PTM - CPLM Gene Name UniProt ID Type Position Code MGRN1; KIAA0544; RNF156 O60291 Acetylation 259 K MGRN1; KIAA0544; RNF156 O60291 Ubiquitination 82 K MGRN1; KIAA0544; RNF156 O60291 Ubiquitination 164 K MGRN1; KIAA0544; RNF156 O60291 Ubiquitination 265 K MGRN1; KIAA0544; RNF156 O60291 Ubiquitination 101 K

PTM - dbPAF Gene Name UniProt ID Position Type Species MGRN1; KIAA0544; RNF156 O60291 100 Y Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 108 T Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 153 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 155 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 254 Y Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 337 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 342 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 361 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 367 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 402 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 407 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 411 Y Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 415 T Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 416 Y Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 417 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 453 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 454 T Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 457 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 459 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 460 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 490 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 492 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 506 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 515 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 523 S Homo sapiens(Human) MGRN1; KIAA0544; RNF156 O60291 524 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O60291 K101-ac Acetylation SLRLVRykDDADSPt O60291 K259-ac Acetylation EIyGIENkNNQETkP O60291 Y100-p Phosphorylation DSLRLVRykDDADSP O60291 T108-p Phosphorylation kDDADSPtEDGDKPR O60291 S153-p Phosphorylation RAVYSPKsPsLQSET O60291 S155-p Phosphorylation VYSPKsPsLQSETVH O60291 Y254-p Phosphorylation SYLLQEIyGIENkNN O60291 S337-p Phosphorylation RKKPGALsPVSFSPV O60291 S361-p Phosphorylation HSCPFKKsKPHPASL O60291 S402-p Phosphorylation LNGLRAVsPAIPsAP O60291 S407-p Phosphorylation AVsPAIPsAPLyEEI O60291 Y411-p Phosphorylation AIPsAPLyEEItysG O60291 T415-p Phosphorylation APLyEEItysGISDG O60291 Y416-p Phosphorylation PLyEEItysGISDGL O60291 S417-p Phosphorylation LyEEItysGISDGLS O60291 S457-p Phosphorylation APDSTLRsPssPIHE O60291 S459-p Phosphorylation DSTLRsPssPIHEED O60291 S460-p Phosphorylation STLRsPssPIHEEDE O60291 S490-p Phosphorylation AELALREsSsPESFI O60291 S492-p Phosphorylation LALREsSsPESFITE O60291 S506-p Phosphorylation EEVDESSsPQQGTRA O60291 S515-p Phosphorylation QQGTRAAsIENVLQD O60291 S523-p Phosphorylation IENVLQDssPEHCGR O60291 S524-p Phosphorylation ENVLQDssPEHCGRG O60291 K82-ub Ubiquitination PAPHEPVkTLRSLVN O60291 K101-ub Ubiquitination SLRLVRykDDADSPt O60291 K164-ub Ubiquitination QSETVHYkRGVSQQF O60291 K265-ub Ubiquitination NkNNQETkPSDDENS

PTM - dbPTM UniProt ID Position Code Type Resources References O60291 2 G Myristoylation Swiss-Prot 1010711 20213681 O60291 524 S Phosphorylation Swiss-Prot 1010711 18669648 O60291 459 S Phosphorylation PhosphoELM.10011 18669648 O60291 524 S Phosphorylation PhosphoELM.10011 18669648 O60291 454 T Phosphorylation PhosphoELM.10011 18669648 O60291 459 S Phosphorylation HPRD 9.0 18669648 O60291 524 S Phosphorylation HPRD 9.0 18669648,20068231 O60291 454 T Phosphorylation HPRD 9.0 18669648 O60291 524 S Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References MGRN1 454 T Phosphorylation 18669648 MGRN1 459 S Phosphorylation 18669648 MGRN1 524 S Phosphorylation 18669648,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O60291 524 S 18669648 HTP Phosphorylation O60291 454 T 18669648 HTP Phosphorylation O60291 459 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O60291 524 Phosphoserine 18669648;23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type MGRN1 IPI00297251 S 524 NVLQDSpSPEHCGR phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 23295 116890 - K Ubiquitination 21987572 23295 116890 - K Ubiquitination 21139048 23295 116890 - K Ubiquitination 21890473 23295 116890 - K Ubiquitination 21906983 23295 116890 - K FAT10ylation 22797925 23295 116890 - K Ubiquitination 21963094 23295 116890 - K Ubiquitination 22053931 23295 116890 - K Ubiquitination 23000965 23295 116890 - K Ubiquitination 25147182

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID MGRN1 Homo sapiens (Human) 82; 164 "82,APHEPVKTLRSLV; 164,SETVHYKRGVSQQ" 82:21890473; 164:21890473 MGRN1 Homo sapiens (Human) 101; 82; 164 "101,LRLVRYKDDADSP; 82,APHEPVKTLRSLV; 164,SETVHYKRGVSQQ" "101:21906983; 82:21890473; 164:21890473,21906983" MGRN1 Homo sapiens (Human) 101; 82; 164 "101,LRLVRYKDDADSP; 82,APHEPVKTLRSLV; 164,SETVHYKRGVSQQ" "101:21906983; 82:21890473; 164:21890473,21906983" MGRN1 Homo sapiens (Human) 101; 82; 164 "101,LRLVRYKDDADSP; 82,APHEPVKTLRSLV; 164,SETVHYKRGVSQQ" "101:21906983; 82:21890473; 164:21890473,21906983" MGRN1 Homo sapiens (Human) 101; 82; 164 "101,LRLVRYKDDADSP; 82,APHEPVKTLRSLV; 164,SETVHYKRGVSQQ" "101:21906983; 82:21890473; 164:21890473,21906983"