PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus GRWD1 DTL 17041588 intact exp P P G GP P G P G P GP P G G G GP GRWD1 DDX24 26344197 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G RFWD2 GRWD1 17041588 intact exp G G G G G GP G G GP G G G G G G G GP G G G G G G G G G G G G UBC GRWD1 16196087 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G DOT1L GRWD1 20431927 biogrid exp G G G G G G G G G G G G G JUN GRWD1 25609649 intact exp GP GP G G G GP G G GP G GP G G G G GP GP G G G G G GP G GP G G G G GRWD1 GTPBP4 26344197 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G SNRNP40 GRWD1 17041588 intact exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 CDT1 18162579 biogrid exp P P G GP P G GP P P GP P GP G G P P GP G P G GRWD1 POLR1D 26344197 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G IFI16 GRWD1 25693804 biogrid exp G G G G GP GP G G GP G GP G G GP G G GP GP G G G G G G G G G G G GRWD1 GABARAPL1 20562859 intact exp GP GP G G GP GP G G GP G GP G G G G GP GP G G G G G GP GP GP G G GP G GRWD1 DIMT1 26344197 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 NXF1 22658674 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G TP53 GRWD1 23443559 biogrid exp G G G G G G G G G G G G G G G GP G G G G G G G G GP G G GP G GRB7 GRWD1 20007894 i2d exp GP GP G G GP GP G GP G GP G G GP G GP GP GP G G G G GP GP GP G GP G APC GRWD1 20007894 i2d exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G GP GP GP G G GP GRWD1 POLR1E 26344197 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 PRKAB1 17353931 intact exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G GRWD1 DDX18 26344197 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP G GP G G GP G GRK5 GRWD1 22952844 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 BCCIP 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VCP GRWD1 23443559 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRB2 GRWD1 12577067 intact exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G ESR1 GRWD1 20348541 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G CD247 GRWD1 24502978 intact exp G G GP G G G GP G G G G G G GRWD1 MAP1LC3A 20562859 intact exp G GP G G G GP G G GP G G G G G G GP GP G G G G G G G GP G G GP G CEP76 GRWD1 23443559 biogrid exp P P P P P P P P P P P P P GP HDGF GRWD1 21907836 biogrid,intact exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 PACSIN3 17353931 intact exp GP GP GP G G P P G G G GP GP GP G G G GP GP GP G P G MAP3K14 GRWD1 14743216 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MNDA GRWD1 25665578 intact exp G G G G GP G G G G G GP G G G G G G IKBKE GRWD1 17353931 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VHL GRWD1 21942715 biogrid exp G G G G G G G G G G GP G G G G G G G G G G GP G G G G GP G WDR5 GRWD1 17041588 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRWD1 WDR26 17041588 intact exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G EWSR1 GRWD1 24999758 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G CUL4B GRWD1 23238014,17041588 biogrid,intact exp GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G NPM1 GRWD1 23402259 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G WDR5B GRWD1 17041588 intact exp GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G GRWD1 DDX56 26344197 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G YBX1 GRWD1 25497084 intact exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G XPO1 GRWD1 26673895 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G CUL3 GRWD1 21145461 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GABARAP GRWD1 20562859 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRWD1 NOL10 26344197 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 SMURF2 20007894 i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRWD1 NOC2L 26344197 biogrid exp GP G G G GP GP G G GP G GP G G GP G G GP GP G G G G GP GP G G G GP G GRWD1 RBM19 26344197 biogrid exp P GP G G G GP G GP G GP G G GP G GP GP GP G G G G GP GP P G G GP G TOP1 GRWD1 12549820 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GABARAPL2 GRWD1 20562859 intact exp G GP G G GP GP G G GP G GP G G G G GP GP G G G G G GP G GP G G GP G CUL1 GRWD1 21145461 biogrid exp GP G G G G GP G G GP G GP G G G G GP GP GP G G G G GP GP GP G G GP G CEP57 GRWD1 23443559 biogrid exp GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G METTL18 GRWD1 23349634 biogrid exp GP GP G G GP GP G G GP G GP G G G G GP GP G G G G G GP G GP G G GP G COPS5 GRWD1 21145461, 25402006 biogrid exp, pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G WDR36 GRWD1 26344197, 21836163 biogrid exp, pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G G GP GP G G GP G DDB1 GRWD1 17079684, 25402006 biogrid exp, pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G CUL4A GRWD1 17041588,17079684, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CAND1 GRWD1 21145461, 25402006 biogrid exp, pred G GP G G G G G G GP G GP G G G G GP G GP G G G G GP GP GP G G GP G GRWD1 GRWD1 ortho GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G PES1 GRWD1 ortho GP G G G G GP G G GP G GP G G G G GP GP G G G G GP G G GP G H3F3C GRWD1 ortho P P P P P P P P P P P P P P KAT2B GRWD1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G RPS2 GRWD1 ortho G GP G G G GP G G GP G GP G G G G GP GP G G G G G GP GP GP G G GP G AMPD2 GRWD1 ortho G GP G G G GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G MAD2L1 GRWD1 ortho P G G P GP P GP G GP P G G P GP G G GP GRWD1 TYW1 ortho GP GP G G GP GP G G GP G GP G G G G GP GP G G G G G GP G GP G G GP G CNBP GRWD1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDK1 GRWD1 ortho GP G GP G GP P P GP GP G G G GP G G GP YWHAE GRWD1 ortho GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G RPS3 GRWD1 25402006, 21836163 ortho, pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP G GP G G GP G RPL3 GRWD1 25402006, 21836163 ortho, pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G RSL1D1 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 GAR1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G BYSL GRWD1 25402006, 21836163 pred GP GP G G GP GP G G GP G GP P G GP GP GP G G G GP GP GP GP G ATPAF2 GRWD1 21836163 pred GP GP G GP GP G G GP G GP G G GP G P GP GP G G G P GP P G GP G GRWD1 PTGES2 21836163 pred GP GP G G GP GP G G GP G GP G G GP GP GP GP G G G G GP GP GP G G GP G RPS18 GRWD1 25402006 pred GP GP G G GP GP G G G G GP G G GP G GP GP GP G G G G GP GP GP G G GP G SNRPD3 GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G BOP1 GRWD1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G GRWD1 ELP3 21836163 pred GP GP G G G GP G G GP G GP G G G G GP GP GP G G G G GP G GP G G GP G HIST1H1E GRWD1 25402006 pred P P G GP P P P P GP P P P P P P RPL7 GRWD1 25402006 pred GP G G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G RPL27A GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G PDCD5 GRWD1 21836163 pred G GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G RPL35 GRWD1 25402006 pred GP GP G G G GP G G GP G G G G GP G GP GP GP G G G G GP G GP G G GP G POLR2E GRWD1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RBX1 GRWD1 25402006 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G GP G GRWD1 PBDC1 21836163 pred GP GP G G GP GP G G GP G GP G G G G GP GP G G G G G GP GP GP G G GP G POLR2I GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G G G GP GP GP G G G G GP G GP G G GP G USP14 GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G RPL8 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 RSL24D1 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G MMGT1 GRWD1 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G TOP2A GRWD1 25402006 pred P P G GP GP GP GP G GP G G GP RPL18 GRWD1 25402006 pred GP G G G GP GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G TLE2 GRWD1 25402006 pred G GP G G G GP G G GP G GP G G GP G GP GP G G G G G G GP GP G G GP G BRIX1 GRWD1 21836163 pred GP G G GP GP G GP P GP G GP GP G G G G G GP GP GP G G GP RPS20 GRWD1 25402006 pred P P P P P P P P P P P P P RPS15A GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G G G GP GP GP G G G G GP GP GP G G GP G GRWD1 RPF2 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G G G G GP GP G G GP G PPP2R1A GRWD1 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G RPL14 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G RPL27 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G RARS GRWD1 21836163 pred GP GP G G G GP G G GP G G G G G G GP GP G G G G G GP G GP G G GP G GMNN GRWD1 25402006 pred GP G G G G G G G GP G G G G GP G GP G G G G G G G G GP G G GP G BOP1 GRWD1 21836163 pred RPS24 GRWD1 25402006 pred GP G G G G GP G G GP G G G G GP G GP GP G G G G G GP G GP G G GP G TSR1 GRWD1 25402006 pred GP GP G G GP G G G GP G GP G G GP G GP G GP G G G G GP GP GP G G GP G ALPL GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G G G GP GP G G G GP GP GP G G GP G RPL10L GRWD1 25402006 pred GP P G GP P G GP P G GP G GP P GP G G G GP P GP GP G STIP1 GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G RPL9, RPL9P7, RPL9P8, RPL9P9 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G UBXN7 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G GRWD1 MRPL17 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G MRPS35 GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G EIF3D GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G BMS1 GRWD1 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G SNRPD1 GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G WDSUB1 GRWD1 21836163 pred G G G G GP G G G G G GP G G G G G G G G G G G G G G G G GP G RRP12 GRWD1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TSN GRWD1 21836163 pred G GP G G G GP G G GP G GP G G G G GP GP G G G G G G G GP G G GP G WDR82 GRWD1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRWD1 WDR3 21836163 pred GP GP G G G GP G G GP G GP G G GP G G GP G G G G G G G G G G GP G RPS12 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G POLR1C GRWD1 21836163 pred G GP G G GP GP G G G G GP G G G G G GP G G G G G GP G G G G G G TBL3 GRWD1 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP P G G G G G GP GP G G GP G DDB2 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP G G GP G SND1 GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G PWP1 GRWD1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RPL13 GRWD1 25402006 pred P P G G GP GP GP G GP GP P GP P G G P GP P G GP G PHF5A GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G MCM6 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP GP GP G G GP G GRWD1 RBM22 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G CCNA1 GRWD1 25402006 pred G G G G G G G G G G G G G G G KRR1 GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G G G GP GP G G G G G GP GP GP G G GP G GRWD1 SDAD1 21836163 pred G G G G G GP G G GP G G G G G G G GP GP G G G G G G G G G GP G RPS17 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP G GP G G GP G NMD3 GRWD1 21836163 pred G GP G G G GP G G GP G GP G G G G GP GP G G G G G GP G GP G G G G RPL32 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G G G GP G GP G G GP G GRWD1 NIP7 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G EXOSC10 GRWD1 25402006, 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G PPP2R1B GRWD1 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G NOP56 GRWD1 21836163 pred P P P RBBP5 GRWD1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP GRWD1 DOHH 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP GP G G G G GP GP GP G G GP G SKP2 GRWD1 25402006 pred GP GP G G GP GP G G GP G G G G GP G GP GP G G G G G G GP GP G G GP G RPL22 GRWD1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRWD1 NAT10 21836163 pred GP GP G G G GP G G G G GP G G G G GP GP G G G G G G G GP G G GP G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CAND1 GRWD1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_206502 bait prey CUL1 GRWD1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_204733 bait prey HDGF GRWD1 MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification) 21907836 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0914(association) (intact)|(biogrid)|(intact) UniProt_115733|BIOGRID_182363|UniProt_115734 bait|bait|bait prey|prey|prey MAP3K14 GRWD1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 14743216 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(intact) MINT_87862|MINT_54248|UniProt_75162 bait|bait|bait prey|prey|prey NEDD8 GRWD1 MI:0004(affinity chromatography technology) 18247557 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_251594 bait prey TOP1 GRWD1 MI:0686(unspecified method) 12549820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_225812 bait prey CUL3 GRWD1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_202770 bait prey UBC GRWD1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16196087,21139048,21906983,21963094,21987572,22505724 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_265903|BIOGRID_143189|BIOGRID_225295|BIOGRID_163539|BIOGRID_180783|BIOGRID_171615 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey GRK5 GRWD1 MI:0004(affinity chromatography technology) 22952844 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_218438 bait prey VHL GRWD1 MI:0004(affinity chromatography technology) 21942715 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_164453 bait prey CUL4A GRWD1 MI:0006(anti bait coimmunoprecipitation)|MI:0401(biochemical)|MI:0004(affinity chromatography technology) 17041588,17079684 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid) UniProt_87648|BIOGRID_200219|BIOGRID_129006 bait|bait|bait prey|prey|prey NPM1 GRWD1 MI:0004(affinity chromatography technology) 23402259 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_274557 bait prey CUL4B GRWD1 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 17041588,23238014 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (intact)|(biogrid)|(biogrid)|(intact)|(intact) UniProt_87648|BIOGRID_129018|BIOGRID_129001|UniProt_87647|UniProt_126299 bait|bait|bait|bait|bait prey|prey|prey|prey|prey DOT1L GRWD1 MI:0004(affinity chromatography technology) 20431927 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_138176 bait prey WDR5 GRWD1 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17041588 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_87657|BIOGRID_129031 bait|prey prey|bait GRWD1 CDT1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18162579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_117704|BIOGRID_117730|BIOGRID_117717 prey|bait|prey bait|prey|bait COPS5 GRWD1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205233 bait prey GRWD1 BCCIP MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_243246 prey bait DDB1 GRWD1 MI:0401(biochemical) 17079684 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_200210 bait prey METTL18 GRWD1 MI:0004(affinity chromatography technology) 23349634 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_260213 bait prey

PPI - HINT Gene A Gene B PMID Method Quality JUN GRWD1 25609649 0006 HT GABARAPL2 GRWD1 20562859 0007 HT CUL1 GRWD1 21145461 0004 HT CUL3 GRWD1 21145461 0004 HT CUL4A GRWD1 17041588,17079684,17041588 0004,0004,0006 LC CUL4B GRWD1 17041588,23238014,17041588 0004,0007,0006 LC Q53GA5 GRWD1 23443559 0004 HT PCID2 GRWD1 20562859 0007 HT CAND1 GRWD1 21145461 0004 HT CEP57 GRWD1 23443559 0004 HT WDR36 GRWD1 26344197 0401 HT CEP76 GRWD1 23443559 0004 HT COPS5 GRWD1 21145461 0004 HT MAP3K14 GRWD1 14743216,14743216 0007,0676 HT GRWD1 NOL10 26344197 0401 HT GRWD1 GTPBP4 26344197 0401 HT GRWD1 DDX24 26344197 0401 HT GRWD1 POLR1E 26344197 0401 HT GRWD1 GABARAPL1 20562859 0007 HT GRWD1 MAP1LC3A 20562859 0007 HT GRWD1 DDX18 26344197 0401 HT GRWD1 DDX56 26344197 0401 HT GRWD1 BCCIP 22939629 0401 HT GRWD1 DIMT1 26344197 0401 HT GRWD1 POLR1D 26344197 0401 HT GRWD1 NOC2L 26344197 0401 HT GRWD1 RBM19 26344197 0401 HT GRWD1 HEL-S-70 23443559 0004 HT JUN GRWD1 25609649 0006 HT GABARAPL2 GRWD1 20562859 0007 HT CUL1 GRWD1 21145461 0004 HT CUL3 GRWD1 21145461 0004 HT Q53GA5 GRWD1 23443559 0004 HT PCID2 GRWD1 20562859 0007 HT CAND1 GRWD1 21145461 0004 HT CEP57 GRWD1 23443559 0004 HT WDR36 GRWD1 26344197 0401 HT CEP76 GRWD1 23443559 0004 HT COPS5 GRWD1 21145461 0004 HT MAP3K14 GRWD1 14743216,14743216 0007,0676 HT GRWD1 NOL10 26344197 0401 HT GRWD1 GTPBP4 26344197 0401 HT GRWD1 DDX24 26344197 0401 HT GRWD1 POLR1E 26344197 0401 HT GRWD1 GABARAPL1 20562859 0007 HT GRWD1 MAP1LC3A 20562859 0007 HT GRWD1 DDX18 26344197 0401 HT GRWD1 DDX56 26344197 0401 HT GRWD1 BCCIP 22939629 0401 HT GRWD1 DIMT1 26344197 0401 HT GRWD1 POLR1D 26344197 0401 HT GRWD1 NOC2L 26344197 0401 HT GRWD1 RBM19 26344197 0401 HT GRWD1 HEL-S-70 23443559 0004 HT CUL4A GRWD1 17041588,17079684,17041588 0004,0004,0006 LC CUL4B GRWD1 17041588,23238014,17041588 0004,0007,0006 LC WDR36 GRWD1 26344197 0401 LC GRWD1 NOL10 26344197 0401 LC GRWD1 GTPBP4 26344197 0401 LC GRWD1 DDX24 26344197 0401 LC GRWD1 POLR1E 26344197 0401 LC GRWD1 DDX18 26344197 0401 LC GRWD1 DDX56 26344197 0401 LC GRWD1 BCCIP 22939629 0401 LC GRWD1 DIMT1 26344197 0401 LC GRWD1 POLR1D 26344197 0401 LC GRWD1 NOC2L 26344197 0401 LC GRWD1 RBM19 26344197 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9BQ67 P60520 GRWD1 GABARAPL2 0.126 20562859 Q9BQ67 P23804 GRWD1 MDM2 0.126 24980433 Q9BQ67 Q8IZD2 GRWD1 KMT2E 0.21 26678539 Q9H492 Q9BQ67 MAP1LC3A GRWD1 0.126 20562859 Q9HCE1 Q9BQ67 MOV10 GRWD1 0.126 22658674 Q9BQ67 Q8NHY2 GRWD1 RFWD2 0.126 17041588 Q9BQ67 Q8NI36 GRWD1 WDR36 0.081 26344197 Q9H7D7 Q9BQ67 WDR26 GRWD1 0.126 17041588 Q9GZR7 Q9BQ67 DDX24 GRWD1 0.081 26344197 Q9BQ67 Q8TAP6 GRWD1 CEP76 0.126 23443559 Q9H0R8 Q9BQ67 GABARAPL1 GRWD1 0.126 20562859 Q9NVP1 Q9BQ67 DDX18 GRWD1 0.081 26344197 Q9NY93 Q9BQ67 DDX56 GRWD1 0.081 26344197 Q9BQ67 Q8TEK3 GRWD1 DOT1L 0.126 20431927 Q9NZJ0 Q9BQ67 DTL GRWD1 0.126 17041588 Q9Y2S0 Q9BQ67 POLR1D GRWD1 0.081 26344197 Q9BQ67 P0CG48 GRWD1 UBC 0.126 16196087 Q9BQ67 Q6P5F9 GRWD1 XPO1 0.126 26673895 Q9BQ67 Q86VP6 GRWD1 CAND1 0.126 21145461 Q9BQ67 Q86VZ2 GRWD1 WDR5B 0.126 17041588 Q9BQ67 Q86XR8 GRWD1 CEP57 0.126 23443559 Q9BQ67 P11387 GRWD1 TOP1 0.309 12549820 Q9BQ67 O95166 GRWD1 GABARAP 0.126 20562859 Q9BQ67 P03372 GRWD1 ESR1 0.183 20348541 Q9BQ67 O95568 GRWD1 METTL18 0.126 23349634 Q9BQ67 P04637 GRWD1 TP53 0.126 23443559 Q9BQ67 P05412 GRWD1 JUN 0.126 25609649 Q9BQ67 P06748 GRWD1 NPM1 0.126 23402259 Q9BQ67 P51858 GRWD1 HDGF 0.236 21907836 Q9BQ67 Q13619 GRWD1 CUL4A 0.396 17041588,17079684 Q9BQ67 Q13620 GRWD1 CUL4B 0.332 17041588,23238014 Q9BQ67 Q92905 GRWD1 COPS5 0.126 21145461 Q9BQ67 Q96DI7 GRWD1 SNRNP40 0.126 17041588 Q9BQ67 P61964 GRWD1 WDR5 0.236 17041588 Q9GZS1 Q9BQ67 POLR1E GRWD1 0.081 26344197 Q9H211 Q9BQ67 CDT1 GRWD1 0.569 18162579 Q9Y3T9 Q9BQ67 NOC2L GRWD1 0.081 26344197 Q9Y4C8 Q9BQ67 RBM19 GRWD1 0.081 26344197 Q9BSC4 Q9BQ67 NOL10 GRWD1 0.081 26344197 Q9BZE4 Q9BQ67 GTPBP4 GRWD1 0.081 26344197 Q9BQ67 Q99558 GRWD1 MAP3K14 0.126 14743216 Q9P287 Q9BQ67 BCCIP GRWD1 0.081 22939629 Q9UBU9 Q9BQ67 NXF1 GRWD1 0.126 22658674 Q9UNQ2 Q9BQ67 DIMT1 GRWD1 0.081 26344197 Q9BQ67 P34947 GRWD1 GRK5 0.126 22952844 Q9BQ67 P40337 GRWD1 VHL 0.126 21942715 Q9BQ67 P41218 GRWD1 MNDA 0.126 25665578 Q9BQ67 Q13616 GRWD1 CUL1 0.126 21145461 Q9BQ67 P14635 GRWD1 CCNB1 0.21 27030811 Q9BQ67 Q13618 GRWD1 CUL3 0.126 21145461 Q9BQ67 P62993 GRWD1 GRB2 0.126 12577067 Q9BQ67 Q01844 GRWD1 EWSR1 0.126 24999758 Q9BQ67 Q16531 GRWD1 DDB1 0.21 17079684 Q9BQ67 Q16666 GRWD1 IFI16 0.126 25693804 Q9BQ67 P55072 GRWD1 VCP 0.126 23443559

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PES1 GRWD1 MI:0362 inference MI:0461 interaction database XPO1 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database GABARAP GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database METTL18 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database ESR1 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database TP53 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database JUN GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database CDK1 GRWD1 MI:0362 inference MI:0461 interaction database NPM1 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 GRWD1 MI:0362 inference MI:0461 interaction database UBC GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database HSPA1A GRWD1 MI:0362 inference MI:0461 interaction database HSPA1B GRWD1 MI:0362 inference MI:0461 interaction database HSPA8 GRWD1 MI:0362 inference MI:0461 interaction database TOP1 GRWD1 MI:0362 inference MI:0461 interaction database RPS2 GRWD1 MI:0362 inference MI:0461 interaction database HSPA6 GRWD1 MI:0362 inference MI:0461 interaction database AMPD1 GRWD1 MI:0362 inference MI:0461 interaction database RPS3 GRWD1 MI:0362 inference MI:0461 interaction database HSPA1L GRWD1 MI:0362 inference MI:0461 interaction database GRK5 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database RPL3 GRWD1 MI:0362 inference MI:0461 interaction database VHL GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database MNDA GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database HNF4A GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database CDK8 GRWD1 MI:0362 inference MI:0461 interaction database HDGF GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database HMGA2 GRWD1 MI:0362 inference MI:0461 interaction database HSPA2 GRWD1 MI:0362 inference MI:0461 interaction database VCP GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database GABARAPL2 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database WDR5 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database RPS15A GRWD1 MI:0362 inference MI:0461 interaction database CNBP GRWD1 MI:0362 inference MI:0461 interaction database GRB2 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database SUMO1 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H3A GRWD1 MI:0362 inference MI:0461 interaction database H3F3A GRWD1 MI:0362 inference MI:0461 interaction database MDM2 GRWD1 MI:0362 inference MI:0461 interaction database AMPD3 GRWD1 MI:0362 inference MI:0461 interaction database AMPD2 GRWD1 MI:0362 inference MI:0461 interaction database EXOSC10 GRWD1 MI:0362 inference MI:0461 interaction database EWSR1 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database MAD2L1 GRWD1 MI:0362 inference MI:0461 interaction database CUL1 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database CUL4A GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database CUL4B GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database SF3B4 GRWD1 MI:0362 inference MI:0461 interaction database NEDD8 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database DDB1 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database IFI16 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database HIST3H3 GRWD1 MI:0362 inference MI:0461 interaction database H3F3C GRWD1 MI:0362 inference MI:0461 interaction database HIST2H3A GRWD1 MI:0362 inference MI:0461 interaction database CAND1 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database WDR5B GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database CEP57 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database KMT2E GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database CEP76 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database DOT1L GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database ZCCHC13 GRWD1 MI:0362 inference MI:0461 interaction database KAT2B GRWD1 MI:0362 inference MI:0461 interaction database RPL3L GRWD1 MI:0362 inference MI:0461 interaction database COPS5 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database SNRNP40 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K14 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database GRWD1 CDK19 MI:0362 inference MI:0461 interaction database GRWD1 GABARAPL1 MI:0045 experimental interaction detection MI:0461 interaction database GRWD1 CDT1 MI:0045 experimental interaction detection MI:0461 interaction database GRWD1 MAP1LC3A MI:0045 experimental interaction detection MI:0461 interaction database GRWD1 WDR26 MI:0045 experimental interaction detection MI:0461 interaction database GRWD1 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database GRWD1 MDN1 MI:0362 inference MI:0461 interaction database GRWD1 TYW1 MI:0362 inference MI:0461 interaction database GRWD1 DTL MI:0045 experimental interaction detection MI:0461 interaction database GRWD1 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database