PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UFL1 UBE2W 19690564 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G MGRN1 UBE2W 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RPS15 UBE2W 19549727 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RNF152 UBE2W 19690564 biogrid,intact exp P P P GP P P P P P P P P RPS23 UBE2W 19549727 intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE2W RMND5B 19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G POLR2H UBE2W 25436519 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W UHRF2 19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W RNF150 19690564 biogrid,intact exp GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G UBE2W TRIM31 19549727 biogrid,intact exp P P G GP P GP P P P P P P P GP P P P P GP P P GP P UBE2W TRIM31 19549727 biogrid,intact exp P P G GP P GP P P P P P P P GP P P P P GP P P GP P UBE2W RNF2 19549727 biogrid,intact exp P P P P GP P P P P P P P P P P P MAPT UBE2W 25436519 biogrid exp G GP G G G GP G GP GP G GP GP G GP G G GP G GP G G GP GP GP G G GP GP G UBE2W RNF14 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSTPIP1 UBE2W 25416956,21516116 biogrid,mint,intact exp G G GP G GP G GP GP G G G G GP G G UBE2W OTUB1 unassigned1260 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W SNURF 19690564 intact exp CDK6 UBE2W 26186194 biogrid exp G GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP G G GP GP GP GP G XIAP UBE2W 19549727,21113135 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP G GP G GP GP G UBE2W TRIM39 19549727 biogrid,intact exp P P P P P P P P P P P P P RNF166 UBE2W 19549727 biogrid,intact exp GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G GP GP G GP GP G RNF111 UBE2W 19549727,19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W RNF5 25416956,19549727 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBE2W RNF26 19549727,19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G UBE2W TRIM35 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G RNF10 UBE2W 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RNF220 UBE2W 19549727 intact exp G GP G G GP GP G G GP G GP GP GP G G G GP G GP G GP GP GP GP G G GP G G LRSAM1 UBE2W 19549727 biogrid,intact exp P GP G P GP G P GP G GP GP P GP P GP GP GP G P GP P P P GP P P G MUL1 UBE2W 19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBE2W RNF125 19549727 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G CADPS2 UBE2W 19690564 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ELAVL1 UBE2W 19322201 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G USHBP1 UBE2W 25416956 biogrid,intact exp P P P P P P P P P P P P UBE2W BIRC8 19549727 biogrid,intact exp P P P P P P P P P P P P P P P P P P UFM1 UBE2W 19690564 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G BIRC2 UBE2W 19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G UBE2W STUB1 23560854,21855799,21518764 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EED UBE2W 21900206 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G RNF123 UBE2W 19549727 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2W TRIM17 19549727 biogrid,intact exp P P P P P P P P P P P P P P P P P P GP MID1 UBE2W 19549727 biogrid,intact exp G G G GP G GP GP G GP G G G G GP GP G GP G GP G G GP GP G GP GP G UBE2W MKRN1 21900206 biogrid,mint,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G UBE2W DNMT3B 21900206 biogrid,mint,intact exp GP P G G GP GP G GP P GP GP GP P G GP GP GP GP G GP P GP GP GP GP GP GP MKRN3 UBE2W 19549727 biogrid,intact exp P P P P P P P P P P P P P P P P P P P ZNRF1 UBE2W 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W RNF114 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAP3K1 UBE2W 19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RNF8 UBE2W 19549727 biogrid,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G UBE2W TRIM2 19549727 biogrid,intact exp GP G G GP G G GP G G G G G G G GP G G G G G G G G G G AKR1C3 UBE2W 16169070 hprd,biogrid,i2d,mint,intact exp GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G G G GP P GP GP G UBE2W MARCH5 25416956,19549727 biogrid,intact exp G G G G G GP G G GP G GP G G G G G GP G G G G G GP G G G G G G RFWD3 UBE2W 19549727 biogrid,intact exp G G G G G G G G G G G G G G G G G G DTX3L UBE2W 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP G G GP G GP GP GP GP GP GP G UBE2W RNF115 19690564 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2W UBE2W 20061386 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DTX3 UBE2W 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP G G G GP GP GP P G G G GP GP GP GP GP GP G MARCH3 UBE2W 19549727 biogrid,intact exp G G G G GP GP G G GP G GP G G G G GP GP G GP G G GP GP GP GP GP GP GP G TRIM27 UBE2W 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CNOT4 UBE2W 19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PJA2 UBE2W 19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W BARD1 21965653,25436519 biogrid exp P G GP P P GP P P P GP G GP P G P P GP P GP P GP GP GP G UBE2W TRIM8 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RNF165 UBE2W 19690564 biogrid,intact exp P P G P GP P P G P GP P P P GP P G P GP P G P GP P P UBE2W AMFR 19549727,19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RNF103 UBE2W 19690564 biogrid,intact exp G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G G GP G G GP G GP GP G UBE2W ROPN1 25416956 biogrid,intact exp GP P P P GP P P P P P G P P P GP G P GP GP P P GP UBE2W RNF167 19690564 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP G G GP G GP GP G RNF138 UBE2W 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G UBA1 UBE2W 25527291,17597759 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W BFAR 19549727 biogrid,intact exp G GP G G G GP G GP GP G G G GP G G G GP G G G GP G G G G G GP G G BRCA1 UBE2W 21965653,19712108,25436519,17873885 biogrid exp P P G GP P P P P P P P GP P P P P P P P P P P GP UBOX5 UBE2W 19549727 biogrid,intact exp GP GP G G G GP G GP P G G G GP GP G P GP G G G G G GP P GP GP GP G G UBE2W RNF185 19549727 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G G G G GP G G GP GP G POLR2C UBE2W 16169070 hprd,biogrid,i2d,mint,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP G GP GP G UBE2W TOPORS 19690564 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W CHFR 19549727 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ZNRF4 UBE2W 19690564 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G UBE2W FANCL 19111657,21229326,19549727 biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MIB1 UBE2W 19690564, 23023127 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP GP G GP G GP GP G RNF4 UBE2W 19549727,23560854,19690564, 25402006 biogrid,intact exp, pred GP G G G G GP G GP GP G GP G G G G G GP GP G G GP GP GP GP G G GP GP G DZIP3 UBE2W 19549727, 23023127 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G P GP GP GP GP G GP GP G DHRSX UBE2W ortho G GP G GP P G G P G GP GP G G GP P GP GP G GP G G GP G GP GP G UBE2W N6AMT1 ortho GP GP G G GP GP G GP GP G GP GP GP P G GP GP P GP G P GP GP GP GP GP GP GP RNF40 UBE2W ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W TCF20 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE2W UBE2D4 25402006, 23023127 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G UBE2S UBE2W 23023127 pred G G G G G G G G GP G G G GP G G G G G G G G G G G GP G UBE2W CDC23 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W ITCH 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM21 UBE2W 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G AR UBE2W 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G GP G UBE2W UBQLN1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W UBE2T 23023127 pred G G G GP G GP P P P GP GP P GP P G GP P GP G CDC34 UBE2W 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W WWP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDC27 UBE2W 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SMAD7 UBE2W 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G UBE2W FAF1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SUMO3 UBE2W 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W NEDD4L 23023127 pred GP GP G GP G GP GP G GP G GP P G GP GP GP GP G GP GP G G GP G GP G AXIN1 UBE2W 25402006 pred GP GP G GP GP G P GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2A UBE2W 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD3 UBE2W 25402006 pred GP GP G G G GP G G G G G G GP GP G G GP G GP G GP G G G G G G G G UBE2L3 UBE2W 23023127 pred GP G G G G GP G GP GP G GP G G G G GP GP G GP G G G GP GP GP G GP GP G UBE2W ANAPC10 23023127 pred GP G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP GP GP GP G UBE2W DERL1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2H UBE2W 23023127 pred GP GP G G GP GP G GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PIN1 UBE2W 23023127 pred G GP G G GP GP G G GP G G G G GP G G GP G P G P GP G G G G GP GP G UBE2W AKTIP 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2B UBE2W 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2W RNF11 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W TRPS1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2N UBE2W 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE2W UBE2E2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2E3 UBE2W 25402006, 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G WWP2 UBE2W 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CD3D UBE2W 25402006 pred GP G G GP G GP G GP GP G GP G G G G G G G G GP G GP G G G PRKCG UBE2W 23023127 pred G G G G G GP G G G G G G G GP G G G G G G G G UBE2V2 UBE2W 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D2 UBE2W 25402006 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G UBE2R2 UBE2W 23023127 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G GP GP G G UCHL1 UBE2W 23023127 pred G G G G G GP G G GP G GP G G G G G GP G GP G G G G G G G G GP G UBE2I UBE2W 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G LNX1 UBE2W 23023127 pred GP G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP P GP GP UBE2K UBE2W 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2W PATZ1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD12 UBE2W 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2D3 UBE2W 25402006, 23023127 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G UBE2G2 UBE2W 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G UBE2M UBE2W 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBE2E1 UBE2W 25402006, 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G SKIL UBE2W 25402006 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP G G G GP GP GP GP GP G GP GP G UBE2D1 UBE2W 25402006 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G UBE2C UBE2W 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q96B02 P42330 two hybrid 16169070 - X 2 Q96B02 P42330 two hybrid 16169070 - X 2 Q96B02 P19387 two hybrid 16169070 - X 2 Q96B02 P19387 two hybrid 16169070 - X 2 Q13490 Q96B02 two hybrid array 19690564 physical association X 2 A0A024RBP0 Q96B02 two hybrid array 19549727 physical association X 2 Q9NS56 Q96B02 two hybrid array 19690564 physical association X 2 O43586 Q96B02 two hybrid 21516116 physical association X 2 O43586 Q96B02 two hybrid prey pooling approach 25416956 physical association X 2 O43586 Q96B02 two hybrid array 25416956 physical association X 2 O43586 Q96B02 validated two hybrid 25416956 physical association X 2 Q9NW38 Q96B02 two hybrid 19549727 physical association X 2 Q5VTB9 Q96B02 two hybrid 19549727 physical association X 2 Q9UKV5 Q96B02 two hybrid array 19549727 physical association X 2 Q9UKV5 Q96B02 two hybrid array 19690564 physical association X 2 Q96EQ8 Q96B02 two hybrid array 19549727 physical association X 2 Q13064 Q96B02 two hybrid array 19549727 physical association X 2 Q96B02 P19387 two hybrid pooling approach 16169070 physical association X 2 Q96B02 P42330 two hybrid pooling approach 16169070 physical association X 2 Q96B02 Q99496 two hybrid array 19549727 physical association X 2 Q96B02 A0A024RCQ4 two hybrid array 19549727 physical association X 2 Q96B02 Q2L6J1 two hybrid array 19549727 physical association X 2 Q96B02 Q9C040 two hybrid array 19549727 physical association X 2 Q96B02 Q6PCD5 two hybrid array 19549727 physical association X 2 Q96B02 A0A024RCP5 two hybrid array 19549727 physical association X 2 Q96B02 Q96P09 two hybrid array 19549727 physical association X 2 Q96B02 Q86UD3 two hybrid array 19549727 physical association X 2 Q96B02 A0A024RB96 two hybrid array 19549727 physical association X 2 Q96B02 A8K517 two hybrid 19549727 physical association X 2 Q96B02 Q86Y13 two hybrid 19549727 physical association X 2 Q96B02 Q5XPI4 two hybrid 19549727 physical association X 2 Q96B02 Q9BY78 two hybrid 19549727 physical association X 2 Q96B02 Q9UBS8 two hybrid array 19549727 physical association X 2 Q96B02 Q86Y13 two hybrid array 19549727 physical association X 2 Q96B02 Q9UPQ4 two hybrid array 19549727 physical association X 2 Q96B02 A0A024R3T1 two hybrid array 19549727 physical association X 2 Q96B02 Q9BZR9 two hybrid array 19549727 physical association X 2 Q96B02 Q8TDB6 two hybrid array 19549727 physical association X 2 Q96B02 A0A024RAA0 two hybrid array 19690564 physical association X 2 Q96B02 Q13233 two hybrid array 19690564 physical association X 2 Q96B02 O43164 two hybrid array 19690564 physical association X 2 Q96B02 Q8N8N0 two hybrid array 19690564 physical association X 2 Q96B02 Q9BY78 two hybrid array 19690564 physical association X 2 Q96B02 Q96PU4 two hybrid array 19690564 physical association X 2 Q96B02 Q9Y4L5 two hybrid array 19690564 physical association X 2 Q96B02 Q9UHC7 two hybrid 21900206 physical association X 2 Q96B02 A0A024R7H3 two hybrid prey pooling approach 25416956 physical association X 2 Q96B02 A0A024RCQ4 two hybrid prey pooling approach 25416956 physical association X 2 Q96B02 A0A024R7H3 two hybrid array 25416956 physical association X 2 Q96B02 A0A024RCQ4 two hybrid array 25416956 physical association X 2 Q96B02 A0A024R7H3 validated two hybrid 25416956 physical association X 2 Q96B02 A0A024RCQ4 validated two hybrid 25416956 physical association X 2 Q9H6Y7 Q96B02 two hybrid array 19690564 physical association X 2 Q9NX47 Q96B02 two hybrid array 19549727 physical association X 2 Q6ZSG1 Q96B02 two hybrid array 19690564 physical association X 2 Q9NX47 Q96B02 two hybrid prey pooling approach 25416956 physical association X 2 Q9NX47 Q96B02 two hybrid array 25416956 physical association X 2 Q9NX47 Q96B02 validated two hybrid 25416956 physical association X 2 Q96EP1 Q96B02 two hybrid array 19549727 physical association X 2 Q96EP1 Q96B02 two hybrid 19549727 physical association X 2 Q6ZNA4 Q96B02 two hybrid array 19549727 physical association X 2 Q6ZNA4 Q96B02 two hybrid array 19690564 physical association X 2 P98170 Q96B02 two hybrid array 19549727 physical association X 2 Q86YT6 Q96B02 two hybrid array 19690564 physical association X 2 Q9ULK6 Q96B02 two hybrid array 19690564 physical association X 2 Q8WVD3 Q96B02 two hybrid array 19549727 physical association X 2 Q96B02 P14373 two hybrid array 19549727 physical association X 2 Q96B02 P78317 two hybrid array 19549727 physical association X 2 Q96B02 O60291 two hybrid array 19549727 physical association X 2 Q96B02 Q9NZS9 two hybrid array 19549727 physical association X 2 Q96B02 Q9Y508 two hybrid array 19549727 physical association X 2 Q96B02 A0A024R870 two hybrid array 19549727 physical association X 2 Q96B02 A0A024R1F5 two hybrid array 19549727 physical association X 2 Q96B02 P62841 two hybrid 19549727 physical association X 2 Q96B02 Q9NZS9 two hybrid 19549727 physical association X 2 Q96B02 Q8ND25 two hybrid 19549727 physical association X 2 Q96B02 A0A024RBV4 two hybrid array 19549727 physical association X 2 Q96B02 O76064 two hybrid array 19549727 physical association X 2 Q96B02 O94941 two hybrid array 19549727 physical association X 2 Q96B02 Q8ND25 two hybrid array 19549727 physical association X 2 Q96B02 Q96A37 two hybrid array 19549727 physical association X 2 Q96B02 O94874 two hybrid array 19690564 physical association X 2 Q96B02 Q86UW7 two hybrid array 19690564 physical association X 2 Q96B02 A0A024R785 two hybrid array 19690564 physical association X 2 Q96B02 O00237 two hybrid array 19690564 physical association X 2 Q96B02 Q96G75 two hybrid array 19690564 physical association X 2 Q96B02 A0A024R0T6 two hybrid array 19690564 physical association X 2 Q96B02 Q8WWF5 two hybrid array 19690564 physical association X 2 Q96B02 Q9UBC3 two hybrid 21900206 physical association X 2 Q96B02 O75530 two hybrid 21900206 physical association X 2 Q96B02 Q9HAT0 two hybrid prey pooling approach 25416956 physical association X 2 Q96B02 Q9HAT0 two hybrid array 25416956 physical association X 2 Q96B02 Q9HAT0 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RNF220 UBE2W MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100918 prey bait UFL1 UBE2W MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_102679 prey bait UBE2W RNF167 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123705|UniProt_102694 bait|bait prey|prey DTX3L UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124119|UniProt_101178 prey|prey bait|bait AKR1C3 UBE2W MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0468(hprd)|(biogrid)|MI:0471(mint) UniProt_155897|MINT_62845|HPRD_29361|BIOGRID_93335|MINT_33903 bait|bait|-|bait|bait prey|prey|-|prey|prey BIRC2 UBE2W MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102681|BIOGRID_123692 prey|prey bait|bait UBE2W TRIM39 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101490|BIOGRID_124444 bait|bait prey|prey MUL1 UBE2W MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102682|BIOGRID_123693 prey|prey bait|bait UFM1 UBE2W MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_123690 prey bait PSTPIP1 UBE2W MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114843 prey bait PJA2 UBE2W MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102688|BIOGRID_123699 prey|prey bait|bait RNF166 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101175|BIOGRID_124190 prey|prey bait|bait ELAVL1 UBE2W MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_187599 bait prey RNF111 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid) 19549727,19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid)|(intact)|(biogrid) UniProt_101485|BIOGRID_124481|UniProt_102689|BIOGRID_123701 prey|prey|prey|prey bait|bait|bait|bait RNF10 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124473|UniProt_101476 prey|prey bait|bait RFWD3 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101486|BIOGRID_124469 prey|prey bait|bait DZIP3 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_124128|UniProt_100913|UniProt_101169 prey|prey|prey bait|bait|bait RNF8 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101167|BIOGRID_124215 prey|prey bait|bait XIAP UBE2W MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727,21113135 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid) BIOGRID_143888|UniProt_101471|BIOGRID_124237 bait|prey|prey prey|bait|bait UBE2W RNF26 MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid) 19549727,19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_123706|UniProt_102695|UniProt_100922 bait|bait|bait prey|prey|prey UBE2W TRIM31 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124547|UniProt_101480 bait|bait prey|prey UBE2W TRIM31 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124547|UniProt_101480 bait|bait prey|prey UBE2W TRIM8 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124105|UniProt_101174 bait|bait prey|prey CADPS2 UBE2W MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102683|BIOGRID_123694 prey|prey bait|bait MARCH3 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124312|UniProt_101493 prey|prey bait|bait UBOX5 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101171|BIOGRID_124047 prey|prey bait|bait UBE2W TRIM2 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124531|UniProt_101479 bait|bait prey|prey MIB1 UBE2W MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102687|BIOGRID_123698 prey|prey bait|bait TRIM27 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101470|BIOGRID_124460 prey|prey bait|bait EED UBE2W MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_158189|UniProt_178365|UniProt_157767 prey|prey|prey bait|bait|bait MAP3K1 UBE2W MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102686|BIOGRID_123697 prey|prey bait|bait CNOT4 UBE2W MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123695|UniProt_102685 prey|prey bait|bait MID1 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124142|UniProt_101168 prey|prey bait|bait RNF123 UBE2W MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100920 prey bait RNF152 UBE2W MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123703|UniProt_102692 prey|prey bait|bait UBE2W DNMT3B MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_178364|BIOGRID_158191|UniProt_157766 bait|bait|bait prey|prey|prey UBE2W RNF14 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124071|UniProt_101170 bait|bait prey|prey UBE2W RNF138 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101481|BIOGRID_124262 bait|bait prey|prey UBE2W BARD1 MI:0096(pull down) 21965653 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226141 prey bait UBE2W RNF5 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101477|BIOGRID_124293 bait|bait prey|prey UBE2W ZNRF4 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123711|UniProt_102699 bait|bait prey|prey RNF103 UBE2W MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102684|BIOGRID_123696 prey|prey bait|bait LRSAM1 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101489|BIOGRID_124350 prey|prey bait|bait UBE2W TRIM35 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101173|BIOGRID_124221 bait|bait prey|prey UBE2W RNF2 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124507|UniProt_101473 bait|bait prey|prey UBE2W RNF150 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102691|BIOGRID_123702 bait|bait prey|prey UBE2W STUB1 MI:0096(pull down)|MI:0415(enzymatic study) 21518764,23560854 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_160919|BIOGRID_272403 prey|prey bait|bait DTX3 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124321|UniProt_101495 prey|prey bait|bait UBE2W MKRN1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_158190|UniProt_178366|UniProt_157768 bait|bait|bait prey|prey|prey UBC UBE2W MI:0004(affinity chromatography technology) 21139048 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_171711 bait prey MKRN3 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101475|BIOGRID_124431 prey|prey bait|bait UBE2W AMFR MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727,19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(intact) UniProt_102680|BIOGRID_124106|BIOGRID_123691|UniProt_101166 bait|bait|bait|bait prey|prey|prey|prey MGRN1 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124415|UniProt_101478 prey|prey bait|bait UBE2W TRIM17 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101172|BIOGRID_124218 bait|bait prey|prey UBE2W RNF114 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101488|BIOGRID_124340 bait|bait prey|prey UBE2W SNURF MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_102696 bait prey UBE2W RNF115 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102700|BIOGRID_123710 bait|bait prey|prey ZNRF1 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_100921|UniProt_101176|BIOGRID_124081 prey|prey|prey bait|bait|bait RNF4 UBE2W MI:0018(two hybrid)|MI:0415(enzymatic study)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727,19690564,23560854 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact) BIOGRID_124278|BIOGRID_272400|BIOGRID_123707|UniProt_101474 prey|bait|prey|prey bait|prey|bait|bait UBE2W FANCL MI:0018(two hybrid)|MI:0090(protein complementation assay)|MI:0090(protein complementation assay)|MI:0090(protein complementation assay) 19549727,21229326 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(biogrid)|(biogrid)|(biogrid) UniProt_100916|BIOGRID_135864|BIOGRID_135865|BIOGRID_135866 bait|bait|prey|prey prey|prey|bait|bait UBE2W MARCH5 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124405|UniProt_101483 bait|bait prey|prey BRCA1 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 17873885,19712108,21965653 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_164368|BIOGRID_164376|BIOGRID_226147|BIOGRID_164358|BIOGRID_164348 bait|bait|bait|bait|bait prey|prey|prey|prey|prey UBE2W BIRC8 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101492|BIOGRID_124255 bait|bait prey|prey RNF165 UBE2W MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123704|UniProt_102693 prey|prey bait|bait RPS23 UBE2W MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100915 prey bait UBE2W UHRF2 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123709|UniProt_102698 bait|bait prey|prey UBE2W BFAR MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_124267|UniProt_100917|UniProt_101482 bait|bait|bait prey|prey|prey UBE2W RMND5B MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123700|UniProt_102690 bait|bait prey|prey UBE2W RNF185 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101491|BIOGRID_124502 bait|bait prey|prey UBE2W TOPORS MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123708|UniProt_102697 bait|bait prey|prey UBE2W CHFR MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_100919|UniProt_101487|BIOGRID_124370 bait|bait|bait prey|prey|prey UBE2W RNF125 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101484|BIOGRID_124258 bait|bait prey|prey RPS15 UBE2W MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100914 prey bait POLR2C UBE2W MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd) BIOGRID_94666|UniProt_155605|MINT_33692|MINT_62633|HPRD_30158 bait|bait|bait|bait|- prey|prey|prey|prey|-

PPI - HINT Gene A Gene B PMID Method Quality BRCA1 UBE2W 19712108,21965653,25436519,19712108,19712108 0018,0096,0096,0096,0114 LC CDK6 UBE2W 26186194 0004 HT UBE2W BARD1 21965653,25436519 0096,0096 LC UBE2W STUB1 23560854,21518764 0096,0096 LC CDK6 UBE2W 26186194 0004 HT BRCA1 UBE2W 19712108,21965653,25436519,19712108,19712108 0018,0096,0096,0096,0114 LC UBE2W BARD1 21965653,25436519 0096,0096 LC UBE2W STUB1 23560854,21518764 0096,0096 LC RNF103 UBE2W 19690564,19690564 0397,0018 HT MID1 UBE2W 19549727,19549727 0397,0018 HT PJA2 UBE2W 19690564,19690564 0397,0018 HT PSTPIP1 UBE2W 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT MGRN1 UBE2W 19549727,19549727 0397,0018 HT EED UBE2W 21900206 0018 HT RNF8 UBE2W 19549727,19549727 0397,0018 HT UFL1 UBE2W 19690564 0397 HT UBOX5 UBE2W 19549727,19549727 0397,0018 HT CNOT4 UBE2W 19690564,19690564 0397,0018 HT MAPT UBE2W 25436519 0114 LC TRIM27 UBE2W 19549727,19549727 0397,0018 HT POLR2C UBE2W 16169070,16169070 0018,0398 HT UBA1 UBE2W 25527291 0415 LC BRCA1 UBE2W 19712108,19712108,19712108,17873885 0018,0096,0114,0018 LC AKR1C3 UBE2W 16169070,16169070 0018,0398 HT POLR2H UBE2W 25436519 0114 LC UFM1 UBE2W 19690564 0018 HT RPS23 UBE2W 19549727 0018 HT RPS15 UBE2W 19549727 0018 HT RNF4 UBE2W 19549727,19549727,19690564 0397,0018,0018 HT XIAP UBE2W 21113135,19549727,19549727 0018,0397,0018 LC,HT MKRN3 UBE2W 19549727,19549727 0397,0018 HT MAP3K1 UBE2W 19690564,19690564 0397,0018 HT BIRC2 UBE2W 19690564,19690564 0397,0018 HT RNF220 UBE2W 19549727 0018 HT RNF123 UBE2W 19549727 0018 HT RFWD3 UBE2W 19549727,19549727 0397,0018 HT LRSAM1 UBE2W 19549727,19549727 0397,0018 HT RNF111 UBE2W 19690564,19549727,19549727,19690564 0397,0397,0018,0018 HT RNF165 UBE2W 19690564,19690564 0397,0018 HT MARCH3 UBE2W 19549727,19549727 0397,0018 HT CADPS2 UBE2W 19690564,19690564 0397,0018 HT DZIP3 UBE2W 19549727,19549727 0397,0018 HT MIB1 UBE2W 19690564,19690564 0397,0018 HT RNF10 UBE2W 19549727,19549727 0397,0018 HT USHBP1 UBE2W 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT RNF152 UBE2W 19690564,19690564 0397,0018 HT DTX3 UBE2W 19549727,19549727 0397,0018 HT ZNRF1 UBE2W 19549727,19549727 0397,0018 HT DTX3L UBE2W 19549727,19549727 0397,0018 HT RNF138 UBE2W 19549727,19549727 0397,0018 HT ZNRF4 UBE2W 19690564,19690564 0397,0018 HT MUL1 UBE2W 19690564,19690564 0397,0018 HT RNF166 UBE2W 19549727,19549727 0397,0018 HT UBE2W UBE2W 20061386,22496338 0415,0114 LC UBE2W CHFR 19549727,19549727 0397,0018 HT UBE2W RNF125 19549727,19549727 0397,0018 HT UBE2W RMND5B 19690564,19690564 0397,0018 HT UBE2W RNF185 19549727,19549727 0397,0018 HT UBE2W BIRC8 19549727,19549727 0397,0018 HT UBE2W UHRF2 19690564,19690564 0397,0018 HT UBE2W RNF2 19549727,19549727 0397,0018 HT UBE2W RNF5 19549727,25416956,25416956,25416956,25416956,19549727 0397,1112,0397,0018,1356,0018 HT UBE2W RNF26 19690564,19549727,19690564 0397,0018,0018 HT UBE2W TRIM8 19549727,19549727 0397,0018 HT UBE2W TRIM31 19549727,19549727 0397,0018 HT UBE2W TRIM2 19549727,19549727 0397,0018 HT UBE2W RNF167 19690564,19690564 0397,0018 HT UBE2W ROPN1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT UBE2W TRIM39 19549727,19549727 0397,0018 HT UBE2W TOPORS 19690564,19690564 0397,0018 HT UBE2W FANCL 21229326,21229326,19111657,19549727 0096,0090,0018,0018 LC,HT UBE2W MARCH5 19549727,25416956,25416956,25416956,25416956,19549727 0397,1112,0397,0018,1356,0018 HT UBE2W BFAR 19549727,19549727 0397,0018 HT UBE2W DNMT3B 21900206 0018 HT UBE2W RNF14 19549727,19549727 0397,0018 HT UBE2W MKRN1 21900206 0018 HT UBE2W AMFR 19690564,19549727,19549727,19690564 0397,0397,0018,0018 HT UBE2W RNF150 19690564,19690564 0397,0018 HT UBE2W STUB1 21855799 0415 LC UBE2W TRIM35 19549727,19549727 0397,0018 HT UBE2W RNF115 19690564,19690564 0397,0018 HT UBE2W RNF114 19549727,19549727 0397,0018 HT UBE2W TRIM17 19549727,19549727 0397,0018 HT UBE2W SNURF 19690564 0397 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q96B02 Q5XPI4 UBE2W RNF123 0.454 19549727 Q96B02 Q8N6Y0 UBE2W USHBP1 0.454 25416956 Q9HAT0 Q96B02 ROPN1 UBE2W 0.454 25416956 Q96B02 Q8N8N0 UBE2W RNF152 0.376 19690564 Q96B02 Q8N9I9 UBE2W DTX3 0.376 19549727 Q9HCM9 Q96B02 TRIM39 UBE2W 0.376 19549727 Q9NS56 Q96B02 TOPORS UBE2W 0.376 19690564 Q96B02 Q8TDB6 UBE2W DTX3L 0.376 19549727 Q9H6Y7 Q96B02 RNF167 UBE2W 0.376 19690564 Q9Y675 Q96B02 SNURF UBE2W 0.126 19690564 Q9Y4L5 Q96B02 RNF115 UBE2W 0.376 19690564 Q9Y508 Q96B02 RNF114 UBE2W 0.376 19549727 Q96B02 Q6ZNA4 UBE2W RNF111 0.554 19690564,19549727 Q96B02 P14373 UBE2W TRIM27 0.376 19549727 Q96B02 O95628 UBE2W CNOT4 0.376 19690564 Q9NZS9 Q96B02 BFAR UBE2W 0.583 19549727 Q9UKV5 Q96B02 AMFR UBE2W 0.554 19690564,19549727 Q96B02 Q8ND25 UBE2W ZNRF1 0.583 19549727 Q96B02 O60291 UBE2W MGRN1 0.286 19549727 Q96B02 O00237 UBE2W RNF103 0.286 19690564 Q96B02 O43586 UBE2W PSTPIP1 0.636 21516116,25416956 Q96B02 O15344 UBE2W MID1 0.286 19549727 Q96B02 O43164 UBE2W PJA2 0.286 19690564 Q96B02 P98170 UBE2W XIAP 0.569 19549727,21113135 Q96B02 Q6ZSG1 UBE2W RNF165 0.286 19690564 Q96B02 Q6PCD5 UBE2W RFWD3 0.286 19549727 Q96B02 Q86UD3 UBE2W MARCH3 0.286 19549727 Q9C040 Q96B02 TRIM2 UBE2W 0.286 19549727 Q96B02 Q96A37 UBE2W RNF166 0.286 19549727 Q96EQ8 Q96B02 RNF125 UBE2W 0.286 19549727 Q96G75 Q96B02 RMND5B UBE2W 0.286 19690564 Q9Y577 Q96B02 TRIM17 UBE2W 0.286 19549727 Q9UHC7 Q96B02 MKRN1 UBE2W 0.332 21900206 Q9NX47 Q96B02 MARCH5 UBE2W 0.61 19549727,25416956 Q9ULK6 Q96B02 RNF150 UBE2W 0.286 19690564 Q96EP1 Q96B02 CHFR UBE2W 0.583 19549727 Q96FW1 Q96B02 OTUB1 UBE2W 0.236 26752685 Q99728 Q96B02 BARD1 UBE2W 0.523 25436519,21965653 Q96B02 P22314 UBE2W UBA1 0.523 17597759,25527291 Q96B02 Q86Y13 UBE2W DZIP3 0.416 19549727 Q99942 Q96B02 RNF5 UBE2W 0.61 19549727,25416956 Q96B02 P38398 UBE2W BRCA1 0.891 25436519,17873885,21965653,19712108 Q96B02 Q8WVD3 UBE2W RNF138 0.376 19549727 Q96B02 Q8WWF5 UBE2W ZNRF4 0.376 19690564 Q96B02 Q969V5 UBE2W MUL1 0.376 19690564 Q96B02 O75530 UBE2W EED 0.332 21900206 Q96B02 O76064 UBE2W RNF8 0.286 19549727 Q96B02 O94874 UBE2W UFL1 0.236 19690564 Q96B02 O94941 UBE2W UBOX5 0.286 19549727 Q96B02 P10636 UBE2W MAPT 0.309 25436519 Q96B02 P19387 UBE2W POLR2C 0.286 16169070 Q96B02 P26442 UBE2W AMFR 0.126 19549727 Q96B02 P42330 UBE2W AKR1C3 0.286 16169070 Q96B02 P52434 UBE2W POLR2H 0.309 25436519 Q96B02 P61960 UBE2W UFM1 0.183 19690564 Q96B02 P62266 UBE2W RPS23 0.332 19549727 Q96B02 P62841 UBE2W RPS15 0.332 19549727 Q96B02 Q13064 UBE2W MKRN3 0.286 19549727 Q96B02 Q5VTB9 UBE2W RNF220 0.332 19549727 Q96B02 Q6UWE0 UBE2W LRSAM1 0.286 19549727 Q96B02 Q86UW7 UBE2W CADPS2 0.286 19690564 Q96B02 Q86YT6 UBE2W MIB1 0.286 19690564 Q96B02 Q8N5U6 UBE2W RNF10 0.286 19549727 Q96P09 Q96B02 BIRC8 UBE2W 0.286 19549727 Q96PU4 Q96B02 UHRF2 UBE2W 0.286 19690564 Q9BZY9 Q96B02 TRIM31 UBE2W 0.286 19549727 Q9BZY9 Q96B02 TRIM31 UBE2W 0.286 19549727 Q9NW38 Q96B02 FANCL UBE2W 0.814 19549727,21229326,19111657 Q9UBC3 Q96B02 DNMT3B UBE2W 0.332 21900206 Q9UBS8 Q96B02 RNF14 UBE2W 0.286 19549727 Q9UNE7 Q96B02 STUB1 UBE2W 0.523 21855799,23560854 Q9UPQ4 Q96B02 TRIM35 UBE2W 0.286 19549727 Q96GF1 Q96B02 RNF185 UBE2W 0.376 19549727 Q9BY78 Q96B02 RNF26 UBE2W 0.61 19690564,19549727 Q9BZR9 Q96B02 TRIM8 UBE2W 0.376 19549727 Q99496 Q96B02 RNF2 UBE2W 0.376 19549727 Q9ES00 Q96B02 UBE4B UBE2W 0.309 23509263 Q96B02 P78317 UBE2W RNF4 0.597 19549727,19690564,23560854 Q96B02 Q00534 UBE2W CDK6 0.126 26186194 Q96B02 Q15717 UBE2W ELAVL1 0.126 19322201 Q96B02 Q13490 UBE2W BIRC2 0.376 19690564 Q96B02 Q13233 UBE2W MAP3K1 0.376 19690564

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 RNF103 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database MID1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database PJA2 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database PSTPIP1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database MGRN1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database EED UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF8 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database UFL1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database UBOX5 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database UBE4B UBE2W MI:0362 inference MI:0461 interaction database CNOT4 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database UBC UBE2W MI:0045 experimental interaction detection MI:0461 interaction database MAPT UBE2W MI:0045 experimental interaction detection MI:0461 interaction database TRIM27 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database POLR2C UBE2W MI:0045 experimental interaction detection MI:0461 interaction database UBA1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database BRCA1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database HNF4A UBE2W MI:0045 experimental interaction detection MI:0461 interaction database AKR1C3 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database POLR2H UBE2W MI:0045 experimental interaction detection MI:0461 interaction database UFM1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RPS23 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RPS15 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF4 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database XIAP UBE2W MI:0045 experimental interaction detection MI:0461 interaction database CDK6 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database MKRN3 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database MAP3K1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database BIRC2 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF220 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF123 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RFWD3 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database LRSAM1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF111 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF165 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database MARCH3 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database CADPS2 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database DZIP3 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database MIB1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF10 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database USHBP1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF152 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database DTX3 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database ZNRF1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database DTX3L UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF138 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database ZNRF4 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database MUL1 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF166 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database UBE2W CHFR MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF125 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W OTUB1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RMND5B MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF185 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W BIRC8 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W UHRF2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W BARD1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF26 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W TRIM8 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W TRIM31 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W TRIM2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF167 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W ROPN1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W TRIM39 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W TOPORS MI:0045 experimental interaction detection MI:0461 interaction database UBE2W FANCL MI:0045 experimental interaction detection MI:0461 interaction database UBE2W MARCH5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W BFAR MI:0045 experimental interaction detection MI:0461 interaction database UBE2W DNMT3B MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF14 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W MKRN1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W AMFR MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W STUB1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W TRIM35 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF115 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF114 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W TRIM17 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W SNURF MI:0045 experimental interaction detection MI:0461 interaction database