PTM - CPLM Gene Name UniProt ID Type Position Code MID1; FXY; RNF59; TRIM18; XPRF O15344 Ubiquitination 232 K

PTM - dbPAF Gene Name UniProt ID Position Type Species MID1; FXY; RNF59; TRIM18; XPRF O15344 213 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 311 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 378 Y Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 500 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 511 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 512 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 513 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 518 T Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 528 Y Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 572 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 590 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 64 T Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 66 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 78 T Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 90 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 92 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 96 S Homo sapiens(Human) MID1; FXY; RNF59; TRIM18; XPRF O15344 98 S Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type MID1; FXY; RNF59; TRIM18; XPRF rs35353746 AGC->GGC S->G 98 S VSGPNSPSETRRERA 98 Phosphorylation TypeI- MID1; FXY; RNF59; TRIM18; XPRF rs35353746 AGC->GGC S->G 98 S VSGPNSPSETRRERA 98 Phosphorylation TypeI- MID1; FXY; RNF59; TRIM18; XPRF rs35353746 AGC->GGC S->G 98 S VSGPNSPSETRRERA 98 Phosphorylation TypeI- MID1; FXY; RNF59; TRIM18; XPRF rs35353746 AGC->GGC S->G 92 S RFQKASVSGPNSPSE 92 Phosphorylation TypeIII- MID1; FXY; RNF59; TRIM18; XPRF rs35353746 AGC->GGC S->G 92 S RFQKASVSGPNSPSE 92 Phosphorylation TypeIII- MID1; FXY; RNF59; TRIM18; XPRF rs35716955 CCT->CTT P->L 92 S RFQKASVSGPNSPSE 92 Phosphorylation TypeIII- MID1; FXY; RNF59; TRIM18; XPRF rs35353746 AGC->GGC S->G 92 S RFQKASVSGPNSPSE 92 Phosphorylation TypeIII- MID1; FXY; RNF59; TRIM18; XPRF rs35716955 CCT->CTT P->L 92 S RFQKASVSGPNSPSE 92 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O15344 R68-m1 Methylation HVITLSQrGLDGLKR O15344 T78-p Phosphorylation DGLKRNVtLQNIIDR O15344 S90-p Phosphorylation IDRFQKAsVsGPNsP O15344 S92-p Phosphorylation RFQKAsVsGPNsPsE O15344 S96-p Phosphorylation AsVsGPNsPsETRRE O15344 S98-p Phosphorylation VsGPNsPsETRRERA O15344 T110-p Phosphorylation ERAFDANtMTSAEKV O15344 S213-p Phosphorylation DHQVAALsERYDKLK O15344 S311-p Phosphorylation QCIERSAsLISQAEH O15344 Y378-p Phosphorylation KLLECLDyLTAPNPP O15344 S500-p Phosphorylation AHRKLKVsHDNLtVE O15344 T505-p Phosphorylation KVsHDNLtVERDEsS O15344 S511-p Phosphorylation LtVERDEsSsKKSHt O15344 S513-p Phosphorylation VERDEsSsKKSHtPE O15344 T518-p Phosphorylation sSsKKSHtPERFTSQ O15344 Y528-p Phosphorylation RFTSQGSyGVAGNVF O15344 S572-p Phosphorylation HEWIGKNsASWALCR O15344 K232-ub Ubiquitination SNLTNLIkRNTELET

PTM - dbPTM UniProt ID Position Code Type Resources References O15344 90 S Phosphorylation Swiss-Prot 1010711 19413330 O15344 92 S Phosphorylation Swiss-Prot 1010711 17081983;19413330 O15344 96 S Phosphorylation Swiss-Prot 1010711 19413330 O15344 98 S Phosphorylation Swiss-Prot 1010711 17081983;19413330 O15344 92 S Phosphorylation PhosphoELM.10011 18669648;17081983 O15344 96 S Phosphorylation PhosphoELM.10011 18669648 O15344 98 S Phosphorylation PhosphoELM.10011 17081983 O15344 232 K Ubiquitylation Phosphositeplus.1010730 21890473 O15344 572 S Phosphorylation Phosphositeplus.1010730 20363803 O15344 92 S Phosphorylation Phosphositeplus.1010730 18669648;20363803;21406692 O15344 96 S Phosphorylation Phosphositeplus.1010730 18669648;19664995;20363803 O15344 98 S Phosphorylation Phosphositeplus.1010730 20068231 O15344 96 S Dephosphorylation HPRD 9.0 11371618 O15344 90 S Phosphorylation HPRD 9.0 20068231 O15344 92 S Phosphorylation HPRD 9.0 17081983,18669648,19413330,19651622,20068231 O15344 96 S Phosphorylation HPRD 9.0 11371618,18669648,19413330,19664995,20068231 O15344 96 S Phosphorylation HPRD 9.0 18669648,19413330,19664995,20068231 O15344 98 S Phosphorylation HPRD 9.0 17081983,19413330,19651622,20068231 O15344 92 S Phosphorylation SysPTM 1.1 17081983 O15344 98 S Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References MID1 90 S Phosphorylation 20068231 MID1 92 S Phosphorylation 17081983,18669648,19413330,19651622,20068231 MID1 96 S Dephosphorylation 11371618 MID1 96 S Phosphorylation 11371618,18669648,19413330,19664995,20068231 MID1 96 S Phosphorylation 18669648,19413330,19664995,20068231 MID1 98 S Phosphorylation 17081983,19413330,19651622,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O15344 96 S 18669648 HTP Phosphorylation O15344 92 S 18669648 HTP Phosphorylation O15344 92 S 17081983 HTP Phosphorylation O15344 98 S 17081983 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O15344 92 Phosphoserine 21406692;23186163 O15344 96 Phosphoserine 23186163 O15344 511 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type MID1 IPI00029324 S 92 FQKASVpSGPNSPS phosphorylation MID1 IPI00029324 S 98 SGPNSPpSETRRER phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 4281 110427 - K Ubiquitination 21890473 4281 110427 - K Ubiquitination 21143188

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID MID1 Homo sapiens (Human) 182 "182,NLTNLIKRNTELE" 182:21890473 MID1 Homo sapiens (Human) 232 "232,NLTNLIKRNTELE" 232:21890473 MID1 Homo sapiens (Human) 182 "182,NLTNLIKRNTELE" 182:21890473 MID1 Homo sapiens (Human) 232 "232,NLTNLIKRNTELE" 232:21890473 MID1 Homo sapiens (Human) 232 "232,NLTNLIKRNTELE" 232:21890473 MID1 Homo sapiens (Human) 232 "232,NLTNLIKRNTELE" 232:21890473