Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 16 84785672 rs4783057 G A rs4783057 4.30E-04 GEMCITABINE|CYTARABINE MANNOSYLTRANSFERASES|PIGB PROTEIN, HUMAN|RNA, SMALL INTERFERING|DEOXYCYTIDINE Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 G,A intron GWASdb_drug 16 84786250 rs6564074 C A rs6564074 1.48E-04 GEMCITABINE|CYTARABINE MANNOSYLTRANSFERASES|PIGB PROTEIN, HUMAN|RNA, SMALL INTERFERING|DEOXYCYTIDINE Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 A intron GWASdb_drug 16 84796402 rs7205632 A T rs7205632 4.88E-04 GEMCITABINE|CYTARABINE MANNOSYLTRANSFERASES|PIGB PROTEIN, HUMAN|RNA, SMALL INTERFERING|DEOXYCYTIDINE Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 T intron GWASdb_drug 16 84801751 rs2641688 G A rs2641688 6.53E-04 GEMCITABINE|CYTARABINE MANNOSYLTRANSFERASES|PIGB PROTEIN, HUMAN|RNA, SMALL INTERFERING|DEOXYCYTIDINE Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 G intron GWASdb_drug 16 84741149 rs8045120 G T rs8045120 1.30E-04 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 16 84741343 rs3764286 C T rs3764286 8.79E-04 Parkinson's disease HPOID:0001300 DOID:14330 A intron GWASdb_trait 16 84750595 rs1862794 C T rs1862794 8.34E-04 Type 2 diabetes HPOID:0005978 DOID:9352 T intron GWASdb_trait 16 84750595 rs1862794 C T rs1862794 2.87E-04 Multiple complex diseases HPOID:0000118 NA T intron GWASdb_trait 16 84750816 rs41422347 T C rs41422347 1.19E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 16 84754898 rs12149617 G A rs12149617 1.48E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 16 84754898 rs12149617 G A rs12149617 3.91E-04 Coronary Artery Disease HPOID:0001677 DOID:3393 A intron GWASdb_trait 16 84769024 rs41386649 C T rs41386649 2.64E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 16 84771176 rs17763304 C T rs17763304 7.13E-04 Type 2 diabetes HPOID:0005978 DOID:9352 C intron GWASdb_trait 16 84771176 rs17763304 C T rs17763304 3.42E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 16 84771176 rs17763304 C T rs17763304 7.82E-04 Coronary Artery Disease HPOID:0001677 DOID:3393 C intron GWASdb_trait 16 84774120 rs4510001 T C rs4510001 5.71E-04 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 16 84774120 rs4510001 T C rs4510001 1.70E-04 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 16 84774436 rs744839 C T rs744839 9.72E-04 Type 2 diabetes HPOID:0005978 DOID:9352 C intron GWASdb_trait 16 84780907 rs11149680 C T rs11149680 0.0003 Normoxic and mild-hypoxic adaptation in populations residing at low and moderate altitudes HPOID:0002795 DOID:2841|DOID:3083 C intron GWASdb_trait 16 84781101 rs8051512 C G rs8051512 2.31E-04 Parkinson's disease HPOID:0001300 DOID:14330 G intron GWASdb_trait 16 84783658 rs16974538 T G rs16974538 3.10E-05 Cognitive performance HPOID:0100543 DOID:1561 T intron GWASdb_trait 16 84785378 rs17831494 G A rs17831494 8.06E-04 Type 2 diabetes HPOID:0005978 DOID:9352 A,G intron GWASdb_trait 16 84785378 rs17831494 G A rs17831494 9.03E-05 Multiple complex diseases HPOID:0000118 NA A,G intron GWASdb_trait 16 84785672 rs4783057 G A rs4783057 3.74E-04 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 G,A intron GWASdb_trait 16 84785672 rs4783057 G A rs4783057 4.30E-04 Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 G,A intron GWASdb_trait 16 84786250 rs6564074 C A rs6564074 1.93E-04 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 A intron GWASdb_trait 16 84786250 rs6564074 C A rs6564074 1.48E-04 Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 A intron GWASdb_trait 16 84786855 rs7186789 T G rs7186789 6.13E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 T intron GWASdb_trait 16 84796402 rs7205632 A T rs7205632 5.85E-04 Type 2 diabetes HPOID:0005978 DOID:9352 T intron GWASdb_trait 16 84796402 rs7205632 A T rs7205632 4.14E-04 Multiple complex diseases HPOID:0000118 NA T intron GWASdb_trait 16 84796402 rs7205632 A T rs7205632 4.88E-04 Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 T intron GWASdb_trait 16 84796603 rs12932018 A G rs12932018 6.00E-06 Response to mTOR inhibitor (everolimus) HPOID:0002665|HPOID:0005584|HPOID:0003002|HPOID:0100526|HPOID:0012114|HPOID:0100843 DOID:4450|DOID:1612|DOID:3908|DOID:2871|DOID:3068|DOID:0050746 A cds-synon GWASdb_trait 16 84801751 rs2641688 G A rs2641688 6.53E-04 Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 G intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000103194.15 USP10 609818