PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus WDR91 CUL3 25011449 biogrid exp GP GP G G GP GP G P P G GP GP GP GP G P GP GP GP G GP GP GP GP GP GP GP GP G WDR91 SDCBP 16169070 hprd,i2d,mint,intact exp GP GP G G GP GP G P P G GP GP GP GP G P GP G GP G GP GP GP GP GP GP GP GP G WDR91 DLG3 26496610 biogrid,intact exp G G G G G GP G G GP G G G G GP G G G GP G G G G G GP GP G WDR91 STX8 16169070 hprd,i2d,mint,intact exp GP GP G G GP GP G P P G GP GP GP GP G P GP GP GP G GP GP GP GP GP GP GP GP G WDR91 ARIH2 16169070 hprd,biogrid,i2d,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G WDR91 SYNCRIP 26496610 biogrid,intact exp GP GP G G GP GP G P P G GP GP GP GP G P GP GP GP G GP GP GP GP GP GP GP GP G WDR91 BAG6 26496610 biogrid,intact exp GP GP G G GP GP G P P G GP GP GP GP G P GP GP GP G GP GP GP GP GP GP GP GP G WDR91 NTRK1 25921289 biogrid exp P P P G P P P P P P P P P P P P P P P WDR91 WWOX 24550385 biogrid exp GP GP G G GP GP G P P G GP GP GP GP G P GP G GP G GP GP GP GP GP GP GP GP G WDR91 XPO1 26673895 biogrid exp GP GP G G GP GP G P P G GP G GP GP G P GP GP GP G GP GP GP GP GP GP GP GP G WDR91 RAPGEF2 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G WDR91 HTT 17500595 intact exp GP GP G G GP GP G P G P GP P GP G P GP GP P G GP GP GP G GP GP GP GP WDR91 NUDC 25036637 intact exp GP GP G G GP GP G P G GP GP GP GP G P GP GP GP G GP GP GP G GP GP GP GP G WDR91 HUWE1 26496610 biogrid,intact exp GP GP G G GP GP G P P G GP GP GP GP G P GP GP GP G GP GP GP GP GP GP GP GP G WDR91 HP 21836163 pred G G G G G G G G GP G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A4D1P6 Q9NZC7-5 affinity chromatography technology 24550385 physical association X 2 A4D1P6 A0A024R475 affinity chromatography technology 25011449 physical association X 2 O95376 A4D1P6 two hybrid 16169070 direct interaction X 2 O00560-3 A4D1P6 two hybrid 16169070 - X 2 O00560-3 A4D1P6 two hybrid 16169070 - X 2 O95376 A4D1P6 two hybrid 16169070 - X 2 O95376 A4D1P6 two hybrid 16169070 - X 2 A4D1P6 Q9UNK0 two hybrid 16169070 - X 2 A4D1P6 Q9UNK0 two hybrid 16169070 - X 2 O95376 A4D1P6 two hybrid pooling approach 16169070 physical association X 2 P42858 A4D1P6 two hybrid 17500595 physical association X 2 A4D1P6 A0A024R7Z5 two hybrid pooling approach 16169070 physical association X 2 A4D1P6 Q9UNK0 two hybrid pooling approach 16169070 physical association X 2 A4D1P6 Q9Y266 luminescence based mammalian interactome mapping 25036637 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality WDR91 SYNCRIP 26496610 0007 HT WDR91 BAG6 26496610,26496610 0007,0004 HT WDR91 Q59GL1 26496610 0004 HT WDR91 HUWE1 26496610,26496610 0007,0004 HT WDR91 DLG3 26496610,26496610 0007,0004 HT WDR91 RAPGEF2 26496610,26496610 0007,0004 HT WDR91 SYNCRIP 26496610 0007 HT WDR91 BAG6 26496610,26496610 0007,0004 HT WDR91 Q59GL1 26496610 0004 HT WDR91 HUWE1 26496610,26496610 0007,0004 HT WDR91 DLG3 26496610,26496610 0007,0004 HT WDR91 RAPGEF2 26496610,26496610 0007,0004 HT WDR91 SDCBP 16169070,16169070 0018,0398 HT WDR91 ARIH2 16169070,16169070 0018,0398 HT WDR91 HTT 17500595 0018 LC WDR91 STX8 16169070,16169070 0018,0398 HT WDR91 NUDC 25036637 0729 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P61006 A4D1P6 RAB8A WDR91 0.126 26824392 Q9NZC7 A4D1P6 WWOX WDR91 0.126 24550385 Q80TP3 A4D1P6 UBR5 WDR91 0.126 26496610 Q6P5F9 A4D1P6 XPO1 WDR91 0.126 26673895 P04629 A4D1P6 NTRK1 WDR91 0.126 25921289 Q49A26 A4D1P6 GLYR1 WDR91 0.236 unassigned1304 Q13618 A4D1P6 CUL3 WDR91 0.21 25011449 O00560 A4D1P6 SDCBP WDR91 0.126 16169070 O95376 A4D1P6 ARIH2 WDR91 0.286 16169070 P42858 A4D1P6 HTT WDR91 0.183 17500595 Q9UNK0 A4D1P6 STX8 WDR91 0.126 16169070 Q9Y266 A4D1P6 NUDC WDR91 0.126 25036637 A4D1P6 A2AHJ4 WDR91 BRWD3 0.126 26496610

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 WDR91 SDCBP MI:0045 experimental interaction detection MI:0461 interaction database WDR91 XPO1 MI:0045 experimental interaction detection MI:0461 interaction database WDR91 SYNCRIP MI:0045 experimental interaction detection MI:0461 interaction database WDR91 UBR5 MI:0362 inference MI:0461 interaction database WDR91 ARIH2 MI:0045 experimental interaction detection MI:0461 interaction database WDR91 NTRK1 MI:0045 experimental interaction detection MI:0461 interaction database WDR91 HTT MI:0045 experimental interaction detection MI:0461 interaction database WDR91 BAG6 MI:0045 experimental interaction detection MI:0461 interaction database WDR91 CENPF MI:0362 inference MI:0461 interaction database WDR91 CUL3 MI:0045 experimental interaction detection MI:0461 interaction database WDR91 BRWD3 MI:0362 inference MI:0461 interaction database WDR91 HUWE1 MI:0045 experimental interaction detection MI:0461 interaction database WDR91 DLG3 MI:0045 experimental interaction detection MI:0461 interaction database WDR91 WWOX MI:0045 experimental interaction detection MI:0461 interaction database WDR91 STX8 MI:0045 experimental interaction detection MI:0461 interaction database WDR91 NUDC MI:0045 experimental interaction detection MI:0461 interaction database WDR91 RAPGEF2 MI:0045 experimental interaction detection MI:0461 interaction database