Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 15 41195414 41195415 + Frame_Shift_Ins INS - - AG TCGA-PK-A5HB-01A-11D-A29I-10 TCGA-PK-A5HB-11A-11D-A29L-10 g.chr15:41195414_41195415insAG c.2797_2798insAG c.(2797-2799)aagfs p.K933fs BLCA 15 41192561 41192561 + Silent SNP C C G TCGA-E5-A4TZ-01A-11D-A31L-08 TCGA-E5-A4TZ-10B-01D-A31J-08 g.chr15:41192561C>G c.1545C>G c.(1543-1545)ctC>ctG p.L515L BLCA 15 41192994 41192994 + Missense_Mutation SNP G G A TCGA-BT-A3PH-01A-11D-A21Z-08 TCGA-BT-A3PH-10A-01D-A21Z-08 g.chr15:41192994G>A c.1978G>A c.(1978-1980)Gag>Aag p.E660K BLCA 15 41194990 41194990 + Missense_Mutation SNP C C G TCGA-E5-A4TZ-01A-11D-A31L-08 TCGA-E5-A4TZ-10B-01D-A31J-08 g.chr15:41194990C>G c.2373C>G c.(2371-2373)ttC>ttG p.F791L BLCA 15 41195241 41195241 + Missense_Mutation SNP A A G TCGA-DK-AA6U-01A-11D-A391-08 TCGA-DK-AA6U-10A-01D-A394-08 g.chr15:41195241A>G c.2624A>G c.(2623-2625)cAt>cGt p.H875R BRCA 15 41192326 41192326 + Missense_Mutation SNP G G A TCGA-BH-A0AY-01A-21W-A019-09 TCGA-BH-A0AY-10A-01W-A021-09 g.chr15:41192326G>A c.1310G>A c.(1309-1311)cGt>cAt p.R437H BRCA 15 41193091 41193091 + Frame_Shift_Del DEL G G - TCGA-E2-A1LS-01A-12D-A159-09 TCGA-E2-A1LS-11A-32W-A16L-09 g.chr15:41193091delG c.2075delG c.(2074-2076)cggfs p.R692fs BRCA 15 41194898 41194898 + Missense_Mutation SNP C C G TCGA-E2-A14S-01A-11D-A12B-09 TCGA-E2-A14S-10A-01D-A12B-09 g.chr15:41194898C>G c.2281C>G c.(2281-2283)Cgg>Ggg p.R761G BRCA 15 41195138 41195138 + Missense_Mutation SNP C C T TCGA-AR-A0TU-01A-31D-A10G-09 TCGA-AR-A0TU-10A-01D-A10G-09 g.chr15:41195138C>T c.2521C>T c.(2521-2523)Cgg>Tgg p.R841W CESC 15 41191573 41191573 + Missense_Mutation SNP C C T TCGA-C5-A3HE-01A-21D-A22X-09 TCGA-C5-A3HE-10A-01D-A22X-09 g.chr15:41191573C>T c.557C>T c.(556-558)cCg>cTg p.P186L CESC 15 41192812 41192812 + Missense_Mutation SNP C C T TCGA-JX-A3Q0-01A-11D-A21Q-09 TCGA-JX-A3Q0-10A-01D-A21Q-09 g.chr15:41192812C>T c.1796C>T c.(1795-1797)tCa>tTa p.S599L COAD 15 41191372 41191372 + Missense_Mutation SNP C C T TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:41191372C>T c.356C>T c.(355-357)aCg>aTg p.T119M COAD 15 41191388 41191388 + Silent SNP G G T TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr15:41191388G>T c.372G>T c.(370-372)gtG>gtT p.V124V COAD 15 41191534 41191534 + Missense_Mutation SNP A A G TCGA-AD-6888-01A-11D-1924-10 TCGA-AD-6888-10A-01D-1924-10 g.chr15:41191534A>G c.518A>G c.(517-519)gAg>gGg p.E173G COAD 15 41192393 41192393 + Missense_Mutation SNP G G T TCGA-AA-A02F-01A-01W-A00E-09 TCGA-AA-A02F-10A-01W-A00E-09 g.chr15:41192393G>T c.1377G>T c.(1375-1377)aaG>aaT p.K459N COAD 15 41192668 41192668 + Missense_Mutation SNP G G A TCGA-G4-6304-01A-11D-1924-10 TCGA-G4-6304-10A-01D-1924-10 g.chr15:41192668G>A c.1652G>A c.(1651-1653)gGg>gAg p.G551E COAD 15 41195112 41195112 + Missense_Mutation SNP G G A TCGA-AA-3864-01A-01W-0995-10 TCGA-AA-3864-10A-01W-0995-10 g.chr15:41195112G>A c.2495G>A c.(2494-2496)cGc>cAc p.R832H COAD 15 41195209 41195209 + Silent SNP T T C TCGA-AY-6197-01A-11D-1719-10 TCGA-AY-6197-10A-01D-1719-10 g.chr15:41195209T>C c.2592T>C c.(2590-2592)ccT>ccC p.P864P COADREAD 15 41191372 41191372 + Missense_Mutation SNP C C T TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr15:41191372C>T c.356C>T c.(355-357)aCg>aTg p.T119M COADREAD 15 41191388 41191388 + Silent SNP G G T TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr15:41191388G>T c.372G>T c.(370-372)gtG>gtT p.V124V COADREAD 15 41191534 41191534 + Missense_Mutation SNP A A G TCGA-AD-6888-01A-11D-1924-10 TCGA-AD-6888-10A-01D-1924-10 g.chr15:41191534A>G c.518A>G c.(517-519)gAg>gGg p.E173G COADREAD 15 41192393 41192393 + Missense_Mutation SNP G G T TCGA-AA-A02F-01A-01W-A00E-09 TCGA-AA-A02F-10A-01W-A00E-09 g.chr15:41192393G>T c.1377G>T c.(1375-1377)aaG>aaT p.K459N COADREAD 15 41192668 41192668 + Missense_Mutation SNP G G A TCGA-G4-6304-01A-11D-1924-10 TCGA-G4-6304-10A-01D-1924-10 g.chr15:41192668G>A c.1652G>A c.(1651-1653)gGg>gAg p.G551E COADREAD 15 41195112 41195112 + Missense_Mutation SNP G G A TCGA-AA-3864-01A-01W-0995-10 TCGA-AA-3864-10A-01W-0995-10 g.chr15:41195112G>A c.2495G>A c.(2494-2496)cGc>cAc p.R832H COADREAD 15 41195209 41195209 + Silent SNP T T C TCGA-AY-6197-01A-11D-1719-10 TCGA-AY-6197-10A-01D-1719-10 g.chr15:41195209T>C c.2592T>C c.(2590-2592)ccT>ccC p.P864P DLBC 15 41191184 41191184 + Missense_Mutation SNP C C T TCGA-G8-6909-01A-11D-2210-10 TCGA-G8-6909-14A-01D-2210-10 g.chr15:41191184C>T c.313C>T c.(313-315)Ctt>Ttt p.L105F DLBC 15 41192540 41192540 + Silent SNP C C T TCGA-G8-6914-01A-11D-2210-10 TCGA-G8-6914-14A-01D-2210-10 g.chr15:41192540C>T c.1524C>T c.(1522-1524)ggC>ggT p.G508G ESCA 15 41192273 41192273 + Silent SNP C C T TCGA-LN-A49V-01A-11D-A247-09 TCGA-LN-A49V-10A-01D-A247-09 g.chr15:41192273C>T c.1257C>T c.(1255-1257)ccC>ccT p.P419P ESCA 15 41192668 41192668 + Missense_Mutation SNP G G T TCGA-R6-A6Y0-01B-11D-A33E-09 TCGA-R6-A6Y0-10A-01D-A33H-09 g.chr15:41192668G>T c.1652G>T c.(1651-1653)gGg>gTg p.G551V ESCA 15 41195002 41195002 + Silent SNP C C T TCGA-R6-A8W8-01B-11D-A37C-09 TCGA-R6-A8W8-10A-01D-A37F-09 g.chr15:41195002C>T c.2385C>T c.(2383-2385)ttC>ttT p.F795F ESCA 15 41195145 41195145 + Missense_Mutation SNP G G A TCGA-2H-A9GF-01A-11D-A37C-09 TCGA-2H-A9GF-11A-11D-A37F-09 g.chr15:41195145G>A c.2528G>A c.(2527-2529)cGc>cAc p.R843H ESCA 15 41195198 41195198 + Missense_Mutation SNP C C A TCGA-L5-A8NI-01A-11D-A37C-09 TCGA-L5-A8NI-11A-11D-A37F-09 g.chr15:41195198C>A c.2581C>A c.(2581-2583)Ctc>Atc p.L861I GBM 15 41191139 41191139 + Missense_Mutation SNP G G A TCGA-28-5215-01A-01D-1486-08 TCGA-28-5215-10A-01D-1486-08 g.chr15:41191139G>A c.268G>A c.(268-270)Gtg>Atg p.V90M GBM 15 41191638 41191638 + Missense_Mutation SNP C C T TCGA-06-6390-01A-11D-1696-08 TCGA-06-6390-10A-01D-1696-08 g.chr15:41191638C>T c.622C>T c.(622-624)Ctt>Ttt p.L208F GBM 15 41193044 41193044 + Silent SNP G G A TCGA-76-6282-01A-11D-1696-08 TCGA-76-6282-10A-01D-1696-08 g.chr15:41193044G>A c.2028G>A c.(2026-2028)ccG>ccA p.P676P GBMLGG 15 41191139 41191139 + Missense_Mutation SNP G G A TCGA-28-5215-01A-01D-1486-08 TCGA-28-5215-10A-01D-1486-08 g.chr15:41191139G>A c.268G>A c.(268-270)Gtg>Atg p.V90M GBMLGG 15 41191638 41191638 + Missense_Mutation SNP C C T TCGA-06-6390-01A-11D-1696-08 TCGA-06-6390-10A-01D-1696-08 g.chr15:41191638C>T c.622C>T c.(622-624)Ctt>Ttt p.L208F GBMLGG 15 41191832 41191832 + Missense_Mutation SNP C C G TCGA-DH-A7UV-01A-12D-A34A-08 TCGA-DH-A7UV-10A-01D-A34A-08 g.chr15:41191832C>G c.816C>G c.(814-816)ttC>ttG p.F272L GBMLGG 15 41191890 41191890 + Missense_Mutation SNP G G T TCGA-RY-A843-01A-11D-A36O-08 TCGA-RY-A843-10A-01D-A367-08 g.chr15:41191890G>T c.874G>T c.(874-876)Gtg>Ttg p.V292L GBMLGG 15 41192203 41192203 + Missense_Mutation SNP G G T TCGA-HT-7473-01A-11D-2024-08 TCGA-HT-7473-10A-01D-2024-08 g.chr15:41192203G>T c.1187G>T c.(1186-1188)cGa>cTa p.R396L GBMLGG 15 41192696 41192696 + Silent SNP A A G TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr15:41192696A>G c.1680A>G c.(1678-1680)gcA>gcG p.A560A GBMLGG 15 41193044 41193044 + Silent SNP G G A TCGA-76-6282-01A-11D-1696-08 TCGA-76-6282-10A-01D-1696-08 g.chr15:41193044G>A c.2028G>A c.(2026-2028)ccG>ccA p.P676P GBMLGG 15 41193044 41193044 + Silent SNP G G A TCGA-DU-8166-01A-11D-2253-08 TCGA-DU-8166-10A-01D-2253-08 g.chr15:41193044G>A c.2028G>A c.(2026-2028)ccG>ccA p.P676P GBMLGG 15 41193149 41193149 + Silent SNP C C T TCGA-HT-A619-01A-11D-A29Q-08 TCGA-HT-A619-10A-01D-A29Q-08 g.chr15:41193149C>T c.2133C>T c.(2131-2133)cgC>cgT p.R711R HNSC 15 41191580 41191580 + Silent SNP C C G TCGA-CR-6482-01A-11D-1870-08 TCGA-CR-6482-10A-01D-1870-08 g.chr15:41191580C>G c.564C>G c.(562-564)ctC>ctG p.L188L HNSC 15 41191637 41191637 + Silent SNP C C T TCGA-D6-6516-01A-11D-1870-08 TCGA-D6-6516-10A-01D-1870-08 g.chr15:41191637C>T c.621C>T c.(619-621)tcC>tcT p.S207S HNSC 15 41191868 41191868 + Silent SNP C C T TCGA-QK-A8Z7-01A-11D-A391-08 TCGA-QK-A8Z7-10A-01D-A394-08 g.chr15:41191868C>T c.852C>T c.(850-852)ttC>ttT p.F284F HNSC 15 41193186 41193186 + Missense_Mutation SNP G G A TCGA-BB-A5HU-01A-11D-A28R-08 TCGA-BB-A5HU-10A-01D-A28U-08 g.chr15:41193186G>A c.2170G>A c.(2170-2172)Gag>Aag p.E724K HNSC 15 41195445 41195445 + Missense_Mutation SNP A A T TCGA-F7-A624-01A-22D-A30E-08 TCGA-F7-A624-10A-01D-A30H-08 g.chr15:41195445A>T c.2828A>T c.(2827-2829)gAg>gTg p.E943V KICH 15 41191887 41191887 + Missense_Mutation SNP G G T TCGA-KM-8639-01A-11D-2397-10 TCGA-KM-8639-10A-01D-2397-10 g.chr15:41191887G>T c.871G>T c.(871-873)Ggt>Tgt p.G291C KIPAN 15 41188258 41188258 + Missense_Mutation SNP G G C TCGA-CJ-4634-01A-02D-1386-10 TCGA-CJ-4634-11A-01D-1251-10 g.chr15:41188258G>C c.214G>C c.(214-216)Ggc>Cgc p.G72R KIPAN 15 41191884 41191884 + Missense_Mutation SNP G G A TCGA-B9-A8YI-01A-21D-A36X-10 TCGA-B9-A8YI-10A-01D-A370-10 g.chr15:41191884G>A c.868G>A c.(868-870)Gat>Aat p.D290N KIPAN 15 41191887 41191887 + Missense_Mutation SNP G G T TCGA-KM-8639-01A-11D-2397-10 TCGA-KM-8639-10A-01D-2397-10 g.chr15:41191887G>T c.871G>T c.(871-873)Ggt>Tgt p.G291C KIPAN 15 41191988 41191988 + Silent SNP A A C TCGA-B0-5693-01A-11D-1534-10 TCGA-B0-5693-11A-01D-1534-10 g.chr15:41191988A>C c.972A>C c.(970-972)ccA>ccC p.P324P KIPAN 15 41192166 41192166 + Missense_Mutation SNP C C T TCGA-B0-4852-01A-01D-1501-10 TCGA-B0-4852-11A-01D-1501-10 g.chr15:41192166C>T c.1150C>T c.(1150-1152)Cgg>Tgg p.R384W KIPAN 15 41192359 41192359 + Missense_Mutation SNP T T C TCGA-B0-5098-01A-01D-1421-08 TCGA-B0-5098-11A-01D-1421-08 g.chr15:41192359T>C c.1343T>C c.(1342-1344)cTg>cCg p.L448P KIPAN 15 41194909 41194909 + Silent SNP G G T TCGA-B0-5094-01A-01D-1421-08 TCGA-B0-5094-11A-01D-1421-08 g.chr15:41194909G>T c.2292G>T c.(2290-2292)gtG>gtT p.V764V KIRC 15 41188258 41188258 + Missense_Mutation SNP G G C TCGA-CJ-4634-01A-02D-1386-10 TCGA-CJ-4634-11A-01D-1251-10 g.chr15:41188258G>C c.214G>C c.(214-216)Ggc>Cgc p.G72R KIRC 15 41191988 41191988 + Silent SNP A A C TCGA-B0-5693-01A-11D-1534-10 TCGA-B0-5693-11A-01D-1534-10 g.chr15:41191988A>C c.972A>C c.(970-972)ccA>ccC p.P324P KIRC 15 41192166 41192166 + Missense_Mutation SNP C C T TCGA-B0-4852-01A-01D-1501-10 TCGA-B0-4852-11A-01D-1501-10 g.chr15:41192166C>T c.1150C>T c.(1150-1152)Cgg>Tgg p.R384W KIRC 15 41192359 41192359 + Missense_Mutation SNP T T C TCGA-B0-5098-01A-01D-1421-08 TCGA-B0-5098-11A-01D-1421-08 g.chr15:41192359T>C c.1343T>C c.(1342-1344)cTg>cCg p.L448P KIRC 15 41194909 41194909 + Silent SNP G G T TCGA-B0-5094-01A-01D-1421-08 TCGA-B0-5094-11A-01D-1421-08 g.chr15:41194909G>T c.2292G>T c.(2290-2292)gtG>gtT p.V764V KIRP 15 41191884 41191884 + Missense_Mutation SNP G G A TCGA-B9-A8YI-01A-21D-A36X-10 TCGA-B9-A8YI-10A-01D-A370-10 g.chr15:41191884G>A c.868G>A c.(868-870)Gat>Aat p.D290N LGG 15 41191832 41191832 + Missense_Mutation SNP C C G TCGA-DH-A7UV-01A-12D-A34A-08 TCGA-DH-A7UV-10A-01D-A34A-08 g.chr15:41191832C>G c.816C>G c.(814-816)ttC>ttG p.F272L LGG 15 41191890 41191890 + Missense_Mutation SNP G G T TCGA-RY-A843-01A-11D-A36O-08 TCGA-RY-A843-10A-01D-A367-08 g.chr15:41191890G>T c.874G>T c.(874-876)Gtg>Ttg p.V292L LGG 15 41192203 41192203 + Missense_Mutation SNP G G T TCGA-HT-7473-01A-11D-2024-08 TCGA-HT-7473-10A-01D-2024-08 g.chr15:41192203G>T c.1187G>T c.(1186-1188)cGa>cTa p.R396L LGG 15 41192696 41192696 + Silent SNP A A G TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr15:41192696A>G c.1680A>G c.(1678-1680)gcA>gcG p.A560A LGG 15 41193044 41193044 + Silent SNP G G A TCGA-DU-8166-01A-11D-2253-08 TCGA-DU-8166-10A-01D-2253-08 g.chr15:41193044G>A c.2028G>A c.(2026-2028)ccG>ccA p.P676P LGG 15 41193149 41193149 + Silent SNP C C T TCGA-HT-A619-01A-11D-A29Q-08 TCGA-HT-A619-10A-01D-A29Q-08 g.chr15:41193149C>T c.2133C>T c.(2131-2133)cgC>cgT p.R711R LIHC 15 41187016 41187016 + Missense_Mutation SNP T T C TCGA-EP-A2KA-01A-11D-A183-10 TCGA-EP-A2KA-10A-01D-A183-10 g.chr15:41187016T>C c.50T>C c.(49-51)gTc>gCc p.V17A LIHC 15 41191112 41191112 + Silent SNP T T C TCGA-ES-A2HT-01A-12D-A183-10 TCGA-ES-A2HT-11A-11D-A183-10 g.chr15:41191112T>C c.241T>C c.(241-243)Ttg>Ctg p.L81L LIHC 15 41191757 41191757 + Silent SNP C C T TCGA-DD-AADN-01A-11D-A40R-10 TCGA-DD-AADN-10A-01D-A40U-10 g.chr15:41191757C>T c.741C>T c.(739-741)ctC>ctT p.L247L LUAD 15 41188135 41188135 + Splice_Site SNP G G T TCGA-17-Z055-01A-01W-0747-08 TCGA-17-Z055-11A-01W-0747-08 g.chr15:41188135G>T c.e2-1 LUAD 15 41188205 41188205 + Missense_Mutation SNP C C T TCGA-17-Z003-01A-01W-0746-08 TCGA-17-Z003-11A-01W-0746-08 g.chr15:41188205C>T c.161C>T c.(160-162)tCc>tTc p.S54F LUAD 15 41188228 41188228 + Missense_Mutation SNP G G A TCGA-86-8076-01A-31D-2238-08 TCGA-86-8076-10A-01D-2238-08 g.chr15:41188228G>A c.184G>A c.(184-186)Gtc>Atc p.V62I LUAD 15 41191514 41191514 + Missense_Mutation SNP A A T TCGA-97-8174-01A-11D-2284-08 TCGA-97-8174-10A-01D-2284-08 g.chr15:41191514A>T c.498A>T c.(496-498)caA>caT p.Q166H LUAD 15 41192007 41192007 + Missense_Mutation SNP A A T TCGA-78-8662-01A-11D-2393-08 TCGA-78-8662-10A-01D-2393-08 g.chr15:41192007A>T c.991A>T c.(991-993)Acc>Tcc p.T331S LUAD 15 41192082 41192083 + Frame_Shift_Ins INS - - G TCGA-99-8025-01A-11D-2238-08 TCGA-99-8025-10A-01D-2238-08 g.chr15:41192082_41192083insG c.1066_1067insG c.(1066-1068)cggfs p.R356fs LUAD 15 41192839 41192839 + Missense_Mutation SNP G G T TCGA-44-7670-01A-11D-2063-08 TCGA-44-7670-10A-01D-2063-08 g.chr15:41192839G>T c.1823G>T c.(1822-1824)cGc>cTc p.R608L LUAD 15 41193186 41193186 + Nonsense_Mutation SNP G G T TCGA-97-8174-01A-11D-2284-08 TCGA-97-8174-10A-01D-2284-08 g.chr15:41193186G>T c.2170G>T c.(2170-2172)Gag>Tag p.E724* LUAD 15 41194859 41194859 + Missense_Mutation SNP G G T TCGA-05-4422-01A-01D-1265-08 TCGA-05-4422-10A-01D-1265-08 g.chr15:41194859G>T c.2242G>T c.(2242-2244)Gat>Tat p.D748Y LUSC 15 41192320 41192320 + Missense_Mutation SNP G G T TCGA-33-4583-01A-01D-1441-08 TCGA-33-4583-11A-01D-1441-08 g.chr15:41192320G>T c.1304G>T c.(1303-1305)cGc>cTc p.R435L LUSC 15 41192573 41192573 + Silent SNP C C G TCGA-66-2793-01A-01D-1267-08 TCGA-66-2793-11A-01D-1267-08 g.chr15:41192573C>G c.1557C>G c.(1555-1557)acC>acG p.T519T OV 15 41191655 41191655 + Silent SNP C C T TCGA-61-2101-01A-01W-0722-08 TCGA-61-2101-11A-01W-0723-08 g.chr15:41191655C>T c.639C>T c.(637-639)ggC>ggT p.G213G OV 15 41193072 41193072 + Missense_Mutation SNP G G A TCGA-23-1118-01A-01W-0488-09 TCGA-23-1118-10A-01W-0488-09 g.chr15:41193072G>A c.2056G>A c.(2056-2058)Gct>Act p.A686T PAAD 15 41192523 41192523 + Missense_Mutation SNP C C A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr15:41192523C>A c.1507C>A c.(1507-1509)Ctt>Att p.L503I PAAD 15 41192857 41192857 + Nonsense_Mutation SNP G G A TCGA-OE-A75W-01A-12D-A32N-08 TCGA-OE-A75W-10A-01D-A32N-08 g.chr15:41192857G>A c.1841G>A c.(1840-1842)tGg>tAg p.W614* PAAD 15 41194882 41194882 + Silent SNP G G A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr15:41194882G>A c.2265G>A c.(2263-2265)ctG>ctA p.L755L PRAD 15 41192034 41192034 + Missense_Mutation SNP G G A TCGA-ZG-A9LU-01A-11D-A41K-08 TCGA-ZG-A9LU-10A-01D-A41N-08 g.chr15:41192034G>A c.1018G>A c.(1018-1020)Gca>Aca p.A340T PRAD 15 41192240 41192240 + Silent SNP C C T TCGA-KK-A5A1-01A-11D-A29Q-08 TCGA-KK-A5A1-11A-12D-A29Q-08 g.chr15:41192240C>T c.1224C>T c.(1222-1224)ttC>ttT p.F408F SARC 15 41191385 41191385 + Silent SNP C C T TCGA-DX-AB32-01A-11D-A417-09 TCGA-DX-AB32-10A-01D-A41A-09 g.chr15:41191385C>T c.369C>T c.(367-369)taC>taT p.Y123Y SKCM 15 41188156 41188156 + Missense_Mutation SNP G G A TCGA-FW-A3TU-06A-11D-A23B-08 TCGA-FW-A3TU-10A-01D-A23B-08 g.chr15:41188156G>A c.112G>A c.(112-114)Gag>Aag p.E38K SKCM 15 41188270 41188270 + Silent SNP C C T TCGA-ER-A19D-06A-11D-A197-08 TCGA-ER-A19D-10A-01D-A199-08 g.chr15:41188270C>T c.226C>T c.(226-228)Ctg>Ttg p.L76L SKCM 15 41191361 41191361 + Silent SNP C C T TCGA-DA-A1HV-06A-21D-A196-08 TCGA-DA-A1HV-10A-01D-A198-08 g.chr15:41191361C>T c.345C>T c.(343-345)gcC>gcT p.A115A SKCM 15 41191637 41191637 + Silent SNP C C T TCGA-EE-A181-06A-11D-A196-08 TCGA-EE-A181-10A-01D-A198-08 g.chr15:41191637C>T c.621C>T c.(619-621)tcC>tcT p.S207S SKCM 15 41191790 41191790 + Silent SNP C C T TCGA-ER-A193-06A-12D-A197-08 TCGA-ER-A193-10A-01D-A199-08 g.chr15:41191790C>T c.774C>T c.(772-774)ttC>ttT p.F258F SKCM 15 41192210 41192210 + Silent SNP C C T TCGA-EE-A29V-06A-12D-A197-08 TCGA-EE-A29V-10A-01D-A199-08 g.chr15:41192210C>T c.1194C>T c.(1192-1194)gtC>gtT p.V398V SKCM 15 41192240 41192240 + Silent SNP C C T TCGA-FS-A1ZZ-06A-11D-A197-08 TCGA-FS-A1ZZ-10A-01D-A199-08 g.chr15:41192240C>T c.1224C>T c.(1222-1224)ttC>ttT p.F408F SKCM 15 41192313 41192313 + Missense_Mutation SNP T T C TCGA-QB-A6FS-06A-11D-A30X-08 TCGA-QB-A6FS-10A-01D-A30X-08 g.chr15:41192313T>C c.1297T>C c.(1297-1299)Tgc>Cgc p.C433R SKCM 15 41192378 41192378 + Silent SNP G G A TCGA-DA-A1I5-06A-11D-A197-08 TCGA-DA-A1I5-10A-01D-A199-08 g.chr15:41192378G>A c.1362G>A c.(1360-1362)gaG>gaA p.E454E SKCM 15 41192646 41192646 + Missense_Mutation SNP C C T TCGA-EE-A2MR-06A-11D-A196-08 TCGA-EE-A2MR-10A-01D-A198-08 g.chr15:41192646C>T c.1630C>T c.(1630-1632)Cat>Tat p.H544Y SKCM 15 41192876 41192876 + Silent SNP G G A TCGA-GN-A4U8-06A-11D-A32N-08 TCGA-GN-A4U8-10B-01D-A32N-08 g.chr15:41192876G>A c.1860G>A c.(1858-1860)cgG>cgA p.R620R SKCM 15 41194915 41194915 + Missense_Mutation SNP A A T TCGA-ER-A193-06A-12D-A197-08 TCGA-ER-A193-10A-01D-A199-08 g.chr15:41194915A>T c.2298A>T c.(2296-2298)gaA>gaT p.E766D SKCM 15 41195020 41195020 + Silent SNP C C T TCGA-EE-A2A2-06A-11D-A196-08 TCGA-EE-A2A2-10A-01D-A198-08 g.chr15:41195020C>T c.2403C>T c.(2401-2403)ttC>ttT p.F801F

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 15 41193012 41193012 single base substitution T C downstream_gene_variant BLCA-CN 15 41193012 41193012 single base substitution T C intron_variant BLCA-CN 15 41193012 41193012 single base substitution T C missense_variant Y666H 1996T>C BLCA-US 15 41192994 41192994 single base substitution G A downstream_gene_variant BLCA-US 15 41192994 41192994 single base substitution G A intron_variant BLCA-US 15 41192994 41192994 single base substitution G A missense_variant E660K 1978G>A BOCA-FR 15 41192076 41192076 single base substitution G C downstream_gene_variant BOCA-FR 15 41192076 41192076 single base substitution G C intron_variant BOCA-FR 15 41192076 41192076 single base substitution G C missense_variant V354L 1060G>C BRCA-EU 15 41181679 41181679 single base substitution C T upstream_gene_variant BRCA-EU 15 41182389 41182389 single base substitution C A upstream_gene_variant BRCA-EU 15 41184067 41184067 single base substitution C T upstream_gene_variant BRCA-EU 15 41184111 41184111 single base substitution T C upstream_gene_variant BRCA-EU 15 41184353 41184353 single base substitution C T upstream_gene_variant BRCA-EU 15 41184456 41184456 single base substitution C G upstream_gene_variant BRCA-EU 15 41185022 41185022 single base substitution C G upstream_gene_variant BRCA-EU 15 41185679 41185679 single base substitution C G upstream_gene_variant BRCA-EU 15 41186117 41186117 single base substitution C A upstream_gene_variant BRCA-EU 15 41188065 41188065 insertion of <=200bp - T intron_variant BRCA-EU 15 41188713 41188713 single base substitution T A intron_variant BRCA-EU 15 41189159 41189159 single base substitution A G intron_variant BRCA-EU 15 41189564 41189564 single base substitution C T intron_variant BRCA-EU 15 41192102 41192102 single base substitution A C downstream_gene_variant BRCA-EU 15 41192102 41192102 single base substitution A C intron_variant BRCA-EU 15 41192102 41192102 single base substitution A C missense_variant K362N 1086A>C BRCA-EU 15 41192729 41192729 single base substitution T G downstream_gene_variant BRCA-EU 15 41192729 41192729 single base substitution T G intron_variant BRCA-EU 15 41192729 41192729 single base substitution T G synonymous_variant A571A 1713T>G BRCA-EU 15 41193362 41193362 single base substitution G A downstream_gene_variant BRCA-EU 15 41193362 41193362 single base substitution G A intron_variant BRCA-EU 15 41194887 41194887 single base substitution T A 3_prime_UTR_variant BRCA-EU 15 41194887 41194887 single base substitution T A downstream_gene_variant BRCA-EU 15 41194887 41194887 single base substitution T A missense_variant L757Q 2270T>A BRCA-EU 15 41196072 41196072 single base substitution C T 3_prime_UTR_variant BRCA-EU 15 41196072 41196072 single base substitution C T downstream_gene_variant BRCA-EU 15 41198888 41198888 single base substitution G A downstream_gene_variant BRCA-EU 15 41199997 41199997 single base substitution C A downstream_gene_variant BRCA-EU 15 41200020 41200020 single base substitution A T downstream_gene_variant BRCA-FR 15 41186225 41186225 single base substitution G A upstream_gene_variant BRCA-FR 15 41194887 41194887 single base substitution T A 3_prime_UTR_variant BRCA-FR 15 41194887 41194887 single base substitution T A downstream_gene_variant BRCA-FR 15 41194887 41194887 single base substitution T A missense_variant L757Q 2270T>A BRCA-FR 15 41195861 41195861 single base substitution A T 3_prime_UTR_variant BRCA-FR 15 41195861 41195861 single base substitution A T downstream_gene_variant BRCA-US 15 41192326 41192326 single base substitution G A downstream_gene_variant BRCA-US 15 41192326 41192326 single base substitution G A intron_variant BRCA-US 15 41192326 41192326 single base substitution G A missense_variant R437H 1310G>A BRCA-US 15 41193091 41193091 deletion of <=200bp G - downstream_gene_variant BRCA-US 15 41193091 41193091 deletion of <=200bp G - frameshift_variant R692 BRCA-US 15 41193091 41193091 deletion of <=200bp G - intron_variant BRCA-US 15 41194898 41194898 single base substitution C G 3_prime_UTR_variant BRCA-US 15 41194898 41194898 single base substitution C G downstream_gene_variant BRCA-US 15 41194898 41194898 single base substitution C G missense_variant R761G 2281C>G BRCA-US 15 41195138 41195138 single base substitution C T downstream_gene_variant BRCA-US 15 41195138 41195138 single base substitution C T missense_variant R841W 2521C>T BTCA-JP 15 41191651 41191651 single base substitution G A downstream_gene_variant BTCA-JP 15 41191651 41191651 single base substitution G A intron_variant BTCA-JP 15 41191651 41191651 single base substitution G A missense_variant R212Q 635G>A CESC-US 15 41191573 41191573 single base substitution C T 3_prime_UTR_variant CESC-US 15 41191573 41191573 single base substitution C T intron_variant CESC-US 15 41191573 41191573 single base substitution C T missense_variant P186L 557C>T CESC-US 15 41192812 41192812 single base substitution C T downstream_gene_variant CESC-US 15 41192812 41192812 single base substitution C T intron_variant CESC-US 15 41192812 41192812 single base substitution C T missense_variant S599L 1796C>T COAD-US 15 41191372 41191372 single base substitution C T 3_prime_UTR_variant COAD-US 15 41191372 41191372 single base substitution C T intron_variant COAD-US 15 41191372 41191372 single base substitution C T missense_variant T119M 356C>T COAD-US 15 41192325 41192325 single base substitution C T downstream_gene_variant COAD-US 15 41192325 41192325 single base substitution C T intron_variant COAD-US 15 41192325 41192325 single base substitution C T missense_variant R437C 1309C>T COAD-US 15 41195209 41195209 single base substitution T C downstream_gene_variant COAD-US 15 41195209 41195209 single base substitution T C synonymous_variant P864P 2592T>C COCA-CN 15 41191296 41191296 single base substitution T C intron_variant COCA-CN 15 41192143 41192143 single base substitution G A downstream_gene_variant COCA-CN 15 41192143 41192143 single base substitution G A intron_variant COCA-CN 15 41192143 41192143 single base substitution G A missense_variant G376D 1127G>A COCA-CN 15 41192319 41192319 single base substitution C T downstream_gene_variant COCA-CN 15 41192319 41192319 single base substitution C T intron_variant COCA-CN 15 41192319 41192319 single base substitution C T missense_variant R435C 1303C>T COCA-CN 15 41193020 41193020 single base substitution G A downstream_gene_variant COCA-CN 15 41193020 41193020 single base substitution G A intron_variant COCA-CN 15 41193020 41193020 single base substitution G A synonymous_variant L668L 2004G>A COCA-CN 15 41193316 41193316 single base substitution C T downstream_gene_variant COCA-CN 15 41193316 41193316 single base substitution C T intron_variant COCA-CN 15 41194940 41194940 single base substitution G A 3_prime_UTR_variant COCA-CN 15 41194940 41194940 single base substitution G A downstream_gene_variant COCA-CN 15 41194940 41194940 single base substitution G A missense_variant A775T 2323G>A COCA-CN 15 41195121 41195121 single base substitution G A downstream_gene_variant COCA-CN 15 41195121 41195121 single base substitution G A missense_variant R835Q 2504G>A COCA-CN 15 41195441 41195441 single base substitution G A downstream_gene_variant COCA-CN 15 41195441 41195441 single base substitution G A missense_variant A942T 2824G>A ESAD-UK 15 41183401 41183401 single base substitution C T upstream_gene_variant ESAD-UK 15 41184598 41184628 deletion of <=200bp ACTGAAGCTAAGAGCATCAACTGTGCAGTGT - upstream_gene_variant ESAD-UK 15 41186178 41186178 single base substitution G A upstream_gene_variant ESAD-UK 15 41186306 41186306 single base substitution G A upstream_gene_variant ESAD-UK 15 41190366 41190366 single base substitution G A intron_variant ESAD-UK 15 41190441 41190441 single base substitution C T intron_variant ESAD-UK 15 41192454 41192454 single base substitution T C downstream_gene_variant ESAD-UK 15 41192454 41192454 single base substitution T C intron_variant ESAD-UK 15 41192454 41192454 single base substitution T C synonymous_variant L480L 1438T>C ESAD-UK 15 41194285 41194285 single base substitution A C downstream_gene_variant ESAD-UK 15 41194285 41194285 single base substitution A C intron_variant ESAD-UK 15 41197088 41197088 single base substitution T G downstream_gene_variant ESAD-UK 15 41197569 41197569 single base substitution A G downstream_gene_variant ESAD-UK 15 41198206 41198206 single base substitution T C downstream_gene_variant ESAD-UK 15 41199636 41199636 single base substitution G T downstream_gene_variant GBM-US 15 41191139 41191139 single base substitution G A 3_prime_UTR_variant GBM-US 15 41191139 41191139 single base substitution G A missense_variant V90M 268G>A GBM-US 15 41193044 41193044 single base substitution G A downstream_gene_variant GBM-US 15 41193044 41193044 single base substitution G A intron_variant GBM-US 15 41193044 41193044 single base substitution G A synonymous_variant P676P 2028G>A KIRC-US 15 41188258 41188258 single base substitution G C exon_variant KIRC-US 15 41188258 41188258 single base substitution G C missense_variant G72R 214G>C KIRC-US 15 41191988 41191988 single base substitution A C downstream_gene_variant KIRC-US 15 41191988 41191988 single base substitution A C intron_variant KIRC-US 15 41191988 41191988 single base substitution A C synonymous_variant P324P 972A>C KIRC-US 15 41192166 41192166 single base substitution C T downstream_gene_variant KIRC-US 15 41192166 41192166 single base substitution C T intron_variant KIRC-US 15 41192166 41192166 single base substitution C T missense_variant R384W 1150C>T KIRC-US 15 41194909 41194909 single base substitution G T 3_prime_UTR_variant KIRC-US 15 41194909 41194909 single base substitution G T downstream_gene_variant KIRC-US 15 41194909 41194909 single base substitution G T synonymous_variant V764V 2292G>T LAML-CN 15 41195413 41195413 single base substitution C A downstream_gene_variant LAML-CN 15 41195413 41195413 single base substitution C A synonymous_variant L932L 2796C>A LICA-CN 15 41188234 41188234 single base substitution A T exon_variant LICA-CN 15 41188234 41188234 single base substitution A T missense_variant S64C 190A>T LICA-FR 15 41190672 41190672 deletion of <=200bp T - intron_variant LINC-JP 15 41193416 41193416 single base substitution C T downstream_gene_variant LINC-JP 15 41193416 41193416 single base substitution C T intron_variant LINC-JP 15 41194899 41194899 single base substitution G T 3_prime_UTR_variant LINC-JP 15 41194899 41194899 single base substitution G T downstream_gene_variant LINC-JP 15 41194899 41194899 single base substitution G T missense_variant R761L 2282G>T LIRI-JP 15 41181710 41181710 single base substitution G A upstream_gene_variant LIRI-JP 15 41183127 41183127 single base substitution C G upstream_gene_variant LIRI-JP 15 41184881 41184881 single base substitution G A upstream_gene_variant LIRI-JP 15 41186841 41186841 single base substitution G T 5_prime_UTR_variant LIRI-JP 15 41188486 41188486 single base substitution C T intron_variant LIRI-JP 15 41190194 41190194 single base substitution T G intron_variant LIRI-JP 15 41192425 41192425 single base substitution C T downstream_gene_variant LIRI-JP 15 41192425 41192425 single base substitution C T intron_variant LIRI-JP 15 41192425 41192425 single base substitution C T missense_variant A470V 1409C>T LIRI-JP 15 41196362 41196362 single base substitution G A downstream_gene_variant LIRI-JP 15 41197520 41197520 single base substitution C A downstream_gene_variant LIRI-JP 15 41197835 41197835 single base substitution T G downstream_gene_variant LUSC-KR 15 41186990 41186990 single base substitution C T exon_variant LUSC-KR 15 41186990 41186990 single base substitution C T synonymous_variant Y8Y 24C>T LUSC-KR 15 41188287 41188287 single base substitution A G intron_variant LUSC-KR 15 41189600 41189600 single base substitution T G intron_variant LUSC-KR 15 41192558 41192558 single base substitution T C downstream_gene_variant LUSC-KR 15 41192558 41192558 single base substitution T C intron_variant LUSC-KR 15 41192558 41192558 single base substitution T C synonymous_variant T514T 1542T>C LUSC-KR 15 41197152 41197152 single base substitution C G downstream_gene_variant LUSC-US 15 41192320 41192320 single base substitution G T downstream_gene_variant LUSC-US 15 41192320 41192320 single base substitution G T intron_variant LUSC-US 15 41192320 41192320 single base substitution G T missense_variant R435L 1304G>T LUSC-US 15 41192573 41192573 single base substitution C G downstream_gene_variant LUSC-US 15 41192573 41192573 single base substitution C G intron_variant LUSC-US 15 41192573 41192573 single base substitution C G synonymous_variant T519T 1557C>G MALY-DE 15 41185101 41185101 single base substitution G T upstream_gene_variant MALY-DE 15 41192110 41192110 single base substitution C T downstream_gene_variant MALY-DE 15 41192110 41192110 single base substitution C T intron_variant MALY-DE 15 41192110 41192110 single base substitution C T missense_variant P365L 1094C>T MALY-DE 15 41195879 41195880 deletion of <=200bp GA - 3_prime_UTR_variant MALY-DE 15 41195879 41195880 deletion of <=200bp GA - downstream_gene_variant MELA-AU 15 41182422 41182422 single base substitution G A upstream_gene_variant MELA-AU 15 41182554 41182554 single base substitution G A upstream_gene_variant MELA-AU 15 41182562 41182563 multiple base substitution (>=2bp and <=200bp) AT CA upstream_gene_variant MELA-AU 15 41182629 41182629 single base substitution G A upstream_gene_variant MELA-AU 15 41184253 41184253 single base substitution C T upstream_gene_variant MELA-AU 15 41184714 41184714 single base substitution C T upstream_gene_variant MELA-AU 15 41184882 41184882 single base substitution G A upstream_gene_variant MELA-AU 15 41184883 41184883 single base substitution G A upstream_gene_variant MELA-AU 15 41185047 41185047 single base substitution G A upstream_gene_variant MELA-AU 15 41185207 41185207 single base substitution C T upstream_gene_variant MELA-AU 15 41185270 41185270 single base substitution G A upstream_gene_variant MELA-AU 15 41185531 41185531 single base substitution G A upstream_gene_variant MELA-AU 15 41185998 41185998 single base substitution C T upstream_gene_variant MELA-AU 15 41186487 41186487 single base substitution G A upstream_gene_variant MELA-AU 15 41187959 41187959 single base substitution C T intron_variant MELA-AU 15 41188408 41188408 single base substitution C T intron_variant MELA-AU 15 41189093 41189093 single base substitution C T intron_variant MELA-AU 15 41190227 41190227 single base substitution C T intron_variant MELA-AU 15 41190465 41190465 single base substitution T C intron_variant MELA-AU 15 41190470 41190470 single base substitution C T intron_variant MELA-AU 15 41190640 41190640 single base substitution C T intron_variant MELA-AU 15 41190922 41190922 single base substitution C T exon_variant MELA-AU 15 41190922 41190922 single base substitution C T intron_variant MELA-AU 15 41191184 41191184 single base substitution C T 3_prime_UTR_variant MELA-AU 15 41191184 41191184 single base substitution C T missense_variant L105F 313C>T MELA-AU 15 41191645 41191645 single base substitution C T downstream_gene_variant MELA-AU 15 41191645 41191645 single base substitution C T intron_variant MELA-AU 15 41191645 41191645 single base substitution C T missense_variant A210V 629C>T MELA-AU 15 41193197 41193197 single base substitution G A downstream_gene_variant MELA-AU 15 41193197 41193197 single base substitution G A intron_variant MELA-AU 15 41193197 41193197 single base substitution G A synonymous_variant V727V 2181G>A MELA-AU 15 41195398 41195398 single base substitution C T downstream_gene_variant MELA-AU 15 41195398 41195398 single base substitution C T synonymous_variant P927P 2781C>T MELA-AU 15 41195878 41195878 single base substitution C T 3_prime_UTR_variant MELA-AU 15 41195878 41195878 single base substitution C T downstream_gene_variant MELA-AU 15 41195908 41195909 multiple base substitution (>=2bp and <=200bp) CC TT 3_prime_UTR_variant MELA-AU 15 41195908 41195909 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 15 41195971 41195971 single base substitution C T 3_prime_UTR_variant MELA-AU 15 41195971 41195971 single base substitution C T downstream_gene_variant MELA-AU 15 41196374 41196374 single base substitution C T downstream_gene_variant MELA-AU 15 41196379 41196379 single base substitution C T downstream_gene_variant MELA-AU 15 41196816 41196816 single base substitution C T downstream_gene_variant MELA-AU 15 41196851 41196851 single base substitution C T downstream_gene_variant MELA-AU 15 41197855 41197855 single base substitution G A downstream_gene_variant MELA-AU 15 41198940 41198940 single base substitution C T downstream_gene_variant MELA-AU 15 41199245 41199245 single base substitution C T downstream_gene_variant MELA-AU 15 41200102 41200102 single base substitution G A downstream_gene_variant MELA-AU 15 41200297 41200297 single base substitution C T downstream_gene_variant MELA-AU 15 41200789 41200789 single base substitution C G downstream_gene_variant MELA-AU 15 41201143 41201143 single base substitution C T downstream_gene_variant ORCA-IN 15 41191775 41191775 single base substitution C A downstream_gene_variant ORCA-IN 15 41191775 41191775 single base substitution C A intron_variant ORCA-IN 15 41191775 41191775 single base substitution C A missense_variant D253E 759C>A ORCA-IN 15 41197246 41197246 single base substitution C T downstream_gene_variant OV-AU 15 41195259 41195259 single base substitution A C downstream_gene_variant OV-AU 15 41195259 41195259 single base substitution A C missense_variant Q881P 2642A>C OV-US 15 41193072 41193072 single base substitution G A downstream_gene_variant OV-US 15 41193072 41193072 single base substitution G A intron_variant OV-US 15 41193072 41193072 single base substitution G A missense_variant A686T 2056G>A PACA-AU 15 41183554 41183554 single base substitution C G upstream_gene_variant PACA-AU 15 41189418 41189418 single base substitution G A intron_variant PACA-AU 15 41192167 41192167 single base substitution G T downstream_gene_variant PACA-AU 15 41192167 41192167 single base substitution G T intron_variant PACA-AU 15 41192167 41192167 single base substitution G T missense_variant R384L 1151G>T PACA-AU 15 41192320 41192320 single base substitution G A downstream_gene_variant PACA-AU 15 41192320 41192320 single base substitution G A intron_variant PACA-AU 15 41192320 41192320 single base substitution G A missense_variant R435H 1304G>A PACA-AU 15 41195989 41195989 single base substitution C T 3_prime_UTR_variant PACA-AU 15 41195989 41195989 single base substitution C T downstream_gene_variant PACA-AU 15 41200858 41200858 single base substitution T A downstream_gene_variant PACA-CA 15 41183933 41183933 single base substitution C G upstream_gene_variant PACA-CA 15 41185093 41185093 single base substitution G A upstream_gene_variant PACA-CA 15 41185524 41185524 single base substitution C T upstream_gene_variant PACA-CA 15 41185895 41185895 single base substitution G A upstream_gene_variant PACA-CA 15 41186392 41186392 single base substitution A T upstream_gene_variant PACA-CA 15 41187103 41187103 single base substitution T G intron_variant PACA-CA 15 41187402 41187402 single base substitution C G intron_variant PACA-CA 15 41187513 41187513 single base substitution T C intron_variant PACA-CA 15 41191474 41191474 single base substitution C T 3_prime_UTR_variant PACA-CA 15 41191474 41191474 single base substitution C T intron_variant PACA-CA 15 41191474 41191474 single base substitution C T missense_variant T153M 458C>T PACA-CA 15 41191734 41191734 single base substitution G C downstream_gene_variant PACA-CA 15 41191734 41191734 single base substitution G C intron_variant PACA-CA 15 41191734 41191734 single base substitution G C missense_variant E240Q 718G>C PACA-CA 15 41195388 41195388 single base substitution C T downstream_gene_variant PACA-CA 15 41195388 41195388 single base substitution C T missense_variant T924M 2771C>T PACA-CA 15 41197994 41197994 single base substitution G A downstream_gene_variant PACA-CA 15 41197995 41197995 single base substitution C A downstream_gene_variant PBCA-DE 15 41182526 41182526 insertion of <=200bp - T upstream_gene_variant PBCA-DE 15 41184110 41184110 single base substitution G A upstream_gene_variant PBCA-DE 15 41184876 41184876 single base substitution C T upstream_gene_variant PBCA-DE 15 41194688 41194688 insertion of <=200bp - G downstream_gene_variant PBCA-DE 15 41194688 41194688 insertion of <=200bp - G intron_variant PBCA-DE 15 41195879 41195880 deletion of <=200bp GA - 3_prime_UTR_variant PBCA-DE 15 41195879 41195880 deletion of <=200bp GA - downstream_gene_variant PRAD-CA 15 41183621 41183621 single base substitution C G upstream_gene_variant PRAD-CA 15 41184734 41184734 single base substitution T C upstream_gene_variant PRAD-UK 15 41186744 41186744 single base substitution G C 5_prime_UTR_variant PRAD-UK 15 41188566 41188566 single base substitution C A intron_variant PRAD-US 15 41192240 41192240 single base substitution C T downstream_gene_variant PRAD-US 15 41192240 41192240 single base substitution C T intron_variant PRAD-US 15 41192240 41192240 single base substitution C T synonymous_variant F408F 1224C>T RECA-EU 15 41184452 41184452 single base substitution C T upstream_gene_variant RECA-EU 15 41191656 41191656 single base substitution C T downstream_gene_variant RECA-EU 15 41191656 41191656 single base substitution C T intron_variant RECA-EU 15 41191656 41191656 single base substitution C T missense_variant P214S 640C>T SKCA-BR 15 41182000 41182000 single base substitution G A upstream_gene_variant SKCA-BR 15 41183127 41183127 single base substitution C T upstream_gene_variant SKCA-BR 15 41184429 41184429 single base substitution G A upstream_gene_variant SKCA-BR 15 41185207 41185207 single base substitution C T upstream_gene_variant SKCA-BR 15 41185839 41185839 single base substitution G A upstream_gene_variant SKCA-BR 15 41190723 41190723 single base substitution A G intron_variant SKCA-BR 15 41190930 41190930 single base substitution C T exon_variant SKCA-BR 15 41190930 41190930 single base substitution C T intron_variant SKCA-BR 15 41192668 41192668 single base substitution G A downstream_gene_variant SKCA-BR 15 41192668 41192668 single base substitution G A intron_variant SKCA-BR 15 41192668 41192668 single base substitution G A missense_variant G551E 1652G>A SKCA-BR 15 41197741 41197741 single base substitution C T downstream_gene_variant SKCM-US 15 41188156 41188156 single base substitution G A exon_variant SKCM-US 15 41188156 41188156 single base substitution G A missense_variant E38K 112G>A SKCM-US 15 41191361 41191361 single base substitution C T 3_prime_UTR_variant SKCM-US 15 41191361 41191361 single base substitution C T intron_variant SKCM-US 15 41191361 41191361 single base substitution C T synonymous_variant A115A 345C>T SKCM-US 15 41191637 41191637 single base substitution C T downstream_gene_variant SKCM-US 15 41191637 41191637 single base substitution C T intron_variant SKCM-US 15 41191637 41191637 single base substitution C T synonymous_variant S207S 621C>T SKCM-US 15 41191790 41191790 single base substitution C T downstream_gene_variant SKCM-US 15 41191790 41191790 single base substitution C T intron_variant SKCM-US 15 41191790 41191790 single base substitution C T synonymous_variant F258F 774C>T SKCM-US 15 41192210 41192210 single base substitution C T downstream_gene_variant SKCM-US 15 41192210 41192210 single base substitution C T intron_variant SKCM-US 15 41192210 41192210 single base substitution C T synonymous_variant V398V 1194C>T SKCM-US 15 41192240 41192240 single base substitution C T downstream_gene_variant SKCM-US 15 41192240 41192240 single base substitution C T intron_variant SKCM-US 15 41192240 41192240 single base substitution C T synonymous_variant F408F 1224C>T SKCM-US 15 41192313 41192313 single base substitution T C downstream_gene_variant SKCM-US 15 41192313 41192313 single base substitution T C intron_variant SKCM-US 15 41192313 41192313 single base substitution T C missense_variant C433R 1297T>C SKCM-US 15 41192378 41192378 single base substitution G A downstream_gene_variant SKCM-US 15 41192378 41192378 single base substitution G A intron_variant SKCM-US 15 41192378 41192378 single base substitution G A synonymous_variant E454E 1362G>A SKCM-US 15 41192646 41192646 single base substitution C T downstream_gene_variant SKCM-US 15 41192646 41192646 single base substitution C T intron_variant SKCM-US 15 41192646 41192646 single base substitution C T missense_variant H544Y 1630C>T SKCM-US 15 41194915 41194915 single base substitution A T 3_prime_UTR_variant SKCM-US 15 41194915 41194915 single base substitution A T downstream_gene_variant SKCM-US 15 41194915 41194915 single base substitution A T missense_variant E766D 2298A>T SKCM-US 15 41195002 41195002 single base substitution C T 3_prime_UTR_variant SKCM-US 15 41195002 41195002 single base substitution C T downstream_gene_variant SKCM-US 15 41195002 41195002 single base substitution C T synonymous_variant F795F 2385C>T SKCM-US 15 41195020 41195020 single base substitution C T 3_prime_UTR_variant SKCM-US 15 41195020 41195020 single base substitution C T downstream_gene_variant SKCM-US 15 41195020 41195020 single base substitution C T synonymous_variant F801F 2403C>T STAD-US 15 41188187 41188187 single base substitution G A exon_variant STAD-US 15 41188187 41188187 single base substitution G A missense_variant R48H 143G>A STAD-US 15 41191463 41191463 single base substitution G T 3_prime_UTR_variant STAD-US 15 41191463 41191463 single base substitution G T intron_variant STAD-US 15 41191463 41191463 single base substitution G T missense_variant K149N 447G>T STAD-US 15 41191563 41191563 single base substitution G A 3_prime_UTR_variant STAD-US 15 41191563 41191563 single base substitution G A intron_variant STAD-US 15 41191563 41191563 single base substitution G A missense_variant G183S 547G>A STAD-US 15 41191717 41191717 single base substitution G A downstream_gene_variant STAD-US 15 41191717 41191717 single base substitution G A intron_variant STAD-US 15 41191717 41191717 single base substitution G A missense_variant R234Q 701G>A STAD-US 15 41191772 41191772 single base substitution G A downstream_gene_variant STAD-US 15 41191772 41191772 single base substitution G A intron_variant STAD-US 15 41191772 41191772 single base substitution G A synonymous_variant T252T 756G>A STAD-US 15 41191837 41191837 deletion of <=200bp C - downstream_gene_variant STAD-US 15 41191837 41191837 deletion of <=200bp C - frameshift_variant T274 STAD-US 15 41191837 41191837 deletion of <=200bp C - intron_variant STAD-US 15 41191917 41191917 single base substitution C T downstream_gene_variant STAD-US 15 41191917 41191917 single base substitution C T intron_variant STAD-US 15 41191917 41191917 single base substitution C T missense_variant R301C 901C>T STAD-US 15 41192111 41192111 single base substitution G A downstream_gene_variant STAD-US 15 41192111 41192111 single base substitution G A intron_variant STAD-US 15 41192111 41192111 single base substitution G A synonymous_variant P365P 1095G>A STAD-US 15 41192112 41192112 single base substitution C T downstream_gene_variant STAD-US 15 41192112 41192112 single base substitution C T intron_variant STAD-US 15 41192112 41192112 single base substitution C T synonymous_variant L366L 1096C>T STAD-US 15 41192156 41192156 single base substitution C A downstream_gene_variant STAD-US 15 41192156 41192156 single base substitution C A intron_variant STAD-US 15 41192156 41192156 single base substitution C A synonymous_variant A380A 1140C>A STAD-US 15 41192607 41192607 single base substitution C T downstream_gene_variant STAD-US 15 41192607 41192607 single base substitution C T intron_variant STAD-US 15 41192607 41192607 single base substitution C T missense_variant R531C 1591C>T STAD-US 15 41192619 41192619 single base substitution T A downstream_gene_variant STAD-US 15 41192619 41192619 single base substitution T A intron_variant STAD-US 15 41192619 41192619 single base substitution T A missense_variant W535R 1603T>A STAD-US 15 41192635 41192635 single base substitution G A downstream_gene_variant STAD-US 15 41192635 41192635 single base substitution G A intron_variant STAD-US 15 41192635 41192635 single base substitution G A missense_variant R540Q 1619G>A STAD-US 15 41192724 41192724 single base substitution G A downstream_gene_variant STAD-US 15 41192724 41192724 single base substitution G A intron_variant STAD-US 15 41192724 41192724 single base substitution G A missense_variant V570M 1708G>A STAD-US 15 41192775 41192775 single base substitution G A downstream_gene_variant STAD-US 15 41192775 41192775 single base substitution G A intron_variant STAD-US 15 41192775 41192775 single base substitution G A missense_variant A587T 1759G>A STAD-US 15 41192972 41192972 single base substitution C T downstream_gene_variant STAD-US 15 41192972 41192972 single base substitution C T intron_variant STAD-US 15 41192972 41192972 single base substitution C T synonymous_variant C652C 1956C>T STAD-US 15 41192978 41192978 single base substitution C T downstream_gene_variant STAD-US 15 41192978 41192978 single base substitution C T intron_variant STAD-US 15 41192978 41192978 single base substitution C T synonymous_variant N654N 1962C>T STAD-US 15 41194934 41194934 single base substitution G A 3_prime_UTR_variant STAD-US 15 41194934 41194934 single base substitution G A downstream_gene_variant STAD-US 15 41194934 41194934 single base substitution G A missense_variant A773T 2317G>A UCEC-US 15 41191393 41191393 single base substitution G A 3_prime_UTR_variant UCEC-US 15 41191393 41191393 single base substitution G A intron_variant UCEC-US 15 41191393 41191393 single base substitution G A missense_variant R126Q 377G>A UCEC-US 15 41191502 41191502 single base substitution C T 3_prime_UTR_variant UCEC-US 15 41191502 41191502 single base substitution C T intron_variant UCEC-US 15 41191502 41191502 single base substitution C T synonymous_variant V162V 486C>T UCEC-US 15 41191586 41191586 single base substitution C T 3_prime_UTR_variant UCEC-US 15 41191586 41191586 single base substitution C T intron_variant UCEC-US 15 41191586 41191586 single base substitution C T synonymous_variant F190F 570C>T UCEC-US 15 41191854 41191854 single base substitution G A downstream_gene_variant UCEC-US 15 41191854 41191854 single base substitution G A intron_variant UCEC-US 15 41191854 41191854 single base substitution G A missense_variant A280T 838G>A UCEC-US 15 41192066 41192066 single base substitution C T downstream_gene_variant UCEC-US 15 41192066 41192066 single base substitution C T intron_variant UCEC-US 15 41192066 41192066 single base substitution C T synonymous_variant T350T 1050C>T UCEC-US 15 41192187 41192187 single base substitution G A downstream_gene_variant UCEC-US 15 41192187 41192187 single base substitution G A intron_variant UCEC-US 15 41192187 41192187 single base substitution G A missense_variant V391M 1171G>A UCEC-US 15 41192193 41192193 single base substitution C T downstream_gene_variant UCEC-US 15 41192193 41192193 single base substitution C T intron_variant UCEC-US 15 41192193 41192193 single base substitution C T missense_variant R393W 1177C>T UCEC-US 15 41192215 41192215 single base substitution G A downstream_gene_variant UCEC-US 15 41192215 41192215 single base substitution G A intron_variant UCEC-US 15 41192215 41192215 single base substitution G A missense_variant R400H 1199G>A UCEC-US 15 41192235 41192235 single base substitution C T downstream_gene_variant UCEC-US 15 41192235 41192235 single base substitution C T intron_variant UCEC-US 15 41192235 41192235 single base substitution C T missense_variant R407C 1219C>T UCEC-US 15 41192978 41192978 single base substitution C T downstream_gene_variant UCEC-US 15 41192978 41192978 single base substitution C T intron_variant UCEC-US 15 41192978 41192978 single base substitution C T synonymous_variant N654N 1962C>T UCEC-US 15 41194847 41194847 single base substitution C A downstream_gene_variant UCEC-US 15 41194847 41194847 single base substitution C A missense_variant L744M 2230C>A UCEC-US 15 41194847 41194847 single base substitution C A missense_variant P120H 359C>A UCEC-US 15 41195262 41195262 single base substitution C T downstream_gene_variant UCEC-US 15 41195262 41195262 single base substitution C T missense_variant A882V 2645C>T UCEC-US 15 41195414 41195414 single base substitution A T downstream_gene_variant UCEC-US 15 41195414 41195414 single base substitution A T stop_gained K933* 2797A>T

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-B0-5098-01 COSM1493384 c.1343T>C p.L448P Substitution - Missense 15:40900161-40900161 + 93VU147T COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + 41T COSM3734091 c.1207C>G p.L403V Substitution - Missense 15:40900025-40900025 + TCGA-AY-6197-01 COSM1372726 c.2592T>C p.P864P Substitution - coding silent 15:40903011-40903011 + TCGA-DA-A1HV-06 COSM3500970 c.345C>T p.A115A Substitution - coding silent 15:40899163-40899163 + CSCC-49-T COSM4508699 c.784C>T p.P262S Substitution - Missense 15:40899602-40899602 + pfg144T COSM4432597 c.524C>T p.S175L Substitution - Missense 15:40899342-40899342 + LS411 COSM2270012 c.2086G>A p.D696N Substitution - Missense 15:40900904-40900904 + TCGA-D1-A168-01 COSM470590 c.972A>C p.P324P Substitution - coding silent 15:40899790-40899790 + HT115 COSM2270020 c.2385C>T p.F795F Substitution - coding silent 15:40902804-40902804 + ESCC_167 COSM5648587 c.1983G>A p.Q661Q Substitution - coding silent 15:40900801-40900801 + TCGA-CD-A4MG-01 COSM4054440 c.1759G>A p.A587T Substitution - Missense 15:40900577-40900577 + CSCC-16-T COSM4589662 c.1702_1703insG p.V569fs*23 Insertion - Frameshift 15:40900520-40900521 + ESO-1488 COSM1232367 c.143G>A p.R48H Substitution - Missense 15:40895989-40895989 + TCGA-B5-A11E-01 COSM961317 c.1050C>T p.T350T Substitution - coding silent 15:40899868-40899868 + TCGA-E2-A14S-01 COSM433809 c.2281C>G p.R761G Substitution - Missense 15:40902700-40902700 + TCGA-F1-A448-01 COSM4054440 c.1759G>A p.A587T Substitution - Missense 15:40900577-40900577 + TCGA-ER-A193-06 COSM3500972 c.774C>T p.F258F Substitution - coding silent 15:40899592-40899592 + SNU-C4 COSM4652597 c.1185C>G p.A395A Substitution - coding silent 15:40900003-40900003 + TCGA-06-6390 COSM2153445 c.622C>T p.L208F Substitution - Missense 15:40899440-40899440 + I2L-P10-Tumor-Organoid COSM5362819 c.1225G>A p.D409N Substitution - Missense 15:40900043-40900043 + LUAD-RT-S01831 COSM384295 c.1550G>T p.R517L Substitution - Missense 15:40900368-40900368 + TCGA-EE-A2MR-06 COSM3500976 c.1630C>T p.H544Y Substitution - Missense 15:40900448-40900448 + T144 COSM307590 c.2895C>G p.Y965* Substitution - Nonsense 15:40903314-40903314 + SCC-15 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + AOCS-065-1-9 COSM3981481 c.2642A>C p.Q881P Substitution - Missense 15:40903061-40903061 + PCSI_0083_Pa_P COSM3377550 c.458C>T p.T153M Substitution - Missense 15:40899276-40899276 + TCGA-BR-8368-01 COSM4054431 c.547G>A p.G183S Substitution - Missense 15:40899365-40899365 + TCGA-AP-A051-01 COSM961325 c.2797A>T p.K933* Substitution - Nonsense 15:40903216-40903216 + UM-SCC-17B COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + HCC162 COSM3706551 c.2282G>T p.R761L Substitution - Missense 15:40902701-40902701 + MO_1215 COSM5572883 c.2837A>G p.Y946C Substitution - Missense 15:40903256-40903256 + TCGA-BR-6452-01 COSM4054430 c.447G>T p.K149N Substitution - Missense 15:40899265-40899265 + TCGA-HU-A4H4-01 COSM2270010 c.1956C>T p.C652C Substitution - coding silent 15:40900774-40900774 + Co108 COSM32907 c.2737G>T p.A913S Substitution - Missense 15:40903156-40903156 + T2940 COSM4740528 c.833G>A p.R278H Substitution - Missense 15:40899651-40899651 + CSCC-44-T COSM4473788 c.1873C>T p.Q625* Substitution - Nonsense 15:40900691-40900691 + CAL27 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + PCSI_0162_Pa_P_526 COSM4964268 c.718G>C p.E240Q Substitution - Missense 15:40899536-40899536 + HCT-15 COSM1678369 c.1063C>A p.L355M Substitution - Missense 15:40899881-40899881 + CHEWS017 COSM4578200 c.2100G>A p.A700A Substitution - coding silent 15:40900918-40900918 + YUHAM COSM5383239 c.2614C>T p.H872Y Substitution - Missense 15:40903033-40903033 + CSB14 COSM5027947 c.2278G>T p.A760S Substitution - Missense 15:40902697-40902697 + Pat_14_A COSM5849098 c.2063C>T p.A688V Substitution - Missense 15:40900881-40900881 + TCGA-HU-A4GN-01 COSM1232367 c.143G>A p.R48H Substitution - Missense 15:40895989-40895989 + 1013 COSM5730683 c.1340delC p.L448fs*1 Deletion - Frameshift 15:40900158-40900158 + TCGA-BH-A0AY-01 COSM433806 c.1310G>A p.R437H Substitution - Missense 15:40900128-40900128 + TCGA-KK-A5A1-01 COSM3500974 c.1224C>T p.F408F Substitution - coding silent 15:40900042-40900042 + cSCCP8 COSM140740 c.1738G>A p.E580K Substitution - Missense 15:40900556-40900556 + NOKSI COSM4595361 c.1573A>C p.T525P Substitution - Missense 15:40900391-40900391 + T1184 COSM2270020 c.2385C>T p.F795F Substitution - coding silent 15:40902804-40902804 + 587234 COSM1232369 c.1769G>A p.R590H Substitution - Missense 15:40900587-40900587 + TCGA-FS-A1ZZ-06 COSM3500974 c.1224C>T p.F408F Substitution - coding silent 15:40900042-40900042 + TCGA-EE-A2A2-06 COSM3500978 c.2403C>T p.F801F Substitution - coding silent 15:40902822-40902822 + MOLT-4 COSM1678368 c.1049C>T p.T350I Substitution - Missense 15:40899867-40899867 + 40 COSM4966103 c.1674C>A p.Y558* Substitution - Nonsense 15:40900492-40900492 + SCC-9 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + TCGA-61-2101-01 COSM80740 c.639C>T p.G213G Substitution - coding silent 15:40899457-40899457 + SNU-175 COSM1232367 c.143G>A p.R48H Substitution - Missense 15:40895989-40895989 + HCT15 COSM1678369 c.1063C>A p.L355M Substitution - Missense 15:40899881-40899881 + CSCC-11-T COSM4565929 c.2741_2742GG>AA p.R914Q Substitution - Missense 15:40903160-40903161 + OSCC-GB_00240111 COSM3711693 c.759C>A p.D253E Substitution - Missense 15:40899577-40899577 + CSCC-6-T COSM4537320 c.2406G>A p.K802K Substitution - coding silent 15:40902825-40902825 + CSCC-49-T COSM4532830 c.1923G>A p.Q641Q Substitution - coding silent 15:40900741-40900741 + STC252 COSM4740532 c.1725G>A p.Q575Q Substitution - coding silent 15:40900543-40900543 + PCSI_0625_Pa_P_526 COSM5761122 c.2771C>T p.T924M Substitution - Missense 15:40903190-40903190 + CAL33 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + TCGA-B5-A0JY-01 COSM961315 c.570C>T p.F190F Substitution - coding silent 15:40899388-40899388 + T2940 COSM187423 c.2495G>A p.R832H Substitution - Missense 15:40902914-40902914 + TCGA-AA-A02F-01 COSM300677 c.1377G>T p.K459N Substitution - Missense 15:40900195-40900195 + YUAKER COSM1708021 c.2605C>T p.L869F Substitution - Missense 15:40903024-40903024 + PD13760a COSM5786837 c.1086A>C p.K362N Substitution - Missense 15:40899904-40899904 + ESO-859 COSM1240634 c.1126G>T p.G376C Substitution - Missense 15:40899944-40899944 + WSU-HN8 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + BICR_22 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + T578 COSM4740531 c.1450G>A p.E484K Substitution - Missense 15:40900268-40900268 + B110 COSM1749121 c.1996T>C p.Y666H Substitution - Missense 15:40900814-40900814 + PD17981a COSM5767937 c.1713T>G p.A571A Substitution - coding silent 15:40900531-40900531 + H1155 COSM1195867 c.1262G>A p.C421Y Substitution - Missense 15:40900080-40900080 + sysucc-880T COSM5462452 c.2004G>A p.L668L Substitution - coding silent 15:40900822-40900822 + TCGA-CG-4306-01 COSM4054433 c.756G>A p.T252T Substitution - coding silent 15:40899574-40899574 + UM-SCC-2 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + CRC-02T COSM5454342 c.2824G>A p.A942T Substitution - Missense 15:40903243-40903243 + TCGA-JX-A3Q0-01 COSM4824404 c.1796C>T p.S599L Substitution - Missense 15:40900614-40900614 + TCGA-CG-5726-01 COSM4054438 c.1619G>A p.R540Q Substitution - Missense 15:40900437-40900437 + TCGA-CD-8525-01 COSM961322 c.1962C>T p.N654N Substitution - coding silent 15:40900780-40900780 + CRC-06T COSM5456477 c.1127G>A p.G376D Substitution - Missense 15:40899945-40899945 + T47 COSM1177562 c.2384T>G p.F795C Substitution - Missense 15:40902803-40902803 + ME045T COSM229567 c.2189C>T p.A730V Substitution - Missense 15:40901007-40901007 + TCGA-B0-5094-01 COSM470592 c.2292G>T p.V764V Substitution - coding silent 15:40902711-40902711 + TCGA-BT-A3PH-01 COSM1301085 c.1978G>A p.E660K Substitution - Missense 15:40900796-40900796 + TCGA-AX-A0J1-01 COSM961316 c.838G>A p.A280T Substitution - Missense 15:40899656-40899656 + TARGET-30-PANWRR COSM1288917 c.1916T>C p.V639A Substitution - Missense 15:40900734-40900734 + 41P3 COSM3734091 c.1207C>G p.L403V Substitution - Missense 15:40900025-40900025 + 2250219 COSM5029459 c.963G>A p.G321G Substitution - coding silent 15:40899781-40899781 + HCC101T COSM5813397 c.190A>T p.S64C Substitution - Missense 15:40896036-40896036 + LP6007523-DNA_A01 COSM5035877 c.1438T>C p.L480L Substitution - coding silent 15:40900256-40900256 + SC_9092 COSM4054434 c.1095G>A p.P365P Substitution - coding silent 15:40899913-40899913 + cSCCP4 COSM138959 c.625G>A p.E209K Substitution - Missense 15:40899443-40899443 + TCGA-AZ-6598-01 COSM1372723 c.356C>T p.T119M Substitution - Missense 15:40899174-40899174 + Pat_45_B COSM5849095 c.530G>A p.S177N Substitution - Missense 15:40899348-40899348 + 2250253 COSM5030340 c.1060G>C p.V354L Substitution - Missense 15:40899878-40899878 + C058 COSM5525809 c.2277C>T p.I759I Substitution - coding silent 15:40902696-40902696 + TCGA-AR-A0TU-01 COSM433810 c.2521C>T p.R841W Substitution - Missense 15:40902940-40902940 + TCGA-D1-A17Q-01 COSM961314 c.486C>T p.V162V Substitution - coding silent 15:40899304-40899304 + TCGA-C5-A3HE-01 COSM4827727 c.557C>T p.P186L Substitution - Missense 15:40899375-40899375 + 424 COSM4432597 c.524C>T p.S175L Substitution - Missense 15:40899342-40899342 + Pat_32_A COSM5849096 c.853G>A p.A285T Substitution - Missense 15:40899671-40899671 + CSCC-44-T COSM4465266 c.1374C>G p.L458L Substitution - coding silent 15:40900192-40900192 + N170T COSM236614 c.109C>A p.L37M Substitution - Missense 15:40895955-40895955 + CSCC-31-T COSM4482139 c.2577C>T p.P859P Substitution - coding silent 15:40902996-40902996 + HCT15 COSM2270021 c.2415C>T p.I805I Substitution - coding silent 15:40902834-40902834 + 587336 COSM1232367 c.143G>A p.R48H Substitution - Missense 15:40895989-40895989 + 13 COSM5732815 c.2299_2301delGAG p.E768delE Deletion - In frame 15:40902718-40902720 + T3080 COSM4740529 c.1330C>T p.R444C Substitution - Missense 15:40900148-40900148 + TCGA-D1-A0ZO-01 COSM961321 c.1219C>T p.R407C Substitution - Missense 15:40900037-40900037 + PD18048a COSM5790543 c.2270T>A p.L757Q Substitution - Missense 15:40902689-40902689 + TCGA-28-5215-01 COSM3401711 c.268G>A p.V90M Substitution - Missense 15:40898941-40898941 + TCGA-76-6282-01 COSM3401712 c.2028G>A p.P676P Substitution - coding silent 15:40900846-40900846 + TCGA-QB-A6FS-06 COSM3886924 c.1297T>C p.C433R Substitution - Missense 15:40900115-40900115 + CSB33 COSM5027948 c.2405A>G p.K802R Substitution - Missense 15:40902824-40902824 + HCT8 COSM4633967 c.1868C>T p.A623V Substitution - Missense 15:40900686-40900686 + TCGA-66-2793-01 COSM699909 c.1557C>G p.T519T Substitution - coding silent 15:40900375-40900375 + STC252 COSM5054271 c.1214T>C p.M405T Substitution - Missense 15:40900032-40900032 + TCGA-EE-A29V-06 COSM3500973 c.1194C>T p.V398V Substitution - coding silent 15:40900012-40900012 + I2L-P19Tb-Tumor-Organoid COSM5362991 c.545T>C p.F182S Substitution - Missense 15:40899363-40899363 + HN_62601 COSM128466 c.162C>T p.S54S Substitution - coding silent 15:40896008-40896008 + 587338 COSM1232368 c.901C>T p.R301C Substitution - Missense 15:40899719-40899719 + TCGA-BS-A0UV-01 COSM961313 c.377G>A p.R126Q Substitution - Missense 15:40899195-40899195 + SNU-C2B COSM2269988 c.1094C>T p.P365L Substitution - Missense 15:40899912-40899912 + TCGA-DA-A1I5-06 COSM3500975 c.1362G>A p.E454E Substitution - coding silent 15:40900180-40900180 + TCGA-AD-6964-01 COSM3754302 c.1309C>T p.R437C Substitution - Missense 15:40900127-40900127 + YUKLAB COSM1708020 c.1336T>C p.Y446H Substitution - Missense 15:40900154-40900154 + UD-SCC-2 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + T3724 COSM4740533 c.2305G>A p.D769N Substitution - Missense 15:40902724-40902724 + 24T COSM3711693 c.759C>A p.D253E Substitution - Missense 15:40899577-40899577 + KM12 COSM2269996 c.1346C>T p.T449I Substitution - Missense 15:40900164-40900164 + TCGA-CG-5726-01 COSM4054432 c.701G>A p.R234Q Substitution - Missense 15:40899519-40899519 + TCGA-E2-A1LS-01 COSM5229572 c.2075delG p.V693fs*28 Deletion - Frameshift 15:40900893-40900893 + sysucc-880T COSM5462453 c.2504G>A p.R835Q Substitution - Missense 15:40902923-40902923 + TCGA-BR-8591-01 COSM1232368 c.901C>T p.R301C Substitution - Missense 15:40899719-40899719 + CSCC-31-T COSM4501357 c.586C>T p.L196L Substitution - coding silent 15:40899404-40899404 + TCGA-EE-A181-06 COSM3500971 c.621C>T p.S207S Substitution - coding silent 15:40899439-40899439 + AOCS-065-3-6 COSM3981481 c.2642A>C p.Q881P Substitution - Missense 15:40903061-40903061 + T2197 COSM4740530 c.1435A>G p.S479G Substitution - Missense 15:40900253-40900253 + TCGA-CG-5726-01 COSM4054434 c.1095G>A p.P365P Substitution - coding silent 15:40899913-40899913 + TCGA-B0-4852-01 COSM470591 c.1150C>T p.R384W Substitution - Missense 15:40899968-40899968 + TCGA-BR-6852-01 COSM4054437 c.1591C>T p.R531C Substitution - Missense 15:40900409-40900409 + 8035693 COSM3386854 c.1304G>A p.R435H Substitution - Missense 15:40900122-40900122 + TCGA-BR-7851-01 COSM4054441 c.2317G>A p.A773T Substitution - Missense 15:40902736-40902736 + RK308_C01 COSM3744595 c.1409C>T p.A470V Substitution - Missense 15:40900227-40900227 + WSU-HN13 COSM4595361 c.1573A>C p.T525P Substitution - Missense 15:40900391-40900391 + I2L-P7-Tumor-Organoid COSM5363073 c.1240T>C p.Y414H Substitution - Missense 15:40900058-40900058 + BT-549 COSM1678371 c.1312C>T p.R438C Substitution - Missense 15:40900130-40900130 + C008 COSM5462453 c.2504G>A p.R835Q Substitution - Missense 15:40902923-40902923 + TCGA-BR-6566-01 COSM4054436 c.1140C>A p.A380A Substitution - coding silent 15:40899958-40899958 + I2L-P26-Tumor-Organoid COSM5363037 c.1716C>A p.Y572* Substitution - Nonsense 15:40900534-40900534 + LUAD-F00368 COSM341041 c.866G>A p.G289E Substitution - Missense 15:40899684-40899684 + TCGA-EB-A41B-01 COSM2270020 c.2385C>T p.F795F Substitution - coding silent 15:40902804-40902804 + TCGA-HU-A4G8-01 COSM4054435 c.1096C>T p.L366L Substitution - coding silent 15:40899914-40899914 + MEL-Ma-Mel-63 COSM1167736 c.2440_2441delCA p.H814fs*63 Deletion - Frameshift 15:40902859-40902860 + pfg125T COSM4753550 c.2522G>A p.R841Q Substitution - Missense 15:40902941-40902941 + DN12101 COSM5790543 c.2270T>A p.L757Q Substitution - Missense 15:40902689-40902689 + T2940 COSM4740532 c.1725G>A p.Q575Q Substitution - coding silent 15:40900543-40900543 + B110-Tumor COSM1749121 c.1996T>C p.Y666H Substitution - Missense 15:40900814-40900814 + PCSI_0083_Pa_P_526 COSM3377550 c.458C>T p.T153M Substitution - Missense 15:40899276-40899276 + C0097T COSM4150928 c.640C>T p.P214S Substitution - Missense 15:40899458-40899458 + PT29 COSM5906568 c.2499C>G p.I833M Substitution - Missense 15:40902918-40902918 + IGROV-1 COSM1678372 c.2278G>A p.A760T Substitution - Missense 15:40902697-40902697 + TCGA-33-4583-01 COSM699910 c.1304G>T p.R435L Substitution - Missense 15:40900122-40900122 + TCGA-BR-4362-01 COSM2270005 c.1603T>A p.W535R Substitution - Missense 15:40900421-40900421 + SCC-9 COSM4595361 c.1573A>C p.T525P Substitution - Missense 15:40900391-40900391 + PT44 COSM5926922 c.1588C>T p.P530S Substitution - Missense 15:40900406-40900406 + TCGA-B5-A0JZ-01 COSM961322 c.1962C>T p.N654N Substitution - coding silent 15:40900780-40900780 + TCGA-FW-A3TU-06 COSM3500969 c.112G>A p.E38K Substitution - Missense 15:40895958-40895958 + PR-00-1165 COSM248298 c.2043C>A p.A681A Substitution - coding silent 15:40900861-40900861 + CSCC-15-T COSM4496566 c.477C>T p.P159P Substitution - coding silent 15:40899295-40899295 + TCGA-BR-6452-01 COSM4054439 c.1708G>A p.V570M Substitution - Missense 15:40900526-40900526 + TCGA-CJ-4634-01 COSM3361366 c.214G>C p.G72R Substitution - Missense 15:40896060-40896060 + TCGA-23-1118-01 COSM76995 c.2056G>A p.A686T Substitution - Missense 15:40900874-40900874 + RMS66_ COSM4988240 c.1163G>A p.R388H Substitution - Missense 15:40899981-40899981 + HCT8 COSM1678369 c.1063C>A p.L355M Substitution - Missense 15:40899881-40899881 + Au1 COSM5597876 c.1953C>T p.F651F Substitution - coding silent 15:40900771-40900771 + DLD1 COSM1678369 c.1063C>A p.L355M Substitution - Missense 15:40899881-40899881 + C086 COSM5541586 c.1819C>T p.P607S Substitution - Missense 15:40900637-40900637 + 07-P075 COSM4578199 c.1025G>A p.R342Q Substitution - Missense 15:40899843-40899843 + Pat_63_B COSM5849094 c.164delA p.E55fs*15 Deletion - Frameshift 15:40896010-40896010 + TCGA-AP-A0LM-01 COSM961320 c.1199G>A p.R400H Substitution - Missense 15:40900017-40900017 + TCGA-D1-A103-01 COSM961324 c.2645C>T p.A882V Substitution - Missense 15:40903064-40903064 + CSCC-31-T COSM3500971 c.621C>T p.S207S Substitution - coding silent 15:40899439-40899439 + TCGA-B0-5693-01 COSM470590 c.972A>C p.P324P Substitution - coding silent 15:40899790-40899790 + MOLT-4 COSM1678370 c.1198C>T p.R400C Substitution - Missense 15:40900016-40900016 + Pat_14_B COSM5849097 c.1051G>A p.G351R Substitution - Missense 15:40899869-40899869 + CML009T COSM5802796 c.2796C>A p.L932L Substitution - coding silent 15:40903215-40903215 + LIM2405 COSM4641921 c.1390C>T p.R464* Substitution - Nonsense 15:40900208-40900208 + pfg016T COSM1640225 c.1448C>T p.A483V Substitution - Missense 15:40900266-40900266 + TCGA-EJ-5509-01 COSM1129220 c.167G>A p.R56H Substitution - Missense 15:40896013-40896013 + 40M COSM5586989 c.848C>T p.A283V Substitution - Missense 15:40899666-40899666 + BK0015 COSM4185908 c.812C>T p.A271V Substitution - Missense 15:40899630-40899630 + 2293782 COSM4608546 c.421C>A p.L141M Substitution - Missense 15:40899239-40899239 + ORL-48 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + TCGA-ER-A193-06 COSM3500977 c.2298A>T p.E766D Substitution - Missense 15:40902717-40902717 + WSU-HN13 COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + HCC162T COSM3706551 c.2282G>T p.R761L Substitution - Missense 15:40902701-40902701 + TCGA-B5-A0JZ-01 COSM961318 c.1171G>A p.V391M Substitution - Missense 15:40899989-40899989 + TCGA-AP-A059-01 COSM961323 c.2230C>A p.L744M Substitution - Missense 15:40902649-40902649 + PT35 COSM4250862 c.2576C>T p.P859L Substitution - Missense 15:40902995-40902995 + C086 COSM5541587 c.2629G>T p.D877Y Substitution - Missense 15:40903048-40903048 + 8044630 COSM554863 c.1151G>T p.R384L Substitution - Missense 15:40899969-40899969 + NOKSI COSM4591168 c.1586G>C p.S529T Substitution - Missense 15:40900404-40900404 + CSCC-31-T COSM4468530 c.1548C>T p.Y516Y Substitution - coding silent 15:40900366-40900366 + TCGA-AA-A010-01 COSM286471 c.372G>T p.V124V Substitution - coding silent 15:40899190-40899190 + TCGA-BG-A0MQ-01 COSM961319 c.1177C>T p.R393W Substitution - Missense 15:40899995-40899995 + PCSI_0083_Pa_X COSM3377550 c.458C>T p.T153M Substitution - Missense 15:40899276-40899276 + 250LT COSM1129220 c.167G>A p.R56H Substitution - Missense 15:40896013-40896013 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.23876 15q14-q15 608551

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Synonymous p.P324P c.972A>C 15 41191988 RCCC A G Missense p.E658G c.1973A>G 15 41192989 CM A G Missense p.K802R c.2405A>G 15 41195022 BRCA A G Missense p.Y723C c.2168A>G 15 41193184 BRCA A T Missense p.E766D c.2298A>T 15 41194915 CM CA - Frameshift p.H814Pfs*63 c.2441_2442delAC 15 41195057 CM C G Missense p.R608G c.1822C>G 15 41192838 CM C G Missense p.R761G c.2281C>G 15 41194898 BRCA C G Synonymous p.L188L c.564C>G 15 41191580 HNSC C G Synonymous p.T519T c.1557C>G 15 41192573 LUSC C T Missense p.A483V c.1448C>T 15 41192464 STAD C T Missense p.A730V c.2189C>T 15 41193205 CM C T Missense p.L208F c.622C>T 15 41191638 GBM C T Missense p.P281L c.842C>T 15 41191858 CM C T Missense p.R191C c.571C>T 15 41191587 BRCA C T Missense p.R384W c.1150C>T 15 41192166 RCCC C T Missense p.R393W c.1177C>T 15 41192193 UCEC C T Missense p.R407C c.1219C>T 15 41192235 UCEC C T Missense p.R841W c.2521C>T 15 41195138 BRCA C T Synonymous p.A115A c.345C>T 15 41191361 CM C T Synonymous p.F258F c.774C>T 15 41191790 CM C T Synonymous p.F408F c.1224C>T 15 41192240 CM C T Synonymous p.F408F c.1224C>T 15 41192240 PRAD C T Synonymous p.F51F c.153C>T 15 41188197 CM C T Synonymous p.F801F c.2403C>T 15 41195020 CM C T Synonymous p.G213G c.639C>T 15 41191655 OV C T Synonymous p.N654N c.1962C>T 15 41192978 UCEC C T Synonymous p.S207S c.621C>T 15 41191637 CM C T Synonymous p.S54S c.162C>T 15 41188206 HNSC C T Synonymous p.S619S c.1857C>T 15 41192873 CM C T Synonymous p.V398V c.1194C>T 15 41192210 CM G A Missense p.A686T c.2056G>A 15 41193072 OV G A Missense p.E660K c.1978G>A 15 41192994 BLCA G A Missense p.R234Q c.701G>A 15 41191717 STAD G A Missense p.R437H c.1310G>A 15 41192326 BRCA G A Missense p.R48H c.143G>A 15 41188187 ESCA G A Missense p.R540Q c.1619G>A 15 41192635 STAD G A Missense p.V391M c.1171G>A 15 41192187 UCEC G A Missense p.V90M c.268G>A 15 41191139 GBM G A Nonsense p.W286* c.857G>A 15 41191873 CM G A Synonymous p.E454E c.1362G>A 15 41192378 CM G A Synonymous p.P365P c.1095G>A 15 41192111 STAD G A Synonymous p.P676P c.2028G>A 15 41193044 GBM G A Synonymous p.P676P c.2028G>A 15 41193044 LGG G A Synonymous p.T252T c.756G>A 15 41191772 STAD G C Missense p.G72R c.214G>C 15 41188258 RCCC G T Missense p.A760S c.2278G>T 15 41194895 BRCA G T Missense p.A913S c.2737G>T 15 41195354 COREAD G T Missense p.D748Y c.2242G>T 15 41194859 LUAD G T Missense p.G376C c.1126G>T 15 41192142 ESCA G T Missense p.K459N c.1377G>T 15 41192393 COREAD G T Missense p.R435L c.1304G>T 15 41192320 LUSC G T SpliceAcceptorSNV . c.92-1G>T 15 41188135 LUAD G T Synonymous p.V764V c.2292G>T 15 41194909 RCCC T C Missense p.V639A c.1916T>C 15 41192932 NB T G Missense p.Y414D c.1240T>G 15 41192256 STAD