PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBXN8 VIMP 22119785 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G UBXN8 NXF1 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 GTF2F2 20195357 intact exp G G G G G G G G G G G G G G G G UBXN8 SYVN1 21949850 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 ADRB2 23798571 innatedb,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 VCP 18775313,25078495,21949850, 25402006 biogrid,intact exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 NPLOC4 18775313, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UFD1L 18775313, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 VCPIP1 18775313, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBTD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 SH3RF2 23023127 pred G G UBXN8 TRIM36 23023127 pred G G G G G G G G G G UBXN8 HERPUD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBFD1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBQLNL 23023127 pred G G UBXN8 PVRL3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 JOSD1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 CUEDC1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 NSFL1C 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 SVIP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBE4B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 FNDC3A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 FAF1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 VCX 23023127 pred UBXN8 MFF 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBC 23023127 pred UBXN8 RNF19A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 GGA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 OR10J1 23023127 pred G G G G G G G G G G G G UBXN8 UBQLN3 23023127 pred G G G G G G G G UBXN8 UBXN1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 AUP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBLCP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 TMUB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 TDRD3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBQLN2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 FCHSD2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 FAF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBXN2B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 SPTBN4 23023127 pred G G G G G G G G G UBXN8 ASPSCR1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 SH3RF3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBAP2L 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBXN8 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 MIDN 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 ACR 23023127 pred G G G G G G G G G G G G UBXN8 UBXN6 25402006 pred G G G G G G G G G G G G G G G G G G G G UBXN8 UBXN10 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBE2V2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 NPHP1 23023127 pred G G G G G G G UBXN8 UBTD1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 SUMO4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBXN7 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBL7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 TMUB1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 JOSD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 AMFR 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 STX2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 RAD23B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBXN4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 PPP2CB 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 UBQLN1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN8 RUSC2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A0A024R8R4 O00124 affinity chromatography technology 18775313 physical association X 2 P0CG48 O00124 affinity chromatography technology 24816145 physical association X 2 P0CG48 O00124 affinity chromatography technology 21890473 physical association X 2 P0CG48 O00124 affinity chromatography technology 21906983 physical association X 2 O00124 affinity chromatography technology 18775313 physical association X 2 Q9BQE4 O00124 affinity chromatography technology 22119785 physical association X 2 O00124 affinity chromatography technology 23798571 physical association X 2 Q96JH7 O00124 affinity chromatography technology 18775313 physical association X 2 P55072 O00124 two hybrid 21949850 direct interaction X 2 P55072 O00124 affinity chromatography technology 21949850 physical association X 2 P55072 O00124 affinity chromatography technology 18775313 physical association X 2 Q86TM6-3 O00124 affinity chromatography technology 21949850 physical association X 2 O00124 anti tag coimmunoprecipitation 18775313 association C 4 O00124 anti tag coimmunoprecipitation 18775313 association C 5 A0A024RDU9 O00124 display technology 20195357 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBXN8 VCP MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313,21949850 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_148721|BIOGRID_196034|BIOGRID_196035|UniProt_183186|UniProt_168923|UniProt_97377|UniProt_183197|UniProt_97388 bait|prey|bait|bait|bait|bait|bait|bait prey|bait|prey|prey|prey|prey|prey|prey UBXN8 UFD1L MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_148830|UniProt_168923|UniProt_183186|UniProt_97377|UniProt_183197|UniProt_97388 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey UBXN8 ADRB2 MI:0004(affinity chromatography technology) 23798571 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_282587 prey bait UBXN8 VCPIP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact)|(intact) BIOGRID_148831|UniProt_183186|UniProt_168923|UniProt_97377 bait|bait|bait|bait prey|prey|prey|prey UBXN8 GTF2F2 MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104678 prey bait UBXN8 NPLOC4 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_148829|UniProt_168923|UniProt_183186|UniProt_97377|UniProt_183197|UniProt_97388 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey UBXN8 UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21890473,21906983 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_176956|BIOGRID_172963 prey|prey bait|bait UBXN8 SYVN1 MI:0018(two hybrid) 21949850 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_196036 prey bait

PPI - HINT Gene A Gene B PMID Method Quality UBXN8 VCP 21949850,21949850,18775313,18775313 0018,0004,0004,0007 LC UBXN8 HEL-S-70 21949850,21949850,18775313,26389662 0018,0004,0004,0004 LC UBXN8 VCP 21949850,21949850,18775313,18775313 0018,0004,0004,0007 LC UBXN8 HEL-S-70 21949850,21949850,18775313,26389662 0018,0004,0004,0004 LC UBXN8 GTF2F2 20195357 0034 LC UBXN8 VCP 21949850,21949850 0018,0004 LC UBXN8 HEL-S-70 21949850,25078495,21949850 0018,0018,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9HA65 O00124 TBC1D17 UBXN8 0.126 26389662 Q9HCE1 O00124 MOV10 UBXN8 0.126 22658674 Q86TM6 O00124 SYVN1 UBXN8 0.21 21949850 P07550 O00124 ADRB2 UBXN8 0.126 23798571 O00124 A4D127 UBXN8 MEOX2 {ECO:0000313|EMBL:EAL24289.1} 0.236 unassigned1304 Q8TAT6 O00124 NPLOC4 UBXN8 0.236 18775313 Q96JH7 O00124 VCPIP1 UBXN8 0.236 18775313 Q92890 O00124 UFD1L UBXN8 0.236 18775313 P55072 O00124 VCP UBXN8 0.748 25078495,21949850,18775313,26389662 Q9BQE4 O00124 VIMP UBXN8 0.126 22119785 Q9UBU9 O00124 NXF1 UBXN8 0.126 22658674 O15260 O00124 SURF4 UBXN8 0.126 26389662 P12235 O00124 SLC25A4 UBXN8 0.126 26389662 P13984 O00124 GTF2F2 UBXN8 0.126 20195357 P20648 O00124 ATP4A UBXN8 0.126 26389662 P30825 O00124 SLC7A1 UBXN8 0.126 26389662 P43246 O00124 MSH2 UBXN8 0.126 26389662 Q01814 O00124 ATP2B2 UBXN8 0.126 26389662 Q12926 O00124 ELAVL2 UBXN8 0.126 26389662 Q6NTF9 O00124 RHBDD2 UBXN8 0.126 26389662 Q8TC07 O00124 TBC1D15 UBXN8 0.236 26389662 Q9H2H9 O00124 SLC38A1 UBXN8 0.126 26389662 Q9HC07 O00124 TMEM165 UBXN8 0.126 26389662 Q9P2R7 O00124 SUCLA2 UBXN8 0.126 26389662 Q9Y277 O00124 VDAC3 UBXN8 0.126 26389662 Q9Y6C9 O00124 MTCH2 UBXN8 0.126 26389662

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UBXN8 SURF4 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 MYC MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 ADRB2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 UBC MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 SLC25A4 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 GTF2F2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 ATP4A MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 TAF1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 SLC7A1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 MSH2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 VCP MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 MAX MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 ATP2B2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 ELAVL2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 RHBDD2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 SYVN1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 NPLOC4 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 TBC1D15 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 UFD1L MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 VCPIP1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 VIMP MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 SLC38A1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 TBC1D17 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 TMEM165 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 SUCLA2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 VDAC3 MI:0045 experimental interaction detection MI:0461 interaction database UBXN8 MTCH2 MI:0045 experimental interaction detection MI:0461 interaction database