:3' TGACGGACAGACACGGACGACA 5'& || || || |||||||| &5' --TGACTTTC----CCTGCTGT 3' RBX1 hsa-miR-761 beg:51 end:63 pic:3' ACACAGTCAAAGTGGGACGACG 5'& ||||||||. &5' -------------CCCTGCTGT 3' RBX1 hsa-miR-548v beg:115 end:133 pic:3' ACCACGTTTTCATTGACATCGA 5'& ||| || ||||||| &5' ---TGCT---GTTTCTGTAGC- 3' RBX1 hsv1-miR-H1 beg:6 end:19 pic:3' AGGTGAAGGGCAGGAAGGTAG 5'& |.|||||||| &5' -----------TTCTTCCATC 3' RBX1 ebv-miR-BART19-3p beg:137 end:159 pic:3' TCGTAAGGGTTC-GTTTGTTTT 5'& |.||||. | ||||.|||. &5' -GTATTCTGT-GTCAAATAAAG 3' RBX1 hsa-miR-514b-3p beg:137 end:153 pic:3' AGGTGAGTGTCTCCACAGTTA 5'& .|.|| ||||||| &5' --TATTCT-----GTGTCAA- 3' RBX1 hsa-miR-514 beg:137 end:153 pic:3' AGATGAGTGTCTTCACAGTTA 5'& ||.|| ||||||| &5' --TATTCT-----GTGTCAA- 3' RBX1 hsa-miR-100star beg:4 end:25 pic:3' GTATGGATATCTATGTTCGAAC 5'& ||.| ||||||| &5' ---ACTTCTTCCATCAAGCTT- 3' RBX1 hsa-miR-1243 beg:146 end:166 pic:3' GTGAGGATATTAACTAGGTCAA 5'& || |||| .||||||| &5' ---TCAAATAAA--GTCCAGTT 3' RBX1 hsa-miR-1289 beg:152 end:173 pic:3' TTTTACGTCTAAGGACCTGAGGT 5'& |||.| ||| .||||.||. &5' AAAGTCCAG----TTGGATTCT- 3' RBX1 hsa-miR-1290 beg:50 end:72 pic:3' AGGGAC--TAGGTTTTTAGGT 5'& |||||| .|. |||. &5' TCCCTGCTGTTACCTAATT-- 3' RBX1 hsa-miR-142-5p beg:92 end:108 pic:3' TCATCACGAAAGATGAAATAC 5'& .|||||.||||.| &5' -------TTTTCTGCTTTGT- 3' RBX1 hsa-miR-2277 beg:110 end:125 pic:3' CTCGGTCCGTCCCGCGACAGT 5'& ||| .|||||. &5' --------CAGTTTGCTGTT- 3' RBX1 hsa-miR-3120 beg:103 end:124 pic:3' ACGGACAGAT--GT-GAACGACAC 5'& .|||.| || .||||||| &5' ---TTGTTTTTTCAGTTTGCTGT- 3' RBX1 hsa-miR-3134 beg:2 end:20 pic:3' TTATACATCAGAAAATAGGTAGT 5'& || ||| ||||||| &5' -------AGACTTCT-TCCATCA 3' RBX1 hsa-miR-3136 beg:42 end:65 pic:3' TTACTGGGATGGATAAGTCAGTC 5'& ||||||..| |||. ||.| &5' AATGACTTTCCCTGCT--GTTA- 3' RBX1 hsa-miR-3190-5p beg:5 end:18 pic:3' AGAGACCGGCAGATGGAAGGTGT 5'& || .||||||. &5' -----------CT-TCTTCCAT- 3' RBX1 hsa-miR-330-3p beg:84 end:108 pic:3' AGAGACGTCCGGCACACGAAACG 5'& || ||. |||||||. &5' -CTGTGTTTTTTTC-TGCTTTGT 3' RBX1 hsa-miR-330-3p beg:15 end:36 pic:3' AGAGACGTCCGGCAC-ACGAAACG 5'& || ||. ||.||||. &5' ------CAAGCTTAATTGTTTTGT 3' RBX1 hsa-miR-4251 beg:98 end:116 pic:3' AACCGGG--AAAAGAGTCC 5'& ||.. ||||.|||| &5' ---GCTTTGTTTTTTCAG- 3' RBX1 hsa-miR-4261 beg:79 end:98 pic:3' ACCCAGGGACAAAGGA 5'& ||| |. |||||..| &5' TGGAACTGTGTTTTTT 3' RBX1 hsa-miR-4291 beg:116 end:130 pic:3' TCGACAAGGACGACTT 5'& ||||||.|||. &5' -GCTGTTTCTGT---- 3' RBX1 hsa-miR-545 beg:112 end:123 pic:3' CGTGTGTTATTTACAAACGACT 5'& |||||||| &5' -------------GTTTGCTG- 3' RBX1 hsa-miR-584 beg:119 end:137 pic:3' GAGTCAGGGTCCGTTTGGTATT 5'& || | |. |.||||| &5' ----GTTTCT-GT-AGCCATA- 3' RBX1 hsa-miR-7 beg:0 end:17 pic:3' TGTTGTTTTAGTGATCAGAAGGT 5'& .||| ||| ||||||| &5' -----GAAAAGACT--TCTTCCA 3' RBX1 hsa-miR-761 beg:102 end:124 pic:3' ACACAGTCAAAGTGGGACGACG 5'& |||. ||||| ..|||||. &5' --TGTTT-TTTCAGTTTGCTGT 3' RBX1 kshv-miR-K12-4-3p beg:116 end:147 pic:3' AGTCGATC-------CGGAGT--CATAAGAT 5'& |||. ||| |||||||. &5' ---GCTGTTTCTGTAGCCATATTGTATTCTG 3' RBX1 mcv-miR-M1-5p beg:2 end:17 pic:3' TCACATGGATCTTTAAGAAGGT 5'& ||| |||||||| &5' ---------AGAC-TTCTTCCA 3'

DNA & RNA Element - miRNAMap Gene Name Mature miRNA Target Start Target End miRNA 3-5 Alignment Target 5-3 RBX1; RNF75; ROC1 hsa-miR-214 55 62 GACGGACAGACAC-----------------------GGACGACA ||:| :||| |||||||| A-GCUUAAUUGUUUUGUUAUUCAUUUAAUGACUUUCCCUGCUGUU RBX1; RNF75; ROC1 hsa-miR-330 100 107 AGA---------GACGU-CC--GGCAC--------ACGAAACG :|| | || |:||| |||||||: CCUAAUUACAAAUUGGAUGGAACUGUGUUUUUUUCUGCUUUGUU RBX1; RNF75; ROC1 hsa-miR-422a 156 163 C---------CGG--------AAGACU--GG--GAUUCAGGUC ||| ||||| | : |||||||| UGUUUCUGUAGCCAUAUUGUAUUCUGUGUCAAAUAAAGUCCAGU RBX1; RNF75; ROC1 hsa-miR-422b 156 163 C---------CGG--------AAGACUGAGG----UUCAGGUC ||| ||||| || |||||||| UGUUUCUGUAGCCAUAUUGUAUUCUGUGUCAAAUAAAGUCCAGU RBX1; RNF75; ROC1 hsa-miR-514 146 153 G----------------------------AUGAGUGUCUUCACAGUUA ||:|| ||||||| UUCAGUUUGCUGUUUCUGUAGCCAUAUUGUAUUCU-----GUGUCAAA RBX1; RNF75; ROC1 hsa-miR-127 147 176 UCGGU-----UCGAGUCUGCCUA-GGCU- |:|| ||: ||| |||| |:|: UGUCAAAUAAAGUCCAGUUGGAUUCUGGA RBX1; RNF75; ROC1 hsa-miR-181d 54 85 UUGGGUGGC----------UGUUGUUACUUACAA ||::|:| |||| ||:||| -CCCUGCUGUUACCUAAUUACAAAU-UGGAUGG- RBX1; RNF75; ROC1 hsa-miR-182* 161 181 AUCAACCGUUCAGAUCUUGGU- |||||| |||:|||| : CAGUUGGAU--UCUGGAACGGA RBX1; RNF75; ROC1 hsa-miR-214 98 125 -GACG-GACAGACA---CGGACGACA- |||| :|||:| |::|||||| UCUGCUUUGUUUUUUCAGUUUGCUGUU RBX1; RNF75; ROC1 hsa-miR-24 104 136 GACAAG-------GACGACUU-GAC-UCGGU- ||||: :||||| ||| ||||| UUGUUUUUUCAGUUUGCUGUUUCUGUAGCCAU RBX1; RNF75; ROC1 hsa-miR-324-5p 156 185 -UGUGGUUAC---GGGAUCC--CCUACGC | |||:| ::||:| |||||| AAGUCCAGUUGGAUUCUGGAACGGAUGCU RBX1; RNF75; ROC1 hsa-miR-330 76 109 AGAGACGU-CC--GGCACA--------CGAAACG- :|| | || |:|||| ||||||: --AUUGGAUGGAACUGUGUUUUUUUCUGCUUUGUU RBX1; RNF75; ROC1 hsa-miR-338 151 177 AGUUGUUUUAGUGA---CUACGACCU- ||:|||:|| ||| ||||| -AAAUAAAGUCCAGUUGGAUUCUGGAA RBX1; RNF75; ROC1 hsa-miR-422a 130 165 CCGG--------AAGACUGGGA----UUCAGGUC- ||| ||||| :| |||||||| AGCCAUAUUGUAUUCUGUGUCAAAUAAAGUCCAGU RBX1; RNF75; ROC1 hsa-miR-422b 130 165 CCGG--------AAGACUGAGG----UUCAGGUC- ||| ||||| || |||||||| AGCCAUAUUGUAUUCUGUGUCAAAUAAAGUCCAGU RBX1; RNF75; ROC1 hsa-miR-451 160 181 UUUGAGUCAUU-----ACCAUUGCCAAA |||| ||| ||||| ----CCAGUUGGAUUCUGG-AACGGA-- RBX1; RNF75; ROC1 hsa-miR-513 44 63 UAUUUACUGUGGAGGGAC-ACUU |||||| ::|||||| || --UAAUGAC-UUUCCCUGCUGU- RBX1; RNF75; ROC1 hsa-miR-514 139 154 GAUGAGUGUCUUCACAGUUA ||:|| ||||||| GUAUUCU-----GUGUCAAA RBX1; RNF75; ROC1 hsa-miR-519a 162 188 -CAUUGUGAGAUUUU-CCUACGUGAAA || : |:|||::|| |||||| || AGUUGGAUUCUGGAACGGAUGCUCUC- RBX1; RNF75; ROC1 hsa-miR-519b 168 188 UUUGGAGAUUUU-CCUACGUGAAA :|||::|| |||||| || ---AUUCUGGAACGGAUGCUCUC- RBX1; RNF75; ROC1 hsa-miR-520a* 172 191 -UCUU-UC-AUGAAGGGAGACCUC :||| :| |:|| |:|||| UGGAACGGAUGCU-CUCUCU---- RBX1; RNF75; ROC1 hsa-miR-525 145 177 UCUUUCACG--------UAGG-------GAGACCUC |||: :||| :|||||| ----UGUGUCAAAUAAAGUCCAGUUGGAUUCUGGAA RBX1; RNF75; ROC1 hsa-miR-564 114 135 -CGGACGACUGUGGCA-CGGA |::||||| |:|| ||| AGUUUGCUGUUUCUGUAGCCA RBX1; RNF75; ROC1 hsa-miR-582 74 93 UCAUUGACCAACUUGUUGACAUU ||:||| ||:| |||||: --AAAUUGGAUGGA--ACUGUGU RBX1; RNF75; ROC1 hsa-miR-589 82 103 AGACCCUUGGC-CGUAAACAAGACU |||||:| |: ||| ||||| ---UGGAACUGUGUUUUU-UUCUGC RBX1; RNF75; ROC1 hsa-miR-602 118 152 CCCGGCGUCGACAGCGG-----------GCACAG- ||:|: |||| ||| :||||| -UGCUGUUUCUGUAGCCAUAUUGUAUUCUGUGUCA RBX1; RNF75; ROC1 hsa-miR-604 117 135 CAGGACUUAAGGCGUCGGA | ||| |||:|:|||| UUGCUGU-UUCUGUAGCCA RBX1; RNF75; ROC1 hsa-miR-634 157 176 -CAGGUUUCAACCCCACGACCAA |||| |||||| |||| AGUCC--AGUUGGAUU-CUGGA- RBX1; RNF75; ROC1 hsa-miR-127 152 173 ucggUUCGAGUCUGCCUAGGcu |||: ||| :||||:| aataAAGTCCAGTTGGATTCtg RBX1; RNF75; ROC1 hsa-miR-181d 63 85 uUGGGUGGCUGUUGUUACUUACaa |||:| : |||| | ||:||| tACCTAATTACAA-ATTGGATGga RBX1; RNF75; ROC1 hsa-miR-214 42 62 gacggACAGACACGGACGACA || || | |||||||| tttaaTGACTTTCCCTGCTGT RBX1; RNF75; ROC1 hsa-miR-214 99 123 GACG-GACAGACA---CGGACGACA |||| :|||:| | |::|||||| CTGCTTTGTTTTTTCAGTTTGCTGT RBX1; RNF75; ROC1 hsa-miR-24 113 134 GACAAGGACGAC-UUGAC-UCGGU | ||| ||||| ||| ||||| CAGTT--TGCTGTTTCTGTAGCCA RBX1; RNF75; ROC1 hsa-miR-324-5p 157 184 uguGGUUA--C-GGGAUC--CCCUACGc |||:| | ::||:| |||||| agtCCAGTTGGATTCTGGAACGGATGCt RBX1; RNF75; ROC1 hsa-miR-330 74 107 agagACGU-CC--GGCAC--------ACGAAACg || | || |:||| ||||||| aaatTGGATGGAACTGTGTTTTTTTCTGCTTTGt RBX1; RNF75; ROC1 hsa-miR-338 149 175 AG-UUGUUUUA-GUGA--CUACGACCU || ||:|||:| || | ||| ||||| TCAAATAAAGTCCAGTTGGATTCTGGA RBX1; RNF75; ROC1 hsa-miR-422a 138 163 cCGGAAGACUGGG---A-UUCAGGUC |: ||||| :| | |||||||| tGTATTCTGTGTCAAATAAAGTCCAG RBX1; RNF75; ROC1 hsa-miR-422b 138 163 cCGGAAGACUGAG----GUUCAGGUC |: ||||| || |||||||| tGTATTCTGTGTCAAATAAAGTCCAG RBX1; RNF75; ROC1 hsa-miR-451 156 182 UUUGAGUCA--UU---ACCAUUGCCAAa ||:: |||| :| ||| ||||| | AAGTCCAGTTGGATTCTGG-AACGGATg RBX1; RNF75; ROC1 hsa-miR-513 42 63 uAUUUACUGUGGAGGGAC-ACuu | |||||| ::|||||| || tTTAATGAC-TTTCCCTGCTGtt RBX1; RNF75; ROC1 hsa-miR-519a 163 188 CAUUGUGAGAUUUU-CCUACGUGAaa || : |:|||::|| |||||| || GTTGGATTCTGGAACGGATGCTCTct RBX1; RNF75; ROC1 hsa-miR-519b 165 188 uuuggAGAUUUU-CCUACGUGAaa |||::|| |||||| || tggatTCTGGAACGGATGCTCTct RBX1; RNF75; ROC1 hsa-miR-520a* 153 176 UCUUUCAUG--AA-GGGAGACCUc | ||||| | || :|||||| ATAAAGTCCAGTTGGATTCTGGAa RBX1; RNF75; ROC1 hsa-miR-525 153 176 UCUUUCACGUAGG---GAGACCUc | ||||| || :: :|||||| ATAAAGTCCAGTTGGATTCTGGAa RBX1; RNF75; ROC1 hsa-miR-564 115 134 CGGACGACUGUGGCA-CGGa |::||||| : |:|| ||| GTTTGCTGTTTCTGTAGCCa RBX1; RNF75; ROC1 hsa-miR-582 72 92 ucaUUGACCAACUUGUUGACAuu ||:||| ||: |||||| acaAATTGGATGG--AACTGTgt RBX1; RNF75; ROC1 hsa-miR-589 79 102 agacCCUUGGCCGUAAACAAGACu |||||:| ||| ||||| ggatGGAACTGTGTTTTTTTCTGc RBX1; RNF75; ROC1 hsa-miR-602 123 150 cccGGCGUCG-----ACAGCGGGCACAG |:|:||| ||| :|:||||| tttCTGTAGCCATATTGTATTCTGTGTC RBX1; RNF75; ROC1 hsa-miR-619 143 166 uGACCCGUGUUUG-UACAGGUCCAg ||| |: ||||: | |||||| | tCTGTGT-CAAATAAAGTCCAGTTg RBX1; RNF75; ROC1 hsa-miR-634 158 176 CAGGUUUCAACCCCACGACCaa |||| |||| || | |||| GTCC--AGTT-GGATTCTGGaa

DNA & RNA Element - miRcode Gene Name Type microRNA Seed Position Seed Type Total Cons% Tr Region RBX1 High_conserved miR-503 chr22:41347361 7-mer-m8 20 ncRNA RBX1 High_conserved miR-7/7ab chr22:41362567 7-mer-A1 24 ncRNA RBX1 High_conserved miR-7/7ab chr22:41368508 7-mer-A1 33 3pUTR, ncRNA RBX1 High_conserved miR-133abc chr22:41363510 7-mer-m8 16 ncRNA RBX1 High_conserved miR-9/9ab chr22:41363472 7-mer-A1 7 ncRNA RBX1 High_conserved miR-93/93a/105/106a/291a-3p/294/295/302abcde/372/373/428/519a/520be/520acd-3p/1378/1420ac chr22:41360325 7-mer-A1 11 ncRNA RBX1 High_conserved miR-93/93a/105/106a/291a-3p/294/295/302abcde/372/373/428/519a/520be/520acd-3p/1378/1420ac chr22:41362865 7-mer-m8 13 ncRNA RBX1 High_conserved miR-135ab/135a-5p chr22:41368628 7-mer-A1 40 3pUTR, ncRNA RBX1 High_conserved miR-141/200a chr22:41363029 7-mer-m8 16 ncRNA RBX1 High_conserved miR-150/5127 chr22:41362419 7-mer-A1 9 ncRNA RBX1 High_conserved miR-150/5127 chr22:41362736 8-mer 27 ncRNA RBX1 High_conserved miR-183 chr22:41349612 7-mer-m8 80 CDS, ncRNA RBX1 High_conserved miR-194 chr22:41360290 8-mer 20 ncRNA RBX1 High_conserved miR-194 chr22:41368558 7-mer-m8 40 3pUTR, ncRNA RBX1 High_conserved miR-1ab/206/613 chr22:41363523 8-mer 16 ncRNA RBX1 High_conserved miR-200bc/429/548a chr22:41360369 7-mer-m8 13 ncRNA RBX1 High_conserved miR-203 chr22:41362682 7-mer-m8 9 ncRNA RBX1 High_conserved miR-204/204b/211 chr22:41362561 7-mer-m8 16 ncRNA RBX1 High_conserved miR-205/205ab chr22:41362857 8-mer 13 ncRNA RBX1 High_conserved miR-208ab/208ab-3p chr22:41360335 7-mer-A1 29 ncRNA RBX1 High_conserved miR-210 chr22:41362889 7-mer-m8 11 ncRNA RBX1 High_conserved miR-214/761/3619-5p chr22:41368554 7-mer-m8 13 3pUTR, ncRNA RBX1 High_conserved miR-217 chr22:41349570 8-mer 64 CDS, ncRNA RBX1 High_conserved miR-22/22-3p chr22:41368908 7-mer-m8 16 3pUTR RBX1 High_conserved miR-23abc/23b-3p chr22:41368694 7-mer-A1 31 3pUTR RBX1 High_conserved miR-23abc/23b-3p chr22:41369112 7-mer-m8 11 3pUTR RBX1 High_conserved miR-24/24ab/24-3p chr22:41363762 7-mer-m8 18 ncRNA RBX1 High_conserved miR-27abc/27a-3p chr22:41363233 7-mer-A1 13 ncRNA RBX1 High_conserved miR-101/101ab chr22:41360103 7-mer-m8 13 CDS, ncRNA RBX1 High_conserved miR-101/101ab chr22:41369034 7-mer-m8 13 3pUTR RBX1 High_conserved miR-31 chr22:41363703 7-mer-m8 7 ncRNA RBX1 High_conserved miR-103a/107/107ab chr22:41362393 7-mer-A1 18 ncRNA RBX1 High_conserved miR-375 chr22:41368698 7-mer-A1 13 3pUTR RBX1 High_conserved miR-10abc/10a-5p chr22:41360295 8-mer 20 ncRNA RBX1 High_conserved miR-455-5p chr22:41363562 8-mer 11 ncRNA RBX1 High_conserved miR-129-5p/129ab-5p chr22:41362674 7-mer-A1 0 ncRNA RBX1 High_conserved miR-129-5p/129ab-5p chr22:41362962 7-mer-A1 16 ncRNA RBX1 High_conserved miR-499-5p chr22:41360335 7-mer-A1 29 ncRNA RBX1 Medium_conserved miR-542-3p chr22:41362304 7-mer-m8 29 ncRNA RBX1 Medium_conserved miR-542-3p chr22:41362580 7-mer-m8 13 ncRNA RBX1 Medium_conserved miR-544/544ab/544-3p chr22:41362919 7-mer-m8 7 ncRNA RBX1 Medium_conserved miR-590-3p chr22:41360302 7-mer-A1 20 ncRNA RBX1 Medium_conserved miR-873 chr22:41363578 7-mer-A1 13 ncRNA RBX1 Medium_conserved miR-875-5p chr22:41360243 7-mer-A1 27 ncRNA RBX1 Medium_conserved miR-224 chr22:41362361 7-mer-A1 11 ncRNA RBX1 Medium_conserved miR-28-5p/708/1407/1653/3139 chr22:41363371 7-mer-A1 9 ncRNA RBX1 Medium_conserved miR-320abcd/4429 chr22:41368748 7-mer-m8 29 3pUTR RBX1 Medium_conserved miR-329/329ab/362-3p chr22:41363857 7-mer-m8 53 CDS, ncRNA RBX1 Medium_conserved miR-335/335-5p chr22:41363213 7-mer-m8 20 ncRNA RBX1 Medium_conserved miR-374ab chr22:41360341 7-mer-A1 22 ncRNA RBX1 Medium_conserved miR-374ab chr22:41362704 7-mer-m8 9 ncRNA RBX1 Medium_conserved miR-377 chr22:41368893 7-mer-m8 16 3pUTR RBX1 Medium_conserved miR-378/422a/378bcdefhi chr22:41368656 7-mer-m8 24 3pUTR, ncRNA RBX1 Medium_conserved miR-379/1193-5p/3529 chr22:41362375 7-mer-A1 4 ncRNA RBX1 Medium_conserved miR-379/1193-5p/3529 chr22:41363344 7-mer-A1 11 ncRNA RBX1 Medium_conserved miR-384/384-3p chr22:41368496 8-mer 18 3pUTR, ncRNA RBX1 Medium_conserved miR-410/344de/344b-1-3p chr22:41362705 7-mer-A1 9 ncRNA RBX1 Medium_conserved miR-421 chr22:41363666 7-mer-A1 16 ncRNA RBX1 Medium_conserved miR-125a-3p/1554 chr22:41360286 7-mer-m8 20 ncRNA RBX1 Medium_conserved miR-125a-3p/1554 chr22:41362467 7-mer-A1 4 ncRNA RBX1 Medium_conserved miR-125a-3p/1554 chr22:41369244 7-mer-A1 11 3pUTR RBX1 Medium_conserved miR-433 chr22:41369253 7-mer-m8 9 3pUTR RBX1 Medium_conserved miR-495/1192 chr22:41360360 7-mer-A1 27 ncRNA RBX1 Medium_conserved miR-495/1192 chr22:41362797 7-mer-A1 13 ncRNA RBX1 Medium_conserved miR-495/1192 chr22:41368529 7-mer-A1 42 3pUTR, ncRNA RBX1 Medium_conserved miR-495/1192 chr22:41368767 7-mer-m8 27 3pUTR

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score RBX1 RAID00004777 hsa-miR-330-3p miRNA MIMAT0000751 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID00023179 hsa-miR-92a-3p miRNA MIMAT0000092 RBX1 mRNA 9978 CLASH 0.5483 RBX1 RAID00074284 hsa-miR-377-3p miRNA MIMAT0000730 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID00154718 hsa-miR-221-3p miRNA MIMAT0000278 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID00178292 hsa-miR-494-3p miRNA MIMAT0002816 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID00384219 hsa-miR-6510-5p miRNA MIMAT0025476 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID00487431 hsa-miR-378a-3p miRNA MIMAT0000732 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID00839719 hsa-miR-135b-5p miRNA MIMAT0000758 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6478 RBX1 RAID01016814 hsa-miR-1271-5p miRNA MIMAT0005796 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01049718 hsa-miR-96-5p miRNA MIMAT0000095 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01171978 hsa-miR-4513 miRNA MIMAT0019050 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID01268116 hsa-miR-135a-5p miRNA MIMAT0000428 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01323736 hsa-miR-376c-3p miRNA MIMAT0000720 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01393015 hsa-miR-514a-3p miRNA MIMAT0002883 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID01463344 hsa-miR-514b-3p miRNA MIMAT0015088 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID01597428 hsa-miR-6857-3p miRNA MIMAT0027615 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID01622803 hsa-miR-128-3p miRNA MIMAT0000424 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01673571 hsa-miR-3120-3p miRNA MIMAT0014982 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID01710943 hsa-miR-6875-3p miRNA MIMAT0027651 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID01807510 hsa-miR-4731-3p miRNA MIMAT0019854 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID01873227 hsa-miR-27b-3p miRNA MIMAT0000419 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01893545 hsa-miR-224-5p miRNA MIMAT0000281 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01895470 hsa-miR-27a-3p miRNA MIMAT0000084 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01944727 hsa-miR-214-3p miRNA MIMAT0000271 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID01958596 hsa-miR-188-3p miRNA MIMAT0004613 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID02144742 hsa-miR-4439 miRNA MIMAT0018957 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID02206275 hsa-miR-2276-5p miRNA MIMAT0026921 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID02260191 hsa-miR-422a miRNA MIMAT0001339 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID02458191 hsa-miR-4801 miRNA MIMAT0019980 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID02500870 hsa-miR-222-3p miRNA MIMAT0000279 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID02506261 hsa-miR-495-3p miRNA MIMAT0002817 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID02520289 hsa-miR-642a-5p miRNA MIMAT0003312 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID02545988 hsa-miR-100-3p miRNA MIMAT0004512 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID02559010 hsa-miR-194-5p miRNA MIMAT0000460 RBX1 mRNA 9978 Reporter Assay//FACS (fluorescence-activated cell sorting)//RT-PCR//Western Blot//CLIP-seq//Prediction 0.9937 RBX1 RAID02582440 hsa-miR-6892-3p miRNA MIMAT0027685 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID02656481 hsa-miR-5187-3p miRNA MIMAT0021118 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID03023015 hsa-miR-425-5p miRNA MIMAT0003393 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID03290675 hsa-miR-7-5p miRNA MIMAT0000252 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID03505774 hsa-miR-6855-3p miRNA MIMAT0027611 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID03528745 hsa-miR-5688 miRNA MIMAT0022479 RBX1 mRNA 9978 Prediction 0.1828 RBX1 RAID04001059 hsa-miR-3136-5p miRNA MIMAT0015003 RBX1 mRNA 9978 CLIP-seq 0.5483 RBX1 RAID04005301 hsa-miR-139-5p miRNA MIMAT0000250 RBX1 mRNA 9978 CLIP-seq//Prediction 0.6308 RBX1 RAID04676741 FENDRR lncRNA 400550 RBX1 protein 9978 Microarray//RNA-seq 0.6606