PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus APC PARD6A 20007894 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP LRCH3 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PRDX3 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G RPAP3 PARD6A 14676191 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G FBXO31 PARD6A 23469015 biogrid exp GP GP G P GP G GP GP G GP G GP GP G GP GP G GP G P GP GP GP GP GP GP GP G TUBG1 PARD6A 23469015 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G ORC2 PARD6A 26496610 biogrid,intact exp G G G G G GP G G GP G GP G GP GP G GP GP GP G P G GP G GP G GP GP G TP53BP2 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PRKCH PARD6A 17335965 hprd exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PIK3R4 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP G GP GP GP GP G PLXNA3 PARD6A 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G RICTOR PARD6A 20978191 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP GP GP GP G ARID5B PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP G GP GP G TTC3 PARD6A 26496610 biogrid,intact exp P P P P P DPP9 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G P GP GP GP GP GP GP GP G NKD1 PARD6A 19888210 i2d exp G G G G G P G G G G P GP SIRT6 PARD6A 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G GLS PARD6A 12629547 hprd exp G GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP G G GP G GP GP G GLUD1 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PIK3R3 PARD6A 25814554 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G P G GP G GP GP GP GP G SMARCA4 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G GRB2 PARD6A 25814554 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6A ZAK 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G P GP GP G GP G GP GP G PARD6A AXIN2 19888210 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G WDR92 PARD6A 14676191 biogrid,intact exp P P P P P P P P P P P P P P P P P P P P P P TMEM126A PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP G GP G GP GP GP GP G P GP GP GP GP GP GP GP G TCP10 PARD6A 10934474 hprd,intact exp G G GP P P GP G G P P G G DGKZ PARD6A 17350623 biogrid exp G G G G G GP G GP G G G G G GP G G GP G GP G G GP G G G GP GP G SMAD1 PARD6A 15761153 i2d exp G G G G G G G G GP G G G G G G G G G G G G G G G G G GP G NOL8 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G P GP GP G GP G GP GP PARD6A PIH1D1 14676191 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6A SUGT1 14676191 biogrid,intact exp G G G G G G G GP GP G GP G G G G GP G G GP G G G GP GP G GP GP G RASSF8 PARD6A 26496610 biogrid,intact exp GP GP G P GP G GP GP G GP P G P G GP GP G P G P GP P GP GP P GP GP G INADL PARD6A 17057644 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G DVL3 PARD6A 19888210 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G EPHB4 PARD6A 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP G GP G GP GP G PRKCG PARD6A 14676191 hprd,bci exp G G G G G GP G G G G G G G GP G G G G G G G KIF1B PARD6A 26496610 biogrid,intact exp G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G ELP3 PARD6A 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP G GP G GP GP G PARD6A PDRG1 14676191 biogrid,intact exp G GP G G G GP G GP GP G GP G GP G G GP GP GP GP G P G G GP GP G GP GP G PRKD1 PARD6A 25416956 intact exp GP GP G P GP G GP GP G GP P GP G G GP GP GP GP G P GP GP GP GP G GP GP G APP PARD6A 21244100 biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G P GP G G GP G G GP G ARHGAP17 PARD6A 16678097 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P G GP GP GP GP GP GP G PMS2 PARD6A 26496610 biogrid,intact exp P P P P P P P P P P P P P P P P P P P P WDR83 PARD6A 23439680 biogrid exp GP GP G G G GP G GP P G GP GP GP GP GP GP G GP G P GP G P GP GP GP GP G VHL PARD6A 17101696 biogrid exp, ortho G G G G G G G G G G GP GP GP G G G G G P G GP GP G G G G GP G DVL2 PARD6A 19888210,19379695 hprd,i2d,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PRKCZ PARD6A 17335965,16189514,11260256,12813044,17350623,14676191,10873802,15254234,25852190,17057644, 25402006, 21836163, 16082366 innatedb,hprd,biogrid,mint,intact,bci exp, ortho, pred G GP G GP G GP GP G GP GP GP GP G GP GP GP G P GP GP P GP GP GP GP SMURF2 PARD6A 19379695, 25402006 intact exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G LLGL1 PARD6A 14676191,26496610, 25402006 biogrid,intact exp, ortho, pred GP P G P GP G GP GP G P GP GP GP G GP GP GP GP G P GP GP GP P P GP GP G TGFBR1 PARD6A 15761148,15761153, 25402006 hprd,biogrid,i2d exp, ortho, pred GP G G G GP GP G GP GP G GP GP GP G G GP GP G G G G G G GP G GP G G SMURF1 PARD6A 21262463,15761148, 25402006 biogrid exp, ortho, pred G GP G G GP GP G G GP G GP G GP G G G GP GP G G P G G G G GP G GP G MAP2K5 PARD6A 12813044, 25402006 hprd,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP P GP GP G GP GP GP P G P GP GP GP GP GP GP GP G PARD3 PARD6A 22883624,14676191,12459187,26496610,11257119,17057644, 25402006, 23023127, 21836163 hprd,biogrid,i2d,mint,intact exp, ortho, pred G G G G GP GP G G GP G GP GP GP G G GP GP G GP G P G GP G GP GP GP GP G PRKCI PARD6A 16189514,11260256,16861740,21516116,12813044,25416956,14676191,15590654,26496610,11257119,17057644, 25402006, 23023127, 16082366 innatedb,hprd,biogrid,i2d,mint,intact,bci exp, ortho, pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G P GP G G GP G GP GP G ECT2 PARD6A 15254234, 21836163 hprd,biogrid exp, pred G G G G G G G G G G PAK1 PARD6A 20007894, 25402006, 21836163 i2d exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G ARHGEF11 PARD6A 25402006, 23023127 bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G CRB3 PARD6A 14718572, 21836163 hprd exp, pred G GP P P GP GP GP GP P GP G G G P GP P GP P LLGL2 PARD6A 14676191,26344197,26496610,20360068, 25402006, 21836163 biogrid,intact exp, pred GP GP G G G GP GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G RHOQ PARD6A 10934474, 25402006 hprd,biogrid,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDC42 PARD6A 14676191,10873802,11260256,12606577,10934474, 25402006, 21836163 innatedb,hprd,biogrid,i2d,intact,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G MPP5 PARD6A 12545177, 21836163 biogrid exp, pred GP G G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP G GP GP G YWHAZ PARD6A 14676191, 25402006 hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6A ASH1L 26496610, 21836163 biogrid,intact exp, pred GP GP G G GP GP G G GP G G G GP G G G GP GP GP G P GP GP G G G G GP G CDH5 PARD6A 17057644, 25402006 innatedb,hprd,mint,intact exp, pred GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G YWHAH PARD6A 14676191, 25402006 hprd,biogrid,intact,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP GP GP GP GP GP G DVL1 PARD6A 19888210, 23023127 i2d exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G RAC1 PARD6A 10873802,11260256, 25402006, 21836163 innatedb,hprd,biogrid,intact,bci exp, pred GP GP G G GP G G G GP G G G GP G G GP G G GP G P GP G GP GP G GP GP G CSNK1E PARD6A 19888210, 25402006 i2d exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP GP GP GP G PNMA1 PARD6A 14676191, 25402006 intact exp, pred G G G G G GP G G G G G G G G G G GP G G G G G G G GP G GP G PARD6A PLCB1 15782111, 21836163 hprd,i2d exp, pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G MARK2 PARD6A 14676191, 25402006, 21836163 hprd,biogrid exp, pred P P G G G GP GP GP G P P P G GP GP P G P GP GP P P GP GP P PARD6B PARD6A 14676191,26496610, 25402006, 23023127, 21836163, 16082366 hprd,biogrid,intact exp, pred P P P P P P GP G GP P G GP P P GP P GP GP P GP GP GP G MARK4 PARD6A 14676191, 25402006, 21836163 hprd,biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP G PLCB3 PARD6A 15782111, 25402006, 21836163 hprd,i2d,mint,intact exp, pred G G G G G GP G G G G G G G G G GP GP G G G G G G GP G G G G TJP1 PARD6A 11257119, 23023127 biogrid exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PKLR PARD6A ortho P G GP GP GP P GP GP MTSS1 PARD6A ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G SRSF1 PARD6A ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G FRMPD2 PARD6A 23023127 pred P P P P P P P P P P P ARHGAP32 PARD6A 25402006 pred GP GP G P GP G GP GP G GP G G G G GP GP G GP G P G GP GP GP G GP GP G SHROOM2 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G SMAD7 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G RHOA PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PLEKHA7 PARD6A 23023127 pred GP P P P G GP GP G GP GP GP P G GP GP G P P P GP GP P GP GP GFI1 PARD6A 23023127 pred P P G GP P P P P P P P GP P P P P P P P P GP P P PARD6A MAST1 23023127 pred P P G P GP G P G P P P P GP P P P P P P UBE2I PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G P GP GP G GP GP GP GP G TOM1 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6G PARD6A 25402006, 23023127, 16082366 pred G G G G G G G G G G GP G GP G G G G GP G G G GP G G G G GP G BRAF PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP P GP GP GP G P GP GP GP P GP GP GP G WASL PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PAK3 PARD6A 25402006 pred G G G G G GP G G G G G G GP G G GP G GP G P G G G G G G G G PARD6A TLN2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP P GP GP G BTK PARD6A 25402006 pred G G GP G G GP GP G G GP G TSC2 PARD6A 23023127 pred G GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G P G G G GP G GP GP G PRKCQ PARD6A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWC1 PARD6A 25402006 pred GP GP G G G GP G G GP G GP GP GP G G GP GP GP GP G P GP GP GP GP G GP GP G AKTIP PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G CDC42EP1 PARD6A 25402006 pred G GP G P GP G G GP G GP GP GP G G GP GP GP GP G P G GP P GP G GP GP G AQP9 PARD6A 21836163 pred G G G G G G MAPK8IP2 PARD6A 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP GP GP GP G CTNNB1 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP G GP G GP GP G LNX1 PARD6A 23023127 pred GP G G GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP G GP P GP GP THY1 PARD6A 23023127 pred G G G G G GP G G G G GP G G G G G GP G G G G G GP G G G G G SMAD3 PARD6A 23023127 pred GP GP G G G GP G G G G G G GP GP G G GP G GP G P G G G G G G G G PPP1R9B PARD6A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G PAK2 PARD6A 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP G G P G GP GP GP GP GP G G JUP PARD6A 25402006 pred GP G G G G G G G GP G GP GP G G G GP G G GP G P GP GP G GP G GP G G RUSC2 PARD6A 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G P GP GP P G P P GP GP GP GP GP GP G FRMD5 PARD6A 23023127 pred P GP G P GP G GP P G P P P P P GP G P G P P P P P P P P PDPK1 PARD6A 25402006, 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G P GP GP G GP GP GP GP G DLG2 PARD6A 23023127 pred P GP G GP G G P P GP GP P G P P P PACSIN1 PARD6A 23023127 pred G GP G G P G P GP G APOBEC3G PARD6A 23023127 pred G GP G GP G GP GP G GP GP GP GP G G G G G G GP G GP G GP G GP G PARD6A UBQLN2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G CDHR1 PARD6A 23023127 pred P P P GP G P P P P P P P P P P P P G P P LIMK2 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G SPTB PARD6A 23023127 pred G G G G GP GP G GP G GP G G G G GP GP G G GP G G G PARD6A ARHGEF4 25402006 pred G GP G G GP GP G P GP G P GP G G GP GP GP GP G G GP G GP G GP G NCF2 PARD6A 25402006 pred G G GP G G G GP GP G G G G G G G GP G G DOCK1 PARD6A 25402006 pred GP G G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP G GP GP GP GP G KLC2 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6A CAMSAP3 23023127 pred P G GP GP G G GP GP G GP GP P GP G P G GP GP GP GP OPHN1 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G SSH1 PARD6A 21836163 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G G G P GP G G GP GP GP GP G TULP1 PARD6A 23023127 pred G G G G G G RAF1 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G STAU1 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PDZD7 PARD6A 23023127 pred G G G G G G G G G G G G G G G G G G G ARHGEF17 PARD6A 21836163 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G P GP G GP GP G GP GP G RIT2 PARD6A 21836163 pred G G G G G PRKCA PARD6A 25402006 pred G GP G G GP GP G GP GP G GP G G GP G GP GP G GP G P G G GP GP G GP GP G SORBS1 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP GP GP G GP GP G RAC3 PARD6A 25402006 pred P P P P P P P P P P P P P P P P P PTK2B PARD6A 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G P GP G G GP G GP GP G MPZ PARD6A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G ARHGEF7 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP G GP GP GP GP GP G AXIN1 PARD6A 25402006 pred GP GP G GP GP G P GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G GPR98 PARD6A 23023127 pred G G G G G G G G G G G G G G SRC PARD6A 25402006 pred GP GP G GP GP G G GP G G G G GP GP G G G GP GP G GP GP GP GP G CDC42EP2 PARD6A 25402006 pred GP GP G G GP GP G GP GP G P GP G G GP GP GP GP P GP P GP G GP P G EPB41L4B PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP GP GP P GP GP G CDC42BPA PARD6A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G EPB41L5 PARD6A 23023127 pred G GP G G GP GP G G G G GP GP G G G GP GP G GP G P G G G GP P GP GP G CHN2 PARD6A 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP P P GP GP GP P G PARD6A CORO1C 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PDZD4 PARD6A 23023127 pred P G P GP G P G P P P GP GP G P P P GP P P G ACTN2 PARD6A 23023127 pred P P P GP GP P G P P P P GP P G P P P GP GP P P SLC9A3R2 PARD6A 25402006 pred P P P G GP GP GP G GP P P P GP GP GP PARD6A CD2AP 23023127 pred GP GP G GP P G G GP GP GP GP GP G GP GP G GP G P GP GP G GP GP GP GP YWHAE PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G YWHAB PARD6A 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G IQGAP2 PARD6A 25402006 pred GP GP G GP P G GP GP GP GP GP G G GP P GP GP G P GP GP GP G GP GP G ITSN1 PARD6A 25402006 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G G G P G GP GP GP G GP GP G NES PARD6A 25402006 pred G G G GP G GP GP G GP G G G G G GP G G G G GP G G G G G PARD6A WASF2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G NCF4 PARD6A 16082366 pred G G G GP G GP GP G G G GP G NCF4 PARD6A 16082366 pred G G G GP G GP GP G G G GP G YWHAG PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6A MAP3K2 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G P GP GP GP GP G GP GP G DSP PARD6A 23023127 pred G G G G G G G GP G G G G G G G G G G GP G P G GP G G G GP G G NEXN PARD6A 21836163 pred GP GP G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P G GP GP GP GP GP GP G PLEC PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G SPTBN2 PARD6A 23023127 pred GP GP G GP G G GP GP P P GP GP G GP GP P P P GP BCAR1 PARD6A 23023127 pred GP GP G P GP G GP GP G GP GP GP GP GP GP GP GP G P GP GP GP GP GP GP GP G THOC5 PARD6A 23023127 pred G GP G G G GP G G GP G GP G GP G G GP GP G G G P GP G GP GP G GP G G PARD6A TLN1 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G YWHAQ PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP G GP GP GP GP G TIAM1 PARD6A 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP P GP GP GP GP G CTNNA1 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6A NCKIPSD 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP G GP GP GP GP GP G NOS2 PARD6A 25402006 pred P P G G P G P GP P P P P GP GP G GP G P P P P GP P P G VAV1 PARD6A 25402006 pred GP GP G GP GP G P P G P GP GP GP G GP GP G GP G P G GP P P GP GP GP G SUPT5H PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G MSN PARD6A 21836163 pred GP GP G G GP GP G G GP G GP G GP GP G G GP GP GP G P GP GP G G GP G GP G UBL7 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP G GP GP GP GP G IQGAP1 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP G GP GP GP GP G PSIP1 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G CPVL PARD6A 21836163 pred G G G G GP G G GP G G GP G GP G G G G G GP G P G G G G GP G GP G NUMB PARD6A 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6A USH1C 23023127 pred P P G P GP G GP GP G GP GP P P GP GP GP GP G P P P GP GP P GP P G TGFB3 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP G PTPRB PARD6A 25402006 pred G GP G GP G GP G G GP GP GP GP G GP GP G GP G GP G G GP GP GP P G PBRM1 PARD6A 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G P G GP GP GP G GP GP G PVRL1 PARD6A 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G P GP G G GP G GP GP G NBR1 PARD6A 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP G GP GP G SPTBN4 PARD6A 23023127 pred P G GP G P GP G P P P P GP P G P P GP P P GP PRKCD PARD6A 25402006 pred GP GP G G GP GP G GP GP GP P GP GP G GP GP GP GP P GP GP P GP GP GP GP G ARHGDIA PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD3B PARD6A 23023127, 21836163 pred G GP G GP G G GP G GP GP GP G G GP GP G GP G P GP GP GP GP G GP G G ARAF PARD6A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G CTNND1 PARD6A 25402006 pred P P P P P P P P P P P P P P P P P P P P P WWP2 PARD6A 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP G GP GP G PARD6A EPB41L3 23023127 pred G GP G GP G G GP G GP G GP G GP GP GP GP G P G GP G GP USP44 PARD6A 23023127 pred P P P P P P P P P P P P P GP G P P P P P P GP RACGAP1 PARD6A 25402006 pred GP G G GP G G G GP G GP G G GP G GP G G G P G G G GP G GP GP G NF2 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G MCF2L PARD6A 25402006 pred GP G G G GP GP G G GP G GP GP GP GP G G GP G GP G P GP GP GP G GP GP G G PARD6A F11R 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP G GP GP GP GP G RIT1 PARD6A 21836163 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP GP GP GP GP GP G RASA1 PARD6A 23023127 pred GP G G G GP GP G G G G G G G G G G GP G G G P G G G G G GP G G SYNJ2BP PARD6A 23023127 pred G GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP G GP G GP GP G PARD6A NUMBL 23023127 pred G GP G G G GP G G GP G GP G G G G G GP G G G P G G G G G G GP G SQSTM1 PARD6A 25402006 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G P GP GP GP GP GP GP GP G GRIP2 PARD6A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G PARD6A SH3GLB2 23023127 pred G GP G G G GP G G GP G GP G GP G G GP G GP G P G G G G GP GP GP G PARD6A BAIAP2 25402006 pred P P G G GP GP G GP P G GP GP GP GP P GP GP GP G P GP P P P P GP GP G WASF1 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP P GP G GP GP GP P G P GP GP P GP GP GP GP G PARD6A PAK7 25402006 pred GP G GP P P G P P P GP GP G P P P P P G USH2A PARD6A 23023127 pred PARVB PARD6A 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G PARK2 PARD6A 23023127 pred P GP G P GP G GP GP G GP P P G P GP GP P G P GP GP GP P GP G SCPEP1 PARD6A 21836163 pred G GP G G G GP G G GP G GP GP GP GP G GP GP G GP G P GP GP G GP GP GP GP G PIK3R1 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G CXADR PARD6A 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G P GP GP GP GP G GP GP G TNK2 PARD6A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PARD6A ABI2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SLC25A16 PARD6A 21836163 pred G G G G GP GP G GP G G GP GP GP G G GP GP GP GP G G G G GP G GP GP G MARK3 PARD6A 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G P GP GP G GP G GP GP G ACTN3 PARD6A 23023127 pred G G G G G G G G G G G G G G G G G G G G G TRIM29 PARD6A 25402006 pred GP G G G G GP G G G G G G GP G G GP G GP G P GP GP G G G G G G PARD6A GRIP1 23023127 pred P P G P GP G P GP G GP P P P G P GP P G P GP GP P P GP GP P CDC42EP5 PARD6A 25402006 pred G G P G G GP GP G G G GP P G G G G G GP G GP GP G THOC7 PARD6A 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G P GP GP G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9NPB6 - 14676191 - C 9 Q9NPB6 - 15782111 - C 3 Q9NQ66 Q9NPB6 - 15782111 - X 2 Q9NPB6 Q01970 - 15782111 - X 2 Q9NPB6 - 14676191 - C 13 Q9NPB6 - 14676191 - C 19 Q9NPB6 - 15782111 - C 3 Q9NPB6 - 15590654 - X 2 Q9NPB6 anti tag coimmunoprecipitation 15048131 association C 6 Q9NPB6 coimmunoprecipitation 15782111 association C 3 Q9NPB6 anti tag coimmunoprecipitation 12545177 association C 3 Q9NPB6 coimmunoprecipitation 17057644 association C 4 Q9NPB6 coimmunoprecipitation 15782111 association C 3 Q9NPB6 coimmunoprecipitation 17057644 association C 3 Q9NPB6 luminescence based mammalian interactome mapping 15761148 association C 3 Q9NPB6 anti tag coimmunoprecipitation 15761148 association C 3 Q9NPB6 anti tag coimmunoprecipitation 14676191 association C 9 Q9NPB6 anti tag coimmunoprecipitation 14676191 association C 19 Q9NPB6 tandem affinity purification 20360068 physical association C 5 A4D2P1 Q9NPB6 two hybrid 11260256 physical association X 2 A4D2P1 Q9NPB6 pull down 11260256 physical association X 2 O14641 Q9NPB6 anti bait coimmunoprecipitation 19379695 physical association X 2 Q8TEW0 Q9NPB6 coimmunoprecipitation 11257119 physical association X 2 Q8TEW0 Q9NPB6 coimmunoprecipitation 11257119 physical association X 2 Q8TEW0 Q9NPB6 anti tag coimmunoprecipitation 14676191 physical association X 2 Q8TEW0 Q9NPB6 anti tag coimmunoprecipitation 14676191 physical association X 2 Q8TEW0 Q9NPB6 anti bait coimmunoprecipitation 17057644 physical association X 2 Q9HAU4 Q9NPB6 anti bait coimmunoprecipitation 19379695 physical association X 2 Q9NPB6 A0A024R1K7 anti tag coimmunoprecipitation 14676191 physical association X 2 Q9NPB6 Q01970 anti tag coimmunoprecipitation 15782111 physical association X 2 Q9NPB6 Q01970 anti bait coimmunoprecipitation 15782111 physical association X 2 Q9NPB6 Q8NI35 pull down 17057644 physical association X 2 Q9NPB6 B2RCZ4 two hybrid prey pooling approach 25416956 physical association X 2 Q9NPB6 B2RCZ4 two hybrid prey pooling approach 25416956 physical association X 2 Q9NPB6 B2RCZ4 two hybrid array 25416956 physical association X 2 Q9NPB6 B2RCZ4 two hybrid array 25416956 physical association X 2 Q9NPB6 B2RCZ4 validated two hybrid 25416956 physical association X 2 P10687 Q9NPB6 anti tag coimmunoprecipitation 15782111 physical association X 2 P10687 Q9NPB6 anti bait coimmunoprecipitation 15782111 physical association X 2 Q9NPB6 anti tag coimmunoprecipitation 14676191 association C 13 Q9NPB6 coimmunoprecipitation 11257119 association C 3 Q9NPB6 anti tag coimmunoprecipitation 14676191 association C 11 Q8ND90 Q9NPB6 anti tag coimmunoprecipitation 14676191 physical association X 2 Q8ND90 Q9NPB6 anti tag coimmunoprecipitation 14676191 physical association X 2 P33151 Q9NPB6 pull down 17057644 physical association X 2 P33151 Q9NPB6 anti bait coimmunoprecipitation 17057644 physical association X 2 P33151 Q9NPB6 anti bait coimmunoprecipitation 17057644 physical association X 2 P33151 Q9NPB6 anti tag coimmunoprecipitation 17057644 physical association X 2 Q9NPB6 A0A024RAE4 two hybrid 10934474 physical association X 2 Q9NPB6 A0A024RAE4 two hybrid 10934474 physical association X 2 Q9NPB6 P41743 two hybrid 11257119 physical association X 2 Q9NPB6 P41743 two hybrid 11257119 physical association X 2 Q9NPB6 P41743 two hybrid 11260256 physical association X 2 Q9NPB6 A0A024RAE4 two hybrid 11260256 physical association X 2 Q9NPB6 Q05513 two hybrid 11260256 physical association X 2 Q9NPB6 A0A024RAE4 pull down 11260256 physical association X 2 Q9NPB6 P41743 anti tag coimmunoprecipitation 14676191 physical association X 2 Q9NPB6 A0A024RAE4 anti tag coimmunoprecipitation 14676191 physical association X 2 Q9NPB6 P41743 anti tag coimmunoprecipitation 14676191 physical association X 2 Q9NPB6 A0A024RAE4 anti tag coimmunoprecipitation 14676191 physical association X 2 Q9NPB6 P41743 x-ray crystallography 15590654 direct interaction X 2 Q9NPB6 P41743 two hybrid pooling approach 16189514 physical association X 2 Q9NPB6 Q05513 two hybrid pooling approach 16189514 physical association X 2 Q9NPB6 Q05513 imaging technique 17057644 colocalization X 2 Q9NPB6 P41743 anti bait coimmunoprecipitation 17057644 physical association X 2 Q9NPB6 Q05513 anti tag coimmunoprecipitation 17057644 physical association X 2 Q9NPB6 Q05513 anti tag coimmunoprecipitation 17350623 physical association X 2 Q9NPB6 P41743 two hybrid 21516116 physical association X 2 Q12799 Q9NPB6 two hybrid 10934474 physical association X 2 Q12799 Q9NPB6 two hybrid 10934474 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TUBG1 PARD6A MI:0004(affinity chromatography technology) 23469015 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_258177 prey bait CDH5 PARD6A MI:0493(in vivo)|MI:0493(in vivo)|MI:0493(in vivo)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique) 17057644 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|MI:0468(hprd)|MI:0468(hprd)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact) HPRD_39863|HPRD_39862|HPRD_32031|MINT_84953|UniProt_88975|UniProt_88985|MINT_52457|MINT_84951|MINT_52455|UniProt_88990|MINT_52464|MINT_52451|MINT_84960|MINT_84947|UniProt_88978 -|-|-|bait|bait|bait|bait|bait|bait|prey|bait|prey|bait|prey|bait -|-|-|prey|prey|prey|prey|prey|prey|bait|prey|bait|prey|bait|prey YWHAZ PARD6A MI:0493(in vivo)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_8851|BIOGRID_150418 -|bait -|prey MAP2K5 PARD6A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 12813044 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0407(direct interaction) (biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_216851|BIOGRID_216863|HPRD_32285|BIOGRID_216862 prey|bait|-|bait bait|prey|-|prey SMURF1 PARD6A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15761148,21262463 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_160758|BIOGRID_199810 bait|prey prey|bait FBXO31 PARD6A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23469015 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_258175|BIOGRID_258176 bait|prey prey|bait MARK4 PARD6A MI:0004(affinity chromatography technology)|MI:0493(in vivo) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_150342|HPRD_14248 prey|- bait|- TJP1 PARD6A MI:0004(affinity chromatography technology) 11257119 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_210981 prey bait LLGL1 PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_73668|BIOGRID_150449 prey|prey bait|bait ARHGAP17 PARD6A MI:0004(affinity chromatography technology) 16678097 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_216809 bait prey LLGL2 PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 14676191,20360068 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid) UniProt_73668|BIOGRID_150454|BIOGRID_150951 prey|prey|bait bait|bait|prey TCP10 PARD6A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 10934474 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (intact)|(intact)|(intact)|MI:0468(hprd)|(intact) UniProt_66494|UniProt_66498|UniProt_160805|HPRD_3501|UniProt_160809 prey|prey|prey|-|prey bait|bait|bait|-|bait Q5T2E2 PARD6A MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:0() taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_69644|MINT_40271 bait|bait prey|prey DGKZ PARD6A MI:0428(imaging technique) 17350623 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_119007 bait prey PRKCH PARD6A MI:0493(in vivo) 17335965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_32244 - - GLS PARD6A MI:0493(in vivo) 12629547 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_31359 - - RPAP3 PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_73668|BIOGRID_150450 prey|prey bait|bait PNMA1 PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_73705|UniProt_73714 bait|bait prey|prey TGFB1 PARD6A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15761148 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_199808|BIOGRID_199809 bait|prey prey|bait PLCB3 PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo)|MI:0007(anti tag coimmunoprecipitation) 15782111 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0468(hprd)|MI:0471(mint) UniProt_80991|MINT_61679|UniProt_80995|MINT_32800|UniProt_181821|MINT_32796|UniProt_181817|HPRD_17854|MINT_61675 prey|bait|bait|bait|bait|prey|prey|-|prey bait|prey|prey|prey|prey|bait|bait|-|bait INADL PARD6A MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique) 17057644 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|MI:0471(mint) MINT_84952|UniProt_88986|MINT_52456 bait|bait|bait prey|prey|prey PRKCZ PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo)|MI:0492(in vitro)|MI:0493(in vivo)|MI:0428(imaging technique)|MI:0007(anti tag coimmunoprecipitation)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0428(imaging technique)|MI:0493(in vivo)|MI:0428(imaging technique)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0428(imaging technique) 11260256,12813044,14676191,15254234,16189514,17057644,17350623 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|-|-|-|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0468(hprd)|MI:0468(hprd)|MI:0468(hprd)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|(biogrid)|MI:0471(mint) UniProt_73668|HPRD_39864|HPRD_39239|HPRD_39867|MINT_52459|UniProt_90006|UniProt_88971|MINT_84955|UniProt_88991|MINT_52452|UniProt_68456|UniProt_154020|BIOGRID_216853|BIOGRID_216850|BIOGRID_81198|BIOGRID_85980|MINT_53064|HPRD_2161|MINT_84948|BIOGRID_114494|BIOGRID_150453|MINT_86618 prey|-|-|-|neutral component|bait|neutral component|neutral component|prey|prey|bait|unspecified role|bait|prey|bait|prey|bait|-|prey|prey|prey|bait bait|-|-|-|neutral component|prey|neutral component|neutral component|bait|bait|prey|unspecified role|prey|bait|prey|bait|prey|-|bait|bait|bait|prey RAC1 PARD6A MI:0493(in vivo)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 10873802,11260256 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact) HPRD_10255|BIOGRID_105818|BIOGRID_114516|BIOGRID_114504|BIOGRID_105816|UniProt_68460|UniProt_68473 -|prey|prey|prey|prey|bait|prey -|bait|bait|bait|bait|prey|bait TGFBR1 PARD6A MI:0493(in vivo) 15761153 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17855 - - CDC42 PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid) 10873802,10934474,11260256,14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(biogrid)|(intact)|MI:0468(hprd)|(intact) UniProt_73668|BIOGRID_105819|BIOGRID_105817|UniProt_66495|BIOGRID_105613|UniProt_66499|UniProt_73677|BIOGRID_150448|BIOGRID_114505|UniProt_160810|UniProt_73701|UniProt_160806|BIOGRID_114517|UniProt_68470|HPRD_17533|UniProt_68461 prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|-|bait bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|prey|bait|bait|bait|-|prey RHOQ PARD6A MI:0018(two hybrid)|MI:0018(two hybrid) 10934474 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_13835|BIOGRID_105614 -|prey -|bait NRF1 PARD6A MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_295005 bait prey WDR92 PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_73668|BIOGRID_150456 prey|prey bait|bait CRB3 PARD6A MI:0493(in vivo) 14718572 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_14251 - - PARD6A SUGT1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_73668|BIOGRID_150457 bait|bait prey|prey YWHAH PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|- (intact)|(intact)|(biogrid)|MI:0468(hprd) UniProt_73662|UniProt_73688|BIOGRID_150410|HPRD_8729 bait|unspecified role|bait|- prey|unspecified role|prey|- SMURF2 PARD6A MI:0493(in vivo)|MI:0493(in vivo)|MI:0729(luminescence based mammalian interactome mapping) 19379695 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0915(physical association) MI:0468(hprd)|MI:0468(hprd)|(intact) HPRD_40141|HPRD_40143|UniProt_98599 -|-|bait -|-|prey PARD6A PLCB1 MI:0493(in vivo) 15782111 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17852 - - PARD6A PIH1D1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_73668|BIOGRID_150455 bait|bait prey|prey UBC PARD6A MI:0004(affinity chromatography technology) 23469015 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_258178 prey bait PARD6A PDRG1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_73668|BIOGRID_150452 bait|bait prey|prey DVL2 PARD6A MI:0493(in vivo)|MI:0493(in vivo)|MI:0493(in vivo)|MI:0493(in vivo)|MI:0729(luminescence based mammalian interactome mapping) 19379695 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|-|-|MI:0915(physical association) MI:0468(hprd)|MI:0468(hprd)|MI:0468(hprd)|MI:0468(hprd)|(intact) HPRD_40142|HPRD_40141|HPRD_40143|HPRD_33466|UniProt_98598 -|-|-|-|prey -|-|-|-|bait MARK2 PARD6A MI:0493(in vivo)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_7188|BIOGRID_150341 -|prey -|bait PARD3 PARD6A MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0428(imaging technique)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0428(imaging technique)|MI:0493(in vivo)|MI:0428(imaging technique)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 11257119,12459187,14676191,17057644,22883624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|(intact) UniProt_69342|UniProt_73668|UniProt_73661|BIOGRID_110295|UniProt_69341|UniProt_69340|UniProt_88994|UniProt_73675|BIOGRID_259745|BIOGRID_150458|MINT_52465|HPRD_13986|MINT_84961|BIOGRID_210980|UniProt_73672 prey|prey|bait|bait|prey|prey|prey|prey|bait|prey|prey|-|prey|prey|bait bait|bait|prey|prey|bait|bait|bait|bait|prey|bait|bait|-|bait|bait|prey VHL PARD6A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17101696 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_214457|BIOGRID_214454 bait|prey prey|bait PRKCG PARD6A MI:0493(in vivo) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_2106 - - MPP5 PARD6A MI:0004(affinity chromatography technology) 12545177 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_108735 prey bait ECT2 PARD6A MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 15254234 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|- MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) HPRD_39239|BIOGRID_85981|BIOGRID_85979|BIOGRID_85978|BIOGRID_78048|HPRD_16888 -|prey|bait|prey|bait|- -|bait|prey|bait|prey|- PARD6B PARD6A MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 14676191 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|-|MI:0915(physical association) (intact)|(intact)|(biogrid)|MI:0468(hprd)|(biogrid) UniProt_73668|UniProt_73667|BIOGRID_150435|HPRD_14252|BIOGRID_150451 prey|bait|bait|-|prey bait|prey|prey|-|bait PRKCI PARD6A MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0493(in vivo)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0428(imaging technique) 11257119,11260256,12813044,14676191,15590654,16189514,16861740,17057644,21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|(biogrid)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact) UniProt_69342|UniProt_73668|MINT_84954|MINT_52458|HPRD_5233|BIOGRID_284228|BIOGRID_216859|UniProt_68455|UniProt_151497|BIOGRID_216856|BIOGRID_216849|UniProt_114799|BIOGRID_216852|UniProt_73678|UniProt_73676|UniProt_80625|BIOGRID_210977|BIOGRID_150447|MINT_65819|MINT_36667|BIOGRID_210979|BIOGRID_78639|BIOGRID_210978|UniProt_69339|UniProt_69338|UniProt_88976 prey|prey|bait|bait|-|bait|prey|bait|unspecified role|bait|prey|bait|bait|bait|prey|neutral component|prey|prey|bait|bait|bait|bait|prey|bait|bait|bait bait|bait|prey|prey|-|prey|bait|prey|unspecified role|prey|bait|prey|prey|prey|bait|neutral component|bait|bait|prey|prey|prey|prey|bait|prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality B4DDV3 PARD6A 26496610 0007 HT KIF1B PARD6A 26496610,26496610 0007,0004 HT GLUD1 PARD6A 26496610,26496610 0007,0004 HT PRDX3 PARD6A 26496610,26496610 0007,0004 HT PRKCI PARD6A 12813044,14676191,17057644,26496610,26496610,11257119,11257119,16861740,11257119,14676191,14676191,12813044 0018,0007,0006,0004,0007,0018,0019,0096,0004,0004,0019,0004 LC,HT SMARCA4 PARD6A 26496610,26496610 0007,0004 HT PLXNA3 PARD6A 26496610,26496610 0007,0004 HT TTC3 PARD6A 26496610,26496610 0007,0004 HT PMS2 PARD6A 26496610,26496610 0007,0004 HT EPHB4 PARD6A 26496610,26496610 0007,0004 HT CDC42 PARD6A 14676191,11260256,10873802,10873802,10873802,11260256,14676191,14676191 0007,0096,0096,0018,0004,0018,0004,0019 LC RAC1 PARD6A 11260256,10873802,10873802,11260256 0096,0096,0004,0018 LC PRKCZ PARD6A 25852190,15254234,14676191,14676191,10873802,25852190,10873802,17057644,17350623,17057644 0007,0096,0004,0007,0096,0004,0007,0007,0007,0428 HT,LC ORC2 PARD6A 26496610,26496610 0007,0004 HT TP53BP2 PARD6A 26496610,26496610 0007,0004 HT ARID5B PARD6A 26496610,26496610 0007,0004 HT LLGL1 PARD6A 26496610,14676191,14676191,26496610 0007,0007,0004,0004 HT,LC LLGL2 PARD6A 14676191,14676191,26496610,26496610,20360068,20360068,26344197 0007,0004,0004,0007,0004,0676,0401 LC,HT NOL8 PARD6A 26496610,26496610 0007,0004 HT DPP9 PARD6A 26496610,26496610 0007,0004 HT SIRT6 PARD6A 26496610 0004 HT RASSF8 PARD6A 26496610,26496610 0007,0004 HT PARD3 PARD6A 14676191,22883624,17057644,14676191,26496610,12459187,14676191,26496610 0007,0004,0006,0004,0007,0004,0019,0004 LC,HT LRCH3 PARD6A 26496610,26496610 0007,0004 HT PIK3R4 PARD6A 26496610,26496610 0007,0004 HT PARD6B PARD6A 26496610,14676191,14676191,26496610 0007,0007,0004,0004 HT,LC TMEM126A PARD6A 26496610,26496610 0007,0004 HT ELP3 PARD6A 26496610,26496610 0007,0004 HT SMURF1 PARD6A 15761148,21262463 0004,0004 LC PARD6A ASH1L 26496610,26496610 0007,0004 HT PARD6A ZAK 26496610,26496610 0007,0004 HT B4DDV3 PARD6A 26496610 0007 HT KIF1B PARD6A 26496610,26496610 0007,0004 HT GLUD1 PARD6A 26496610,26496610 0007,0004 HT PRDX3 PARD6A 26496610,26496610 0007,0004 HT PRKCI PARD6A 26496610,26496610 0004,0007 HT SMARCA4 PARD6A 26496610,26496610 0007,0004 HT PLXNA3 PARD6A 26496610,26496610 0007,0004 HT TTC3 PARD6A 26496610,26496610 0007,0004 HT PMS2 PARD6A 26496610,26496610 0007,0004 HT EPHB4 PARD6A 26496610,26496610 0007,0004 HT PRKCZ PARD6A 25852190,25852190 0007,0004 HT ORC2 PARD6A 26496610,26496610 0007,0004 HT TP53BP2 PARD6A 26496610,26496610 0007,0004 HT ARID5B PARD6A 26496610,26496610 0007,0004 HT LLGL1 PARD6A 26496610,26496610 0007,0004 HT LLGL2 PARD6A 26496610,26496610,26344197 0004,0007,0401 HT NOL8 PARD6A 26496610,26496610 0007,0004 HT DPP9 PARD6A 26496610,26496610 0007,0004 HT SIRT6 PARD6A 26496610 0004 HT RASSF8 PARD6A 26496610,26496610 0007,0004 HT PARD3 PARD6A 26496610,26496610 0007,0004 HT LRCH3 PARD6A 26496610,26496610 0007,0004 HT PIK3R4 PARD6A 26496610,26496610 0007,0004 HT PARD6B PARD6A 26496610,26496610 0007,0004 HT TMEM126A PARD6A 26496610,26496610 0007,0004 HT ELP3 PARD6A 26496610,26496610 0007,0004 HT PARD6A ASH1L 26496610,26496610 0007,0004 HT PARD6A ZAK 26496610,26496610 0007,0004 HT PRKCI PARD6A 12813044,14676191,17057644,11257119,11257119,16861740,11257119,14676191,14676191,12813044 0018,0007,0006,0018,0019,0096,0004,0004,0019,0004 LC CDC42 PARD6A 14676191,11260256,10873802,10873802,10873802,11260256,14676191,14676191 0007,0096,0096,0018,0004,0018,0004,0019 LC RAC1 PARD6A 11260256,10873802,10873802,11260256 0096,0096,0004,0018 LC PRKCZ PARD6A 15254234,14676191,14676191,10873802,10873802,17057644,17350623,17057644 0096,0004,0007,0096,0007,0007,0007,0428 LC LLGL1 PARD6A 14676191,14676191 0007,0004 LC LLGL2 PARD6A 14676191,14676191,20360068,20360068 0007,0004,0004,0676 LC PARD3 PARD6A 14676191,22883624,17057644,14676191,12459187,14676191 0007,0004,0006,0004,0004,0019 LC PARD6B PARD6A 14676191,14676191 0007,0004 LC SMURF1 PARD6A 15761148,21262463 0004,0004 LC B2RCZ4 PARD6A 25416956,25416956,25416956 1112,0397,1356 HT RHOQ PARD6A 10934474 0018 LC TUBG1 PARD6A 23469015 0401 LC TGFBR1 PARD6A 15761153 0019 HT PRKCI PARD6A 12813044,14676191,16189514,15590654,21516116,11257119,25416956,16189514,11257119,11257119,11260256,14676191,14676191,12813044 0018,0007,0398,0114,0018,0018,0018,0018,0019,0004,0018,0004,0019,0004 LC,HT CDC42 PARD6A 14676191,11260256,12606577,10873802,10873802,10873802,10934474,11260256,14676191,14676191 0007,0096,0018,0096,0018,0004,0018,0018,0004,0019 LC GRB2 PARD6A 25814554,25814554,25814554,25814554,25814554 0729,1356,0397,0018,0004 HT RAC1 PARD6A 11260256,11260256 0096,0018 LC PLCB3 PARD6A 15782111,15782111,15782111 0019,0007,0006 LC PRKCZ PARD6A 16189514,16189514,11260256,12813044,17335965 0398,0018,0018,0018,0018 HT,LC TCP10 PARD6A 10934474 0018 LC MAP2K5 PARD6A 12813044,12813044 0018,0004 LC LLGL2 PARD6A 26344197 0401 LC PARD3 PARD6A 14676191,14676191,11257119,11257119,14676191 0007,0004,0019,0018,0019 LC PIK3R3 PARD6A 25814554,25814554,25814554,25814554,25814554 0729,1356,0397,0018,0004 HT WDR83 PARD6A 23439680,23439680 0018,0004 LC CRB3 PARD6A 14718572 0018 LC ECT2 PARD6A 15254234,15254234,15254234 0096,0004,0018 LC PARD6A PLCB1 15782111 0019 LC PARD6A HEL-S-42 10934474 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NPB6 O14641 PARD6A DVL2 0.236 19379695 Q9NPB6 P60953 PARD6A CDC42 0.955 14676191,10934474,11260256,10873802 Q9NPB6 Q5XUX0 PARD6A FBXO31 0.376 23469015 Q9NPB6 Q9HAU4 PARD6A SMURF2 0.236 19379695 Q9NPB6 Q9HCE7 PARD6A SMURF1 0.376 15761148,21262463 Q9NPB6 B4DDV3 PARD6A B4DDV3 0.126 26496610 Q9NPB6 F5GZI3 PARD6A PARD3 {ECO:0000313|ENSEMBL:ENSP00000444429} 0.126 26496610 Q9NPB6 O60333 PARD6A KIF1B 0.126 26496610 Q9NPB6 P17081 PARD6A RHOQ 0.309 10934474 Q9NPB6 P23258 PARD6A TUBG1 0.126 23469015 Q9NPB6 P30048 PARD6A PRDX3 0.126 26496610 Q9NPB6 P53804 PARD6A TTC3 0.126 26496610 Q9NPB6 Q04917 PARD6A YWHAH 0.332 14676191 Q9NPB6 Q07157 PARD6A TJP1 0.126 11257119 Q9NPB6 Q12799 PARD6A TCP10 0.309 10934474 Q9NPB6 Q13163 PARD6A MAP2K5 0.623 12813044 Q9NPB6 Q6R327 PARD6A RICTOR 0.21 20978191 Q9NPB6 Q76FK4 PARD6A NOL8 0.126 26496610 Q9NPB6 Q7KZI7 PARD6A MARK2 0.126 14676191 Q9NPB6 Q8N3R9 PARD6A MPP5 0.21 12545177 Q9NPB6 Q8N6T7 PARD6A SIRT6 0.126 26496610 Q9NPB6 Q8ND90 PARD6A PNMA1 0.126 14676191 Q9NPB6 Q8NI35 PARD6A INADL 0.21 17057644 Q9NPB6 Q96L34 PARD6A MARK4 0.126 14676191 Q9NPB6 Q9H9T3 PARD6A ELP3 0.126 26496610 Q9NPB6 Q9HBD4 PARD6A SMARCA4 0.126 26496610 Q9NR48 Q9NPB6 ASH1L PARD6A 0.126 26496610 Q9NPB6 Q68EM7 PARD6A ARHGAP17 0.21 16678097 Q9NPB6 P05067 PARD6A APP 0.183 21244100 Q9NPB6 Q9H8V3 PARD6A ECT2 0.702 15254234 Q9NPB6 Q16825 PARD6A PTPN21 0.236 unassigned1304 Q9NPB6 Q14865 PARD6A ARID5B 0.236 26496610 Q9NPB6 Q13625 PARD6A TP53BP2 0.236 26496610 Q9NPB6 P51805 PARD6A PLXNA3 0.236 26496610 Q9NPB6 B2RCZ4 PARD6A B2RCZ4 0.416 25416956 Q9NPB6 P00367 PARD6A GLUD1 0.236 26496610 Q9NPB6 Q13416 PARD6A ORC2 0.236 26496610 Q9NPB6 P54278 PARD6A PMS2 0.236 26496610 Q9NPB6 P54760 PARD6A EPHB4 0.236 26496610 Q9NUG6 Q9NPB6 PDRG1 PARD6A 0.236 14676191 Q9NPB6 Q96II8 PARD6A LRCH3 0.236 26496610 Q9NPB6 Q86TI2 PARD6A DPP9 0.236 26496610 Q9NPB6 Q92569 PARD6A PIK3R3 0.523 25814554 Q9NPB6 Q8NHQ8 PARD6A RASSF8 0.236 26496610 Q9NPB6 Q9BRX9 PARD6A WDR83 0.454 23439680 Q9NPB6 Q96MX6 PARD6A WDR92 0.236 14676191 Q9NPB6 Q99570 PARD6A PIK3R4 0.236 26496610 Q9NPB6 Q9H6T3 PARD6A RPAP3 0.236 14676191 Q9NPB6 Q9H061 PARD6A TMEM126A 0.236 26496610 Q9Y2Z0 Q9NPB6 SUGT1 PARD6A 0.236 14676191 Q9NWS0 Q9NPB6 PIH1D1 PARD6A 0.236 14676191 Q9NYL2 Q9NPB6 ZAK PARD6A 0.236 26496610 Q9NPB6 P10687 PARD6A PLCB1 0.376 15782111 Q9NPB6 Q9BYG5 PARD6A PARD6B 0.554 14676191,26496610 Q9NPB6 Q62074 PARD6A PRKCI 0.236 26496610 Q9NPB6 P33151 PARD6A CDH5 0.507 17057644 Q9NPB6 Q15334 PARD6A LLGL1 0.416 14676191,26496610 Q9NPB6 Q6P1M3 PARD6A LLGL2 0.687 14676191,20360068,26344197,26496610 Q9NPB6 Q8TEW0 PARD6A PARD3 0.925 12459187,14676191,26496610,22883624,11257119,17057644 Q9NPB6 Q05513 PARD6A PRKCZ 0.964 17350623,14676191,16189514,11260256,17057644,12813044,25852190,15254234 Q9NPB6 P41743 PARD6A PRKCI 0.998 25416956,14676191,16189514,16861740,15590654,17057644,12813044,unassigned1304,26496610,11260256,11257119,21516116 Q9NPB6 P36897 PARD6A TGFBR1 0.376 15761148 Q9NPB6 P40337 PARD6A VHL 0.376 17101696 Q9NPB6 Q13574 PARD6A DGKZ 0.21 17350623 Q9NPB6 P62993 PARD6A GRB2 0.523 25814554 Q9NPB6 P63000 PARD6A RAC1 0.858 10873802,11260256 Q9NPB6 P63104 PARD6A YWHAZ 0.126 14676191 Q9NPB6 Q01970 PARD6A PLCB3 0.376 15782111

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 F2RL2 PARD6A MI:0362 inference MI:0461 interaction database DVL1 PARD6A MI:0362 inference MI:0461 interaction database DVL2 PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database GIPC1 PARD6A MI:0362 inference MI:0461 interaction database MTSS1 PARD6A MI:0362 inference MI:0461 interaction database KIF1B PARD6A MI:0045 experimental interaction detection MI:0461 interaction database NPHP4 PARD6A MI:0362 inference MI:0461 interaction database MPDZ PARD6A MI:0362 inference MI:0461 interaction database GFPT2 PARD6A MI:0362 inference MI:0461 interaction database AP2A2 PARD6A MI:0362 inference MI:0461 interaction database GLUD1 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database TGFB1 PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database APP PARD6A MI:0045 experimental interaction detection MI:0461 interaction database UBB PARD6A MI:0362 inference MI:1106 pathways database UBC PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RAC2 PARD6A MI:0362 inference MI:0461 interaction database RHOQ PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PRKCA PARD6A MI:0362 inference MI:0461 interaction database PRDX3 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PKLR PARD6A MI:0362 inference MI:0461 interaction database HNRNPH3 PARD6A MI:0362 inference MI:0461 interaction database HNRNPH1 PARD6A MI:0362 inference MI:0461 interaction database CDH5 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database TGFBR1 PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TGFBR2 PARD6A MI:0362 inference MI:0461,MI:1106 interaction database,pathways database VHL PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PRKCI PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HTT PARD6A MI:0362 inference MI:0461 interaction database VDAC2 PARD6A MI:0362 inference MI:0461 interaction database NUMB PARD6A MI:0362 inference MI:0461 interaction database SMARCA4 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PLXNA3 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database HNRNPF PARD6A MI:0362 inference MI:0461 interaction database TTC3 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PMS2 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database EPHB4 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database HNRNPH2 PARD6A MI:0362 inference MI:0461 interaction database RAC3 PARD6A MI:0362 inference MI:0461 interaction database CDC42 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database RPL27 PARD6A MI:0362 inference MI:0461 interaction database RHOA PARD6A MI:0362 inference MI:1106 pathways database RPS23 PARD6A MI:0362 inference MI:0461 interaction database RAB11A PARD6A MI:0362 inference MI:0461 interaction database FKBP1A PARD6A MI:0362 inference MI:1106 pathways database RPS27A PARD6A MI:0362 inference MI:1106 pathways database UBA52 PARD6A MI:0362 inference MI:1106 pathways database GRB2 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database RAC1 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database YWHAZ PARD6A MI:0045 experimental interaction detection MI:0461 interaction database GPSM2 PARD6A MI:0362 inference MI:0461 interaction database PLCB3 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database RASSF7 PARD6A MI:0362 inference MI:0461 interaction database TLE3 PARD6A MI:0362 inference MI:0461 interaction database YWHAH PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PRKCZ PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SRSF1 PARD6A MI:0362 inference MI:0461 interaction database TCP10 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database MAP2K5 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database ORC2 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database DCTN2 PARD6A MI:0362 inference MI:0461 interaction database DGKZ PARD6A MI:0045 experimental interaction detection MI:0461 interaction database TP53BP2 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database ARID5B PARD6A MI:0045 experimental interaction detection MI:0461 interaction database LLGL1 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database ADRM1 PARD6A MI:0362 inference MI:0461 interaction database FBXO31 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database ARHGAP17 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database LLGL2 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database RICTOR PARD6A MI:0045 experimental interaction detection MI:0461 interaction database RNF19B PARD6A MI:0362 inference MI:0461 interaction database ARHGEF18 PARD6A MI:0362 inference MI:1106 pathways database NOL8 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database MARK2 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database DPP9 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PTOV1 PARD6A MI:0362 inference MI:0461 interaction database KLHL7 PARD6A MI:0362 inference MI:0461 interaction database MPP5 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database SIRT6 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PNMA1 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database RASSF8 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database INADL PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PARD3 PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database GIPC3 PARD6A MI:0362 inference MI:0461 interaction database GIPC2 PARD6A MI:0362 inference MI:0461 interaction database PIK3R3 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database DVL3 PARD6A MI:0362 inference MI:0461 interaction database GCC1 PARD6A MI:0362 inference MI:0461 interaction database LRCH3 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database FEM1C PARD6A MI:0362 inference MI:0461 interaction database MARK4 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PRICKLE1 PARD6A MI:0362 inference MI:0461,MI:1106 interaction database,pathways database WDR92 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database PIK3R4 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database WDR83 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database FEM1A PARD6A MI:0362 inference MI:0461 interaction database PARD6B PARD6A MI:0045 experimental interaction detection MI:0461 interaction database TMEM126A PARD6A MI:0045 experimental interaction detection MI:0461 interaction database RPAP3 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database ECT2 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database ELP3 PARD6A MI:0045 experimental interaction detection MI:0461 interaction database SMURF2 PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SMURF1 PARD6A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database GOPC PARD6A MI:0362 inference MI:0461 interaction database PARD6A PLCB1 MI:0045 experimental interaction detection MI:0461 interaction database PARD6A ASH1L MI:0045 experimental interaction detection MI:0461 interaction database PARD6A ASAH2 MI:0362 inference MI:0461 interaction database PARD6A PDRG1 MI:0045 experimental interaction detection MI:0461 interaction database PARD6A RNF19A MI:0362 inference MI:0461 interaction database PARD6A PIH1D1 MI:0045 experimental interaction detection MI:0461 interaction database PARD6A ZAK MI:0045 experimental interaction detection MI:0461 interaction database PARD6A CGN MI:0362 inference MI:1106 pathways database PARD6A FEM1B MI:0362 inference MI:0461 interaction database PARD6A SUGT1 MI:0045 experimental interaction detection MI:0461 interaction database PARD6A F11R MI:0362 inference MI:1106 pathways database PARD6A NUMBL MI:0362 inference MI:0461 interaction database