PTM - CPLM Gene Name UniProt ID Type Position Code EP300; P300 Q09472 Acetylation 291 K EP300; P300 Q09472 Acetylation 636 K EP300; P300 Q09472 Acetylation 977 K EP300; P300 Q09472 Acetylation 981 K EP300; P300 Q09472 Acetylation 1103 K EP300; P300 Q09472 Acetylation 1180 K EP300; P300 Q09472 Acetylation 1336 K EP300; P300 Q09472 Acetylation 1473 K EP300; P300 Q09472 Acetylation 1499 K EP300; P300 Q09472 Acetylation 1528 K EP300; P300 Q09472 Acetylation 1542 K EP300; P300 Q09472 Acetylation 1546 K EP300; P300 Q09472 Acetylation 1549 K EP300; P300 Q09472 Acetylation 1550 K EP300; P300 Q09472 Acetylation 1551 K EP300; P300 Q09472 Acetylation 1554 K EP300; P300 Q09472 Acetylation 1555 K EP300; P300 Q09472 Acetylation 1558 K EP300; P300 Q09472 Acetylation 1560 K EP300; P300 Q09472 Acetylation 1570 K EP300; P300 Q09472 Acetylation 1583 K EP300; P300 Q09472 Acetylation 1590 K EP300; P300 Q09472 Acetylation 1637 K EP300; P300 Q09472 Acetylation 1674 K EP300; P300 Q09472 Acetylation 1900 K EP300; P300 Q09472 Acetylation 1167 K EP300; P300 Q09472 Acetylation 14 K EP300; P300 Q09472 Acetylation 1001 K EP300; P300 Q09472 Acetylation 1340 K EP300; P300 Q09472 Acetylation 1707 K EP300; P300 Q09472 Acetylation 1760 K EP300; P300 Q09472 Acetylation 1762 K EP300; P300 Q09472 Acetylation 1800 K EP300; P300 Q09472 Acetylation 1794 K EP300; P300 Q09472 Butyrylation 291 K EP300; P300 Q09472 Butyrylation 1546 K EP300; P300 Q09472 Butyrylation 1549 K EP300; P300 Q09472 Butyrylation 1550 K EP300; P300 Q09472 Butyrylation 1551 K EP300; P300 Q09472 Butyrylation 1554 K EP300; P300 Q09472 Butyrylation 1555 K EP300; P300 Q09472 Butyrylation 1558 K EP300; P300 Q09472 Butyrylation 1560 K EP300; P300 Q09472 Butyrylation 1568 K EP300; P300 Q09472 Butyrylation 1769 K EP300; P300 Q09472 Propionylation 79 K EP300; P300 Q09472 Propionylation 291 K EP300; P300 Q09472 Propionylation 373 K EP300; P300 Q09472 Propionylation 601 K EP300; P300 Q09472 Propionylation 614 K EP300; P300 Q09472 Propionylation 1045 K EP300; P300 Q09472 Propionylation 1046 K EP300; P300 Q09472 Propionylation 1542 K EP300; P300 Q09472 Propionylation 1546 K EP300; P300 Q09472 Propionylation 1549 K EP300; P300 Q09472 Propionylation 1550 K EP300; P300 Q09472 Propionylation 1551 K EP300; P300 Q09472 Propionylation 1554 K EP300; P300 Q09472 Propionylation 1555 K EP300; P300 Q09472 Propionylation 1558 K EP300; P300 Q09472 Propionylation 1560 K EP300; P300 Q09472 Propionylation 1568 K EP300; P300 Q09472 Propionylation 1569 K EP300; P300 Q09472 Propionylation 1707 K EP300; P300 Q09472 Propionylation 1769 K EP300; P300 Q09472 Propionylation 1772 K EP300; P300 Q09472 Sumoylation 1020 K EP300; P300 Q09472 Sumoylation 1024 K EP300; P300 Q09472 Ubiquitination 1637 K EP300; P300 Q09472 Ubiquitination 1499 K EP300; P300 Q09472 Ubiquitination 614 K

PTM - dbPAF Gene Name UniProt ID Position Type Species EP300; P300 Q09472 1032 T Homo sapiens(Human) EP300; P300 Q09472 1037 S Homo sapiens(Human) EP300; P300 Q09472 1038 S Homo sapiens(Human) EP300; P300 Q09472 1044 S Homo sapiens(Human) EP300; P300 Q09472 106 S Homo sapiens(Human) EP300; P300 Q09472 1135 T Homo sapiens(Human) EP300; P300 Q09472 12 S Homo sapiens(Human) EP300; P300 Q09472 1295 S Homo sapiens(Human) EP300; P300 Q09472 1296 T Homo sapiens(Human) EP300; P300 Q09472 1355 Y Homo sapiens(Human) EP300; P300 Q09472 1414 Y Homo sapiens(Human) EP300; P300 Q09472 1421 Y Homo sapiens(Human) EP300; P300 Q09472 1424 Y Homo sapiens(Human) EP300; P300 Q09472 1446 Y Homo sapiens(Human) EP300; P300 Q09472 1533 T Homo sapiens(Human) EP300; P300 Q09472 1534 S Homo sapiens(Human) EP300; P300 Q09472 1577 S Homo sapiens(Human) EP300; P300 Q09472 1581 S Homo sapiens(Human) EP300; P300 Q09472 1585 Y Homo sapiens(Human) EP300; P300 Q09472 1716 S Homo sapiens(Human) EP300; P300 Q09472 1724 T Homo sapiens(Human) EP300; P300 Q09472 1726 S Homo sapiens(Human) EP300; P300 Q09472 1734 S Homo sapiens(Human) EP300; P300 Q09472 1754 S Homo sapiens(Human) EP300; P300 Q09472 1834 S Homo sapiens(Human) EP300; P300 Q09472 1857 T Homo sapiens(Human) EP300; P300 Q09472 1859 T Homo sapiens(Human) EP300; P300 Q09472 19 S Homo sapiens(Human) EP300; P300 Q09472 1960 T Homo sapiens(Human) EP300; P300 Q09472 2039 S Homo sapiens(Human) EP300; P300 Q09472 2219 Y Homo sapiens(Human) EP300; P300 Q09472 2279 S Homo sapiens(Human) EP300; P300 Q09472 2309 S Homo sapiens(Human) EP300; P300 Q09472 2315 S Homo sapiens(Human) EP300; P300 Q09472 2320 S Homo sapiens(Human) EP300; P300 Q09472 2325 S Homo sapiens(Human) EP300; P300 Q09472 2326 S Homo sapiens(Human) EP300; P300 Q09472 2328 S Homo sapiens(Human) EP300; P300 Q09472 2366 S Homo sapiens(Human) EP300; P300 Q09472 24 S Homo sapiens(Human) EP300; P300 Q09472 255 S Homo sapiens(Human) EP300; P300 Q09472 285 S Homo sapiens(Human) EP300; P300 Q09472 317 T Homo sapiens(Human) EP300; P300 Q09472 499 S Homo sapiens(Human) EP300; P300 Q09472 611 Y Homo sapiens(Human) EP300; P300 Q09472 620 Y Homo sapiens(Human) EP300; P300 Q09472 629 Y Homo sapiens(Human) EP300; P300 Q09472 630 Y Homo sapiens(Human) EP300; P300 Q09472 638 Y Homo sapiens(Human) EP300; P300 Q09472 831 S Homo sapiens(Human) EP300; P300 Q09472 833 S Homo sapiens(Human) EP300; P300 Q09472 839 T Homo sapiens(Human) EP300; P300 Q09472 841 T Homo sapiens(Human) EP300; P300 Q09472 845 T Homo sapiens(Human) EP300; P300 Q09472 885 T Homo sapiens(Human) EP300; P300 Q09472 887 T Homo sapiens(Human) EP300; P300 Q09472 89 S Homo sapiens(Human) EP300; P300 Q09472 890 T Homo sapiens(Human) EP300; P300 Q09472 891 T Homo sapiens(Human) EP300; P300 Q09472 938 T Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q09472 K14-ac Acetylation EPGPPsAkRPKLsSP Q09472 K77-ac Acetylation MVQDAASkHkQLSEL Q09472 K79-ac Acetylation QDAASkHkQLSELLR Q09472 K291-ac Acetylation LsPFAMDkkAVPGGG Q09472 K292-ac Acetylation sPFAMDkkAVPGGGM Q09472 K336-ac Acetylation TADPEKRkLIQQQLV Q09472 K350-ac Acetylation VLLLHAHkCQRREQA Q09472 K373-ac Acetylation LPHCRTMkNVLNHMT Q09472 K386-ac Acetylation MTHCQSGkSCQVAHC Q09472 K404-ac Acetylation RQIISHWkNCTRHDC Q09472 K418-ac Acetylation CPVCLPLkNAGDkRN Q09472 K423-ac Acetylation PLkNAGDkRNQQPIL Q09472 K489-ac Acetylation TQPQVQAkNQQNQQP Q09472 K569-ac Acetylation PSTTGIRkQWHEDIT Q09472 K601-ac Acetylation TPDPAALkDRRMENL Q09472 K614-ac Acetylation NLVAyARkVEGDMyE Q09472 K636-ac Acetylation yyHLLAEkIYKIQKE Q09472 K970-ac Acetylation NSQAIAEkQPSQEVk Q09472 K977-ac Acetylation kQPSQEVkMEAkMEV Q09472 K981-ac Acetylation QEVkMEAkMEVDQPE Q09472 K1001-ac Acetylation PEDISESkVEDCkME Q09472 K1006-ac Acetylation ESkVEDCkMESTETE Q09472 K1020-ac Acetylation EERSTELkTEIkEEE Q09472 K1024-ac Acetylation TELkTEIkEEEDQPS Q09472 K1045-ac Acetylation sPAPGQskkkIFKPE Q09472 K1046-ac Acetylation PAPGQskkkIFKPEE Q09472 K1047-ac Acetylation APGQskkkIFKPEEL Q09472 K1094-ac Acetylation PDyFDIVkSPMDLST Q09472 K1103-ac Acetylation PMDLSTIkRkLDTGQ Q09472 K1105-ac Acetylation DLSTIkRkLDTGQYQ Q09472 K1144-ac Acetylation RVYKYCSkLSEVFEQ Q09472 K1167-ac Acetylation LGYCCGRkLEFSPQT Q09472 K1180-ac Acetylation QTLCCYGkQLCTIPR Q09472 K1203-ac Acetylation NRYHFCEkCFNEIQG Q09472 K1228-ac Acetylation QPQTTINkEQFSKRK Q09472 K1331-ac Acetylation RVVHASDkTVEVkPG Q09472 K1336-ac Acetylation SDkTVEVkPGMkARF Q09472 K1340-ac Acetylation VEVkPGMkARFVDSG Q09472 K1427-ac Acetylation GYLEYVKkLGYTTGH Q09472 K1473-ac Acetylation WYKKMLDkAVSERIV Q09472 K1499-ac Acetylation EDRLTSAkELPYFEG Q09472 K1518-ac Acetylation NVLEESIkELEQEEE Q09472 K1528-ac Acetylation EQEEEERkREENtsN Q09472 K1542-ac Acetylation NESTDVTkGDSkNAk Q09472 K1546-ac Acetylation DVTkGDSkNAkkkNN Q09472 K1549-ac Acetylation kGDSkNAkkkNNkkT Q09472 K1550-ac Acetylation GDSkNAkkkNNkkTS Q09472 K1551-ac Acetylation DSkNAkkkNNkkTSk Q09472 K1554-ac Acetylation NAkkkNNkkTSkNkS Q09472 K1555-ac Acetylation AkkkNNkkTSkNkSS Q09472 K1558-ac Acetylation kNNkkTSkNkSSLSR Q09472 K1560-ac Acetylation NkkTSkNkSSLSRGN Q09472 K1568-ac Acetylation SSLSRGNkkkPGMPN Q09472 K1569-ac Acetylation SLSRGNkkkPGMPNV Q09472 K1570-ac Acetylation LSRGNkkkPGMPNVs Q09472 K1583-ac Acetylation VsNDLsQkLYATMEk Q09472 K1590-ac Acetylation kLYATMEkHKEVFFV Q09472 K1637-ac Acetylation FLTLARDkHLEFSSL Q09472 K1674-ac Acetylation VYTCNECkHHVETRW Q09472 K1699-ac Acetylation CITCYNTkNHDHkME Q09472 K1704-ac Acetylation NTkNHDHkMEkLGLG Q09472 K1707-ac Acetylation NHDHkMEkLGLGLDD Q09472 K1760-ac Acetylation CsLPSCQkMkRVVQH Q09472 K1762-ac Acetylation LPSCQkMkRVVQHTk Q09472 K1769-ac Acetylation kRVVQHTkGCkRkTN Q09472 K1772-ac Acetylation VQHTkGCkRkTNGGC Q09472 K1774-ac Acetylation HTkGCkRkTNGGCPI Q09472 K1783-ac Acetylation NGGCPICkQLIALCC Q09472 K1794-ac Acetylation ALCCYHAkHCQENkC Q09472 K1800-ac Acetylation AkHCQENkCPVPFCL Q09472 K1810-ac Acetylation VPFCLNIkQkLRQQQ Q09472 K1812-ac Acetylation FCLNIkQkLRQQQLQ Q09472 K1900-ac Acetylation AGPVSQGkAAGQVtP Q09472 K2086-ac Acetylation QLLAAFIkQRAAkYA Q09472 K2091-ac Acetylation FIkQRAAkYANSNPQ Q09472 R237-m1 Methylation MGGQTGLrGPQPLkM Q09472 K243-m1 Methylation LrGPQPLkMGMMNNP Q09472 R705-m1 Methylation VPNQMMPrITPQSGL Q09472 R728-m1 Methylation AQPPIVPrQTPPLQH Q09472 R2059-m2 Methylation QNLLRTLrSPSSPLQ Q09472 R2059-m1 Methylation QNLLRTLrSPSSPLQ Q09472 R2142-me Methylation PMQAGVQrAGLPQQQ Q09472 R2226-m1 Methylation yPPQQQQrMQHHMQQ Q09472 R2317-m1 Methylation PQPVPsPrPQsQPPH Q09472 R2330-m1 Methylation PHssPsPrMQPQPSP Q09472 S12-p Phosphorylation VVEPGPPsAkRPKLs Q09472 S19-p Phosphorylation sAkRPKLsSPALSAS Q09472 S89-p Phosphorylation SELLRSGsSPNLNMG Q09472 S106-p Phosphorylation GPGQVMAsQAQQSSP Q09472 S285-p Phosphorylation TVLSNNLsPFAMDkk Q09472 T317-p Phosphorylation VQQPGLVtPVAQGMG Q09472 S499-p Phosphorylation QNQQPGQsPQGMRPM Q09472 Y611-p Phosphorylation RMENLVAyARkVEGD Q09472 Y620-p Phosphorylation RkVEGDMyESANNRA Q09472 Y629-p Phosphorylation SANNRAEyyHLLAEk Q09472 Y630-p Phosphorylation ANNRAEyyHLLAEkI Q09472 S831-p Phosphorylation QPALHQNsPsPVPSR Q09472 S833-p Phosphorylation ALHQNsPsPVPSRtP Q09472 T839-p Phosphorylation PsPVPSRtPtPHHtP Q09472 T841-p Phosphorylation PVPSRtPtPHHtPPS Q09472 T845-p Phosphorylation RtPtPHHtPPSIGAQ Q09472 T885-p Phosphorylation LHPPPRQtPtPPTtQ Q09472 T887-p Phosphorylation PPPRQtPtPPTtQLP Q09472 T891-p Phosphorylation QtPtPPTtQLPQQVQ Q09472 T938-p Phosphorylation LLPPQPAtPLSQPAV Q09472 S1037-p Phosphorylation PSTSATQssPAPGQs Q09472 S1038-p Phosphorylation STSATQssPAPGQsk Q09472 S1044-p Phosphorylation ssPAPGQskkkIFKP Q09472 Y1089-p Phosphorylation QLLGIPDyFDIVkSP Q09472 T1135-p Phosphorylation AWLYNRKtSRVYKYC Q09472 S1295-p Phosphorylation FSAKRLPstRLGTFL Q09472 T1296-p Phosphorylation SAKRLPstRLGTFLE Q09472 Y1355-p Phosphorylation EMAESFPyRTKALFA Q09472 Y1446-p Phosphorylation PPSEGDDyIFHCHPP Q09472 T1533-p Phosphorylation ERkREENtsNESTDV Q09472 S1534-p Phosphorylation RkREENtsNESTDVT Q09472 S1577-p Phosphorylation kPGMPNVsNDLsQkL Q09472 S1581-p Phosphorylation PNVsNDLsQkLYATM Q09472 S1726-p Phosphorylation QQAAATQsPGDSRRL Q09472 S1754-p Phosphorylation QCRNANCsLPSCQkM Q09472 S1834-p Phosphorylation MLRRRMAsMQRTGVV Q09472 T1857-p Phosphorylation PTPATPTtPtGQQPT Q09472 T1859-p Phosphorylation PATPTtPtGQQPTTP Q09472 T1906-p Phosphorylation GkAAGQVtPPtPPQT Q09472 T1909-p Phosphorylation AGQVtPPtPPQTAQP Q09472 T1960-p Phosphorylation QHQMPPMtPMAPMGM Q09472 S2039-p Phosphorylation GLGQVGIsPLKPGTV Q09472 Y2219-p Phosphorylation QQPQGVGyPPQQQQr Q09472 S2279-p Phosphorylation PVQPNPMsPQQHMLP Q09472 S2309-p Phosphorylation SLSNQVRsPQPVPsP Q09472 S2315-p Phosphorylation RsPQPVPsPrPQsQP Q09472 S2320-p Phosphorylation VPsPrPQsQPPHssP Q09472 S2325-p Phosphorylation PQsQPPHssPsPrMQ Q09472 S2326-p Phosphorylation QsQPPHssPsPrMQP Q09472 S2328-p Phosphorylation QPPHssPsPrMQPQP Q09472 S2366-p Phosphorylation MEQGHFAsPDQNSML Q09472 K1020-sm Sumoylation EERSTELkTEIkEEE Q09472 K1024-sm Sumoylation TELkTEIkEEEDQPS Q09472 K614-ub Ubiquitination NLVAyARkVEGDMyE Q09472 K1583-ub Ubiquitination VsNDLsQkLYATMEk Q09472 K1590-ub Ubiquitination kLYATMEkHKEVFFV Q09472 K1637-ub Ubiquitination FLTLARDkHLEFSSL

PTM - dbPTM UniProt ID Position Code Type Resources References Q09472 2 A Acetylation Swiss-Prot 1010711 19413330 Q09472 89 S Phosphorylation Swiss-Prot 1010711 11518699 Q09472 285 S Phosphorylation Swiss-Prot 1010711 19413330 Q09472 580 R Methylation Swiss-Prot 1010711 11701890 Q09472 604 R Methylation Swiss-Prot 1010711 11701890 Q09472 636 K Acetylation Swiss-Prot 1010711 19608861 Q09472 885 T Phosphorylation Swiss-Prot 1010711 19413330 Q09472 887 T Phosphorylation Swiss-Prot 1010711 19413330 Q09472 977 K Acetylation Swiss-Prot 1010711 19608861 Q09472 981 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1020 K Sumoylation Swiss-Prot 1010711 12718889 Q09472 1020 K Acetylation Swiss-Prot 1010711 15632193 Q09472 1024 K Sumoylation Swiss-Prot 1010711 12718889 Q09472 1024 K Acetylation Swiss-Prot 1010711 15632193 Q09472 1038 S Phosphorylation Swiss-Prot 1010711 19413330 Q09472 1103 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1336 K Acetylation Swiss-Prot 1010711 17065153 Q09472 1473 K Acetylation Swiss-Prot 1010711 17065153 Q09472 1499 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1542 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1546 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1549 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1554 K Acetylation Swiss-Prot 1010711 16916647;19608861 Q09472 1555 K Acetylation Swiss-Prot 1010711 16916647;19608861 Q09472 1558 K Acetylation Swiss-Prot 1010711 16916647;19608861 Q09472 1560 K Acetylation Swiss-Prot 1010711 16916647;19608861 Q09472 1583 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1590 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1674 K Acetylation Swiss-Prot 1010711 19608861 Q09472 1734 S Phosphorylation Swiss-Prot 1010711 19369195 Q09472 1857 T Phosphorylation Swiss-Prot 1010711 19413330 Q09472 1859 T Phosphorylation Swiss-Prot 1010711 19413330 Q09472 2142 R Methylation Swiss-Prot 1010711 15731352 Q09472 1550 K Acetylation Swiss-Prot 1010711 - Q09472 1551 K Acetylation Swiss-Prot 1010711 - Q09472 1568 K Acetylation Swiss-Prot 1010711 - Q09472 1569 K Acetylation Swiss-Prot 1010711 - Q09472 1637 K Acetylation Swiss-Prot 1010711 - Q09472 2142 R Citrullination Swiss-Prot 1010711 - Q09472 1037 S Phosphorylation PhosphoELM.10011 18669648 Q09472 89 S Phosphorylation PhosphoELM.10011 15006641;12590608;11020388;12590608;12590608;12590608;12379484 Q09472 24 S Phosphorylation PhosphoELM.10011 12590608 Q09472 1834 S Phosphorylation PhosphoELM.10011 11116148 Q09472 885 T Phosphorylation PhosphoELM.10011 18669648 Q09472 2142 R Methylation Phosphositeplus.1010730 15731352 Q09472 1020 K Sumoylation Phosphositeplus.1010730 12718889 Q09472 1024 K Sumoylation Phosphositeplus.1010730 12718889 Q09472 1637 K Ubiquitylation Phosphositeplus.1010730 21890473 Q09472 1001 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1020 K Acetylation Phosphositeplus.1010730 15632193;18995842 Q09472 1024 K Acetylation Phosphositeplus.1010730 15632193 Q09472 1045 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1046 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1047 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1094 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1103 K Acetylation Phosphositeplus.1010730 19608861 Q09472 1105 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1144 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1167 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1180 K Acetylation Phosphositeplus.1010730 18995842;19608861 Q09472 1203 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1228 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1331 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1336 K Acetylation Phosphositeplus.1010730 15004546;15887180;18995842 Q09472 1340 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1427 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1473 K Acetylation Phosphositeplus.1010730 15004546;15887180 Q09472 1499 K Acetylation Phosphositeplus.1010730 15004546;15887180;18995842;19608861 Q09472 1518 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1528 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1542 K Acetylation Phosphositeplus.1010730 15004546;15887180;17065153;18995842;19608861;20167786 Q09472 1546 K Acetylation Phosphositeplus.1010730 15004546;15887180;17065153;18995842;19608861;20167786 Q09472 1549 K Acetylation Phosphositeplus.1010730 15004546;15887180;17065153;18995842;19608861;20167786 Q09472 1550 K Acetylation Phosphositeplus.1010730 15004546;15887180;17065153;18995842 Q09472 1551 K Acetylation Phosphositeplus.1010730 15004546;15887180;17065153;18995842 Q09472 1554 K Acetylation Phosphositeplus.1010730 15004546;15887180;16916647;17065153;18995842;19608861 Q09472 1555 K Acetylation Phosphositeplus.1010730 15004546;15887180;16916647;17065153;18995842;19608861 Q09472 1558 K Acetylation Phosphositeplus.1010730 15004546;15887180;16916647;17065153;18995842;19608861;20167786 Q09472 1560 K Acetylation Phosphositeplus.1010730 15004546;15887180;16916647;17065153;18995842;19608861 Q09472 1568 K Acetylation Phosphositeplus.1010730 17065153;18995842 Q09472 1569 K Acetylation Phosphositeplus.1010730 17065153;18995842 Q09472 1570 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1583 K Acetylation Phosphositeplus.1010730 18995842;19608861 Q09472 1590 K Acetylation Phosphositeplus.1010730 18995842;19608861 Q09472 1637 K Acetylation Phosphositeplus.1010730 15004546;15887180 Q09472 1674 K Acetylation Phosphositeplus.1010730 18995842;19608861 Q09472 1699 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1704 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1707 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1760 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1762 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1769 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1772 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1774 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1783 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1794 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1800 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1810 K Acetylation Phosphositeplus.1010730 18995842 Q09472 1812 K Acetylation Phosphositeplus.1010730 18995842 Q09472 2086 K Acetylation Phosphositeplus.1010730 18995842 Q09472 2091 K Acetylation Phosphositeplus.1010730 18995842 Q09472 291 K Acetylation Phosphositeplus.1010730 18995842 Q09472 292 K Acetylation Phosphositeplus.1010730 18995842 Q09472 336 K Acetylation Phosphositeplus.1010730 18995842 Q09472 350 K Acetylation Phosphositeplus.1010730 18995842 Q09472 373 K Acetylation Phosphositeplus.1010730 18995842 Q09472 386 K Acetylation Phosphositeplus.1010730 18995842 Q09472 404 K Acetylation Phosphositeplus.1010730 18995842 Q09472 418 K Acetylation Phosphositeplus.1010730 18995842 Q09472 423 K Acetylation Phosphositeplus.1010730 18995842 Q09472 489 K Acetylation Phosphositeplus.1010730 18995842 Q09472 569 K Acetylation Phosphositeplus.1010730 18995842 Q09472 601 K Acetylation Phosphositeplus.1010730 18995842 Q09472 614 K Acetylation Phosphositeplus.1010730 18995842 Q09472 636 K Acetylation Phosphositeplus.1010730 18995842;19608861 Q09472 77 K Acetylation Phosphositeplus.1010730 18995842 Q09472 79 K Acetylation Phosphositeplus.1010730 18995842 Q09472 970 K Acetylation Phosphositeplus.1010730 18995842 Q09472 977 K Acetylation Phosphositeplus.1010730 19608861 Q09472 981 K Acetylation Phosphositeplus.1010730 18995842;19608861 Q09472 1037 S Phosphorylation Phosphositeplus.1010730 19664995 Q09472 1038 S Phosphorylation Phosphositeplus.1010730 19664994;19664995;21406692 Q09472 106 S Phosphorylation Phosphositeplus.1010730 20471956;21108945 Q09472 12 S Phosphorylation Phosphositeplus.1010730 22465714 Q09472 1295 S Phosphorylation Phosphositeplus.1010730 20363803 Q09472 1834 S Phosphorylation Phosphositeplus.1010730 11116148;16024795;16926151;17623675 Q09472 2279 S Phosphorylation Phosphositeplus.1010730 17623675 Q09472 2309 S Phosphorylation Phosphositeplus.1010730 20363803 Q09472 2315 S Phosphorylation Phosphositeplus.1010730 17623675 Q09472 2328 S Phosphorylation Phosphositeplus.1010730 20363803 Q09472 2366 S Phosphorylation Phosphositeplus.1010730 17623675 Q09472 831 S Phosphorylation Phosphositeplus.1010730 18695000 Q09472 833 S Phosphorylation Phosphositeplus.1010730 18695000 Q09472 89 S Phosphorylation Phosphositeplus.1010730 11020388;11518699;12379484;15006641;21940946;22465714 Q09472 1296 T Phosphorylation Phosphositeplus.1010730 20363803 Q09472 1960 T Phosphorylation Phosphositeplus.1010730 17623675 Q09472 317 T Phosphorylation Phosphositeplus.1010730 17623675 Q09472 839 T Phosphorylation Phosphositeplus.1010730 18695000 Q09472 841 T Phosphorylation Phosphositeplus.1010730 18695000 Q09472 845 T Phosphorylation Phosphositeplus.1010730 18695000 Q09472 885 T Phosphorylation Phosphositeplus.1010730 18695000 Q09472 887 T Phosphorylation Phosphositeplus.1010730 18695000 Q09472 938 T Phosphorylation Phosphositeplus.1010730 17623675 Q09472 1414 Y Phosphorylation Phosphositeplus.1010730 18083107 Q09472 1421 Y Phosphorylation Phosphositeplus.1010730 18083107 Q09472 1424 Y Phosphorylation Phosphositeplus.1010730 18083107 Q09472 611 Y Phosphorylation Phosphositeplus.1010730 20736484 Q09472 620 Y Phosphorylation Phosphositeplus.1010730 20736484 Q09472 629 Y Phosphorylation Phosphositeplus.1010730 20736484 Q09472 630 Y Phosphorylation Phosphositeplus.1010730 20736484 Q09472 638 Y Phosphorylation Phosphositeplus.1010730 18083107 Q09472 291 K Acetylation HPRD 9.0 19608861 Q09472 636 K Acetylation HPRD 9.0 19608861 Q09472 977 K Acetylation HPRD 9.0 19608861 Q09472 981 K Acetylation HPRD 9.0 19608861 Q09472 1103 K Acetylation HPRD 9.0 19608861 Q09472 1528 K Acetylation HPRD 9.0 19608861 Q09472 1570 K Acetylation HPRD 9.0 19608861 Q09472 1583 K Acetylation HPRD 9.0 19608861 Q09472 1590 K Acetylation HPRD 9.0 19608861 Q09472 1674 K Acetylation HPRD 9.0 19608861 Q09472 1473 K Acetylation HPRD 9.0 15004546 Q09472 1499 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1542 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1546 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1549 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1550 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1551 K Acetylation HPRD 9.0 15004546 Q09472 1554 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1555 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1558 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1560 K Acetylation HPRD 9.0 15004546,19608861 Q09472 1637 K Acetylation HPRD 9.0 15004546 Q09472 1020 K Deacetylation HPRD 9.0 15632193 Q09472 1024 K Deacetylation HPRD 9.0 15632193 Q09472 285 S Phosphorylation HPRD 9.0 19413330 Q09472 1037 S Phosphorylation HPRD 9.0 18669648,19664995,18452278 Q09472 1038 S Phosphorylation HPRD 9.0 19413330,19664995,19664994,18452278 Q09472 885 T Phosphorylation HPRD 9.0 18669648 Q09472 887 T Phosphorylation HPRD 9.0 19413330 Q09472 1857 T Phosphorylation HPRD 9.0 19413330 Q09472 1859 T Phosphorylation HPRD 9.0 19413330 Q09472 1834 S Phosphorylation (AKT1) HPRD 9.0 11116148 Q09472 89 S Phosphorylation (PRKCD) HPRD 9.0 12379484,11020388 Q09472 1020 K Sumoylation HPRD 9.0 15632193 Q09472 1024 K Sumoylation HPRD 9.0 15632193 Q09472 580 R Methylation MeMo 2.0 11701890 Q09472 604 R Methylation MeMo 2.0 11701890 Q09472 1554 K Acetylation SysPTM 1.1 16916647 Q09472 1555 K Acetylation SysPTM 1.1 16916647 Q09472 1558 K Acetylation SysPTM 1.1 16916647 Q09472 1560 K Acetylation SysPTM 1.1 16916647

PTM - HPRD Symbol Position Code Type References EP300 1020 K Deacetylation 15632193 EP300 1020 K Sumoylation 15632193 EP300 1024 K Deacetylation 15632193 EP300 1024 K Sumoylation 15632193 EP300 1037 S Phosphorylation 18669648,19664995,18452278 EP300 1038 S Phosphorylation 19413330,19664995,19664994,18452278 EP300 1103 K Acetylation 19608861 EP300 1473 K Acetylation 15004546 EP300 1499 K Acetylation 15004546,19608861 EP300 1528 K Acetylation 19608861 EP300 1542 K Acetylation 15004546,19608861 EP300 1546 K Acetylation 15004546,19608861 EP300 1549 K Acetylation 15004546,19608861 EP300 1550 K Acetylation 15004546,19608861 EP300 1551 K Acetylation 15004546 EP300 1554 K Acetylation 15004546,19608861 EP300 1555 K Acetylation 15004546,19608861 EP300 1558 K Acetylation 15004546,19608861 EP300 1560 K Acetylation 15004546,19608861 EP300 1570 K Acetylation 19608861 EP300 1583 K Acetylation 19608861 EP300 1590 K Acetylation 19608861 EP300 1637 K Acetylation 15004546 EP300 1674 K Acetylation 19608861 EP300 1834 S Phosphorylation 11116148 EP300 1857 T Phosphorylation 19413330 EP300 1859 T Phosphorylation 19413330 EP300 285 S Phosphorylation 19413330 EP300 291 K Acetylation 19608861 EP300 636 K Acetylation 19608861 EP300 885 T Phosphorylation 18669648 EP300 887 T Phosphorylation 19413330 EP300 89 S Phosphorylation 12379484,11020388 EP300 977 K Acetylation 19608861 EP300 981 K Acetylation 19608861

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q09472 24 S 12590608 CaM-KIV LTP Phosphorylation Q09472 89 S 15006641 LTP Phosphorylation Q09472 89 S 12590608 AMPK_group LTP Phosphorylation Q09472 89 S 11020388 AMPK_group LTP Phosphorylation Q09472 89 S 12590608 CaM-KI_group LTP Phosphorylation Q09472 89 S 12590608 PKC_alpha LTP Phosphorylation Q09472 89 S 12590608 PKC_delta LTP Phosphorylation Q09472 89 S 12379484 PKC_delta LTP Phosphorylation Q09472 1834 S 11116148 PKB_group LTP Phosphorylation Q09472 1037 S 18669648 HTP Phosphorylation Q09472 885 T 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q09472 2 N-acetylalanine 19413330;22223895 Q09472 89 Phosphoserine; by AMPK 11518699;16574662 Q09472 418 N6-acetyllysine 18995842 Q09472 423 N6-acetyllysine 18995842 Q09472 580 Omega-N-methylated arginine; by CARM1 11701890 Q09472 604 Omega-N-methylated arginine; by CARM1 11701890 Q09472 636 N6-acetyllysine 19608861 Q09472 977 N6-acetyllysine 19608861 Q09472 1020 N6-acetyllysine; alternate 15632193 Q09472 1024 N6-acetyllysine; alternate 15632193 Q09472 1038 Phosphoserine 21406692;23186163;24275569 Q09472 1336 N6-acetyllysine 17065153 Q09472 1473 N6-acetyllysine 17065153 Q09472 1499 N6-acetyllysine; by autocatalysis 15004546 Q09472 1542 N6-acetyllysine 19608861;18995842 Q09472 1546 N6-acetyllysine 19608861;18995842 Q09472 1549 N6-acetyllysine; by autocatalysis 15004546;18995842 Q09472 1554 N6-acetyllysine; by autocatalysis 19608861;15004546 Q09472 1555 N6-acetyllysine 19608861 Q09472 1558 N6-acetyllysine 19608861;15004546 Q09472 1560 N6-acetyllysine; by autocatalysis 19608861;15004546 Q09472 1583 N6-acetyllysine 19608861 Q09472 1699 N6-acetyllysine 18995842 Q09472 1704 N6-acetyllysine 18995842 Q09472 1707 N6-acetyllysine 18995842 Q09472 1726 Phosphoserine 23186163 Q09472 2142 Citrulline; by PADI4; alternate 15731352

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type EP300 IPI00020985 K 1103 MDLSTIaKRKLDTG acetylation EP300 IPI00020985 K 1180 TLCCYGaKQLCTIP acetylation EP300 IPI00020985 K 1499 DRLTSAaKELPYFE acetylation EP300 IPI00020985 K 1542 ESTDVTaKGDSKNA acetylation EP300 IPI00020985 K 1546 VTKGDSaKNAKKKN acetylation EP300 IPI00020985 K 1549 GDSKNAaKKKNNKK acetylation EP300 IPI00020985 K 1550 DSKNAKaKKNNKKT acetylation EP300 IPI00020985 K 1554 AKKKNNaKKTSKNK acetylation EP300 IPI00020985 K 1555 KKKNNKaKTSKNKS acetylation EP300 IPI00020985 K 1558 NNKKTSaKNKSSLS acetylation EP300 IPI00020985 K 1560 KKTSKNaKSSLSRG acetylation EP300 IPI00020985 K 1583 SNDLSQaKLYATME acetylation EP300 IPI00020985 K 1590 LYATMEaKHKEVFF acetylation EP300 IPI00020985 K 1674 YTCNECaKHHVETR acetylation EP300 IPI00020985 K 291 SPFAMDaKKAVPGG acetylation EP300 IPI00020985 K 636 YHLLAEaKIYKIQK acetylation EP300 IPI00020985 K 977 QPSQEVaKMEAKME acetylation EP300 IPI00020985 K 981 EVKMEAaKMEVDQP acetylation EP300 IPI00020985 S 1734 GDSRRLpSIQRCIQ phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID EP300 Homo sapiens (Human) 1637 "1637,LTLARDKHLEFSS" 1637:21890473 EP300 Homo sapiens (Human) 1637 "1637,LTLARDKHLEFSS" 1637:21890473