PTM - CPLM Gene Name UniProt ID Type Position Code RNF40; BRE1B; KIAA0661 O75150 Acetylation 20 K RNF40; BRE1B; KIAA0661 O75150 Ubiquitination 788 K RNF40; BRE1B; KIAA0661 O75150 Ubiquitination 189 K RNF40; BRE1B; KIAA0661 O75150 Ubiquitination 420 K RNF40; BRE1B; KIAA0661 O75150 Ubiquitination 457 K RNF40; BRE1B; KIAA0661 O75150 Ubiquitination 50 K RNF40; BRE1B; KIAA0661 O75150 Ubiquitination 264 K RNF40; BRE1B; KIAA0661 O75150 Ubiquitination 439 K

PTM - dbPAF Gene Name UniProt ID Position Type Species RNF40; BRE1B; KIAA0661 O75150 114 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 127 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 277 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 278 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 451 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 523 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 525 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 528 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 529 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 556 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 557 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 571 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 573 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 574 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 575 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 576 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 585 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 593 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 600 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 601 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 644 T Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 819 S Homo sapiens(Human) RNF40; BRE1B; KIAA0661 O75150 853 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O75150 K20-ac Acetylation GGSGPPEkkLSREEK O75150 K21-ac Acetylation GSGPPEkkLSREEKT O75150 K517-ac Acetylation EVQAEIGkLRAQAsG O75150 K562-ac Acetylation VstPDNRkEMAPVPG O75150 K686-ac Acetylation APKEQRDkVQLMAAE O75150 R201-m1 Methylation RVVEASDrLQRRVEE O75150 K795-m1 Methylation kLMSERIkANQIHKL O75150 K906-m1 Methylation EKESFNLkRAQEDIS O75150 S114-p Phosphorylation ALLRCHEsQGELSSA O75150 T127-p Phosphorylation SAPEAPGtQEGPTCD O75150 T277-p Phosphorylation TKVLEMEttVEDLQW O75150 T278-p Phosphorylation KVLEMEttVEDLQWD O75150 T451-p Phosphorylation EVIQLEDtLAQVRKE O75150 S523-p Phosphorylation GkLRAQAsGsAHStP O75150 S525-p Phosphorylation LRAQAsGsAHStPNL O75150 T529-p Phosphorylation AsGsAHStPNLGHPE O75150 S556-p Phosphorylation EGGPGPVstPDNRkE O75150 T557-p Phosphorylation GGPGPVstPDNRkEM O75150 T571-p Phosphorylation MAPVPGTtTTtTSVk O75150 T574-p Phosphorylation VPGTtTTtTSVkKEE O75150 S585-p Phosphorylation kKEELVPsEEDFQGI O75150 T593-p Phosphorylation EEDFQGItPGAQGPs O75150 S600-p Phosphorylation tPGAQGPssRGREPE O75150 S601-p Phosphorylation PGAQGPssRGREPEA O75150 T644-p Phosphorylation EKAKVEEtKRKESEL O75150 S819-p Phosphorylation EQVLGLKsQVDAQLL O75150 S853-p Phosphorylation EKELTLRsQALELNK O75150 K578-sm Sumoylation tTTtTSVkKEELVPs O75150 K189-ub Ubiquitination QGRMEFSkAAVSRVV O75150 K743-ub Ubiquitination QIEHLQRkLGATKQE O75150 K788-ub Ubiquitination EKDDANFkLMSERIk

PTM - dbPTM UniProt ID Position Code Type Resources References O75150 644 T Phosphorylation Swiss-Prot 1010711 17081983 O75150 644 T Phosphorylation PhosphoELM.10011 17081983 O75150 114 S Phosphorylation Phosphositeplus.1010730 21362549 O75150 819 S Phosphorylation Phosphositeplus.1010730 17478428 O75150 853 S Phosphorylation Phosphositeplus.1010730 17478428 O75150 127 T Phosphorylation Phosphositeplus.1010730 18077418 O75150 644 T Phosphorylation Phosphositeplus.1010730 17081983;20068231 O75150 20 K Acetylation HPRD 9.0 19608861 O75150 127 T Phosphorylation HPRD 9.0 18077418 O75150 644 T Phosphorylation HPRD 9.0 17081983,20068231 O75150 644 T Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References RNF40 127 T Phosphorylation 18077418 RNF40 20 K Acetylation 19608861 RNF40 644 T Phosphorylation 17081983,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O75150 644 T 17081983 HTP Phosphorylation

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type RNF40 IPI00162563 K 20 GSGPPEaKKLSREE acetylation RNF40 IPI00162563 T 644 KAKVEEpTKRKESE phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 9810 115149 - K Ubiquitination 21139048 9810 115149 - K Sumoylation 19471022 9810 115149 - K Ubiquitination 21890473 9810 115149 - K Ubiquitination 23000965 9810 115149 - K Ubiquitination 24816145 9810 115149 - K Sumoylation 25391492

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID RNF40 Homo sapiens (Human) 688 "688,KDDANFKLMSERI" 688:21890473 RNF40 Homo sapiens (Human) 120 "120,KDDANFKLMSERI" 120:21890473 RNF40 Homo sapiens (Human) 688 "688,KDDANFKLMSERI" 688:21890473 RNF40 Homo sapiens (Human) 788 "788,KDDANFKLMSERI" 788:21890473 RNF40 Homo sapiens (Human) 688 "688,KDDANFKLMSERI" 688:21890473 RNF40 Homo sapiens (Human) 788 "788,KDDANFKLMSERI" 788:21890473 RNF40 Homo sapiens (Human) 788 "788,KDDANFKLMSERI" 788:21890473 RNF40 Homo sapiens (Human) 688 "688,KDDANFKLMSERI" 688:21890473 RNF40 Homo sapiens (Human) 788 "788,KDDANFKLMSERI" 788:21890473